scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.275.12.8991 |
P698 | PubMed publication ID | 10722748 |
P2093 | author name string | S Lee | |
I Groulx | |||
M E Bonicalzi | |||
P2860 | cites work | Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function | Q22009393 |
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis | Q22009936 | ||
A nuclear export signal in hnRNP A1: a signal-mediated, temperature-dependent nuclear protein export pathway | Q24309825 | ||
The human poly(A)-binding protein 1 shuttles between the nucleus and the cytoplasm | Q24315066 | ||
Inhibition of Transcription Elongation by the VHL Tumor Suppressor Protein | Q24336629 | ||
Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C | Q24336712 | ||
Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2 | Q24523680 | ||
Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein | Q24530637 | ||
The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins | Q24564802 | ||
A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm | Q24609182 | ||
RanGTP-mediated nuclear export of karyopherin alpha involves its interaction with the nucleoporin Nup153 | Q24644181 | ||
CRM1 is an export receptor for leucine-rich nuclear export signals | Q27860453 | ||
A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export | Q27931607 | ||
The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs | Q28131708 | ||
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1 | Q28139243 | ||
Cancer-susceptibility genes. Gatekeepers and caretakers | Q28236512 | ||
Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms | Q28255553 | ||
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase | Q28506124 | ||
The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm | Q28646841 | ||
Identification of a signal for rapid export of proteins from the nucleus | Q29547742 | ||
A short amino acid sequence able to specify nuclear location | Q29547781 | ||
Nucleocytoplasmic transport: signals, mechanisms and regulation | Q29547904 | ||
Identification of the von Hippel-Lindau disease tumor suppressor gene | Q29618644 | ||
Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm | Q29618907 | ||
Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA | Q29620175 | ||
The GTP-binding protein Ran/TC4 is required for protein import into the nucleus | Q29620192 | ||
Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor | Q29620193 | ||
Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors | Q29620194 | ||
Evidence for a role of CRM1 in signal-mediated nuclear protein export | Q29620231 | ||
A cytosolic activity distinct from crm1 mediates nuclear export of protein kinase inhibitor in permeabilized cells. | Q30454343 | ||
Protective function of von Hippel-Lindau protein against impaired protein processing in renal carcinoma cells | Q33868951 | ||
The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein | Q33886877 | ||
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. | Q33888123 | ||
Somatic mutations of the von Hippel-Lindau disease tumour suppressor gene in non-familial clear cell renal carcinoma | Q34320299 | ||
The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal | Q34744818 | ||
The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix | Q34748818 | ||
pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation | Q34753344 | ||
ICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motif | Q35194372 | ||
The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity | Q35201819 | ||
A second major native von Hippel-Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor. | Q36222472 | ||
Subnuclear trafficking of glucocorticoid receptors in vitro: chromatin recycling and nuclear export | Q36274092 | ||
Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene | Q37285776 | ||
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein | Q37286026 | ||
Reconstitution of HIV-1 rev nuclear export: independent requirements for nuclear import and export | Q37477637 | ||
Nuclear/cytoplasmic localization of the von Hippel-Lindau tumor suppressor gene product is determined by cell density | Q37701211 | ||
Analysis of Ran/TC4 function in nuclear protein import | Q38300230 | ||
Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6 | Q39576878 | ||
Identification of the von Hippel-Lindau (VHL) gene. Its role in renal cancer | Q40580380 | ||
Subcellular localization of the von Hippel-Lindau disease gene product is cell cycle-dependent | Q41011329 | ||
Analysis of trafficking of Rev and transdominant Rev proteins in living cells using green fluorescent protein fusions: transdominant Rev blocks the export of Rev from the nucleus to the cytoplasm | Q41271927 | ||
Tumour suppression by the human von Hippel-Lindau gene product | Q41320477 | ||
Nucleocytoplasmic shuttling factors including Ran and CRM1 mediate nuclear export of NFAT In vitro | Q41961089 | ||
Alternate choice of initiation codon produces a biologically active product of the von Hippel Lindau gene with tumor suppressor activity | Q42469993 | ||
MPF localization is controlled by nuclear export | Q42649263 | ||
Mutations of the VHL tumour suppressor gene in renal carcinoma | Q42806703 | ||
Two-way trafficking with Ran. | Q47721385 | ||
Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis | Q57378150 | ||
Transcription-Dependent and Transcription-Independent Nuclear Transport of hnRNP Proteins | Q67923124 | ||
Immunostaining of the von Hippel-Lindau gene product in normal and neoplastic human tissues | Q73227598 | ||
RNA movement between the nucleus and the cytoplasm | Q73258077 | ||
Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis | Q74033395 | ||
The VHL tumour-suppressor gene paradigm | Q77572384 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 8991-9000 | |
P577 | publication date | 2000-03-01 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Ran-mediated nuclear export of the von Hippel-Lindau tumor suppressor protein occurs independently of its assembly with cullin-2 | |
P478 | volume | 275 |
Q42201994 | Antitumor effect and biological pathways of a recombinant adeno-associated virus as a human renal cell carcinoma suppressor |
Q36421050 | Cancer-causing mutations in a novel transcription-dependent nuclear export motif of VHL abrogate oxygen-dependent degradation of hypoxia-inducible factor. |
Q28576044 | Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death |
Q43761437 | Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation. |
Q40015100 | Mobility of the von Hippel-Lindau tumour suppressor protein is regulated by kinesin-2. |
Q28220414 | Molecular basis of the VHL hereditary cancer syndrome |
Q52551376 | Nuclear export of the glucocorticoid receptor is accelerated by cell fusion-dependent release of calreticulin. |
Q28647626 | Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein |
Q34530199 | Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL. |
Q35047240 | Regulation of tumor suppressors by nuclear-cytoplasmic shuttling |
Q28586399 | Regulation of ubiquitin ligase dynamics by the nucleolus |
Q35564185 | The von Hippel-Lindau Gene, Kidney Cancer, and Oxygen Sensing |
Q41612038 | The von Hippel-Lindau Tumor Suppressor Protein Is Destabilized by Src: Implications for Tumor Angiogenesis and Progression |
Q28203455 | The von Hippel-Lindau tumor suppressor gene |
Q34132816 | The von Hippel-Lindau tumor suppressor protein |
Q24676092 | Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import |
Q51971299 | Von Hippel-Lindau disease. |
Q24651660 | eEF1A is a novel component of the mammalian nuclear protein export machinery |
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