Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis

scientific article published on 01 January 1998

Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0960-9822(98)70039-9
P698PubMed publication ID9427645

P2093author name stringG Dreyfuss
S Nakielny
P2860cites workA novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complexQ24310068
Transportin-mediated nuclear import of heterogeneous nuclear RNP proteinsQ24312051
A novel class of RanGTP binding proteinsQ24316050
Export of importin alpha from the nucleus is mediated by a specific nuclear transport factorQ24316152
A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2Q24317523
Sequence and characterization of cytoplasmic nuclear protein import factor p97Q24318868
Karyopherin beta2 mediates nuclear import of a mRNA binding proteinQ24319692
A novel receptor-mediated nuclear protein import pathwayQ24324050
The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNAQ24339283
Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complexQ24532120
A nuclear localization domain in the hnRNP A1 proteinQ24672627
The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleusQ24678911
CRM1 is an export receptor for leucine-rich nuclear export signalsQ27860453
A distinct nuclear import pathway used by ribosomal proteinsQ27929963
Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteinsQ27932702
Exportin 1 (Crm1p) is an essential nuclear export factorQ27939696
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporinsQ28131733
Nuclear export receptors: from importin to exportinQ28250554
The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear exportQ28254641
Nucleocytoplasmic transportQ28275907
Transportin: nuclear transport receptor of a novel nuclear protein import pathwayQ28300708
Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporinsQ28573887
Nucleocytoplasmic transport: signals, mechanisms and regulationQ29547904
The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleusQ29616325
The GTP-binding protein Ran/TC4 is required for protein import into the nucleusQ29620192
Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factorQ29620193
Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factorsQ29620194
Evidence for a role of CRM1 in signal-mediated nuclear protein exportQ29620231
Nuclear protein importQ34426767
Functional domains in nuclear import factor p97 for binding the nuclear localization sequence receptor and the nuclear poreQ34669894
Structure and function of the nuclear pore complexQ35161320
Facilitated nuclear transport of calmodulin in tissue culture cellsQ36235026
A GTPase distinct from Ran is involved in nuclear protein importQ36236901
The hnRNP C proteins contain a nuclear retention sequence that can override nuclear export signalsQ36237427
GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein importQ36685432
Ran-unassisted nuclear migration of a 97-kD component of nuclear pore-targeting complexQ41075696
Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificitiesQ41079130
Requirement of guanosine triphosphate-bound ran for signal-mediated nuclear protein exportQ41104206
Nuclear export of proteins and RNAsQ41477073
RAN/TC4 mutants identify a common requirement for snRNP and protein import into the nucleusQ42772140
Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1Q72403668
Nuclear transport: proliferating pathwaysQ73159398
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)89-95
P577publication date1998-01-01
P1433published inCurrent BiologyQ1144851
P1476titleImport and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis
P478volume8

Reverse relations

cites work (P2860)
Q36379596A Crm1p-independent nuclear export path for the mRNA-associated protein, Npl3p/Mtr13p
Q28138319A human importin-beta family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins
Q24682010A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export
Q39819241Avian reovirus sigmaA localizes to the nucleolus and enters the nucleus by a nonclassical energy- and carrier-independent pathway
Q35850745CRM 1-mediated degradation and agonist-induced down-regulation of beta-adrenergic receptor mRNAs
Q31882249CRM1- and Ran-independent nuclear export of beta-catenin.
Q49485534Carrier-independent nuclear import of the transcription factor PU.1 via RanGTP-stimulated binding to Nup153.
Q36255858Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways
Q38302290Control of nuclear export of hnRNP A1.
Q40910811Distinct energy requirement for nuclear import and export of importin beta in living cells
Q24531945Export and transport of tRNA are coupled to a multi-protein complex
Q24554230Facilitated nucleocytoplasmic shuttling of the Ran binding protein RanBP1
Q24522554Functional conservation of the transportin nuclear import pathway in divergent organisms
Q47926605Functions of the GTPase Ran in RNA export from the nucleus
Q33688034Getting across the nuclear pore complex
Q42100280Heat-shock stress activates a novel nuclear import pathway mediated by Hikeshi
Q24317693Hikeshi, a nuclear import carrier for Hsp70s, protects cells from heat shock-induced nuclear damage
Q24314506Identification of a tRNA-specific nuclear export receptor
Q58801037Importin α: functions as a nuclear transport factor and beyond
Q24300253Inhibition of nuclear import by the proapoptotic protein CC3
Q27937378Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase
Q33938174Kinetic analysis of translocation through nuclear pore complexes
Q30454267Mechanism of Ca2+-dependent nuclear accumulation of calmodulin
Q34286042Molecular mechanism of translocation through nuclear pore complexes during nuclear protein import.
Q24548343Monoclonal antibodies to NTF2 inhibit nuclear protein import by preventing nuclear translocation of the GTPase Ran
Q24533395NTF2 mediates nuclear import of Ran.
Q39451343Nuclear import of IkappaBalpha is accomplished by a ran-independent transport pathway
Q35029558Nuclear transport kinetics in microarrays of nuclear envelope patches
Q24539168Nuclear transport: run by Ran?
Q35549198Nucleo-cytoplasmic partitioning of proteins in plants: implications for the regulation of environmental and developmental signalling
Q34486781Nucleo-cytoplasmic transport of proteins and RNA in plants
Q77944151Nucleocytoplasmic shuttling by protein nuclear import factors
Q41961089Nucleocytoplasmic shuttling factors including Ran and CRM1 mediate nuclear export of NFAT In vitro
Q35678324Nucleocytoplasmic shuttling of signal transducers.
Q47946232Nucleocytoplasmic transport: driving and directing transport
Q24534076Nup153 is an M9-containing mobile nucleoporin with a novel Ran-binding domain
Q42580368Phosphorylation of nucleoporins: signal transduction-mediated regulation of their interaction with nuclear transport receptors
Q77540888RNA trafficking in myelinating cells
Q28611866Ran-independent nuclear import of cyclin B1-Cdc2 by importin beta
Q73561184Ran-mediated nuclear export of the von Hippel-Lindau tumor suppressor protein occurs independently of its assembly with cullin-2
Q33959492RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase
Q52535120Real-time imaging of glucocorticoid receptor dynamics in living neurons and glial cells in comparison with non-neural cells.
Q57378150Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis
Q36323899Reconstitution of nuclear protein export in isolated nuclear envelopes
Q29619289Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle
Q30479838Reversibility in nucleocytoplasmic transport
Q24305124Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus
Q24537664Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains
Q40365923The 70-kD heat shock cognate protein (hsc70) facilitates the nuclear export of the import receptors
Q24534127The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human
Q36428044The direction of transport through the nuclear pore can be inverted
Q35827518The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2
Q48794579The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.
Q24534118The importin beta/importin 7 heterodimer is a functional nuclear import receptor for histone H1.
Q41889373The importin-beta binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro
Q34156668The molecular mechanism of transport of macromolecules through nuclear pore complexes
Q28139684The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import
Q39647313The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion
Q58077175The translocation of transportin–cargo complexes through nuclear pores is independent of both Ran and energy
Q24530637Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein
Q44624422Translocation of β-catenin into the nucleus independent of interactions with FG-rich nucleoporins
Q34467663Transport into and out of the cell nucleus
Q29615611Transport into and out of the nucleus
Q29619554Transport of proteins and RNAs in and out of the nucleus
Q24555219Transportin-SR2 mediates nuclear import of phosphorylated SR proteins
Q28640339beta-catenin can be transported into the nucleus in a Ran-unassisted manner

Search more.