The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus

scientific article

The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1083/JCB.111.2.309
P3181OpenCitations bibliographic resource ID3981455
P932PMC publication ID2116204
P698PubMed publication ID2116418
P5875ResearchGate publication ID277484743

P50authorAnita K. HopperQ89507889
P2093author name stringH M Traglia
R W Dunst
P2860cites workElectrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applicationsQ24561689
Transformation of intact yeast cells treated with alkali cationsQ24672708
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
A simple method for displaying the hydropathic character of a proteinQ26778481
Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localizationQ27937444
Saccharomyces cerevisiae tRNA ligase. Purification of the protein and isolation of the structural geneQ27937490
Structural rearrangements of tubulin and actin during the cell cycle of the yeast SaccharomycesQ27939365
Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factorQ28615489
Macromolecule Synthesis in Temperature-sensitive Mutants of YeastQ29616517
The heat-shock responseQ29619473
Splicing of messenger RNA precursorsQ29619934
Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiaeQ29620268
Sterile host yeasts (SHY): A eukaryotic system of biological containment for recombinant DNA experimentsQ29620758
Identification and nuclear localization of yeast pre-messenger RNA processing components: RNA2 and RNA3 proteinsQ36216616
Intracellular targeting and import of an F1-ATPase beta-subunit-beta-galactosidase hybrid protein into yeast mitochondriaQ36264055
Cloning and characterization of LOS1, a Saccharomyces cerevisiae gene that affects tRNA splicingQ36426631
A yeast mutant which accumulates precursor tRNAsQ36462811
PRP4 (RNA4) from Saccharomyces cerevisiae: its gene product is associated with the U4/U6 small nuclear ribonucleoprotein particleQ36759940
PRP4: a protein of the yeast U4/U6 small nuclear ribonucleoprotein particleQ36759976
Structural and functional analyses of Saccharomyces cerevisiae wild-type and mutant RNA1 genesQ36769701
RNA11 protein is associated with the yeast spliceosome and is localized in the periphery of the cell nucleusQ36790107
Temperature-sensitive Yeast Mutant Defective in Ribonucleic Acid ProductionQ36818923
Characterization of an essential Saccharomyces cerevisiae gene related to RNA processing: cloning of RNA1 and generation of a new allele with a novel phenotypeQ36888361
Amino acid sequences that determine the nuclear localization of yeast histone 2B.Q36923857
A suppressor of temperature-sensitive rna mutations that affect mRNA metabolism in Saccharomyces cerevisiaeQ36972987
Synthesis of ribosomes in Saccharomyces cerevisiaeQ37055496
Open reading frame expression vectors: a general method for antigen production in Escherichia coli using protein fusions to beta-galactosidase.Q37342929
The role of cytoplasmic membranes in controlling the transport of nuclear messenger RNA and initiation of protein synthesisQ37451301
Cytoplasmic anchoring proteins and the control of nuclear localizationQ38738339
Split tRNA genes and their products: a paradigm for the study of cell function and evolutionQ38762328
Nuclear pre-mRNA splicing in yeastQ38762332
Transfer RNA modificationQ39664935
Protein import into the cell nucleusQ39760608
Macromolecule synthesis and breakdown in relation to sporulation and meiosis in yeast.Q40089491
Transcription and processing of intervening sequences in yeast tRNA genesQ40908507
N2,N2-dimethylguanosine-specific tRNA methyltransferase contains both nuclear and mitochondrial targeting signals in Saccharomyces cerevisiaeQ41588921
Regulated overproduction of the GAL4 gene product greatly increases expression from galactose-inducible promoters on multi-copy expression vectors in yeastQ42501585
The organization and transcription of the galactose gene cluster of SaccharomycesQ43417624
Targeting of E. coli β-galactosidase to the nucleus in yeastQ44054614
A trans-acting suppressor restores splicing of a yeast intron with a branch point mutationQ44378546
Splicing of yeast nuclear pre-mRNA in vitro requires a functional 40S spliceosome and several extrinsic factorsQ46593105
The genes for fifteen ribosomal proteins of Saccharomyces cerevisiaeQ54529726
Identification of a yeast snRNP protein and detection of snRNP-snRNP interactionsQ63362935
Yeast mutation thought to arrest mRNA transport markedly increases the length of the 3' poly(A) on polyadenylated RNAQ69110489
Immunoaffinity chromatography of proteinsQ70029871
The effect of temperature-sensitive RNA mutants on the transcription products from cloned ribosomal protein genes of yeastQ70159118
Processing of intervening sequences: a new yeast mutant which fails to excise intervening sequences from precursor tRNAsQ71156037
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectGTPase-activating protein RNA1 YMR235CQ27550708
P304page(s)309-21
P577publication date1990-08-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleThe yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus
P478volume111

Reverse relations

cites work (P2860)
Q27936922A Los1p-independent pathway for nuclear export of intronless tRNAs in Saccharomycescerevisiae
Q50719993A Ran-independent pathway for export of spliced mRNA.
Q36894670A conditional yeast mutant deficient in mRNA transport from nucleus to cytoplasm
Q24555045A domain unique to plant RanGAP is responsible for its targeting to the plant nuclear rim
Q40365606A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif
Q27934656A member of the Ran-binding protein family, Yrb2p, is involved in nuclear protein export
Q38327705A monoclonal antibody to the COOH-terminal acidic portion of Ran inhibits both the recycling of Ran and nuclear protein import in living cells
Q39775920A non-canonical mechanism for Crm1-export cargo complex assembly
Q24316050A novel class of RanGTP binding proteins
Q27938372A novel nuclear import pathway for the transcription factor TFIIS.
Q24310068A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex
Q27937560A panoramic view of yeast noncoding RNA processing
Q24317523A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2
Q27937963Accelerating the rate of disassembly of karyopherin.cargo complexes
Q33940712Atomic basis of CRM1-cargo recognition, release and inhibition
Q24649967Biochemical Characterization of the Ran-RanBP1-RanGAP System: Are RanBP Proteins and the Acidic Tail of RanGAP Required for the Ran-RanGAP GTPase Reaction?
Q58456788Biotagging, an in vivo biotinylation approach for cell-type specific subcellular profiling in zebrafish
Q36385395Cellular dynamics of small RNAs
Q27931972Cex1p facilitates Rna1p-mediated dissociation of the Los1p-tRNA-Gsp1p-GTP export complex.
Q41079130Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities
Q24316332Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1
Q26851989Components and regulation of nuclear transport processes
Q34325429Coupling of termination, 3' processing, and mRNA export
Q27935016Crm1p mediates regulated nuclear export of a yeast AP-1-like transcription factor
Q27937989Dbp5p/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA export
Q49486091Disassembly of RanGTP-karyopherin beta complex, an intermediate in nuclear protein import
Q24532120Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex
Q36237107Dynamic localization of the nuclear import receptor and its interactions with transport factors
Q27931894Evidence for Gal3p's cytoplasmic location and Gal80p's dual cytoplasmic-nuclear location implicates new mechanisms for controlling Gal4p activity in Saccharomyces cerevisiae
Q24316152Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor
Q55412292Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore.
Q24554230Facilitated nucleocytoplasmic shuttling of the Ran binding protein RanBP1
Q56762936Functional Analysis of the Hydrophobic Patch on Nuclear Transport Factor 2 Involved in Interactions with the Nuclear Porein Vivo
Q38333740Functional characterization of a plant importin alpha homologue. Nuclear localization signal (NLS)-selective binding and mediation of nuclear import of nls proteins in vitro.
Q40819561GAP Activity, but Not Subcellular Targeting, Is Required for Arabidopsis RanGAP Cellular and Developmental Functions
Q27933501GLE2, a Saccharomyces cerevisiae homologue of the Schizosaccharomyces pombe export factor RAE1, is required for nuclear pore complex structure and function
Q36685432GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import
Q41789759Genetic and physical interactions between Srp1p and nuclear pore complex proteins Nup1p and Nup2p
Q24316235Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport
Q24314506Identification of a tRNA-specific nuclear export receptor
Q24561933Identification of different roles for RanGDP and RanGTP in nuclear protein import
Q74033395Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis
Q24319791Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells
Q48059143Importin provides a link between nuclear protein import and U snRNA export
Q77519042In vitro characterization of rice importin beta1: molecular interaction with nuclear transport factors and mediation of nuclear protein import
Q35293826In vivo biochemical analyses reveal distinct roles of β-importins and eEF1A in tRNA subcellular traffic
Q27935422Inactivation of the yeast Sen1 protein affects the localization of nucleolar proteins
Q36569133Interaction between the small GTPase Ran/Gsp1p and Ntf2p is required for nuclear transport
Q27937378Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase
Q29620080Isolation and characterization of RAT1: an essential gene of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA
Q36234509Isolation and characterization of Saccharomyces cerevisiae mRNA transport-defective (mtr) mutants
Q36337950Kinetochore capture and bi-orientation on the mitotic spindle.
Q27933781Location of N2, N2-dimethylguanosine-specific tRNA methyltransferase
Q36691103MOD5 translation initiation sites determine N6-isopentenyladenosine modification of mitochondrial and cytoplasmic tRNA
Q27939754Mechanism and a peptide motif for targeting peripheral proteins to the yeast inner nuclear membrane
Q24683718Molecular characterization of the SUMO-1 modification of RanGAP1 and its role in nuclear envelope association
Q24548343Monoclonal antibodies to NTF2 inhibit nuclear protein import by preventing nuclear translocation of the GTPase Ran
Q27932693Mutants in a yeast Ran binding protein are defective in nuclear transport
Q36556373Mutations altering the mitochondrial-cytoplasmic distribution of Mod5p implicate the actin cytoskeleton and mRNA 3' ends and/or protein synthesis in mitochondrial delivery
Q27937192Mutations in nucleolar proteins lead to nucleolar accumulation of polyA+ RNA in Saccharomyces cerevisiae
Q27934906NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viability
Q24533395NTF2 mediates nuclear import of Ran.
Q40365381NUP2, a novel yeast nucleoporin, has functional overlap with other proteins of the nuclear pore complex
Q24644057Npp106p, a Schizosaccharomyces pombe nucleoporin similar to Saccharomyces cerevisiae Nic96p, functionally interacts with Rae1p in mRNA export
Q39451343Nuclear import of IkappaBalpha is accomplished by a ran-independent transport pathway
Q24670107Nuclear import of the ran exchange factor, RCC1, is mediated by at least two distinct mechanisms
Q42244671Nuclear localization signals of varicella zoster virus ORF4.
Q27934023Nuclear mRNA accumulation causes nucleolar fragmentation in yeast mtr2 mutant
Q27939266Nuclear pore proteins are involved in the biogenesis of functional tRNA
Q34426767Nuclear protein import
Q34694942Nuclear protein transport
Q37383484Nuclear transport defects and nuclear envelope alterations are associated with mutation of the Saccharomyces cerevisiae NPL4 gene
Q36372013Nuclear transport is becoming crystal clear
Q44272650Nucleocytoplasmic transport and cell proliferation
Q36574246Nucleocytoplasmic transport of macromolecules
Q40403309Nucleocytoplasmic transport: factors and mechanisms
Q27934686Nucleus-associated pools of Rna1p, the Saccharomyces cerevisiae Ran/TC4 GTPse activating protein involved in nucleus/cytosol transit
Q80387771Perinuclear and nuclear envelope localizations of Arabidopsis Ran proteins
Q36563690Perturbations in the spi1p GTPase cycle of Schizosaccharomyces pombe through its GTPase-activating protein and guanine nucleotide exchange factor components result in similar phenotypic consequences
Q43594141Phosphorylation regulates the interaction between Gln3p and the nuclear import factor Srp1p
Q34363202Pre-mRNA processing factors are required for nuclear export
Q28238897Preferential modification of nuclear proteins by a novel ubiquitin-like molecule
Q33831922Probing a structural model of the nuclear pore complex channel through molecular dynamics
Q34384095Protein export from the nucleus
Q49485954Putative reaction intermediates in Crm1-mediated nuclear protein export
Q28301171RNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae
Q24685628Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export
Q24293261Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor
Q26822052Ran-dependent nuclear export mediators: a structural perspective
Q58077231RanBP1 is crucial for the release of RanGTP from importin β-related nuclear transport factors
Q24554148RanGTP-binding protein NXT1 facilitates nuclear export of different classes of RNA in vitro
Q30304667Random mutagenesis and functional analysis of the Ran-binding protein, RanBP1.
Q30309361Regulation of nuclear import and export by the GTPase Ran.
Q47138357Release of condensin from mitotic chromosomes requires the Ran-GTP gradient in the reorganized nucleus
Q27939372Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import
Q27930653Role of nuclear pools of aminoacyl-tRNA synthetases in tRNA nuclear export
Q34340040Roles of cytoskeletal and junctional plaque proteins in nuclear signaling
Q36817251SRN1, a yeast gene involved in RNA processing, is identical to HEX2/REG1, a negative regulator in glucose repression
Q27936940STP1, a gene involved in pre-tRNA processing, encodes a nuclear protein containing zinc finger motifs
Q27930639Saccharomyces cerevisiae Mod5p-II contains sequences antagonistic for nuclear and cytosolic locations.
Q31814825Samp1, a RanGTP binding transmembrane protein in the inner nuclear membrane
Q24652656Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing
Q34166891Separate responses of karyopherins to glucose and amino acid availability regulate nucleocytoplasmic transport
Q37163028Spatial and temporal coordination of mitosis by Ran GTPase
Q73066306Structural and functional diversity in the leucine-rich repeat family of proteins
Q42603621Subcellular locations of MOD5 proteins: mapping of sequences sufficient for targeting to mitochondria and demonstration that mitochondrial and nuclear isoforms commingle in the cytosol
Q27934539TPD1 of Saccharomyces cerevisiae encodes a protein phosphatase 2C-like activity implicated in tRNA splicing and cell separation
Q50715683Terminal minihelix, a novel RNA motif that directs polymerase III transcripts to the cell cytoplasm. Terminal minihelix and RNA export
Q27934083The REG2 gene of Saccharomyces cerevisiae encodes a type 1 protein phosphatase-binding protein that functions with Reg1p and the Snf1 protein kinase to regulate growth
Q27935668The acidic C-terminal domain of rna1p is required for the binding of Ran.GTP and for RanGAP activity.
Q29616325The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus
Q52111203The auto-inhibitory function of importin alpha is essential in vivo.
Q72153327The glucose repression and RAS-cAMP signal transduction pathways of Saccharomyces cerevisiae each affect RNA processing and the synthesis of a reporter protein
Q28254641The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export
Q34739115The interaction between Ran and NTF2 is required for cell cycle progression
Q28144428The mammalian Mog1 protein is a guanine nucleotide release factor for Ran
Q27930086The mechanism of ran import into the nucleus by nuclear transport factor 2.
Q38044350The molecular architecture of the plant nuclear pore complex.
Q38360627The nuclear transport factor karyopherin beta binds stoichiometrically to Ran-GTP and inhibits the Ran GTPase activating protein
Q79280658The plant nuclear envelope
Q27935486The product of the Saccharomyces cerevisiae RSS1 gene, identified as a high-copy suppressor of the rat7-1 temperature-sensitive allele of the RAT7/NUP159 nucleoporin, is required for efficient mRNA export
Q68149908The yeast RNA1 protein, necessary for RNA processing, is homologous to the human ribonuclease/angiogenin inhibitor (RAI)
Q34467663Transport into and out of the cell nucleus
Q29615611Transport into and out of the nucleus
Q34066757Transport of macromolecules between the nucleus and the cytoplasm
Q33345724Two distinct interacting classes of nuclear envelope-associated coiled-coil proteins are required for the tissue-specific nuclear envelope targeting of Arabidopsis RanGAP.
Q27937486Ultrastructural localization of rRNA shows defective nuclear export of preribosomes in mutants of the Nup82p complex.
Q27936568Yeast Ran-binding protein 1 (Yrb1) shuttles between the nucleus and cytoplasm and is exported from the nucleus via a CRM1 (XPO1)-dependent pathway
Q27929950Yrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue
Q27933997Yrb2p, a Nup2p-related yeast protein, has a functional overlap with Rna1p, a yeast Ran-GTPase-activating protein
Q37614220mRNA leader length and initiation codon context determine alternative AUG selection for the yeast gene MOD5.
Q40672468mRNA nuclear export
Q34447643mRNA transport in yeast: time to reinvestigate the functions of the nucleolus.
Q27936231nup1 mutants exhibit pleiotropic defects in nuclear pore complex function

Search more.