| scholarly article | Q13442814 |
| P50 | author | Stephen P Jackson | Q37392575 |
| Sophie E Polo | Q50199081 | ||
| P2093 | author name string | Gaëlle Legube | |
| Julia Coates | |||
| Sébastien Britton | |||
| Kyle M Miller | |||
| Jorrit V Tjeertes | |||
| P2860 | cites work | Negative control of p53 by Sir2alpha promotes cell survival under stress | Q24291828 |
| RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins | Q24300411 | ||
| RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly | Q24300428 | ||
| The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage | Q24309181 | ||
| RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins | Q24309287 | ||
| Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a | Q24324559 | ||
| DNA resection in eukaryotes: deciding how to fix the break | Q24603592 | ||
| The DNA-damage response in human biology and disease | Q24606586 | ||
| Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks | Q24608599 | ||
| Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase | Q24653776 | ||
| CBP/p300-mediated acetylation of histone H3 on lysine 56 | Q24657910 | ||
| Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4 | Q24675041 | ||
| The role of chromatin during transcription | Q27860995 | ||
| Chromatin modifications and their function | Q27861067 | ||
| Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair. | Q27935926 | ||
| Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair | Q27940284 | ||
| Repair of and checkpoint response to topoisomerase I-mediated DNA damage | Q28187875 | ||
| Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer | Q28239595 | ||
| Histone deacetylases and cancer | Q28240447 | ||
| Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes | Q28255974 | ||
| The DNA damage response: ten years after | Q28261230 | ||
| Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks | Q28286203 | ||
| Immunolocalization of Ku-proteins (p80/p70): localization of p70 to nucleoli and periphery of both interphase nuclei and metaphase chromosomes | Q28574093 | ||
| The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen | Q28608938 | ||
| Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions | Q29614216 | ||
| DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis | Q29614217 | ||
| Mammalian sirtuins: biological insights and disease relevance | Q29614496 | ||
| GammaH2AX and cancer | Q29614974 | ||
| A DNA damage checkpoint response in telomere-initiated senescence | Q29615919 | ||
| Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints | Q29617405 | ||
| Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication | Q29617915 | ||
| The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men | Q29619117 | ||
| Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice | Q29619786 | ||
| Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks | Q33282240 | ||
| Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation | Q33929178 | ||
| ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin | Q34801409 | ||
| The emerging role of nuclear architecture in DNA repair and genome maintenance | Q36340722 | ||
| gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes | Q36418967 | ||
| Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia | Q36585497 | ||
| Chromatin challenges during DNA replication and repair | Q36744476 | ||
| Histone deacetylase inhibitors: signalling towards p21cip1/waf1. | Q36782509 | ||
| Chromatin dynamics and the preservation of genetic information | Q36854289 | ||
| Inhibition of histone deacetylation: a strategy for tumor radiosensitization | Q36935075 | ||
| What histone code for DNA repair? | Q37093152 | ||
| Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. | Q37164089 | ||
| Living on a break: cellular senescence as a DNA-damage response | Q37198572 | ||
| Histone deacetylase inhibitors: anticancer compounds | Q37290570 | ||
| Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining | Q37365625 | ||
| Role of HDAC1 in senescence, aging, and cancer | Q37612283 | ||
| High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome. | Q39719766 | ||
| Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6. | Q39821961 | ||
| A histone code for the DNA damage response in mammalian cells? | Q39827246 | ||
| Histone H3-K56 acetylation is important for genomic stability in mammals | Q39857418 | ||
| Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells | Q39858162 | ||
| The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability | Q43068161 | ||
| Regulation of histone H3 lysine 56 acetylation in Schizosaccharomyces pombe | Q43852300 | ||
| Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes. | Q44203824 | ||
| Taking it off: regulation of H3 K56 acetylation by Hst3 and Hst4. | Q46685536 | ||
| Loading of the nonhomologous end joining factor, Ku, on protein-occluded DNA ends | Q64388104 | ||
| Sensing of ionizing radiation-induced DNA damage by ATM through interaction with histone deacetylase | Q73107002 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | DNA damage | Q5205747 |
| P304 | page(s) | 1144-1151 | |
| P577 | publication date | 2010-08-29 | |
| P1433 | published in | Nature Structural & Molecular Biology | Q1071739 |
| P1476 | title | Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining | |
| P478 | volume | 17 |
| Q34614252 | 14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage |
| Q35483796 | A DNA/HDAC dual-targeting drug CY190602 with significantly enhanced anticancer potency |
| Q37040116 | A Role for Nuclear Actin in HDAC 1 and 2 Regulation |
| Q34132182 | A macrohistone variant links dynamic chromatin compaction to BRCA1-dependent genome maintenance. |
| Q34880219 | A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair |
| Q34270749 | A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure |
| Q21144893 | A role for the malignant brain tumour (MBT) domain protein LIN-61 in DNA double-strand break repair by homologous recombination |
| Q64259085 | A role of the 53BP1 protein in genome protection: structural and functional characteristics of 53BP1-dependent DNA repair |
| Q38712941 | A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog. |
| Q34303731 | APETALA2 negatively regulates multiple floral organ identity genes in Arabidopsis by recruiting the co-repressor TOPLESS and the histone deacetylase HDA19. |
| Q35259213 | ASF1A and ATM regulate H3K56-mediated cell-cycle checkpoint recovery in response to UV irradiation |
| Q64386695 | Accumulation of Ku70 at DNA double-strand breaks in living epithelial cells |
| Q28076086 | Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer |
| Q90255768 | Acetylation blocks DNA damage-induced chromatin ADP-ribosylation |
| Q27676128 | Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination |
| Q34713712 | Activation of DNA damage response signaling by condensed chromatin |
| Q37598459 | All roads lead to chromatin: Multiple pathways for histone deposition |
| Q64137700 | Alterations in histone acetylation following exposure to Co γ-rays and their relationship with chromosome damage in human lymphoblastoid cells |
| Q40541541 | An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair |
| Q38630610 | Analysis of human syndromes with disordered chromatin reveals the impact of heterochromatin on the efficacy of ATM-dependent G2/M checkpoint arrest. |
| Q40468248 | Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells. |
| Q53681442 | Bromodomain proteins: repairing DNA damage within chromatin. |
| Q47362873 | CDYL1 fosters double-strand break-induced transcription silencing and promotes homology-directed repair |
| Q102058918 | CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks |
| Q37899757 | Cancer cells' epigenetic composition and predisposition to histone deacetylase inhibitor sensitization |
| Q35896405 | Cells and Stripes: A novel quantitative photo-manipulation technique |
| Q37904144 | Chromatin and the DNA damage response: the cancer connection. |
| Q38068091 | Chromatin and the genome integrity network. |
| Q36012981 | Chromatin dynamics in DNA double-strand break repair |
| Q38253643 | Chromatin modifications and DNA repair: beyond double-strand breaks |
| Q36550882 | Chromatin modifications and the DNA damage response to ionizing radiation. |
| Q37249162 | Chromatin modifications associated with DNA double-strand breaks repair as potential targets for neurological diseases |
| Q33606592 | Chromatin modifications during repair of environmental exposure-induced DNA damage: a potential mechanism for stable epigenetic alterations. |
| Q38240348 | Chromatin regulation of DNA damage repair and genome integrity in the central nervous system |
| Q37961878 | Chromatin response to DNA double-strand break damage |
| Q42376666 | Chromatin states responsible for the regulation of differentially expressed genes under 60Co~γ ray radiation in rice. |
| Q33907067 | Chromatin-regulating proteins as targets for cancer therapy |
| Q41220276 | Chromosome territory relocation during DNA repair requires nuclear myosin 1 recruitment to chromatin mediated by ϒ-H2AX signaling |
| Q89637388 | Chronic irradiation of human cells reduces histone levels and deregulates gene expression |
| Q37856648 | Chronic obstructive pulmonary disease and lung cancer: new molecular insights |
| Q37684600 | Cigarette smoke induces distinct histone modifications in lung cells: implications for the pathogenesis of COPD and lung cancer |
| Q38204487 | Class I HDACs Affect DNA Replication, Repair, and Chromatin Structure: Implications for Cancer Therapy |
| Q38743534 | Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest. |
| Q41872120 | Class I histone deacetylase inhibitors inhibit the retention of BRCA1 and 53BP1 at the site of DNA damage |
| Q57071316 | Comprehensive Mapping of Histone Modifications at DNA Double-Strand Breaks Deciphers Repair Pathway Chromatin Signatures |
| Q36655948 | Connecting chromatin modifying factors to DNA damage response |
| Q42123554 | Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells |
| Q96607407 | Convergence of therapy-induced senescence (TIS) and EMT in multistep carcinogenesis: current opinions and emerging perspectives |
| Q42907173 | Conversations between chromatin modifications and DNA double strand break repair: a commentary |
| Q95407636 | Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer |
| Q38230583 | DNA damage and its links to neurodegeneration |
| Q36538520 | DNA damage due to oxidative stress in Chronic Obstructive Pulmonary Disease (COPD) |
| Q48709568 | DNA damage in the oligodendrocyte lineage and its role in brain aging |
| Q37724792 | DNA damage response is hijacked by human papillomaviruses to complete their life cycle |
| Q34528005 | DNA double-strand break repair: a tale of pathway choices |
| Q33834990 | DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin |
| Q41568111 | DNA repair goes hip-hop: SMARCA and CHD chromatin remodellers join the break dance. |
| Q27853235 | DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer |
| Q41954597 | DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM). |
| Q33871913 | Damage site chromatin: open or closed? |
| Q34488874 | Damaged DNA-binding protein down-regulates epigenetic mark H3K56Ac through histone deacetylase 1 and 2. |
| Q36367732 | Deacetylation of H4-K16Ac and heterochromatin assembly in senescence |
| Q35774022 | Deficiency of H3K79 histone methyltransferase Dot1-like protein (DOT1L) inhibits cell proliferation |
| Q36038071 | Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair |
| Q38083939 | Detection and repair of ionizing radiation-induced DNA double strand breaks: new developments in nonhomologous end joining |
| Q28257534 | Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells |
| Q33794146 | Direct evidence for cell adhesion-mediated radioresistance (CAM-RR) on the level of individual integrin β1 clusters. |
| Q35275846 | Direct involvement of retinoblastoma family proteins in DNA repair by non-homologous end-joining. |
| Q54259222 | Distinct Roles for Intestinal Epithelial Cell-Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal Homeostasis. |
| Q28283633 | Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function |
| Q38075987 | Double strand breaks: hurdles for RNA polymerase II transcription? |
| Q34391068 | Double-strand break repair: 53BP1 comes into focus |
| Q34045935 | Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4. |
| Q39046067 | Downregulation of histone deacetylase 1 by microRNA-520h contributes to the chemotherapeutic effect of doxorubicin |
| Q64389315 | Dynamic behavior of DNA topoisomerase IIβ in response to DNA double-strand breaks |
| Q24608343 | Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications |
| Q52843708 | Dynamics of plant histone modifications in response to DNA damage. |
| Q38406840 | Effects of soybean meal on digestive enzymes activity, expression of inflammation-related genes, and chromatin modifications in marine fish (Sparus aurata L.) larvae. |
| Q92405274 | Elevated HDAC activity and altered histone phospho-acetylation confer acquired radio-resistant phenotype to breast cancer cells |
| Q97527182 | Emerging Therapeutic Targets Against Toxoplasma gondii: Update on DNA Repair Response Inhibitors and Genotoxic Drugs |
| Q35975127 | Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy |
| Q60907794 | Epigenetic Targeting of Autophagy via HDAC Inhibition in Tumor Cells: Role of p53 |
| Q33554228 | Epigenetic control of mobile DNA as an interface between experience and genome change |
| Q37855747 | Epigenetic programming: from gametes to blastocyst |
| Q37976267 | Epigenetic regulation of genomic integrity |
| Q93387006 | Epigenomic drivers of immune dysfunction in aging |
| Q34110326 | Essential factors for incompatible DNA end joining at chromosomal DNA double strand breaks in vivo |
| Q40133479 | Estimation of low-dose radiation-responsive proteins in the absence of genomic instability in normal human fibroblast cells. |
| Q28550025 | Exploration of Novel Inhibitors for Class I Histone Deacetylase Isoforms by QSAR Modeling and Molecular Dynamics Simulation Assays |
| Q34603552 | Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs. |
| Q39150008 | Function of heterochromatin protein 1 during DNA repair |
| Q34305789 | Functions of FUS/TLS from DNA repair to stress response: implications for ALS. |
| Q28831346 | G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status |
| Q90707056 | GLP-catalyzed H4K16me1 promotes 53BP1 recruitment to permit DNA damage repair and cell survival |
| Q52720696 | Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema. |
| Q48020408 | Genome-wide survey and phylogenetic analysis of histone acetyltransferases and histone deacetylases of Plasmodium falciparum |
| Q96022929 | H3K36 dimethylation by MMSET promotes classical non-homologous end-joining at unprotected telomeres |
| Q38058971 | HDAC inhibitor-based therapies: can we interpret the code? |
| Q37962333 | HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications |
| Q92322678 | HDAC-dependent decrease in histone crotonylation during DNA damage |
| Q64105197 | HDAC1 and HDAC2 independently regulate common and specific intrinsic responses in murine enteroids |
| Q50317222 | HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130. |
| Q95328270 | HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease |
| Q53575196 | HDAC1 overexpression independently predicts biochemical recurrence and is associated with rapid tumor cell proliferation and genomic instability in prostate cancer. |
| Q38918235 | HDAC1,2 inhibition impairs EZH2- and BBAP-mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma |
| Q39211999 | HDAC1-mSin3a-NCOR1, Dnmt3b-HDAC1-Egr1 and Dnmt1-PCNA-UHRF1-G9a regulate the NY-ESO1 gene expression. |
| Q33733042 | HDAC2 overexpression correlates with aggressive clinicopathological features and DNA-damage response pathway of breast cancer |
| Q48233598 | HDAC2 selectively regulates FOXO3a-mediated gene transcription during oxidative stress-induced neuronal cell death |
| Q38947405 | HDACs and HDAC Inhibitors in Cancer Development and Therapy |
| Q64914446 | Harnessing the HDAC-histone deacetylase enzymes, inhibitors and how these can be utilised in tissue engineering. |
| Q98952077 | Heterochromatin: an epigenetic point of view in aging |
| Q89458299 | Histone H1 acetylation at lysine 85 regulates chromatin condensation and genome stability upon DNA damage |
| Q24612284 | Histone H3 lysine 56 acetylation and the response to DNA replication fork damage |
| Q58609638 | Histone Modifications and the DNA Double-Strand Break Response |
| Q53276828 | Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors. |
| Q33919809 | Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells |
| Q37331641 | Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice |
| Q30356611 | Histone deacetylase 10 regulates DNA mismatch repair and may involve the deacetylation of MutS homolog 2. |
| Q37665547 | Histone deacetylase 2 in the mouse hippocampus: attenuation of age-related increase by caloric restriction |
| Q36187806 | Histone deacetylase complexes as caretakers of genome stability. |
| Q33983255 | Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights |
| Q35006481 | Histone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells |
| Q34221822 | Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells |
| Q37929048 | Histone deacetylase inhibitor: antineoplastic agent and radiation modulator |
| Q26863429 | Histone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repair |
| Q37223734 | Histone deacetylase inhibitors decrease NHEJ both by acetylation of repair factors and trapping of PARP1 at DNA double-strand breaks in chromatin |
| Q92612020 | Histone deacetylase inhibitors dysregulate DNA repair proteins and antagonize metastasis-associated processes |
| Q35667942 | Histone deacetylase inhibitors globally enhance h3/h4 tail acetylation without affecting h3 lysine 56 acetylation |
| Q34416994 | Histone deacetylase inhibitors in the treatment of hematological malignancies and solid tumors |
| Q35592607 | Histone deacetylase inhibitors: emerging mechanisms of resistance. |
| Q100378830 | Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice |
| Q37291739 | Histone deacetylase regulation of ATM-mediated DNA damage signaling |
| Q37701599 | Histone deacetylases 1 and 2 cooperate in regulating BRCA1, CHK1, and RAD51 expression in acute myeloid leukemia cells |
| Q41772663 | Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression |
| Q38459887 | Histone deacetylases 1 and 2 regulate DNA replication and DNA repair: potential targets for genome stability-mechanism-based therapeutics for a subset of cancers |
| Q34624058 | Histone deacetylases 9 and 10 are required for homologous recombination |
| Q47826961 | Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair. |
| Q33627079 | Histone demethylase KDM5B is a key regulator of genome stability |
| Q37995722 | Histone marks: repairing DNA breaks within the context of chromatin |
| Q92505940 | Histone methylation and the DNA damage response |
| Q55261726 | Histone methylation in DNA repair and clinical practice: new findings during the past 5-years. |
| Q34045830 | Histone modifications and DNA double-strand break repair after exposure to ionizing radiations |
| Q38716430 | Histone modifications in DNA damage response |
| Q42153124 | Histone modifications in senescence-associated resistance to apoptosis by oxidative stress |
| Q37868421 | Histone onco-modifications |
| Q27003952 | Histone-modifying enzymes, histone modifications and histone chaperones in nucleosome assembly: Lessons learned from Rtt109 histone acetyltransferases |
| Q47217424 | Human CRL4DDB2 ubiquitin ligase preferentially regulates post-repair chromatin restoration of H3K56Ac through recruitment of histone chaperon CAF-1. |
| Q30666883 | IL-1α is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity |
| Q35658623 | Identification of small molecules that inhibit the histone chaperone Asf1 and its chromatin function |
| Q50091965 | Image-based drug screen identifies HDAC inhibitors as novel Golgi disruptors synergizing with JQ1. |
| Q36054138 | Impact of the DNA Damage Response on Human Papillomavirus Chromatin |
| Q42142886 | Impaired coenzyme A synthesis in fission yeast causes defective mitosis, quiescence-exit failure, histone hypoacetylation and fragile DNA. |
| Q31155069 | Inference of Candidate Germline Mutator Loci in Humans from Genome-Wide Haplotype Data |
| Q38973133 | Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease. |
| Q51757810 | Inhibition of histone deacetylases sensitizes glioblastoma cells to lomustine. |
| Q42835134 | Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells |
| Q41851979 | Inhibitors of histone deacetylases enhance neurotoxicity of DNA damage |
| Q36003205 | Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining |
| Q41469956 | Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons. |
| Q38984578 | Investigational histone deacetylase inhibitors (HDACi) in myeloproliferative neoplasms |
| Q40615400 | Isolation of chromatin from dysfunctional telomeres reveals an important role for Ring1b in NHEJ-mediated chromosome fusions |
| Q42152404 | KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response. |
| Q35532757 | KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining Repair |
| Q39792755 | Kaposi's sarcoma-associated herpesvirus latency in endothelial and B cells activates gamma interferon-inducible protein 16-mediated inflammasomes. |
| Q35888916 | L- and D-lactate enhance DNA repair and modulate the resistance of cervical carcinoma cells to anticancer drugs via histone deacetylase inhibition and hydroxycarboxylic acid receptor 1 activation |
| Q37062105 | Lung cancer and its association with chronic obstructive pulmonary disease: update on nexus of epigenetics |
| Q51358936 | MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents. |
| Q90736683 | MORC2 regulates DNA damage response through a PARP1-dependent pathway |
| Q38261628 | MTA family of proteins in DNA damage response: mechanistic insights and potential applications |
| Q34030459 | Mammalian Ino80 mediates double-strand break repair through its role in DNA end strand resection |
| Q26749169 | Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis |
| Q26992212 | Metabolism, longevity and epigenetics |
| Q34247838 | Metastasis-associated protein 1/nucleosome remodeling and histone deacetylase complex in cancer |
| Q37707218 | Methamphetamine downregulates striatal glutamate receptors via diverse epigenetic mechanisms. |
| Q26829103 | Minireview: Conversing with chromatin: the language of nuclear receptors |
| Q35842531 | Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage |
| Q38968135 | Modulation of inflammation and disease tolerance by DNA damage response pathways |
| Q45713817 | Modulation of the Fanconi anemia pathway via chemically induced changes in chromatin structure |
| Q35348809 | Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatin |
| Q60301058 | Molecular and epigenetic regulatory mechanisms of normal stem cell radiosensitivity |
| Q40227388 | Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate |
| Q37942059 | More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance |
| Q37979639 | Multiple roles of class I HDACs in proliferation, differentiation, and development |
| Q30538837 | NBM-T-L-BMX-OS01, Semisynthesized from Osthole, Is a Novel Inhibitor of Histone Deacetylase and Enhances Learning and Memory in Rats |
| Q36280824 | Nanolesions induced by heavy ions in human tissues: Experimental and theoretical studies |
| Q38922310 | Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice |
| Q39231599 | New factors in mammalian DNA repair-the chromatin connection |
| Q26776102 | Non-Coding RNA: Sequence-Specific Guide for Chromatin Modification and DNA Damage Signaling |
| Q43448263 | Nuclear expression of histone deacetylases and their histone modifications predicts clinical outcome in colorectal cancer. |
| Q38743349 | Nucleolar Reorganization Upon Site-Specific Double-Strand Break Induction |
| Q35113119 | Nucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling. |
| Q38321688 | Oncogene Ras/phosphatidylinositol 3-kinase signaling targets histone H3 acetylation at lysine 56. |
| Q38043545 | Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases |
| Q97423269 | PAICS contributes to gastric carcinogenesis and participates in DNA damage response by interacting with histone deacetylase 1/2 |
| Q33635465 | PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways. |
| Q38655184 | Patching Broken DNA: Nucleosome Dynamics and the Repair of DNA Breaks |
| Q51737822 | Pharmacological or transcriptional inhibition of both HDAC1 and 2 leads to cell cycle blockage and apoptosis via p21Waf1/Cip1 and p19INK4d upregulation in hepatocellular carcinoma. |
| Q57295277 | Phosphorylation of TIP60 suppresses 53BP1 localization at DNA damage sites |
| Q39166811 | Possible involvement of LKB1-AMPK signaling in non-homologous end joining |
| Q52757724 | Preclinical evaluation and molecular docking of 1,3-benzodioxole propargyl ether derivatives as novel inhibitor for combating the histone deacetylase enzyme in cancer. |
| Q41908887 | Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection |
| Q39293918 | Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin |
| Q98778842 | Protein acetylation and deacetylation: An important regulatory modification in gene transcription (Review) |
| Q45807486 | Quantifying DNA double-strand breaks induced by site-specific endonucleases in living cells by ligation-mediated purification. |
| Q39040990 | Quantitation of DNA double-strand break resection intermediates in human cells. |
| Q40861699 | Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response. |
| Q36319273 | Quantitative structure-activity relationship analysis and virtual screening studies for identifying HDAC2 inhibitors from known HDAC bioactive chemical libraries |
| Q47177294 | RBM45 competes with HDAC1 for binding to FUS in response to DNA damage |
| Q21129305 | Radiation-induced alterations in histone modification patterns and their potential impact on short-term radiation effects |
| Q39035998 | Radiation-induced alterations of histone post-translational modification levels in lymphoblastoid cell lines |
| Q98735969 | Randomized phase II study of valproic acid in combination with bevacizumab and oxaliplatin/fluoropyrimidine regimens in patients with RAS-mutated metastatic colorectal cancer: the REVOLUTION study protocol |
| Q41874822 | Rapid and transient protein acetylation changes in response to DNA damage |
| Q35750491 | Rational Combinations of Targeted Agents in AML |
| Q50494189 | Reading chromatin signatures after DNA double-strand breaks. |
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