Histone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells

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Histone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/S12858-014-0030-5
P932PMC publication ID4304611
P698PubMed publication ID25592494
P5875ResearchGate publication ID270962008

P2093author name stringLi Ma
Pengfei Wu
Lijun Chen
Liping Li
Xiaodan Wu
Jiangqin Liu
Youxiang Sun
P2860cites workEffects of valproic acid in combination with S-1 on advanced pancreatobiliary tract cancers: clinical study phases I/IIQ57150032
Histone deacetylase inhibitor sodium butyrate enhances cellular radiosensitivity by inhibiting both DNA nonhomologous end joining and homologous recombinationQ84718317
Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombinationQ27676128
Downregulation of homologous recombination DNA repair genes by HDAC inhibition in prostate cancer is mediated through the E2F1 transcription factorQ28474504
Combination therapy with the histone deacetylase inhibitor LBH589 and radiation is an effective regimen for prostate cancer cells.Q31133958
Sodium butyrate enhances the cytotoxic effect of cisplatin by abrogating the cisplatin imposed cell cycle arrestQ33615259
The therapeutic potential of class I selective histone deacetylase inhibitors in ovarian cancerQ33659166
Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair.Q34093052
Erlotinib attenuates homologous recombinational repair of chromosomal breaks in human breast cancer cellsQ36982835
Genetic dissection of histone deacetylase requirement in tumor cellsQ37194816
Histone deacetylase regulation of ATM-mediated DNA damage signalingQ37291739
Inhibition of homologous recombination with vorinostat synergistically enhances ganciclovir cytotoxicity.Q37579567
Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: the molecular choreographyQ38022419
Histone deacetylase inhibitors disrupt the mitotic spindle assembly checkpoint by targeting histone and nonhistone proteinsQ38054218
Synergistic loss of prostate cancer cell viability by coinhibition of HDAC and PARP.Q38965645
HDAC inhibitors reverse acquired radio resistance of KYSE-150R esophageal carcinoma cells by modulating Bmi-1 expressionQ39031147
Low dose histone deacetylase inhibitor, LBH589, potentiates anticancer effect of docetaxel in epithelial ovarian cancer via PI3K/Akt pathway in vitroQ39275045
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joiningQ39662092
Enhancement of radiation response in osteosarcoma and rhabdomyosarcoma cell lines by histone deacetylase inhibitionQ39677848
Inhibition of histone deacetylase in cancer cells slows down replication forks, activates dormant origins, and induces DNA damageQ39705077
Scriptaid, a novel histone deacetylase inhibitor, enhances the response of human tumor cells to radiationQ39767757
In vivo synergy between topoisomerase II and histone deacetylase inhibitors: predictive correlatesQ40336852
Inhibitors of histone deacetylases enhance neurotoxicity of DNA damageQ41851979
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectetoposideQ418817
P304page(s)2
P577publication date2015-01-16
P1433published inBMC BiochemistryQ15765786
P1476titleHistone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells
P478volume16

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cites work (P2860)
Q47175684Histone deacetylase inhibitor NaBut suppresses cell proliferation and induces apoptosis by targeting p21 in multiple myeloma
Q40757101Involvement of 15-lipoxygenase-1 in the regulation of breast cancer cell death induced by sodium butyrate
Q50056574Potential anti-genotoxic effect of sodium butyrate to modulate induction of DNA damage by tamoxifen citrate in rat bone marrow cells
Q54959664Pushing the Limits of Cancer Therapy: The Nutrient Game.
Q46269927Sodium butyrate promotes apoptosis in breast cancer cells through reactive oxygen species (ROS) formation and mitochondrial impairment.
Q49544302Targeting the Epigenome as a Novel Therapeutic Approach for Breast Cancer
Q57105429The Histone Acetylation Modifications of Breast Cancer and their Therapeutic Implications
Q38979892The multifaceted influence of histone deacetylases on DNA damage signalling and DNA repair
Q42321289mTORC1 and -2 Coordinate Transcriptional and Translational Reprogramming in Resistance to DNA Damage and Replicative Stress in Breast Cancer Cells.

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