scholarly article | Q13442814 |
P50 | author | Andrew W Truman | Q61104160 |
Jacques Coté | Q42712452 | ||
Stephen J. Kron | Q43233339 | ||
P2093 | author name string | Dorine Rossetto | |
P2860 | cites work | New Histone Incorporation Marks Sites of UV Repair in Human Cells | Q63383593 |
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks | Q24299852 | ||
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins | Q24300411 | ||
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly | Q24300428 | ||
A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair | Q24302261 | ||
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites | Q24306789 | ||
WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity | Q24309061 | ||
Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression | Q24309909 | ||
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions | Q24313501 | ||
Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase | Q24320001 | ||
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks | Q24321489 | ||
BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response | Q24323889 | ||
Involvement of human MOF in ATM function | Q24529072 | ||
DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A | Q24546161 | ||
A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage | Q24554315 | ||
Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention | Q24563397 | ||
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks | Q24608599 | ||
A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication | Q24626425 | ||
Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56 | Q24633791 | ||
Histone H4 lysine 91 acetylation a core domain modification associated with chromatin assembly | Q24634725 | ||
Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction | Q38310324 | ||
High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome. | Q39719766 | ||
Cohesion establishment factor, Eco1 represses transcription via association with histone demethylase, LSD1. | Q39724160 | ||
Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition | Q39747969 | ||
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells | Q39858162 | ||
Local action of the chromatin assembly factor CAF-1 at sites of nucleotide excision repair in vivo | Q39927746 | ||
Histone acetyltransferase 1 is dispensable for replication-coupled chromatin assembly but contributes to recover DNA damages created following replication blockage in vertebrate cells | Q40273789 | ||
gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair | Q40347113 | ||
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions | Q40495236 | ||
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation | Q40570996 | ||
Cooperative control of Crb2 by ATM family and Cdc2 kinases is essential for the DNA damage checkpoint in fission yeast | Q40701887 | ||
RSC functions as an early double-strand-break sensor in the cell's response to DNA damage | Q41114918 | ||
Induction of CAF-1 expression in response to DNA strand breaks in quiescent human cells | Q41843208 | ||
Distinct targets of the Eco1 acetyltransferase modulate cohesion in S phase and in response to DNA damage | Q41852552 | ||
Dissection of Rad9 BRCT domain function in the mitotic checkpoint response to telomere uncapping | Q42091851 | ||
Histone H3-K56 acetylation is catalyzed by histone chaperone-dependent complexes | Q42850451 | ||
RSC mobilizes nucleosomes to improve accessibility of repair machinery to the damaged chromatin | Q42924860 | ||
Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair | Q43217577 | ||
Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae | Q43230977 | ||
Cell cycle and checkpoint regulation of histone H3 K56 acetylation by Hst3 and Hst4. | Q43796805 | ||
Phosphorylation of histone H4 serine 1 during DNA damage requires casein kinase II in S. cerevisiae | Q46432359 | ||
Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation | Q50731881 | ||
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase | Q24653776 | ||
CBP/p300-mediated acetylation of histone H3 on lysine 56 | Q24657910 | ||
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair | Q24669691 | ||
Megabase chromatin domains involved in DNA double-strand breaks in vivo | Q24680284 | ||
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics | Q24681614 | ||
A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin | Q24801790 | ||
The role of chromatin during transcription | Q27860995 | ||
ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex | Q27929959 | ||
A role for Saccharomyces cerevisiae histone H2A in DNA repair. | Q27930827 | ||
Eaf1 is the platform for NuA4 molecular assembly that evolutionarily links chromatin acetylation to ATP-dependent exchange of histone H2A variants | Q27931128 | ||
Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4. | Q27931428 | ||
Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites | Q27931488 | ||
Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair | Q27933564 | ||
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery | Q27933727 | ||
INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. | Q27933934 | ||
Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks. | Q27934708 | ||
The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks | Q27934796 | ||
Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication | Q27935707 | ||
Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair. | Q27935926 | ||
NuA4-dependent acetylation of nucleosomal histones H4 and H2A directly stimulates incorporation of H2A.Z by the SWR1 complex. | Q27936275 | ||
DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain | Q27937364 | ||
The sirtuins hst3 and Hst4p preserve genome integrity by controlling histone h3 lysine 56 deacetylation. | Q27937957 | ||
Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4 | Q27938208 | ||
Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling | Q27938440 | ||
Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9. | Q27939003 | ||
Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair | Q27940284 | ||
PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint | Q28117742 | ||
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 | Q28131715 | ||
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage | Q28144576 | ||
Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress | Q28201846 | ||
Endogenous DNA damage in humans: a review of quantitative data | Q28259993 | ||
A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM | Q28270543 | ||
Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks | Q28286203 | ||
Phosphorylation of histone H2B at DNA double-strand breaks. | Q36402644 | ||
Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control | Q36639688 | ||
Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage | Q36696336 | ||
Histone modifications in response to DNA damage. | Q36738568 | ||
Chromatin assembly factors Asf1 and CAF-1 have overlapping roles in deactivating the DNA damage checkpoint when DNA repair is complete | Q37078952 | ||
Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin. | Q37347174 | ||
gammaH2AX: a sensitive molecular marker of DNA damage and repair | Q37687078 | ||
Chaperoning histones during DNA replication and repair | Q37689255 | ||
"Contextual" synthetic lethality and/or loss of heterozygosity: tumor hypoxia and modification of DNA repair. | Q37786125 | ||
Perspective on the Pipeline of Drugs Being Developed with Modulation of DNA Damage as a Target | Q37786126 | ||
The epigenomics of cancer | Q28289975 | ||
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals | Q28292900 | ||
Genomic instability in mice lacking histone H2AX | Q28589826 | ||
Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage | Q29614528 | ||
Cancer epigenomics: DNA methylomes and histone-modification maps | Q29615524 | ||
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks | Q29617463 | ||
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map | Q29618911 | ||
Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair | Q29620305 | ||
Human Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage | Q30441323 | ||
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks | Q30480374 | ||
Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinated H2A at damaged genomic sites | Q30854865 | ||
Insights into the role of histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiae | Q33226323 | ||
gammaH2AX foci form preferentially in euchromatin after ionising-radiation. | Q33303665 | ||
Chromosome-wide Rad51 spreading and SUMO-H2A.Z-dependent chromosome fixation in response to a persistent DNA double-strand break | Q33409251 | ||
DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression | Q33537400 | ||
Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX. | Q33705076 | ||
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair | Q33963853 | ||
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX | Q34031720 | ||
Histone γH2AX and Poly(ADP-Ribose) as Clinical Pharmacodynamic Biomarkers | Q34134483 | ||
The diverse functions of histone acetyltransferase complexes. | Q34205129 | ||
Histone H3 and the histone acetyltransferase Hat1p contribute to DNA double-strand break repair | Q34286591 | ||
Poly (ADP-ribose) polymerase as a novel therapeutic target in cancer | Q34308770 | ||
Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break | Q34354650 | ||
Localized histone acetylation and deacetylation triggered by the homologous recombination pathway of double-strand DNA repair. | Q34422309 | ||
A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response. | Q34433751 | ||
Activation and regulation of ATM kinase activity in response to DNA double-strand breaks | Q34722727 | ||
Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX. | Q34841266 | ||
Crosstalk between histone modifications during the DNA damage response. | Q34973824 | ||
Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response | Q35006034 | ||
Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage. | Q35018049 | ||
Cellular machineries for chromosomal DNA repair. | Q35742332 | ||
Contribution of the serine 129 of histone H2A to chromatin structure | Q35856903 | ||
New anti-cancer strategies: epigenetic therapies and biomarkers | Q36071790 | ||
Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals | Q36118803 | ||
Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair | Q36159147 | ||
P433 | issue | 18 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | DNA damage | Q5205747 |
P304 | page(s) | 4543-4552 | |
P577 | publication date | 2010-09-07 | |
P1433 | published in | Clinical Cancer Research | Q332253 |
P1476 | title | Epigenetic modifications in double-strand break DNA damage signaling and repair | |
P478 | volume | 16 |
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