scholarly article | Q13442814 |
P50 | author | Judy Lieberman | Q89574003 |
P2093 | author name string | Dipanjan Chowdhury | |
Craig L Peterson | |||
Michael-Christopher Keogh | |||
Stephen Buratowski | |||
Haruhiko Ishii | |||
P433 | issue | 5 | |
P304 | page(s) | 801-809 | |
P577 | publication date | 2005-11-28 | |
P1433 | published in | Molecular Cell | Q3319468 |
P1476 | title | gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair | |
P478 | volume | 20 |
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Q24299264 | A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination |
Q24626425 | A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication |
Q48104450 | A Role for the Twins Protein Phosphatase (PP2A-B55) in the Maintenance of Drosophila Genome Integrity |
Q33489221 | A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability |
Q37350638 | A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair |
Q24682800 | A novel histone exchange factor, protein phosphatase 2Cgamma, mediates the exchange and dephosphorylation of H2A-H2B |
Q36016499 | A p53 axis regulates B cell receptor-triggered, innate immune system-driven B cell clonal expansion |
Q27933727 | A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery |
Q41198504 | A phosphorylation switch regulates the transcriptional activation of cell cycle regulator p21 by histone deacetylase inhibitors. |
Q42262923 | A specific inhibitor of protein kinase CK2 delays gamma-H2Ax foci removal and reduces clonogenic survival of irradiated mammalian cells |
Q35259213 | ASF1A and ATM regulate H3K56-mediated cell-cycle checkpoint recovery in response to UV irradiation |
Q35946391 | ASY1 mediates AtDMC1-dependent interhomolog recombination during meiosis in Arabidopsis. |
Q35865561 | ATP-dependent chromatin remodeling factors and DNA damage repair |
Q38862365 | Absolute quantification of acetylation and phosphorylation of the histone variant H2AX upon ionizing radiation reveals distinct cellular responses in two cancer cell lines |
Q28593756 | Alpha4 is an essential regulator of PP2A phosphatase activity |
Q37121891 | An engineered bivalent neuregulin protects against doxorubicin-induced cardiotoxicity with reduced proneoplastic potential. |
Q33948911 | Analysis of individual molecular events of DNA damage response by flow- and image-assisted cytometry |
Q36065662 | Association of ATM activation and DNA repair with induced radioresistance after low-dose irradiation |
Q37802011 | At the stem of youth and health |
Q38610354 | Ataxia telangiectasia-mutated damage-signaling kinase- and proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in Simian virus 40-infected primate cells |
Q33589397 | Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway |
Q37875377 | Beyond ATM: the protein kinase landscape of the DNA damage response |
Q39003035 | Biological effects of (125)i seeds radiation on A549 lung cancer cells: G2/M arrest and enhanced cell death |
Q35597445 | Calibration of the γ-H2AX DNA double strand break focus assay for internal radiation exposure of blood lymphocytes |
Q92636595 | Cell Cycle and DNA Repair Regulation in the Damage Response: Protein Phosphatases Take Over the Reins |
Q37628726 | Cell signalling and radiation survival: the impact of protein phosphatases |
Q52723382 | Cell-line dependent effects of hypoxia prior to irradiation in squamous cell carcinoma lines. |
Q36447371 | Cellular defects caused by hypomorphic variants of the Bloom syndrome helicase gene BLM. |
Q37600456 | Chapter 6. Application of new methods for detection of DNA damage and repair |
Q45925903 | Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage. |
Q37941374 | Checkpoint control and cancer. |
Q38068091 | Chromatin and the genome integrity network. |
Q33729186 | Chromatin at the intersection of viral infection and DNA damage |
Q37760043 | Chromatin dynamics during repair of chromosomal DNA double-strand breaks |
Q36676071 | Chromatin modifications and DNA double-strand breaks: the current state of play |
Q38253643 | Chromatin modifications and DNA repair: beyond double-strand breaks |
Q36558897 | Chromatin modulation and the DNA damage response |
Q37321372 | Chromatin recruitment of DNA repair proteins: lessons from the fanconi anemia and double-strand break repair pathways. |
Q36660520 | Chromatin remodeling and repair of DNA double-strand breaks |
Q37128128 | Chromatin remodeling finds its place in the DNA double-strand break response |
Q37961878 | Chromatin response to DNA double-strand break damage |
Q40868345 | Chromosome territories reposition during DNA damage-repair response |
Q34140001 | Cohesin protects genes against γH2AX Induced by DNA double-strand breaks |
Q37398600 | Connection between histone H2A variants and chromatin remodeling complexes |
Q35856903 | Contribution of the serine 129 of histone H2A to chromatin structure |
Q28251838 | Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers |
Q27310439 | Cyclin G Functions as a Positive Regulator of Growth and Metabolism in Drosophila |
Q33290461 | Cytometry of ATM activation and histone H2AX phosphorylation to estimate extent of DNA damage induced by exogenous agents |
Q33873505 | DNA cross-linking, double-strand breaks, and apoptosis in corneal endothelial cells after a single exposure to mitomycin C. |
Q38405830 | DNA damage checkpoint recovery and cancer development |
Q64387140 | DNA damage in blood leucocytes of prostate cancer patients during therapy with Lu-PSMA |
Q36011116 | DNA damage in blood lymphocytes in patients after (177)Lu peptide receptor radionuclide therapy. |
Q48042018 | DNA damage in leukocytes after internal ex-vivo irradiation of blood with the α-emitter Ra-223. |
Q28393323 | DNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometry |
Q26822413 | DNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosis |
Q35381608 | DNA damage: a sensible mediator of the differentiation decision in hematopoietic stem cells and in leukemia. |
Q34360500 | DNA double-strand break signaling and human disorders |
Q80008501 | DNA profiling analysis of 100 consecutive de novo acute myeloid leukemia cases reveals patterns of genomic instability that affect all cytogenetic risk groups |
Q33537400 | DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression |
Q64091697 | Delayed γH2AX foci disappearance in mammary epithelial cells from aged women reveals an age-associated DNA repair defect |
Q24313879 | Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent |
Q37698587 | Dephosphorylation of γ-H2AX by WIP1: an important homeostatic regulatory event in DNA repair and cell cycle control |
Q38023415 | Design stars: how small DNA viruses remodel the host nucleus |
Q30431944 | Destabilization of TIP60 by human papillomavirus E6 results in attenuation of TIP60-dependent transcriptional regulation and apoptotic pathway |
Q41780852 | Differences in Phosphorylated Histone H2AX Foci Formation and Removal of Cells Exposed to Low and High Linear Energy Transfer Radiation. |
Q39148112 | Differential effect of hypoxia on etoposide-induced DNA damage response and p53 regulation in different cell types |
Q47146141 | Digoxin enhances radiation response in radioresistant A549 cells by reducing protein phosphatase 2A. |
Q55512207 | Double Strand Break DNA Repair occurs via Non-Homologous End-Joining in Mouse MII Oocytes. |
Q37822707 | Double-strand breaks and the concept of short- and long-term epigenetic memory. |
Q24608343 | Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications |
Q92596472 | Effect of the Large and Small T-Antigens of Human Polyomaviruses on Signaling Pathways |
Q36743535 | Emerging roles of nuclear protein phosphatases |
Q28749982 | Epigenetic mechanisms in mammals |
Q24607287 | Epigenetic modifications in double-strand break DNA damage signaling and repair |
Q64260686 | Escherichia Coli Outer Membrane Vesicles Induced DNA Double-Strand Breaks in Intestinal Epithelial Caco-2 Cells |
Q60048083 | Evaluating Gamma-H2AX Expression as a Biomarker of DNA Damage after X-ray in Angiography Patients |
Q39893311 | Explanation for excessive DNA single-strand breaks and endogenous repair foci in pluripotent mouse embryonic stem cells |
Q41842719 | Expression and regulation of type 2A protein phosphatases and alpha4 signalling in cardiac health and hypertrophy |
Q36579359 | Five repair pathways in one context: chromatin modification during DNA repair |
Q36963162 | Focus on histone variant H2AX: to be or not to be. |
Q37347174 | Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin. |
Q37261069 | Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin |
Q36148914 | Gamma-H2AX upregulation caused by Wip1 deficiency increases depression-related cellular senescence in hippocampus |
Q29614974 | GammaH2AX and cancer |
Q36579390 | GammaH2AX and its role in DNA double-strand break repair |
Q40042252 | Genetic variants in PPP2CA are associated with gastric cancer risk in a Chinese population |
Q41660493 | Genome Instability and γH2AX. |
Q80731900 | Genome scan implicates adhesion biological pathways in secondary leukemia |
Q92477508 | Genomic Integrity Safeguards Self-Renewal in Embryonic Stem Cells |
Q94686254 | Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response |
Q35132069 | H2AX chromatin structures and their response to DNA damage revealed by 4Pi microscopy |
Q36001923 | H2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues |
Q33847860 | H2AX phosphorylation screen of cells from radiosensitive cancer patients reveals a novel DNA double-strand break repair cellular phenotype |
Q82452820 | HSP72 depletion suppresses gammaH2AX activation by genotoxic stresses via p53/p21 signaling |
Q40068992 | Hepatitis C virus NS3/4A protein interacts with ATM, impairs DNA repair and enhances sensitivity to ionizing radiation. |
Q42830844 | Hepatitis C virus-induced up-regulation of protein phosphatase 2A inhibits histone modification and DNA damage repair |
Q37843473 | Heterochromatin and the DNA damage response: the need to relax |
Q58609638 | Histone Modifications and the DNA Double-Strand Break Response |
Q34121643 | Histone XH2AX is required for Xenopus anterior neural development: critical role of threonine 16 phosphorylation. |
Q36994149 | Histone chaperones: an escort network regulating histone traffic |
Q38716430 | Histone modifications in DNA damage response |
Q34297533 | Histone phosphorylation: a chromatin modification involved in diverse nuclear events |
Q38208178 | Histone variants: key players of chromatin |
Q38355887 | Histone variants: the artists of eukaryotic chromatin |
Q34134483 | Histone γH2AX and Poly(ADP-Ribose) as Clinical Pharmacodynamic Biomarkers |
Q38903158 | Human JC virus small tumour antigen inhibits nucleotide excision repair and sensitises cells to DNA-damaging agents. |
Q30441323 | Human Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage |
Q40199767 | Human cytomegalovirus disrupts both ataxia telangiectasia mutated protein (ATM)- and ATM-Rad3-related kinase-mediated DNA damage responses during lytic infection |
Q21091196 | Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response |
Q47135345 | IER5 is involved in DNA Double-Strand Breaks Repair in Association with PAPR1 in Hela Cells |
Q35472154 | Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1. |
Q34428739 | Increased γ-H2A.X intensity in response to chronic medium-dose-rate γ-ray irradiation |
Q34121601 | Induction and repair of DNA double-strand breaks assessed by gamma-H2AX foci after irradiation with pulsed or continuous proton beams. |
Q34777845 | Inhibition of protein phosphatase 2A radiosensitizes pancreatic cancers by modulating CDC25C/CDK1 and homologous recombination repair |
Q34365755 | Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair |
Q36003205 | Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining |
Q64883630 | Integrating the DNA damage and protein stress responses during cancer development and treatment. |
Q37500155 | Interaction between viral proteins and hosts and its disturbance in the cellular responses to ionising radiation |
Q37797693 | Interplay Between Different Epigenetic Modifications and Mechanisms |
Q30032667 | Involvement of GLTSCR2 in the DNA Damage Response |
Q36579347 | Is histone loss a common feature of DNA metabolism regulation? |
Q59346828 | LNT: a never-ending story |
Q39505755 | Leucine Carboxyl Methyltransferase 1 (LCMT-1) Methylates Protein Phosphatase 4 (PP4) and Protein Phosphatase 6 (PP6) and Differentially Regulates the Stable Formation of Different PP4 Holoenzymes |
Q52981183 | Lipoic acid induces p53-independent cell death in colorectal cancer cells and potentiates the cytotoxicity of 5-fluorouracil. |
Q34288868 | Loss of CCDC6, the first identified RET partner gene, affects pH2AX S139 levels and accelerates mitotic entry upon DNA damage. |
Q37398637 | Marks to stop the clock: histone modifications and checkpoint regulation in the DNA damage response |
Q36900909 | Meiotic roles of Mec1, a budding yeast homolog of mammalian ATR/ATM. |
Q34328693 | Minichromosome maintenance 2 bound with retroviral Gp70 is localized to cytoplasm and enhances DNA-damage-induced apoptosis |
Q37623815 | Modifying chromatin architecture during the response to DNA breakage |
Q36892504 | Modulation of protein phosphatase 2A activity alters androgen-independent growth of prostate cancer cells: therapeutic implications |
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Q33638864 | Monitoring drug-induced gammaH2AX as a pharmacodynamic biomarker in individual circulating tumor cells |
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Q34176919 | Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance |
Q36585497 | Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia |
Q39738661 | Negative regulation of CHK2 activity by protein phosphatase 2A is modulated by DNA damage |
Q38952935 | Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1. |
Q34493945 | Novel functions of the phosphatase SHP2 in the DNA replication and damage checkpoints |
Q37122315 | Nucleosome dynamics as modular systems that integrate DNA damage and repair |
Q38795194 | Oocyte exposure to ZnO nanoparticles inhibits early embryonic development through the γ-H2AX and NF-κB signaling pathways |
Q38777487 | Opposing roles of RNF8/RNF168 and deubiquitinating enzymes in ubiquitination-dependent DNA double-strand break response signaling and DNA-repair pathway choice |
Q34662254 | Orchestration of chromatin-based processes: mind the TRRAP. |
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Q38022938 | Overview for the histone codes for DNA repair |
Q39672062 | Oxidative DNA damage contributes to the toxic activity of propylparaben in mammalian cells |
Q37392383 | PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin |
Q38746849 | PP2A as a master regulator of the cell cycle |
Q28117742 | PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint |
Q33617085 | Papillomaviruses: a systematic review. |
Q35167161 | Paraspeckle protein 1 (PSPC1) is involved in the cisplatin induced DNA damage response--role in G1/S checkpoint |
Q34326211 | Persistent DNA damage after high dose in vivo gamma exposure of minipig skin |
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Q42182193 | Phosphoproteomic analysis reveals that PP4 dephosphorylates KAP-1 impacting the DNA damage response |
Q35131775 | Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit |
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Q35836388 | Protein Phosphatase 2A Inhibition with LB100 Enhances Radiation-Induced Mitotic Catastrophe and Tumor Growth Delay in Glioblastoma. |
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Q47420946 | Protein phosphatase 2A and tau: an orchestrated 'Pas de Deux'. |
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Q36908131 | Protein phosphatase 2A has an essential role in the activation of gamma-irradiation-induced G2/M checkpoint response |
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Q33705076 | Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX. |
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