review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Michael J. Hendzel | Q42407069 |
Ismail H. Ismail | Q55459223 | ||
P2093 | author name string | Michael J Hendzel | |
Ismail Hassan Ismail | |||
P2860 | cites work | Crystal structure of the nucleosome core particle at 2.8 A resolution | Q22122355 |
MDC1 is a mediator of the mammalian DNA damage checkpoint | Q24296229 | ||
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks | Q24299852 | ||
Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling | Q24535638 | ||
A novel chromatin protein, distantly related to histone H2A, is largely excluded from the inactive X chromosome | Q24652092 | ||
Megabase chromatin domains involved in DNA double-strand breaks in vivo | Q24680284 | ||
The language of covalent histone modifications | Q27860931 | ||
A role for Saccharomyces cerevisiae histone H2A in DNA repair. | Q27930827 | ||
Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites | Q27931488 | ||
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery | Q27933727 | ||
INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. | Q27933934 | ||
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 | Q28131715 | ||
Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX | Q28139663 | ||
Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139 | Q28139691 | ||
ATM phosphorylates histone H2AX in response to DNA double-strand breaks | Q28188651 | ||
Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress | Q28201846 | ||
Chromosomal stability and the DNA double-stranded break connection | Q28205315 | ||
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation | Q28206029 | ||
Histone H2A variants H2AX and H2AZ | Q28207014 | ||
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1 | Q28215916 | ||
Chromatin Structure: A Repeating Unit of Histones and DNA | Q28246057 | ||
H2AX: the histone guardian of the genome | Q28274279 | ||
Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals | Q28274301 | ||
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks | Q28291639 | ||
AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching | Q28366125 | ||
Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability | Q28509626 | ||
Genomic instability in mice lacking histone H2AX | Q28589826 | ||
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks | Q29617463 | ||
Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation | Q29617905 | ||
Recombinational DNA double-strand breaks in mice precede synapsis | Q29618790 | ||
Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair | Q29620305 | ||
Core histone N-termini play an essential role in mitotic chromosome condensation | Q30449910 | ||
Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase | Q31070565 | ||
SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization | Q33195747 | ||
Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin | Q33200727 | ||
Kinetics of core histones in living human cells: little exchange of H3 and H4 and some rapid exchange of H2B. | Q33953079 | ||
Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff | Q33963811 | ||
The structure of DNA in the nucleosome core | Q33965908 | ||
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX | Q34031720 | ||
ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells. | Q34049864 | ||
Histone variant H2ABbd confers lower stability to the nucleosome | Q34166137 | ||
Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage | Q34250284 | ||
DNA double-strand break-induced phosphorylation of Drosophila histone variant H2Av helps prevent radiation-induced apoptosis | Q34376575 | ||
The many tales of a tail: carboxyl-terminal tail heterogeneity specializes histone H2A variants for defined chromatin function | Q34626888 | ||
V(D)J recombination: RAG proteins, repair factors, and regulation | Q34667417 | ||
Evolutionary conservation of histone macroH2A subtypes and domains | Q34668581 | ||
H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks | Q34772965 | ||
Maintenance of chromatin states: an open-and-shut case | Q35145809 | ||
Phylogenomics of the nucleosome | Q35570334 | ||
Histones and histone modifications | Q35842800 | ||
The cellular response to general and programmed DNA double strand breaks | Q35848409 | ||
The mechanism of vertebrate nonhomologous DNA end joining and its role in V(D)J recombination | Q35848418 | ||
Histone H2A phosphorylation in DNA double-strand break repair | Q36174600 | ||
Participation of core histone "tails" in the stabilization of the chromatin solenoid | Q36208922 | ||
Translating the histone code into leukemia | Q36259209 | ||
Mechanisms of eukaryotic DNA double strand break repair | Q36348265 | ||
H2AX haploinsufficiency modifies genomic stability and tumor susceptibility | Q36533572 | ||
Differential accessibility of the amino and carboxy termini of histone H2A in the nucleosome and its histone subunits | Q38480579 | ||
Elimination of radiation-induced gamma-H2AX foci in mammalian nucleus can occur by histone exchange | Q40133642 | ||
gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair | Q40347113 | ||
BRCA1 associates with the inactive X chromosome in late S-phase, coupled with transient H2AX phosphorylation | Q40359514 | ||
Phosphorylation of histone H2AX at M phase in human cells without DNA damage response | Q40375352 | ||
Actinomycin D induces histone gamma-H2AX foci and complex formation of gamma-H2AX with Ku70 and nuclear DNA helicase II. | Q40478067 | ||
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions | Q40495236 | ||
Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors | Q40511617 | ||
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation | Q40570996 | ||
UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress | Q40595912 | ||
DNA repair mechanisms involved in gemcitabine cytotoxicity and in the interaction between gemcitabine and cisplatin | Q40680519 | ||
Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts | Q42811761 | ||
Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae | Q43230977 | ||
Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody | Q44140576 | ||
Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes. | Q44378806 | ||
The measurement of DNA strand breaks in rat colonic mucosa by fluorometric analysis of DNA unwinding | Q46080267 | ||
H2AX prevents DNA breaks from progressing to chromosome breaks and translocations | Q46904251 | ||
A likely histone H2A.F/Z variant in Saccharomyces cerevisiae | Q48057064 | ||
Photobleaching of GFP-labeled H2AX in chromatin: H2AX has low diffusional mobility in the nucleus. | Q51842552 | ||
γ-H2AX illuminates meiosis | Q58486287 | ||
The cellular response to DNA double-strand breaks: defining the sensors and mediators | Q63383934 | ||
Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors | Q64387467 | ||
Activation of ataxia telangiectasia mutated by DNA strand break-inducing agents correlates closely with the number of DNA double strand breaks | Q64388842 | ||
53BP1, an activator of ATM in response to DNA damage | Q64388924 | ||
Spatio-temporal dynamics of chromatin containing DNA breaks | Q80159893 | ||
P433 | issue | 1 | |
P304 | page(s) | 73-82 | |
P577 | publication date | 2008-01-01 | |
P1433 | published in | Environmental and Molecular Mutagenesis | Q15724469 |
P1476 | title | The gamma-H2A.X: is it just a surrogate marker of double-strand breaks or much more? | |
P478 | volume | 49 |
Q34165063 | 4D chromatin dynamics in cycling cells: Theodor Boveri's hypotheses revisited |
Q40293697 | A proposal for a novel rationale for critical effect size in dose-response analysis based on a multi-endpoint in vivo study with methyl methanesulfonate |
Q55265956 | Altered DNA repair; an early pathogenic pathway in Alzheimer's disease and obesity. |
Q35198350 | Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery |
Q24632998 | BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair |
Q34188958 | CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage |
Q34565167 | Cell type-dependent induction of DNA damage by 1800 MHz radiofrequency electromagnetic fields does not result in significant cellular dysfunctions |
Q37259025 | Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation |
Q39836469 | Chromosome shattering: a mitotic catastrophe due to chromosome condensation failure |
Q35098038 | DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes |
Q60955618 | Distinctive Nuclear Features of Dinoflagellates with A Particular Focus on Histone and Histone-Replacement Proteins |
Q36574568 | Diversity and Divergence of Dinoflagellate Histone Proteins |
Q37261069 | Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin |
Q35558059 | Geminin overexpression prevents the completion of topoisomerase IIα chromosome decatenation, leading to aneuploidy in human mammary epithelial cells |
Q24299399 | Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells |
Q39031041 | Histone variants on the move: substrates for chromatin dynamics |
Q28274796 | Histone variants--ancient wrap artists of the epigenome |
Q34121601 | Induction and repair of DNA double-strand breaks assessed by gamma-H2AX foci after irradiation with pulsed or continuous proton beams. |
Q28280704 | MRE11 and COM1/SAE2 are required for double-strand break repair and efficient chromosome pairing during meiosis of the protist Tetrahymena |
Q37279340 | Meiotic wave adds extra asymmetry to the development of female chicken gonads. |
Q36825256 | Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterization |
Q37398589 | New developments in post-translational modifications and functions of histone H2A variants |
Q34465287 | Nucleosome adaptability conferred by sequence and structural variations in histone H2A-H2B dimers |
Q37401106 | OGT restrains the expansion of DNA damage signaling |
Q36775097 | On the development of extragonadal and gonadal human germ cells. |
Q48120660 | Periconception onset diabetes is associated with embryopathy and fetal growth retardation, reproductive tract hyperglycosylation and impaired immune adaptation to pregnancy |
Q37335451 | Persistence of histone H2AX phosphorylation after meiotic chromosome synapsis and abnormal centromere cohesion in poly (ADP-ribose) polymerase (Parp-1) null oocytes |
Q90512382 | Persistent accumulation of unrepaired DNA damage in rat cortical neurons: nuclear organization and ChIP-seq analysis of damaged DNA |
Q50670222 | Phosphorylated H2AX in parthenogenetically activated, in vitro fertilized and cloned bovine embryos. |
Q33885281 | Phosphorylation of histone H2A.X by DNA-dependent protein kinase is not affected by core histone acetylation, but it alters nucleosome stability and histone H1 binding |
Q30539255 | Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β |
Q35838986 | Poly(ADP-ribosyl)ation-dependent Transient Chromatin Decondensation and Histone Displacement following Laser Microirradiation |
Q39343299 | Possible novel roles of poly(rC)-binding protein 1 in SH-SY5Y neurocytes: an analysis using a dynamic Bayesian network |
Q92879597 | Preventing the Solid Cancer Progression via Release of Anticancer-Cytokines in Co-Culture with Cold Plasma-Stimulated Macrophages |
Q37800060 | Protein acetylation within the cellular response to radiation. |
Q42013794 | Tetrahymena meiotic nuclear reorganization is induced by a checkpoint kinase-dependent response to DNA damage |
Q34056605 | The catalytic activity of the mitogen-activated protein kinase extracellular signal-regulated kinase 3 is required to sustain CD4+ CD8+ thymocyte survival |
Q64899742 | The histone variant H2A.Z in gene regulation. |
Q38095797 | The variant histone H2A.V of Drosophila--three roles, two guises. |
Q38774044 | The γH2AX DNA damage assay from a drop of blood |
Q42705953 | The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response |
Q37325705 | Toxoplasma H2A variants reveal novel insights into nucleosome composition and functions for this histone family |
Q39543143 | Use of the hollow fiber assay for the evaluation of DNA damaging agents. |
Q39657050 | Use of the γH2AX assay for assessing the genotoxicity of polycyclic aromatic hydrocarbons in human cell lines |
Q41772916 | p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress. |
Q36010145 | uPAR and cathepsin B inhibition enhanced radiation-induced apoptosis in gliomainitiating cells. |
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