Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling

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Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2005PNAS..10218385L
P356DOI10.1073/PNAS.0507975102
P3181OpenCitations bibliographic resource ID3392025
P932PMC publication ID1317944
P698PubMed publication ID16344463
P5875ResearchGate publication ID7426525

P50authorDaeyoup LeeQ38548957
José L GutiérrezQ38591206
Jerry L WorkmanQ89229681
P2093author name stringJie Chen
Bing Li
Samantha G Pattenden
Chris Seidel
Jennifer Gerton
P2860cites workCrystal structure of the nucleosome core particle at 2.8 A resolutionQ22122355
Pericentric heterochromatin becomes enriched with H2A.Z during early mammalian developmentQ24683806
Global nucleosome occupancy in yeastQ24801575
A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatinQ24801790
Crystal structure of a nucleosome core particle containing the variant histone H2A.ZQ27628748
ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complexQ27929959
A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR.Q27933523
A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.Q27933672
Histone H2A.Z regulats transcription and is partially redundant with nucleosome remodeling complexesQ27933818
The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeresQ27939734
Dissecting the regulatory circuitry of a eukaryotic genomeQ28131632
Histone variant H2A.Z is required for early mammalian developmentQ28214088
Histone variants: deviants?Q29391535
Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBFQ29547783
Alteration of nucleosome structure as a mechanism of transcriptional regulationQ29620047
Analysis of nucleosome disruption by ATP-driven chromatin remodeling complexesQ33914680
The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II.Q34168365
Tails of intrigue: phosphorylation of RNA polymerase II mediates histone methylationQ35131664
Essential and nonessential histone H2A variants in Tetrahymena thermophilaQ36561455
A histone variant, H2AvD, is essential in Drosophila melanogasterQ37372881
A method for the rapid sequence-independent amplification of microdissected chromosomal materialQ38513770
Differential repression of transcription factor binding by histone H1 is regulated by the core histone amino termini.Q40794274
The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryoteQ40903819
Global position and recruitment of HATs and HDACs in the yeast genome.Q41233273
A new fluorescence resonance energy transfer approach demonstrates that the histone variant H2AZ stabilizes the histone octamer within the nucleosomeQ44799689
Histone H2A.Z is widely but nonrandomly distributed in chromosomes of Drosophila melanogasterQ47071028
RNA interference demonstrates a novel role for H2A.Z in chromosome segregationQ47349040
Ssn6-Tup1 regulates RNR3 by positioning nucleosomes and affecting the chromatin structure at the upstream repression sequence.Q52543433
Regions of variant histone His2AvD required for Drosophila development.Q52571223
Evidence for nucleosome depletion at active regulatory regions genome-wideQ54998820
Conserved Histone Variant H2A.Z Protects Euchromatin from the Ectopic Spread of Silent HeterochromatinQ58212661
Histone 2A, a heteromorphous family of eight protein speciesQ71289687
The essential histone variant H2A.Z regulates the equilibrium between different chromatin conformational statesQ77649147
H2A.Z alters the nucleosome surface to promote HP1alpha-mediated chromatin fiber foldingQ81013899
P433issue51
P407language of work or nameEnglishQ1860
P304page(s)18385-18390
P577publication date2005-12-12
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titlePreferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling
P478volume102

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cites work (P2860)
Q43155322A canonical promoter organization of the transcription machinery and its regulators in the Saccharomyces genome
Q41936960A conserved acidic patch in the Myb domain is required for activation of an endogenous target gene and for chromatin binding
Q37829707A modified epigenetics toolbox to study histone modifications on the nucleosome core.
Q24294901A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription
Q27692030ATP dependent chromatin remodeling enzymes in embryonic stem cells
Q35865561ATP-dependent chromatin remodeling factors and DNA damage repair
Q35651278Access to DNA establishes a secondary target site bias for the yeast retrotransposon Ty5.
Q39414538Acetylation of H3 K56 is required for RNA polymerase II transcript elongation through heterochromatin in yeast.
Q27937452Acetylation of the SUN protein Mps3 by Eco1 regulates its function in nuclear organization.
Q33564388Actin-related protein Arp6 influences H2A.Z-dependent and -independent gene expression and links ribosomal protein genes to nuclear pores
Q34299231Activity of a C-terminal Plant Homeodomain (PHD) of Msc1 Is Essential for Function
Q40541541An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair
Q24671488Analysis of human histone H2AZ deposition in vivo argues against its direct role in epigenetic templating mechanisms
Q27682061Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z
Q27658459Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation
Q43179790Asymmetric nucleosomes flank promoters in the budding yeast genome
Q33568422Chapter 5. Nuclear actin-related proteins in epigenetic control
Q30437379Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates
Q36177486Chd1 and yFACT act in opposition in regulating transcription.
Q37704663Chd1 remodelers maintain open chromatin and regulate the epigenetics of differentiation.
Q26799305Chromatin Dynamics in Vivo: A Game of Musical Chairs
Q35748234Chromatin and transcription in yeast
Q39539723Chromatin remodeling by imitation switch (ISWI) class ATP-dependent remodelers is stimulated by histone variant H2A.Z.
Q41864430Chromatin structure and expression of a gene transcribed by RNA polymerase III are independent of H2A.Z deposition.
Q37398600Connection between histone H2A variants and chromatin remodeling complexes
Q34402955Control of embryonic stem cell identity by nucleosome remodeling enzymes
Q27939957Cse4 is part of an octameric nucleosome in budding yeast
Q50561900DNA Replication Is Required for Circadian Clock Function by Regulating Rhythmic Nucleosome Composition.
Q34022215Decoding the Epigenetic Language of Plant Development
Q28484353Deposition of histone variant H2A.Z within gene bodies regulates responsive genes
Q36748104Different genetic functions for the Rpd3(L) and Rpd3(S) complexes suggest competition between NuA4 and Rpd3(S)
Q38808036Different phosphoisoforms of RNA polymerase II engage the Rtt103 termination factor in a structurally analogous manner.
Q33414877Discriminating nucleosomes containing histone H2A.Z or H2A based on genetic and epigenetic information
Q47332390Downstream promoter interactions of TFIID TAFs facilitate transcription reinitiation
Q34794271Drosophila histone H2A variant (H2Av) controls poly(ADP-ribose) polymerase 1 (PARP1) activation in chromatin
Q37128008Dynamic histone variant exchange accompanies gene induction in T cells
Q26851348Dynamics of histone variant H3.3 and its coregulation with H2A.Z at enhancers and promoters
Q41579365Eaf1 Links the NuA4 Histone Acetyltransferase Complex to Htz1 Incorporation and Regulation of Purine Biosynthesis
Q36981211Epigenetic regulation of centromeric chromatin: old dogs, new tricks?
Q37053543Epigenetic regulation of the ribosomal cistron seasonally modulates enrichment of H2A.Z and H2A.Zub in response to different environmental inputs in carp (Cyprinus carpio)
Q38891308Expression of Non-acetylatable H2A.Z in Myoblast Cells Blocks Myoblast Differentiation through Disruption of MyoD Expression
Q36579359Five repair pathways in one context: chromatin modification during DNA repair
Q35004993Full and partial genome-wide assembly and disassembly of the yeast transcription machinery in response to heat shock
Q30427610Genetic analysis implicates the Set3/Hos2 histone deacetylase in the deposition and remodeling of nucleosomes containing H2A.Z.
Q42278134Genome-wide analysis of chromatin status using tiling microarrays
Q37077306Genome-wide approaches to studying chromatin modifications
Q36567360Genome-wide patterns of histone modifications in yeast.
Q92088931Genome-wide reconstitution of chromatin transactions reveals that RSC preferentially disrupts H2AZ-containing nucleosomes
Q33611702Genome-wide views of chromatin structure
Q36082186Genome-wide, as opposed to local, antisilencing is mediated redundantly by the euchromatic factors Set1 and H2A.Z.
Q36471383Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae.
Q33954563Genomic organization of H2Av containing nucleosomes in Drosophila heterochromatin
Q33864143Global analysis for functional residues of histone variant Htz1 using the comprehensive point mutant library
Q47155918Global inhibition of transcription causes an increase in histone H2A.Z incorporation within gene bodies
Q36798739Global investigation of protein-protein interactions in yeast Saccharomyces cerevisiae using re-occurring short polypeptide sequences.
Q34419379Global turnover of histone post-translational modifications and variants in human cells
Q34477589H2A.Z (Htz1) controls the cell-cycle-dependent establishment of transcriptional silencing at Saccharomyces cerevisiae telomeres
Q48032398H2A.Z and H2B.Z double-variant nucleosomes define intergenic regions and dynamically occupy var gene promoters in the malaria parasite Plasmodium falciparum
Q41179603H2A.Z controls the stability and mobility of nucleosomes to regulate expression of the LH genes
Q35576229H2A.Z marks antisense promoters and has positive effects on antisense transcript levels in budding yeast
Q33279444H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state
Q39989822H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment
Q37362553H3.3 actively marks enhancers and primes gene transcription via opening higher-ordered chromatin.
Q24317641H3.3/H2A.Z double variant-containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions
Q33653254HAT2 mediates histone H4K4 acetylation and affects micrococcal nuclease sensitivity of chromatin in Leishmania donovani
Q40335328Histone Chaperone Nap1 Is a Major Regulator of Histone H2A-H2B Dynamics at the Inducible GAL Locus
Q33371693Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks
Q37352034Histone H2A.Z cooperates with RNAi and heterochromatin factors to suppress antisense RNAs
Q37247116Histone H2A.Z is essential for estrogen receptor signaling
Q84865644Histone H2A.Z regulates the expression of several classes of phosphate starvation response genes but not as a transcriptional activator
Q43159915Histone H3 lysine 36 dimethylation (H3K36me2) is sufficient to recruit the Rpd3s histone deacetylase complex and to repress spurious transcription
Q35025031Histone H3 variants and their potential role in indexing mammalian genomes: the "H3 barcode hypothesis"
Q92074963Histone Tail Dynamics in Partially Disassembled Nucleosomes During Chromatin Remodeling
Q27939494Histone variant H2A.Z and RNA polymerase II transcription elongation
Q89475630Histone variant H2A.Z deposition and acetylation directs the canonical Notch signaling response
Q33581966Histone variant H2A.Z regulates centromere silencing and chromosome segregation in fission yeast
Q27934483Histone variant Htz1 promotes histone H3 acetylation to enhance nucleotide excision repair in Htz1 nucleosomes
Q26827964Histone variants as emerging regulators of embryonic stem cell identity
Q33588109Histone variants: dynamic punctuation in transcription
Q33630867Histone variants: emerging players in cancer biology
Q38355887Histone variants: the artists of eukaryotic chromatin
Q37514183How eukaryotic genes are transcribed
Q33569829Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones
Q34020211Identification and characterization of the two isoforms of the vertebrate H2A.Z histone variant
Q33426080Identification of novel transcriptional regulators involved in macrophage differentiation and activation in U937 cells
Q41889467Infrequently transcribed long genes depend on the Set2/Rpd3S pathway for accurate transcription
Q33565190Insights into chromatin structure and dynamics in plants
Q27938380Interaction of a DNA Zip Code with the Nuclear Pore Complex Promotes H2A.Z Incorporation and INO1 Transcriptional Memory
Q36579347Is histone loss a common feature of DNA metabolism regulation?
Q38409542Isw1 functions in parallel with the NuA4 and Swr1 complexes in stress-induced gene repression
Q38285917Key functional regions in the histone variant H2A.Z C-terminal docking domain
Q47550184Learning and Age-Related Changes in Genome-wide H2A.Z Binding in the Mouse Hippocampus.
Q37176820MYSTs mark chromatin for chromosomal functions
Q39318001Maintenance of heterochromatin boundary and nucleosome composition at promoters by the Asf1 histone chaperone and SWR1-C chromatin remodeler in Saccharomyces cerevisiae.
Q36738573Mechanisms of ATP dependent chromatin remodeling
Q37180651Mechanisms that specify promoter nucleosome location and identity
Q36177449Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin
Q36287862Msc1 acts through histone H2A.Z to promote chromosome stability in Schizosaccharomyces pombe
Q36208613Multivalent di-nucleosome recognition enables the Rpd3S histone deacetylase complex to tolerate decreased H3K36 methylation levels
Q31139142Multivalent engagement of TFIID to nucleosomes
Q40069093Myb proteins regulate expression of histone variant H2A.Z during thymocyte development
Q30433388Nap1 and Chz1 have separate Htz1 nuclear import and assembly functions
Q92883511Nascent chromatin occupancy profiling reveals locus- and factor-specific chromatin maturation dynamics behind the DNA replication fork
Q37629627NuA4 and SWR1-C: two chromatin-modifying complexes with overlapping functions and components
Q27936275NuA4-dependent acetylation of nucleosomal histones H4 and H2A directly stimulates incorporation of H2A.Z by the SWR1 complex.
Q27930805NuA4-directed chromatin transactions throughout the Saccharomyces cerevisiae genome
Q37548517Nucleosome fragility is associated with future transcriptional response to developmental cues and stress in C. elegans
Q38885861Nucleosome mobility and the regulation of gene expression: Insights from single-molecule studies.
Q37326387Nucleosome organization in the Drosophila genome.
Q37885611Nucleosome positioning in Saccharomyces cerevisiae.
Q35840889Nucleosome stability mediated by histone variants H3.3 and H2A.Z.
Q24672606Opposing roles for Set2 and yFACT in regulating TBP binding at promoters
Q38072728Organizing the genome with H2A histone variants
Q34199248PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution
Q42510780Physical and functional interactions between Drosophila homologue of Swc6/p18Hamlet subunit of the SWR1/SRCAP chromatin-remodeling complex with the DNA repair/transcription factor TFIIH.
Q26852536Post-translational modifications of histones that influence nucleosome dynamics
Q38169520Post-translational modifications of the histone variant H2AZ.
Q36865040Pyrosequencing positions nucleosomes precisely
Q27938414RSC exploits histone acetylation to abrogate the nucleosomal block to RNA polymerase II elongation
Q28472344RSF governs silent chromatin formation via histone H2Av replacement
Q35959575Regulation of Budding Yeast CENP-A levels Prevents Misincorporation at Promoter Nucleosomes and Transcriptional Defects.
Q54188370Regulation of chromatin states and gene expression during HSN neuronal maturation is mediated by EOR-1/PLZF, MAU-2/cohesin loader, and SWI/SNF complex.
Q37398628Regulation of gene expression and cellular proliferation by histone H2A.Z.
Q58924948Repression of flowering in Arabidopsis requires activation of FLOWERING LOCUS C expression by the histone variant H2A.Z
Q27348721Restricting dosage compensation complex binding to the X chromosomes by H2A.Z/HTZ-1
Q36579373Reuniting the contrasting functions of H2A.Z.
Q51563325Revealing epigenetic patterns in gene regulation through integrative analysis of epigenetic interaction network.
Q33416352Role of the histone variant H2A.Z/Htz1p in TBP recruitment, chromatin dynamics, and regulated expression of oleate-responsive genes
Q33617819Roles for H2A.Z and its acetylation in GAL1 transcription and gene induction, but not GAL1-transcriptional memory
Q90163871Roles of the INO80 and SWR1 Chromatin Remodeling Complexes in Plants
Q43259704SAS-mediated acetylation of histone H4 Lys 16 is required for H2A.Z incorporation at subtelomeric regions in Saccharomyces cerevisiae
Q38698612SETD2 and histone H3 lysine 36 methylation deficiency in advanced systemic mastocytosis
Q27934592SWI/SNF-like chromatin remodeling factor Fun30 supports point centromere function in S. cerevisiae.
Q42064469SWR-C and INO80 chromatin remodelers recognize nucleosome-free regions near +1 nucleosomes.
Q33826542SWR1 complex poises heterochromatin boundaries for antisilencing activity propagation.
Q34752031Scm3 is a centromeric nucleosome assembly factor
Q27932939Stepwise Histone Replacement by SWR1 Requires Dual Activation with Histone H2A.Z and Canonical Nucleosome
Q24339519TIP48/Reptin and H2A.Z requirement for initiating chromatin remodeling in estrogen-activated transcription
Q34918097Targeting of the SUN protein Mps3 to the inner nuclear membrane by the histone variant H2A.Z.
Q47288294Temporal regulation of chromatin during myoblast differentiation.
Q33258828Temporal regulation of foregut development by HTZ-1/H2A.Z and PHA-4/FoxA
Q35823742The 19S proteasome subcomplex promotes the targeting of NuA4 HAT to the promoters of ribosomal protein genes to facilitate the recruitment of TFIID for transcriptional initiation in vivo
Q36631422The Genomes of Three Uneven Siblings: Footprints of the Lifestyles of Three Trichoderma Species
Q27930026The Isw2 chromatin-remodeling ATPase cooperates with the Fkh2 transcription factor to repress transcription of the B-type cyclin gene CLB2
Q37085208The MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila melanogaster X chromosome
Q33658624The SWR1 histone replacement complex causes genetic instability and genome-wide transcription misregulation in the absence of H2A.Z.
Q30884260The Schizosaccharomyces pombe JmjC-protein, Msc1, prevents H2A.Z localization in centromeric and subtelomeric chromatin domains
Q58751869The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects
Q27936207The Tup1 corepressor directs Htz1 deposition at a specific promoter nucleosome marking the GAL1 gene for rapid activation
Q35070913The X and Y chromosomes assemble into H2A.Z-containing [corrected] facultative heterochromatin [corrected] following meiosis.
Q34092981The current state of chromatin immunoprecipitation
Q24336460The euchromatic and heterochromatic landscapes are shaped by antagonizing effects of transcription on H2A.Z deposition
Q84414718The evolution of epitype
Q37038673The gamma-H2A.X: is it just a surrogate marker of double-strand breaks or much more?
Q33369072The genomic distribution and function of histone variant HTZ-1 during C. elegans embryogenesis
Q36352391The histone variant H2A.W defines heterochromatin and promotes chromatin condensation in Arabidopsis
Q64899742The histone variant H2A.Z in gene regulation.
Q37288973The histone variant His2Av is required for adult stem cell maintenance in the Drosophila testis
Q36226790The influence of DNA sequence on epigenome-induced pathologies
Q21092478The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome
Q93088380The repressive role of Arabidopsis H2A.Z in transcriptional regulation depends on AtBMI1 activity
Q36270857The right place at the right time: chaperoning core histone variants
Q36579354The role of chromatin structure in regulating stress-induced transcription in Saccharomyces cerevisiae
Q37687220The role of histone modifications and variants in regulating gene expression in breast cancer.
Q34082953Threonine-4 of the budding yeast RNAP II CTD couples transcription with Htz1-mediated chromatin remodeling.
Q37325705Toxoplasma H2A variants reveal novel insights into nucleosome composition and functions for this histone family
Q42911076Transcription alters chromosomal locations of cohesin in Saccharomyces cerevisiae
Q42244178Transcription factor CTF1 acts as a chromatin domain boundary that shields human telomeric genes from silencing
Q38043829Transcription-associated histone modifications and cryptic transcription
Q37398592Transcriptional and epigenetic functions of histone variant H2A.Z.
Q52663127Transcriptional regulation mediated by H2A.Z via ANP32e-dependent inhibition of protein phosphatase 2A.
Q34613479Translational and rotational settings of H2A.Z nucleosomes across the Saccharomyces cerevisiae genome.
Q34947175USP10 deubiquitylates the histone variant H2A.Z and both are required for androgen receptor-mediated gene activation
Q35720902Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation
Q41767877Yeast H2A.Z, FACT complex and RSC regulate transcription of tRNA gene through differential dynamics of flanking nucleosomes.
Q35917048p21 transcription is regulated by differential localization of histone H2A.Z.