Tetrahymena meiotic nuclear reorganization is induced by a checkpoint kinase-dependent response to DNA damage

scientific article published on 18 March 2009

Tetrahymena meiotic nuclear reorganization is induced by a checkpoint kinase-dependent response to DNA damage is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1091/MBC.E08-10-1058
P932PMC publication ID2675622
P698PubMed publication ID19297526
P5875ResearchGate publication ID24211459

P50authorKazufumi MochizukiQ38329350
P2093author name stringJosef Loidl
P2860cites workMacronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryoteQ21146044
Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaksQ24531151
A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signalingQ24599676
Meiotic double-strand breaks at the interface of chromosome movement, chromosome remodeling, and reductional divisionQ24646919
Multiple branches of the meiotic recombination pathway contribute independently to homolog pairing and stable juxtaposition during meiosis in budding yeastQ27933164
Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsisQ28279936
Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stagesQ28506028
Centromere and telomere movements during early meiotic prophase of mouse and man are associated with the onset of chromosome pairingQ28609152
Recombinational DNA double-strand breaks in mice precede synapsisQ29618790
Tetrahymena as a laboratory organism: useful strains, cell culture, and cell line maintenanceQ33741629
TIF1 Represses rDNA replication initiation, but promotes normal S phase progression and chromosome transmission in TetrahymenaQ33841352
Atm inactivation results in aberrant telomere clustering during meiotic prophaseQ33958817
Germline and somatic transformation of mating Tetrahymena thermophila by particle bombardmentQ33969895
A bouquet makes ends meetQ34085740
How do meiotic chromosomes meet their homologous partners?: lessons from fission yeastQ34269339
The CNA1 histone of the ciliate Tetrahymena thermophila is essential for chromosome segregation in the germline micronucleusQ34298429
DNA damage-induced activation of ATM and ATM-dependent signaling pathwaysQ34336538
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmanninQ34663629
H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaksQ34772965
TIF1 activates the intra-S-phase checkpoint response in the diploid micronucleus and amitotic polyploid macronucleus of Tetrahymena.Q35190990
Spo11 and the Formation of DNA Double-Strand Breaks in MeiosisQ35212439
The cellular response to general and programmed DNA double strand breaksQ35848409
The role of the DNA double-strand break response network in meiosisQ35848542
A bouquet of chromosomesQ35865439
ASY1 mediates AtDMC1-dependent interhomolog recombination during meiosis in Arabidopsis.Q35946391
A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombinationQ36274716
From early homologue recognition to synaptonemal complex formationQ36434484
Cisplatin increases meiotic crossing-over in miceQ36554672
Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosisQ36982156
Meiotic chromosomes move by linkage to dynamic actin cables with transduction of force through the nuclear envelopeQ37013008
The gamma-H2A.X: is it just a surrogate marker of double-strand breaks or much more?Q37038673
A beta-tubulin mutation selectively uncouples nuclear division and cytokinesis in Tetrahymena thermophilaQ37579825
The initiation of meiotic chromosome pairing: the cytological viewQ37791630
Organization and pairing of meiotic chromosomes in the ciliate Tetrahymena thermophilaQ38476678
Bouquet formation in budding yeast: initiation of recombination is not required for meiotic telomere clusteringQ38500975
DNA double-strand breaks, but not crossovers, are required for the reorganization of meiotic nuclei in TetrahymenaQ38604234
Architecture of the nuclear periphery of rat pachytene spermatocytes: distribution of nuclear envelope proteins in relation to synaptonemal complex attachment sitesQ38610615
Centromeric histone H3 is essential for vegetative cell division and for DNA elimination during conjugation in Tetrahymena thermophilaQ41492080
Evidence for the coincident initiation of homolog pairing and synapsis during the telomere-clustering (bouquet) stage of meiotic prophaseQ41720624
Phosphorylation of the SQ H2A.X motif is required for proper meiosis and mitosis in Tetrahymena thermophilaQ42738107
Assessment of DNA double-strand breaks and gammaH2AX induced by the topoisomerase II poisons etoposide and mitoxantroneQ43244109
Cytologic and autoradiographic studies of the micronucleus at meiotic prophase in Tetrahymena pyriformisQ43904465
Caffeine inhibits checkpoint responses without inhibiting the ataxia-telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) protein kinasesQ44504054
The effect of phosphoinositide 3-kinase inhibitors on programmed nuclear degradation in Tetrahymena and fate of surviving nuclei.Q44981509
Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase.Q45233939
Hop1 and the meiotic DNA-damage response.Q45990053
DNA repair by the MRN complex: break it to make it.Q52589691
Factors directing telomere dynamics in synaptic meiosis.Q52931643
H2AX phosphorylation after UV irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase.Q53331348
The telomere bouquet controls the meiotic spindle.Q53540686
THE LEPTOTENE-ZYGOTENE TRANSITION OF MEIOSISQ56136641
A cytological study of micronuclear elongation during conjugation in TetrahymenaQ67527278
Effect of the antitubulin drug nocodazole on meiosis and postmeiotic development in Tetrahymena thermophila. Induction of achiasmatic meiosisQ70108966
P4510describes a project that usesImageJQ1659584
P433issue9
P304page(s)2428-2437
P577publication date2009-03-18
P1433published inMolecular Biology of the CellQ2338259
P1476titleTetrahymena meiotic nuclear reorganization is induced by a checkpoint kinase-dependent response to DNA damage
P478volume20

Reverse relations

cites work (P2860)
Q37699030A Zip3-like protein plays a role in crossover formation in the SC-less meiosis of the protist Tetrahymena
Q57793791A chromatin-associated protein required for inducing and limiting meiotic DNA double-strand break formation
Q34650050A single cohesin complex performs mitotic and meiotic functions in the protist tetrahymena
Q91800413An MCM family protein promotes interhomolog recombination by preventing precocious intersister repair of meiotic DSBs
Q35719565Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena
Q39623240Colchicine-induced degeneration of the micronucleus during conjugation in Tetrahymena
Q26768639DNA double-strand break formation and repair in Tetrahymena meiosis
Q34872449Developmental regulation of the Tetrahymena thermophila origin recognition complex
Q36205220E2fl1 is a meiosis-specific transcription factor in the protist Tetrahymena thermophila
Q51533437Kinesin-14 is Important for Chromosome Segregation During Mitosis and Meiosis in the Ciliate Tetrahymena thermophila.
Q37574327Local chromosome context is a major determinant of crossover pathway biochemistry during budding yeast meiosis.
Q28280704MRE11 and COM1/SAE2 are required for double-strand break repair and efficient chromosome pairing during meiosis of the protist Tetrahymena
Q34471736Msh4 and Msh5 function in SC-independent chiasma formation during the streamlined meiosis of Tetrahymena
Q24603667Mus81 nuclease and Sgs1 helicase are essential for meiotic recombination in a protist lacking a synaptonemal complex
Q64065581Noncanonical Contributions of MutLγ to VDE-Initiated Crossovers During Meiosis
Q35033565Phosphoproteomic analysis of protein phosphorylation networks in Tetrahymena thermophila, a model single-celled organism.
Q33829179Post-meiotic DNA double-strand breaks occur in Tetrahymena, and require Topoisomerase II and Spo11.
Q42144427Quantitative proteomics reveals that the specific methyltransferases Txr1p and Ezl2p differentially affect the mono-, di- and trimethylation states of histone H3 lysine 27 (H3K27).
Q35093505Tetrahymena thermophila, a unicellular eukaryote with separate germline and somatic genomes
Q35967882The key role of CYC2 during meiosis in Tetrahymena thermophila.
Q34248122The meiotic checkpoint network: step-by-step through meiotic prophase
Q33350963The recombinases Rad51 and Dmc1 play distinct roles in DNA break repair and recombination partner choice in the meiosis of Tetrahymena

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