scholarly article | Q13442814 |
P50 | author | Cheryl Arrowsmith | Q5092682 |
Brian D Strahl | Q41544665 | ||
Peter J. Brown | Q42713845 | ||
Yunxiang Mu | Q55175819 | ||
Scott B Rothbart | Q62070938 | ||
Pavel Mader | Q92749368 | ||
P2093 | author name string | Aiping Dong | |
Gaofeng Cui | |||
Georges Mer | |||
Kevin M McBride | |||
Stephen V Frye | |||
Jacqueline L Norris | |||
William P Janzen | |||
Bradley M Dickson | |||
Lindsey I James | |||
Brandi M Baughman | |||
Michael T Perfetti | |||
P2860 | cites work | Translating the Histone Code | Q22065840 |
MDC1 is a mediator of the mammalian DNA damage checkpoint | Q24296229 | ||
The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks | Q24298486 | ||
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly | Q24300428 | ||
Tudor, MBT and chromo domains gauge the degree of lysine methylation | Q24301294 | ||
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites | Q24306486 | ||
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins | Q24309287 | ||
The DNA-damage response in human biology and disease | Q24606586 | ||
Human CtIP promotes DNA end resection | Q24646062 | ||
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair | Q24669691 | ||
Small-Molecule Ligands of Methyl-Lysine Binding Proteins | Q27667285 | ||
Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination | Q27676128 | ||
The language of covalent histone modifications | Q27860931 | ||
53BP1 regulates DSB repair using Rif1 to control 5' end resection | Q28000120 | ||
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice | Q28000121 | ||
53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage | Q28236024 | ||
A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency | Q28256846 | ||
The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination | Q28592784 | ||
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks | Q29465538 | ||
53BP1 is required for class switch recombination | Q29465541 | ||
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. | Q29465548 | ||
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching | Q29465549 | ||
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark | Q29465773 | ||
The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse | Q29618622 | ||
Epigenetic modifications and human disease | Q29619753 | ||
The emerging field of dynamic lysine methylation of non-histone proteins. | Q30368231 | ||
Identification of non-peptide malignant brain tumor (MBT) repeat antagonists by virtual screening of commercially available compounds | Q30497277 | ||
Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins | Q33518291 | ||
Preparation of recombinant peptides with site- and degree-specific lysine (13)C-methylation | Q33805946 | ||
The art of the chemical probe | Q34098693 | ||
Setting expectations in molecular optimizations: Strengths and limitations of commonly used composite parameters | Q34369771 | ||
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. | Q34503454 | ||
p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice | Q34784963 | ||
Small-molecule ligands of methyl-lysine binding proteins: optimization of selectivity for L3MBTL3. | Q34990803 | ||
Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1. | Q35125130 | ||
CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiation. | Q36062092 | ||
Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1 | Q36320732 | ||
Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain | Q36625174 | ||
Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling | Q37000240 | ||
BRCA1 and BRCA2: different roles in a common pathway of genome protection | Q37149848 | ||
Epigenetic modifications as therapeutic targets | Q37800011 | ||
BRCA mutations in the management of breast cancer: the state of the art | Q37801266 | ||
gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair | Q40347113 | ||
Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation | Q42582794 | ||
Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest | Q42738049 | ||
Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA. | Q44489693 | ||
Using halogen bonds to address the protein backbone: a systematic evaluation | Q47301557 | ||
Ligand binding efficiency: trends, physical basis, and implications | Q80992297 | ||
P433 | issue | 4 | |
P304 | page(s) | 1072-1081 | |
P577 | publication date | 2015-01-28 | |
P1433 | published in | ACS Chemical Biology | Q165583 |
P1476 | title | Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1. | |
P478 | volume | 10 |
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Q36914593 | Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform. |
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Q47419320 | Phosphorylation promotes activation-induced cytidine deaminase activity at the Myc oncogene |
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Q52767723 | Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin. |
Q38434032 | Selective Inhibition of CBX6: A Methyllysine Reader Protein in the Polycomb Family |
Q89511226 | Small Molecules Targeting the Specific Domains of Histone-Mark Readers in Cancer Therapy |
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