Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest

scientific article published on 26 April 2010

Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.01644-09
P932PMC publication ID2897583
P698PubMed publication ID20421415

P50authorKirsten DahmQ44194247
Atsushi ShibataQ57015061
P2093author name stringPenny A Jeggo
Aaron A Goodarzi
Markus Löbrich
Olivia Barton
Dorothee Deckbar
Angela T Noon
P2860cites workLinkage of ATM to cell cycle regulation by the Chk2 protein kinaseQ22008502
MDC1 is a mediator of the mammalian DNA damage checkpointQ24296229
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephalyQ24302120
XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joiningQ24302150
Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.Q24533460
Nonhomologous end joining and V(D)J recombination require an additional factorQ24554076
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2Q24647310
Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrestQ24677047
Chromosome breakage after G2 checkpoint releaseQ24683383
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.Q27919669
A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndromeQ28183834
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1Q28215916
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signalsQ28292900
Pathways of DNA double-strand break repair during the mammalian cell cycleQ28608969
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaksQ29614215
Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest.Q30657462
53BP1, a mediator of the DNA damage checkpointQ34153067
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiationQ34300338
Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent mannerQ34324643
DNA double-strand break repair: all's well that ends wellQ34555274
Mechanism of DNA double-strand break repair by non-homologous end joiningQ34557861
ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stallingQ34653133
The two edges of the ATM sword: co-operation between repair and checkpoint functionsQ36199250
Contribution of DNA repair and cell cycle checkpoint arrest to the maintenance of genomic stabilityQ36517206
Differential usage of non-homologous end-joining and homologous recombination in double strand break repairQ36522562
ATR/Mec1: coordinating fork stability and repair.Q37397197
53BP1 promotes ATM activity through direct interactions with the MRN complexQ39352316
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repairQ39750906
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiationQ40570996
A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivityQ40595505
Chk2 is required for optimal mitotic delay in response to irradiation-induced DNA damage incurred in G2 phase.Q53330219
Radiosensitivity in ataxia-telangiectasia: anomalies in radiation-induced cell cycle delayQ72670297
Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stabilityQ78960906
P433issue13
P407language of work or nameEnglishQ1860
P304page(s)3371-3383
P577publication date2010-04-26
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleRole of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest
P478volume30

Reverse relations

cites work (P2860)
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