| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/ONC.2011.451 |
| P698 | PubMed publication ID | 21963855 |
| P50 | author | Libor Macůrek | Q77898702 |
| René H. Medema | Q30788066 | ||
| P2093 | author name string | L Macůrek | |
| P2860 | cites work | GADD45 induction of a G2/M cell cycle checkpoint | Q22009111 |
| The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis | Q24291114 | ||
| A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55 | Q24294369 | ||
| The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop | Q24297633 | ||
| Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair | Q24297983 | ||
| SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response | Q24298620 | ||
| ATM-mediated phosphorylation activates the tumor-suppressive function of B56γ-PP2A | Q24298893 | ||
| MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks | Q24299852 | ||
| Chk2 activates E2F-1 in response to DNA damage | Q24300634 | ||
| TAO kinases mediate activation of p38 in response to DNA damage | Q24301324 | ||
| Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase | Q24301325 | ||
| DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization | Q24302100 | ||
| A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling | Q24306275 | ||
| ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage | Q24306743 | ||
| Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery | Q24311665 | ||
| NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint | Q24313589 | ||
| The decision to enter mitosis: feedback and redundancy in the mitotic entry network | Q24315132 | ||
| F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage | Q24321698 | ||
| M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP | Q24329203 | ||
| Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery | Q24336194 | ||
| Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner | Q24336721 | ||
| MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation | Q24337242 | ||
| 14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage | Q24338975 | ||
| Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases | Q24519082 | ||
| Plk1 promotes nuclear translocation of human Cdc25C during prophase | Q24522577 | ||
| PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints | Q24527393 | ||
| Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints | Q24538300 | ||
| p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation | Q24596239 | ||
| Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway | Q24607221 | ||
| Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications | Q24608343 | ||
| Human CtIP promotes DNA end resection | Q24646062 | ||
| Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase | Q24647659 | ||
| The combined status of ATM and p53 link tumor development with therapeutic response | Q24652535 | ||
| In vivo activation of the p53 pathway by small-molecule antagonists of MDM2 | Q27642888 | ||
| Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes | Q27860662 | ||
| The DNA Damage Response: Making It Safe to Play with Knives | Q27861055 | ||
| Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry | Q28115829 | ||
| DNA damage-induced activation of p53 by the checkpoint kinase Chk2 | Q28138195 | ||
| Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase | Q28186851 | ||
| Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45 | Q28199142 | ||
| DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation | Q28206029 | ||
| p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage | Q37342444 | ||
| The G(2) DNA damage checkpoint: could this ancient regulator be the Achilles heel of cancer? | Q37539561 | ||
| Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A. | Q37605239 | ||
| WIP1 phosphatase at the crossroads of cancer and aging | Q37625095 | ||
| Recent advances in the therapeutic perspectives of Nutlin-3. | Q37851525 | ||
| MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo | Q38431323 | ||
| 53BP1 promotes ATM activity through direct interactions with the MRN complex | Q39352316 | ||
| PPM1D silencing by lentiviral-mediated RNA interference inhibits proliferation and invasion of human glioma cells. | Q39588924 | ||
| Cdc25B is negatively regulated by p53 through Sp1 and NF-Y transcription factors. | Q39606687 | ||
| ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage | Q39622746 | ||
| p53-dependent repression of polo-like kinase-1 (PLK1). | Q39641693 | ||
| Dynamics of the p53-Mdm2 feedback loop in individual cells | Q39674103 | ||
| A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage. | Q39685318 | ||
| Recovery from a DNA-damage-induced G2 arrest requires Cdk-dependent activation of FoxM1. | Q39716932 | ||
| Repo-man controls a protein phosphatase 1-dependent threshold for DNA damage checkpoint activation | Q39734421 | ||
| Negative regulation of CHK2 activity by protein phosphatase 2A is modulated by DNA damage | Q39738661 | ||
| Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition | Q39747969 | ||
| Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex. | Q39752528 | ||
| Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents | Q39779509 | ||
| Wip1 confers G2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression. | Q39807046 | ||
| PPM1D is a potential therapeutic target in ovarian clear cell carcinomas | Q39871749 | ||
| Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage. | Q39983426 | ||
| Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response. | Q40339254 | ||
| gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair | Q40347113 | ||
| Chemical inhibition of Wip1 phosphatase contributes to suppression of tumorigenesis | Q40356588 | ||
| The cyclin-dependent kinase inhibitor UCN-01 plus cisplatin in advanced solid tumors: a California cancer consortium phase I pharmacokinetic and molecular correlative trial | Q40408817 | ||
| Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage. | Q40478360 | ||
| Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells | Q40518897 | ||
| Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase | Q40703602 | ||
| Chk1 regulates the density of active replication origins during the vertebrate S phase. | Q41847676 | ||
| Phosphorylation and degradation of MdmX is inhibited by Wip1 phosphatase in the DNA damage response | Q41967616 | ||
| Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60. | Q42672338 | ||
| Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters. | Q42724753 | ||
| Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest | Q42738049 | ||
| MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil | Q43182482 | ||
| Cdc25B activity is regulated by 14-3-3. | Q43683797 | ||
| Questioning the role of checkpoint kinase 2 in the p53 DNA damage response | Q44374509 | ||
| The Chk2 tumor suppressor is not required for p53 responses in human cancer cells | Q44374511 | ||
| PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break | Q44384534 | ||
| Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1. | Q45967119 | ||
| The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases | Q46948160 | ||
| Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway | Q48022280 | ||
| OsHAL3 mediates a new pathway in the light-regulated growth of rice. | Q48069473 | ||
| UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53. | Q50537563 | ||
| Chk1 is required for spindle checkpoint function. | Q52576772 | ||
| Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice. | Q53346673 | ||
| Gadd45a and Gadd45b protect hematopoietic cells from UV-induced apoptosis via distinct signaling pathways, including p38 activation and JNK inhibition. | Q53625972 | ||
| Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage | Q57188003 | ||
| Polo-like kinase-1 is a target of the DNA damage checkpoint | Q57985159 | ||
| Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo | Q59098643 | ||
| Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways | Q61849111 | ||
| The polo-like kinase 1 regulates CDC25B-dependent mitosis entry | Q63253113 | ||
| CDC5 and CKII control adaptation to the yeast DNA damage checkpoint | Q73763022 | ||
| Development of a substrate-based cyclic phosphopeptide inhibitor of protein phosphatase 2Cdelta, Wip1 | Q79315717 | ||
| The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1 | Q79754843 | ||
| Oncogenic phosphatase Wip1 is a novel prognostic marker for lung adenocarcinoma patient survival | Q83330999 | ||
| Genomic analysis reveals the molecular heterogeneity of ovarian clear cell carcinomas | Q83630862 | ||
| Human claspin is required for replication checkpoint control | Q28206333 | ||
| Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23 | Q28218453 | ||
| Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity | Q28218469 | ||
| SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase | Q28234989 | ||
| Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25 | Q28247761 | ||
| Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216 | Q28247771 | ||
| Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress | Q28255529 | ||
| Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery | Q28260190 | ||
| A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM | Q28270543 | ||
| Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase | Q28283888 | ||
| Death by releasing the breaks: CHK1 inhibitors as cancer therapeutics | Q28298703 | ||
| A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint | Q28472643 | ||
| Rapid destruction of human Cdc25A in response to DNA damage | Q28611930 | ||
| Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems | Q29026493 | ||
| Requirement for p53 and p21 to sustain G2 arrest after DNA damage | Q29547667 | ||
| ATR: an essential regulator of genome integrity | Q29547883 | ||
| ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks | Q29614215 | ||
| Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage | Q29614218 | ||
| Chk1 and Chk2 kinases in checkpoint control and cancer | Q29617706 | ||
| A Phase 1 study of UCN-01 in combination with irinotecan in patients with resistant solid tumor malignancies | Q30431388 | ||
| The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis | Q30486781 | ||
| A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance | Q30502070 | ||
| Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage | Q31160033 | ||
| Topoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathway | Q33205671 | ||
| A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D. | Q33294239 | ||
| Site-specific phosphorylation dynamics of the nuclear proteome during the DNA damage response | Q33883063 | ||
| Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. | Q33886072 | ||
| The ups and downs of p53: understanding protein dynamics in single cells | Q33941653 | ||
| Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response | Q33994571 | ||
| p38 mitogen-activated protein kinase promotes cell survival in response to DNA damage but is not required for the G(2) DNA damage checkpoint in human cancer cells | Q34045669 | ||
| Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response | Q34075834 | ||
| Assembly and function of DNA double-strand break repair foci in mammalian cells | Q34146952 | ||
| Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription | Q34149479 | ||
| Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents | Q34188494 | ||
| Phosphatases in the cellular response to DNA damage. | Q34198570 | ||
| p53 post-translational modification: deregulated in tumorigenesis | Q34300569 | ||
| Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner | Q34324643 | ||
| Chk1 is haploinsufficient for multiple functions critical to tumor suppression | Q34334239 | ||
| Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells. | Q34414003 | ||
| Stimulus-dependent dynamics of p53 in single cells | Q35088876 | ||
| Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit | Q35131775 | ||
| Targeting the checkpoint kinases: chemosensitization versus chemoprotection | Q35679781 | ||
| MK-1775, a potent Wee1 inhibitor, synergizes with gemcitabine to achieve tumor regressions, selectively in p53-deficient pancreatic cancer xenografts | Q35839058 | ||
| Wip1-deficient mice are resistant to common cancer genes | Q35862684 | ||
| Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase | Q36228219 | ||
| DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity | Q36316482 | ||
| Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D | Q36326949 | ||
| Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition | Q36499146 | ||
| The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways. | Q36617172 | ||
| p27Kip1 stabilization is essential for the maintenance of cell cycle arrest in response to DNA damage. | Q36675905 | ||
| Pharmacologic activation of p53 by small-molecule MDM2 antagonists | Q36731603 | ||
| Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control | Q37081706 | ||
| CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors | Q37103465 | ||
| The roles of p27(Kip1) and DNA damage signalling in the chemotherapy-induced delayed cell cycle checkpoint | Q37293920 | ||
| p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint | Q37302277 | ||
| P433 | issue | 21 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2601-2613 | |
| P577 | publication date | 2011-10-03 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | Checkpoint control and cancer | |
| P478 | volume | 31 |
| Q61801042 | 12,23-Dione dammarane triterpenes from Gynostemma longipes and their muscle cell proliferation activities via activation of the AMPK pathway |
| Q28385679 | 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway |
| Q35625053 | A Model for p38MAPK-Induced Astrocyte Senescence |
| Q38795664 | A novel ATM-dependent checkpoint defect distinct from loss of function mutation promotes genomic instability in melanoma. |
| Q35847932 | A novelly synthesized phenanthroline derivative is a promising DNA-damaging anticancer agent inhibiting G1/S checkpoint transition and inducing cell apoptosis in cancer cells |
| Q38775360 | ATM/ATR-mediated phosphorylation of PALB2 promotes RAD51 function. |
| Q38700525 | ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration. |
| Q47965335 | ATP-binding cassette transporters limit the brain penetration of Wee1 inhibitors |
| Q36242619 | Ailanthone Inhibits Huh7 Cancer Cell Growth via Cell Cycle Arrest and Apoptosis In Vitro and In Vivo |
| Q33557795 | And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance |
| Q92454665 | Anti-Proliferative and Pro-Apoptotic Effects of Licochalcone A through ROS-Mediated Cell Cycle Arrest and Apoptosis in Human Bladder Cancer Cells |
| Q37126186 | BRCA1 downregulates the kinase activity of Polo-like kinase 1 in response to replication stress |
| Q36121000 | Bmi-1: At the crossroads of physiological and pathological biology |
| Q22242276 | Cancer genome landscapes |
| Q28066868 | Cancer's Achilles' Heel: Apoptosis and Necroptosis to the Rescue |
| Q33753714 | Cancer-FOXP3 directly activated CCL5 to recruit FOXP3+Treg cells in pancreatic ductal adenocarcinoma |
| Q27011729 | Cell cycle progression by the repression of primary cilia formation in proliferating cells |
| Q34487607 | Coordinated regulation of XPA stability by ATR and HERC2 during nucleotide excision repair |
| Q38793178 | Cytokinetic effects of Wee1 disruption in pancreatic cancer. |
| Q26779054 | DDX3, a potential target for cancer treatment |
| Q35941085 | DNA Damage and Repair Biomarkers in Cervical Cancer Patients Treated with Neoadjuvant Chemotherapy: An Exploratory Analysis |
| Q38120311 | DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma. |
| Q40794273 | Defective cell cycle checkpoints as targets for anti-cancer therapies |
| Q48808585 | Dihydrocelastrol inhibits multiple myeloma cell proliferation and promotes apoptosis through ERK1/2 and IL-6/STAT3 pathways in vitro and in vivo. |
| Q39987364 | Down regulation of Chk1 by p53 plays a role in synergistic induction of apoptosis by chemotherapeutics and inhibitors for Jak2 or BCR/ABL in hematopoietic cells. |
| Q54969815 | Etoposide-induced DNA damage affects multiple cellular pathways in addition to DNA damage response. |
| Q42199612 | Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency |
| Q42777918 | Exposure to 4100K fluorescent light elicits sex specific transcriptional responses in Xiphophorus maculatus skin. |
| Q36841814 | Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint |
| Q47115561 | Geminin deficiency enhances survival in a murine medulloblastoma model by inducing apoptosis of preneoplastic granule neuron precursors |
| Q37158051 | Genetic causes of microcephaly and lessons for neuronal development |
| Q34564108 | Genistein abrogates G2 arrest induced by curcumin in p53 deficient T47D cells |
| Q39186453 | HIF1-regulated ATRIP expression is required for hypoxia induced ATR activation |
| Q34701793 | Hepatitis C virus NS2 protein inhibits DNA damage pathway by sequestering p53 to the cytoplasm. |
| Q92784061 | Induction of G2/M Cell Cycle Arrest and Apoptosis by Genistein in Human Bladder Cancer T24 Cells through Inhibition of the ROS-Dependent PI3k/Akt Signal Transduction Pathway |
| Q35048469 | Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhances induction of apoptosis. |
| Q90567138 | Isorhamnetin Induces Cell Cycle Arrest and Apoptosis Via Reactive Oxygen Species-Mediated AMP-Activated Protein Kinase Signaling Pathway Activation in Human Bladder Cancer Cells |
| Q38023979 | Maintenance of genomic integrity after DNA double strand breaks in the human prostate and seminal vesicle epithelium: the best and the worst |
| Q37099799 | Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells |
| Q42368992 | MicroRNA-16 feedback loop with p53 and Wip1 can regulate cell fate determination between apoptosis and senescence in DNA damage response. |
| Q38085906 | MicroRNAs in the ionizing radiation response and in radiotherapy |
| Q26801435 | MicroRNAs, cancer and ionizing radiation: Where are we? |
| Q36877040 | Mitochondria and familial predisposition to breast cancer |
| Q35540742 | Modelling the onset of senescence at the G1/S cell cycle checkpoint |
| Q28262425 | Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy? |
| Q37118895 | Opportunities for Radiosensitization in the Stereotactic Body Radiation Therapy (SBRT) Era |
| Q99710773 | PIK3R3 inhibits cell senescence through p53/p21 signaling |
| Q38223676 | Pathways for genome integrity in G2 phase of the cell cycle |
| Q38784376 | Physalin A induces G2/M phase cell cycle arrest in human non-small cell lung cancer cells: involvement of the p38 MAPK/ROS pathway |
| Q38917984 | Polo-like kinase 1 inhibits DNA damage response during mitosis |
| Q37718268 | Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication |
| Q37676851 | Proteomics insights into DNA damage response and translating this knowledge to clinical strategies |
| Q47371096 | Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases. |
| Q47289183 | Saikosaponin-d, a calcium mobilizing agent, sensitizes chemoresistant ovarian cancer cells to cisplatin-induced apoptosis by facilitating mitochondrial fission and G2/M arrest |
| Q38082328 | Senescence and aging: the critical roles of p53. |
| Q92208793 | Silencing of heat shock protein 27 increases the radiosensitivity of non‑small cell lung carcinoma cells |
| Q28550735 | Study of Malformin C, a Fungal Source Cyclic Pentapeptide, as an Anti-Cancer Drug |
| Q39036074 | Sulforaphane induces DNA damage and mitotic abnormalities in human osteosarcoma MG-63 cells: correlation with cell cycle arrest and apoptosis |
| Q41239908 | Targeting MicroRNAs in Prostate Cancer Radiotherapy |
| Q26771812 | Targeting New Candidate Genes by Small Molecules Approaching Neurodegenerative Diseases |
| Q26795781 | Targeting the Checkpoint to Kill Cancer Cells |
| Q35165148 | The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest. |
| Q42231430 | The G2 checkpoint-a node-based molecular switch |
| Q46259505 | The Translationally Controlled Tumor Protein and the Cellular Response to Ionizing Radiation-Induced DNA Damage |
| Q38796786 | The downregulation of the RNA-binding protein Staufen2 in response to DNA damage promotes apoptosis |
| Q38060522 | The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond. |
| Q38331206 | The role of DNA damage responses in p53 biology |
| Q64914085 | Tissue-specific and exosomal miRNAs in lung cancer radiotherapy: from regulatory mechanisms to clinical implications. |
| Q26745686 | Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy |
| Q48258080 | Troxerutin with copper generates oxidative stress in cancer cells: Its possible chemotherapeutic mechanism against hepatocellular carcinoma |
| Q99414093 | Truncated PPM1D Prevents Apoptosis in the Murine Thymus and Promotes Ionizing Radiation-Induced Lymphoma |
| Q42786047 | Tumor Protein p63/microRNA Network in Epithelial Cancer Cells |
| Q47301297 | UHRF1 is an Independent Prognostic Factor and a Potential Therapeutic Target of Esophageal Squamous Cell Carcinoma |
| Q34592732 | USP17- and SCFβTrCP--regulated degradation of DEC1 controls the DNA damage response |
| Q91645670 | p53 Isoforms in Cellular Senescence- and Ageing-Associated Biological and Physiological Functions |
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