| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.MOLCEL.2006.06.013 |
| P8608 | Fatcat ID | release_ulkiehnxijfmlcnij3s6z5b35e |
| P3181 | OpenCitations bibliographic resource ID | 100889 |
| P698 | PubMed publication ID | 16885022 |
| P5875 | ResearchGate publication ID | 6901843 |
| P50 | author | Michele Pagano | Q28357961 |
| Daniele Guardavaccaro | Q28358019 | ||
| Nicholas E. Sherman | Q37384140 | ||
| Angelo Peschiaroli | Q42839351 | ||
| Nicolino Valerio Dorrello | Q88917361 | ||
| P2093 | author name string | Monica Venere | |
| Thanos Halazonetis | |||
| P2860 | cites work | Identification of a family of human F-box proteins | Q22010703 |
| A family of mammalian F-box proteins | Q22010704 | ||
| Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome | Q24293506 | ||
| The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1 | Q24302164 | ||
| Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase | Q24304123 | ||
| Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase | Q24306203 | ||
| Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1 | Q24306531 | ||
| M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP | Q24329203 | ||
| PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints | Q24527393 | ||
| Systematic analysis and nomenclature of mammalian F-box proteins | Q24561715 | ||
| Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation | Q24564847 | ||
| Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression | Q24685645 | ||
| Mrc1 transduces signals of DNA replication stress to activate Rad53 | Q27935521 | ||
| Function and regulation of cullin-RING ubiquitin ligases | Q28131707 | ||
| Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts | Q28138471 | ||
| Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo | Q28177348 | ||
| Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage | Q28182301 | ||
| Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1 | Q28204894 | ||
| Human claspin is required for replication checkpoint control | Q28206333 | ||
| Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100 | Q28216699 | ||
| SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase | Q28234989 | ||
| Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase | Q28249846 | ||
| Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress | Q28255529 | ||
| ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage | Q28266407 | ||
| Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures | Q28269457 | ||
| Claspin, a regulator of Chk1 in DNA replication stress pathway | Q28274299 | ||
| The SCF ubiquitin ligase: insights into a molecular machine | Q28279993 | ||
| Chk1 is required to maintain claspin stability | Q28299260 | ||
| Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation | Q28587532 | ||
| Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation | Q28609667 | ||
| Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability | Q28612074 | ||
| Stabilizers and Destabilizers Controlling Cell Cycle Oscillators | Q29028448 | ||
| Chk1 and Chk2 kinases in checkpoint control and cancer | Q29617706 | ||
| Ubiquitin ligases: cell-cycle control and cancer | Q29617992 | ||
| Recycling the Cell Cycle | Q29999767 | ||
| Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17. | Q31134206 | ||
| Positive regulation of Wee1 by Chk1 and 14-3-3 proteins | Q33938220 | ||
| Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase | Q33968405 | ||
| Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response | Q34099551 | ||
| A unified view of the DNA-damage checkpoint | Q34560932 | ||
| Wagging the dogma; tissue-specific cell cycle control in the mouse embryo. | Q35875804 | ||
| Checking on DNA damage in S phase | Q35906070 | ||
| Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53. | Q35966662 | ||
| Structure and function of Polo-like kinases | Q36004636 | ||
| Getting in and out of mitosis with Polo-like kinase-1. | Q36101754 | ||
| SCF-mediated protein degradation and cell cycle control | Q36101758 | ||
| The S phase checkpoint: when the crowd meets at the fork | Q36102436 | ||
| Restarting the cell cycle when the checkpoint comes to a halt | Q36231461 | ||
| Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage | Q36701199 | ||
| Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway. | Q40378903 | ||
| Checkpoint adaptation and recovery: back with Polo after the break | Q40502498 | ||
| Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells | Q40518897 | ||
| Pocket protein complexes are recruited to distinct targets in quiescent and proliferating cells | Q42537499 | ||
| Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion. | Q43714118 | ||
| Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase | Q44910791 | ||
| Identification of novel E2F1 target genes regulated in cell cycle-dependent and independent manners | Q53649151 | ||
| Polo-like kinase-1 is a target of the DNA damage checkpoint | Q57985159 | ||
| Cdk1: the dominant sibling of Cdk2 | Q80964932 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | positive regulation of proteolysis | Q14907134 |
| F-box and WD repeat domain containing 11 | Q21115408 | ||
| Beta-transducin repeat containing E3 ubiquitin protein ligase | Q21116841 | ||
| Polo like kinase 1 | Q21131841 | ||
| Claspin | Q21173220 | ||
| P304 | page(s) | 319-29 | |
| P577 | publication date | 2006-08-04 | |
| P1433 | published in | Molecular Cell | Q3319468 |
| P1476 | title | SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response | |
| P478 | volume | 23 |
| Q37938398 | 14-3-3 proteins as signaling integration points for cell cycle control and apoptosis |
| Q28472643 | A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint |
| Q41712580 | A new layer of degradation mechanism for PR-Set7/Set8 during cell cycle |
| Q41807438 | A novel role for greatwall kinase in recovery from DNA damage |
| Q36460381 | A stringent requirement for Plk1 T210 phosphorylation during K-fiber assembly and chromosome congression |
| Q57666020 | A systems-wide screen identifies substrates of the SCF TrCP ubiquitin ligase |
| Q41127007 | APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase |
| Q37245199 | APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. |
| Q24312475 | ATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage response |
| Q38700525 | ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration. |
| Q41971846 | ATR signaling at a glance |
| Q43097731 | Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1. |
| Q37375249 | Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity |
| Q37258462 | Artemis regulates cell cycle recovery from the S phase checkpoint by promoting degradation of cyclin E. |
| Q33635896 | Ataxin-3 promotes genome integrity by stabilizing Chk1. |
| Q36039180 | Aurora-A expressing tumour cells are deficient for homology-directed DNA double strand-break repair and sensitive to PARP inhibition |
| Q92320326 | Basal CHK1 activity safeguards its stability to maintain intrinsic S-phase checkpoint functions |
| Q33528933 | CDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptation |
| Q38015388 | CRL Ubiquitin Ligases and DNA Damage Response |
| Q46847087 | Cdc7 kinase mediates Claspin phosphorylation in DNA replication checkpoint |
| Q36923333 | Cdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpoint |
| Q37262174 | Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways |
| Q38891869 | Central Role of Ubiquitination in Genome Maintenance: DNA Replication and Damage Repair |
| Q36769867 | Checkpoint adaptation in human cells |
| Q37941374 | Checkpoint control and cancer. |
| Q48250645 | Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis. |
| Q24306163 | Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancer |
| Q39855660 | Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity. |
| Q94452061 | Chk1-mediated phosphorylation of Cdh1 promotes the SCFβTRCP-dependent degradation of Cdh1 during S-phase and efficient cell-cycle progression |
| Q53330219 | Chk2 is required for optimal mitotic delay in response to irradiation-induced DNA damage incurred in G2 phase. |
| Q54942210 | Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy. |
| Q80151856 | Cleavage and degradation of Claspin during apoptosis by caspases and the proteasome |
| Q39972799 | Cleavage-mediated activation of Chk1 during apoptosis |
| Q39161686 | Comparative phosphoproteomic analysis of checkpoint recovery identifies new regulators of the DNA damage response. |
| Q64064337 | Comparative transcriptome analysis reveals potential evolutionary differences in adaptation of temperature and body shape among four Percidae species |
| Q58708548 | Control of DNA Replication Initiation by Ubiquitin |
| Q24647543 | Control of cell growth by the SCF and APC/C ubiquitin ligases |
| Q28273354 | Control of chromosome stability by the beta-TrCP-REST-Mad2 axis |
| Q37267450 | Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress |
| Q34365216 | Cullins and Cancer |
| Q35668793 | DNA Damage Regulates Translation through β-TRCP Targeting of CReP |
| Q64078921 | DNA Damage Stress: Cui Prodest? |
| Q38405830 | DNA damage checkpoint recovery and cancer development |
| Q28083686 | DNA damage control: regulation and functions of checkpoint kinase 1 |
| Q38707053 | DNA replication stress: from molecular mechanisms to human disease |
| Q42125812 | Defective DNA repair increases susceptibility to senescence through extension of Chk1-mediated G2 checkpoint activation |
| Q42291803 | Degradation of Mrc1 promotes recombination-mediated restart of stalled replication forks |
| Q24648025 | Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer |
| Q34733221 | Diggin' on u(biquitin): a novel method for the identification of physiological E3 ubiquitin ligase substrates. |
| Q37579636 | Dissecting the role of ubiquitylation in the DNA damage response checkpoint in G2. |
| Q50036793 | Doxorubicin-induced DNA damage causes extensive ubiquitination of ribosomal proteins associated with a decrease in protein translation. |
| Q33526233 | Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway |
| Q39271396 | Enzyme-substrate relationships in the ubiquitin system: approaches for identifying substrates of ubiquitin ligases |
| Q26785368 | F-box protein interactions with the hallmark pathways in cancer |
| Q38719694 | FEM1 proteins are ancient regulators of SLBP degradation |
| Q99604819 | FRET-Based Sorting of Live Cells Reveals Shifted Balance between PLK1 and CDK1 Activities During Checkpoint Recovery |
| Q40021835 | G2/M checkpoint stringency is a key parameter in the sensitivity of AML cells to genotoxic stress. |
| Q92290872 | GSK3-β Stimulates Claspin Degradation via β-TrCP Ubiquitin Ligase and Alters Cancer Cell Survival |
| Q35309803 | Greatwall and Polo-like Kinase 1 Coordinate to Promote Checkpoint Recovery |
| Q34579692 | HERC2-USP20 axis regulates DNA damage checkpoint through Claspin |
| Q39750898 | Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation |
| Q89995052 | How Cells Handle DNA Breaks during Mitosis: Detection, Signaling, Repair, and Fate Choice |
| Q42544432 | Human papillomavirus 16 E7 oncoprotein attenuates DNA damage checkpoint control by increasing the proteolytic turnover of claspin |
| Q34148484 | IKK and NF-kappaB-mediated regulation of Claspin impacts on ATR checkpoint function |
| Q35056261 | Illumination of mitotic orchestra during cell division: a Polo view |
| Q35207086 | Inactivating UBE2M impacts the DNA damage response and genome integrity involving multiple cullin ligases |
| Q38741827 | Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora. |
| Q39710967 | Inhibition of gliomagenesis and attenuation of mitotic transition by MIIP. |
| Q26740196 | Insights into APC/C: from cellular function to diseases and therapeutics |
| Q51643575 | Integrated computational model of cell cycle and checkpoint reveals different essential roles of Aurora-A and Plk1 in mitotic entry |
| Q39574453 | Interactions between Swi1-Swi3, Mrc1 and S phase kinase, Hsk1 may regulate cellular responses to stalled replication forks in fission yeast |
| Q38999863 | Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase |
| Q36917433 | It takes two to tango: Ubiquitin and SUMO in the DNA damage response |
| Q34804030 | Ku80 removal from DNA through double strand break-induced ubiquitylation |
| Q35031397 | Loss of autophagy causes a synthetic lethal deficiency in DNA repair. |
| Q36247756 | MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage |
| Q55085725 | Maintain Genomic Stability: Multitask of DNA Replication Proteins. |
| Q37826346 | Molecular Mechanisms of Ultraviolet Radiation‐Induced DNA Damage and Repair |
| Q26775592 | Motif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulation |
| Q37819727 | Multiple Functions of the S-Phase Checkpoint Mediator |
| Q36598338 | Nek1 kinase associates with ATR–ATRIP and primes ATR for efficient DNA damage signaling |
| Q28262425 | Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy? |
| Q24298764 | Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal |
| Q64251963 | On the Interplay of the DNA Replication Program and the Intra-S Phase Checkpoint Pathway |
| Q35641483 | Onset of the DNA replication checkpoint in the early Drosophila embryo |
| Q94464887 | P53 suppresses SENP3 phosphorylation to mediate G2 checkpoint |
| Q64388990 | PLK1 targets CtIP to promote microhomology-mediated end joining |
| Q56798186 | Phosphatase Type 2A-dependent and -independent Pathways for ATR Phosphorylation of Chk1 |
| Q28297156 | Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response |
| Q24295177 | Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase |
| Q28115063 | Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression |
| Q53507575 | Plk1-dependent phosphorylation regulates functions of DNA topoisomerase IIalpha in cell cycle progression |
| Q36491053 | Plx1 is required for chromosomal DNA replication under stressful conditions |
| Q34144573 | Polo-like kinase 1 activated by the hepatitis B virus X protein attenuates both the DNA damage checkpoint and DNA repair resulting in partial polyploidy |
| Q21090068 | Polo-like kinase-1 controls Aurora A destruction by activating APC/C-Cdh1 |
| Q37874019 | Polo-like kinases and DNA damage checkpoint: beyond the traditional mitotic functions |
| Q89838203 | Posttranscriptional control of the replication stress response via TTP-mediated Claspin mRNA stabilization |
| Q34363725 | Prevalence and functional analysis of sequence variants in the ATR checkpoint mediator Claspin |
| Q38268314 | Proteasome-dependent degradation of transcription factor activating enhancer-binding protein 4 (TFAP4) controls mitotic division |
| Q24307983 | Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress |
| Q37271812 | RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells |
| Q39251898 | RSK promotes G2 DNA damage checkpoint silencing and participates in melanoma chemoresistance |
| Q34467504 | Ras regulates SCF(β-TrCP) protein activity and specificity via its effector protein NORE1A. |
| Q28073260 | Recovery from the DNA Replication Checkpoint |
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| Q34949214 | Regulation of DNA damage response pathways by the cullin-RING ubiquitin ligases |
| Q37088926 | Regulation of DNA repair throughout the cell cycle |
| Q37995680 | Regulation of NF‐κB by ubiquitination and degradation of the IκBs |
| Q36189395 | Regulation of polo-like kinase 1 by DNA damage and PP2A/B55α |
| Q28577634 | Regulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons |
| Q24302160 | Repeated phosphopeptide motifs in human Claspin are phosphorylated by Chk1 and mediate Claspin function |
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| Q38768033 | SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development. |
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| Q39145490 | Src family kinases promote silencing of ATR-Chk1 signaling in termination of DNA damage checkpoint |
| Q41039086 | Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP. |
| Q34968474 | Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase |
| Q35803109 | TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response |
| Q37497709 | Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response |
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| Q35195010 | The ATR signaling pathway is disabled during infection with the parvovirus minute virus of mice |
| Q37875478 | The BRCA1 ubiquitin ligase and homologous recombination repair |
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| Q39159931 | The Role of the Transcriptional Response to DNA Replication Stress. |
| Q37562004 | The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis. |
| Q36596489 | The Saccharomyces cerevisiae F-Box Protein Dia2 Is a Mediator of S-Phase Checkpoint Recovery from DNA Damage |
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