| scholarly article | Q13442814 |
| P50 | author | Daniel Durocher | Q28324139 |
| P2093 | author name string | Sarah Galicia | |
| David P Toczyski | |||
| Genevieve M Vidanes | |||
| Stephanie Cheung | |||
| Frédéric D Sweeney | |||
| John P Doyle | |||
| P2860 | cites work | Targeting polo-like kinase 1 for cancer therapy. | Q53348000 |
| Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation. | Q53662825 | ||
| Polo-like kinase-1 is a target of the DNA damage checkpoint | Q57985159 | ||
| Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways | Q58883742 | ||
| The BRCT domain of the S. cerevisiae checkpoint protein Rad9 mediates a Rad9-Rad9 interaction after DNA damage | Q64131921 | ||
| Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms | Q64388006 | ||
| A DNA damage response pathway controlled by Tel1 and the Mre11 complex | Q64388109 | ||
| Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms | Q73153090 | ||
| FHA domain-mediated DNA checkpoint regulation of Rad53 | Q73636844 | ||
| CDC5 and CKII control adaptation to the yeast DNA damage checkpoint | Q73763022 | ||
| MEC1-dependent phosphorylation of Rad9p in response to DNA damage | Q77231583 | ||
| DNA degradation at unprotected telomeres in yeast is regulated by the CDK1 (Cdc28/Clb) cell-cycle kinase | Q79181380 | ||
| SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response | Q24298620 | ||
| Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody | Q24337413 | ||
| An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing | Q24541493 | ||
| Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro | Q24550745 | ||
| Replication protein A-mediated recruitment and activation of Rad17 complexes | Q24631467 | ||
| Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA | Q24806674 | ||
| The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms | Q27628846 | ||
| The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain | Q27642308 | ||
| Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes | Q27860662 | ||
| Mdt1, a novel Rad53 FHA1 domain-interacting protein, modulates DNA damage tolerance and G(2)/M cell cycle progression in Saccharomyces cerevisiae. | Q27930637 | ||
| Mrc1 transduces signals of DNA replication stress to activate Rad53. | Q27935521 | ||
| Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint | Q27935742 | ||
| Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint | Q27937738 | ||
| DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1 | Q27938100 | ||
| Cdc5 interacts with the Wee1 kinase in budding yeast | Q27938383 | ||
| Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress | Q28255529 | ||
| Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery | Q28260190 | ||
| The DNA damage response: ten years after | Q28261230 | ||
| Cell-cycle checkpoints and cancer | Q28293996 | ||
| ATR: an essential regulator of genome integrity | Q29547883 | ||
| ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks | Q29614215 | ||
| Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins | Q29615270 | ||
| Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways | Q29615271 | ||
| Polo-like kinases and the orchestration of cell division | Q29616759 | ||
| Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest. | Q30657462 | ||
| The FHA domain is a modular phosphopeptide recognition motif. | Q33285631 | ||
| Concerted mechanism of Swe1/Wee1 regulation by multiple kinases in budding yeast. | Q33854145 | ||
| Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage | Q33888520 | ||
| Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast | Q33948005 | ||
| Maintenance of the DNA-damage checkpoint requires DNA-damage-induced mediator protein oligomerization | Q34369429 | ||
| A unified view of the DNA-damage checkpoint | Q34560932 | ||
| Two checkpoint complexes are independently recruited to sites of DNA damage in vivo | Q35082282 | ||
| A novel replication arrest pathway in response to DNA damage | Q35623742 | ||
| The Polo-box domain: a molecular integrator of mitotic kinase cascades and Polo-like kinase function | Q35623747 | ||
| Polo-like kinases (Plks) and cancer | Q36004649 | ||
| A coupled chemical-genetic and bioinformatic approach to Polo-like kinase pathway exploration. | Q36408265 | ||
| The role of the polo kinase Cdc5 in controlling Cdc14 localization | Q37155259 | ||
| Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1. | Q37162736 | ||
| Checkpoint adaptation precedes spontaneous and damage-induced genomic instability in yeast | Q39457935 | ||
| EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants | Q39860143 | ||
| A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1. | Q40419083 | ||
| A Ddc2-Rad53 fusion protein can bypass the requirements for RAD9 and MRC1 in Rad53 activation | Q40522020 | ||
| Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation | Q40653881 | ||
| The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage | Q41854894 | ||
| Two-stage mechanism for activation of the DNA replication checkpoint kinase Cds1 in fission yeast | Q42424667 | ||
| Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase. | Q42687620 | ||
| Mechanisms of checkpoint kinase Rad53 inactivation after a double-strand break in Saccharomyces cerevisiae | Q42738072 | ||
| Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. | Q43711748 | ||
| Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion. | Q43714118 | ||
| PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break | Q44384534 | ||
| A domain of Rad9 specifically required for activation of Chk1 in budding yeast | Q44717404 | ||
| Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase | Q44910791 | ||
| Cds1 phosphorylation by Rad3-Rad26 kinase is mediated by forkhead-associated domain interaction with Mrc1. | Q44918067 | ||
| Methods for studying adaptation to the DNA damage checkpoint in yeast. | Q46003721 | ||
| The Polo-related kinase Cdc5 activates and is destroyed by the mitotic cyclin destruction machinery in S. cerevisiae | Q46071697 | ||
| The Plk1 Polo box domain mediates a cell cycle and DNA damage regulated interaction with Chk2. | Q46474904 | ||
| Diverse but overlapping functions of the two forkhead-associated (FHA) domains in Rad53 checkpoint kinase activation | Q47834669 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ImageQuant | Q112270642 |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Chromatin-binding protein RAD9 YDR217C | Q27548439 |
| Polo kinase CDC5 YMR001C | Q27549209 | ||
| Serine/threonine/tyrosine protein kinase RAD53 YPL153C | Q27549441 | ||
| P304 | page(s) | e1000286 | |
| P577 | publication date | 2010-01-26 | |
| P1433 | published in | PLOS Biology | Q1771695 |
| P1476 | title | CDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptation | |
| P478 | volume | 8 |
| Q37938398 | 14-3-3 proteins as signaling integration points for cell cycle control and apoptosis |
| Q60309634 | Adaptation to DNA damage checkpoint in senescent telomerase-negative cells promotes genome instability |
| Q34659809 | Cdc5 blocks in vivo Rad53 activity, but not in situ activity (ISA) |
| Q24306163 | Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancer |
| Q39161686 | Comparative phosphoproteomic analysis of checkpoint recovery identifies new regulators of the DNA damage response. |
| Q64078921 | DNA Damage Stress: Cui Prodest? |
| Q36906226 | Dbf4: the whole is greater than the sum of its parts |
| Q37265011 | Deacetylase Rpd3 facilitates checkpoint adaptation by preventing Rad53 overactivation |
| Q37956184 | Eukaryotic DNA damage checkpoint activation in response to double-strand breaks |
| Q47997215 | Functions and regulation of the Polo-like kinase Cdc5 in the absence and presence of DNA damage. |
| Q38741827 | Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora. |
| Q27930771 | Inhibition of the mitotic exit network in response to damaged telomeres. |
| Q35390092 | Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast |
| Q42106809 | Multiplexed Imaging of Protein Phosphorylation on Membranes Based on Ti(IV) Functionalized Nanopolymers. |
| Q36210916 | Mus81-Mms4 functions as a single heterodimer to cleave nicked intermediates in recombinational DNA repair |
| Q34273948 | Pph3 dephosphorylation of Rad53 is required for cell recovery from MMS-induced DNA damage in Candida albicans |
| Q33649550 | Preserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance. |
| Q36780916 | RAD53 is limiting in double-strand break repair and in protection against toxicity associated with ribonucleotide reductase inhibition |
| Q37546864 | Rad53 downregulates mitotic gene transcription by inhibiting the transcriptional activator Ndd1. |
| Q39450140 | Reduced kinase activity of polo kinase Cdc5 affects chromosome stability and DNA damage response in S. cerevisiae. |
| Q89719971 | Regulation of Mitotic Exit by Cell Cycle Checkpoints: Lessons From Saccharomyces cerevisiae |
| Q41789965 | Replication checkpoint: tuning and coordination of replication forks in s phase |
| Q34100969 | SCF(FBXW7α) modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stability |
| Q33563324 | The budding yeast Polo-like kinase localizes to distinct populations at centrosomes during mitosis |
| Q38394869 | The budding yeast polo-like kinase Cdc5 regulates the Ndt80 branch of the meiotic recombination checkpoint pathway. |
| Q30596955 | The subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3: dynamics and interdependence |
| Q37809415 | Type 2C protein phosphatases in fungi |
| Q27931778 | Use of quantitative mass spectrometric analysis to elucidate the mechanisms of phospho-priming and auto-activation of the checkpoint kinase Rad53 in vivo |
| Q38241194 | When genome integrity and cell cycle decisions collide: roles of polo kinases in cellular adaptation to DNA damage |
Search more.