| scholarly article | Q13442814 |
| P50 | author | Ora Schueler-Furman | Q47566985 |
| Nir London | Q56441722 | ||
| Naama Kanarek | Q59556192 | ||
| P2093 | author name string | Yinon Ben-Neriah | |
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| Identification of the receptor component of the IkappaBalpha-ubiquitin ligase | Q22008569 | ||
| IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex | Q22254561 | ||
| NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100 | Q24290908 | ||
| IkappaBepsilon-deficient mice: reduction of one T cell precursor subspecies and enhanced Ig isotype switching and cytokine synthesis | Q62907266 | ||
| The 90-kDa Ribosomal S6 Kinase (pp90rsk) Phosphorylates the N-terminal Regulatory Domain of IκBα and Stimulates Its Degradation in Vitro | Q73596199 | ||
| High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-kappaB activation | Q73766164 | ||
| Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor | Q73958568 | ||
| The kinetics of association and phosphorylation of IkappaB isoforms by IkappaB kinase 2 correlate with their cellular regulation in human endothelial cells | Q77730547 | ||
| Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway | Q40830298 | ||
| Common pathway for the ubiquitination of IkappaBalpha, IkappaBbeta, and IkappaBepsilon mediated by the F-box protein FWD1. | Q40927249 | ||
| The precursor of NF-kappa B p50 has I kappa B-like functions | Q41598400 | ||
| UV as an amplifier rather than inducer of NF-kappaB activity | Q41891688 | ||
| Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase | Q42631679 | ||
| The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms | Q42808605 | ||
| Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothe cin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-kappaB activation | Q43492346 | ||
| Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB. | Q43584710 | ||
| Overexpression of human beta TrCP1 deleted of its F box induces tumorigenesis in transgenic mice | Q45286163 | ||
| The processivity of multiubiquitination by the APC determines the order of substrate degradation. | Q45345067 | ||
| Proteolysis of NF-kappaB1 p105 is essential for T cell antigen receptor-induced proliferation | Q46211455 | ||
| CK2 Is a C-Terminal IκB Kinase Responsible for NF-κB Activation during the UV Response | Q46589615 | ||
| p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction | Q46602560 | ||
| Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb | Q47070747 | ||
| New insights into NF-kappaB regulation and function | Q47097632 | ||
| HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin | Q47965199 | ||
| The COP9 Signalosome | Q51111655 | ||
| Modification by single ubiquitin moieties rather than polyubiquitination is sufficient for proteasomal processing of the p105 NF-kappaB precursor | Q51793392 | ||
| Generation of p50 subunit of NF-kappa B by processing of p105 through an ATP-dependent pathway | Q54071596 | ||
| Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein | Q24291288 | ||
| Multiple nuclear factors interact with the immunoglobulin enhancer sequences | Q24296245 | ||
| SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response | Q24298620 | ||
| A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response | Q24299489 | ||
| Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition | Q24305416 | ||
| Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase | Q24306203 | ||
| The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint | Q24317772 | ||
| I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity | Q24318573 | ||
| NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway | Q24321670 | ||
| M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP | Q24329203 | ||
| NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases | Q24337709 | ||
| Ikappa Balpha is a target for the mitogen-activated 90kDa ribosomal S6 kinase | Q24532221 | ||
| NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes | Q24534356 | ||
| Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha | Q24548385 | ||
| The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro | Q24608829 | ||
| Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U | Q24672630 | ||
| A fourth IkappaB protein within the NF-kappaB signaling module | Q24676472 | ||
| SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase | Q24685556 | ||
| Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity | Q27860643 | ||
| Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation | Q27860876 | ||
| F-Box Proteins Are Receptors that Recruit Phosphorylated Substrates to the SCF Ubiquitin-Ligase Complex | Q27934075 | ||
| SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box | Q27936367 | ||
| A Complex of Cdc4p, Skp1p, and Cdc53p/Cullin Catalyzes Ubiquitination of the Phosphorylated CDK Inhibitor Sic1p | Q27939049 | ||
| Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. | Q27940059 | ||
| betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932. | Q28118570 | ||
| Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha | Q28143121 | ||
| The WD repeat: a common architecture for diverse functions | Q28143827 | ||
| beta-TrCP mediates the signal-induced ubiquitination of IkappaBbeta | Q28145644 | ||
| The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kappa B-mediated inhibition | Q28155838 | ||
| Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo | Q28177348 | ||
| Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage | Q28182301 | ||
| Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome | Q28187304 | ||
| The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases? | Q28188435 | ||
| Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses | Q28199204 | ||
| The leucine-rich repeat as a protein recognition motif | Q28212461 | ||
| Duration of nuclear NF-kappaB action regulated by reversible acetylation | Q28215080 | ||
| E3 ubiquitin ligase that recognizes sugar chains | Q28215953 | ||
| Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100 | Q28216699 | ||
| Lymphotoxin beta receptor induces interleukin 8 gene expression via NF-kappaB and AP-1 activation | Q28217253 | ||
| Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases | Q28239642 | ||
| Regulation of the cell cycle by SCF-type ubiquitin ligases | Q28245984 | ||
| The SCF ubiquitin ligase: insights into a molecular machine | Q28279993 | ||
| Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate | Q28280916 | ||
| Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains | Q28590989 | ||
| Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor | Q28615489 | ||
| Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway | Q28615591 | ||
| Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination | Q28615601 | ||
| Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway | Q28615706 | ||
| Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B | Q28615823 | ||
| Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation | Q28776205 | ||
| SCF and Cullin/Ring H2-based ubiquitin ligases | Q29547637 | ||
| NF-kappaB functions as a tumour promoter in inflammation-associated cancer | Q29614598 | ||
| Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation | Q29614709 | ||
| Macromolecular modeling with rosetta | Q29615856 | ||
| An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer | Q29616732 | ||
| The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation | Q29617813 | ||
| Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B | Q29618193 | ||
| The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B | Q29618194 | ||
| Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B | Q29618210 | ||
| SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting | Q29619527 | ||
| Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism | Q29619866 | ||
| Introducing spatial information into predictive NF-kappaB modelling--an agent-based approach | Q33340241 | ||
| Direct association and nuclear import of the hepatitis B virus X protein with the NF-kappaB inhibitor IkappaBalpha | Q33959538 | ||
| Constitutive phosphorylation of I kappa B alpha by casein kinase II | Q33994452 | ||
| NF-kappa B as a therapeutic target in multiple myeloma | Q34521393 | ||
| Proteasome inhibition: a novel approach to cancer therapy | Q34583900 | ||
| NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions. | Q34720640 | ||
| Proteolytic degradation of MAD3 (I kappa B alpha) and enhanced processing of the NF-kappa B precursor p105 are obligatory steps in the activation of NF-kappa B. | Q35019615 | ||
| You Wnt some, you lose some: oncogenes in the Wnt signaling pathway | Q35062431 | ||
| The many faces of beta-TrCP E3 ubiquitin ligases: reflections in the magic mirror of cancer | Q35691542 | ||
| A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency | Q36001303 | ||
| Proteasome inhibition as a novel therapeutic target in human cancer. | Q36014046 | ||
| Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. | Q36155317 | ||
| Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha | Q36180990 | ||
| Functional redundancy of the nuclear factor kappa B inhibitors I kappa B alpha and I kappa B beta | Q36401827 | ||
| The same IkappaBalpha mutation in two related individuals leads to completely different clinical syndromes. | Q36402422 | ||
| The nuclear ubiquitin-proteasome system | Q36474620 | ||
| In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa B | Q36549755 | ||
| Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B. | Q36551014 | ||
| Many faces of NF-kappaB signaling induced by genotoxic stress | Q36868559 | ||
| Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma | Q37314736 | ||
| Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice | Q38289217 | ||
| Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family | Q38313406 | ||
| Understanding NF-kappaB signaling via mathematical modeling | Q39045822 | ||
| Postrepression activation of NF-kappaB requires the amino-terminal nuclear export signal specific to IkappaBalpha | Q39460041 | ||
| Transient IkappaB kinase activity mediates temporal NF-kappaB dynamics in response to a wide range of tumor necrosis factor-alpha doses | Q40345278 | ||
| Stimulus specificity of gene expression programs determined by temporal control of IKK activity | Q40372675 | ||
| Identification of positive and negative regulatory regions controlling expression of the Xenopus laevis betaTrCP gene | Q40537365 | ||
| Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation | Q40556549 | ||
| Inhibition of HOS expression and activities by Wnt pathway | Q40750211 | ||
| IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells | Q40778669 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | NF-κB | Q411114 |
| protein ubiquitination | Q3547638 | ||
| P304 | page(s) | a000166 | |
| P577 | publication date | 2010-02-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Cold Spring Harbor Perspectives in Biology | Q3927509 |
| P1476 | title | Ubiquitination and degradation of the inhibitors of NF-kappaB | |
| P478 | volume | 2 |
| Q35604264 | A three-part signal governs differential processing of Gli1 and Gli3 proteins by the proteasome |
| Q35027559 | A unique insertion in STARD9's motor domain regulates its stability |
| Q123351242 | Advanced in vitro models for renal cell carcinoma therapy design |
| Q35802588 | Alloferon Alleviates Dextran Sulfate Sodium-induced Colitis |
| Q90062344 | An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma |
| Q89921428 | Anti-Inflammatory and Anti-Oxidative Activity of Indole-3-Acetic Acid Involves Induction of HO-1 and Neutralization of Free Radicals in RAW264.7 Cells |
| Q47711197 | Anti-inflammatory effects of an ethanol extract of Aster glehni via inhibition of NF-κB activation in mice with DSS-induced colitis |
| Q37066084 | Cadmium and Secondary Structure-dependent Function of a Degron in the Pca1p Cadmium Exporter |
| Q42323974 | Chronic ingestion of alcohol modulates expression of ubiquitin editing enzyme A20 in lung macrophages |
| Q35989733 | Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer |
| Q33767779 | Coronavirus infection, ER stress, apoptosis and innate immunity |
| Q38259045 | Coronavirus-induced ER stress response and its involvement in regulation of coronavirus-host interactions |
| Q57039796 | Disruption of Chromosomal Architecture of cox2 Locus Sensitizes Lung Cancer Cells to Radiotherapy |
| Q39203753 | Double inhibition of NF-κB and XIAP via RNAi enhances the sensitivity of pancreatic cancer cells to gemcitabine |
| Q39361295 | Human IκBα Gain of Function: a Severe and Syndromic Immunodeficiency |
| Q36032171 | Impairment of T cell development and acute inflammatory response in HIV-1 Tat transgenic mice |
| Q26782894 | Implications of glial nitric oxide in neurodegenerative diseases |
| Q47221508 | Infection with Classical Swine Fever Virus Induces Expression of Type III Interferons and Activates Innate Immune Signaling |
| Q29620242 | Inflammation meets cancer, with NF-κB as the matchmaker |
| Q36250214 | Inhibition of p-IκBα Ubiquitylation by Autophagy-Related Gene 7 to Regulate Inflammatory Responses to Bacterial Infection |
| Q37995679 | It takes two to tango: IκBs, the multifunctional partners of NF-κB. |
| Q34544660 | Lack of effect of the Salmonella deubiquitinase SseL on the NF-κB pathway |
| Q37690966 | Lapatinib-induced NF-kappaB activation sensitizes triple-negative breast cancer cells to proteasome inhibitors |
| Q89701276 | Macrophages employ quorum licensing to regulate collective activation |
| Q34536269 | Molecular Mechanisms of Innate Immune Inhibition by Non-Segmented Negative-Sense RNA Viruses |
| Q38850050 | Mouse Cd59b but not Cd59a is upregulated to protect cells from complement attack in response to inflammatory stimulation |
| Q35763283 | Nitric oxide modulates sodium vitamin C transporter 2 (SVCT-2) protein expression via protein kinase G (PKG) and nuclear factor-κB (NF-κB). |
| Q37990496 | No one can whistle a symphony alone – how different ubiquitin linkages cooperate to orchestrate NF-κB activity |
| Q26778007 | Pathophysiological mechanisms of death resistance in colorectal carcinoma |
| Q90384118 | Proteasome Inhibitors Suppress ErbB Family Expression through HSP90-Mediated Lysosomal Degradation |
| Q37420038 | Protect and serve: Bcl-2 proteins as guardians and rulers of cancer cell survival. |
| Q42673758 | Proteome-wide analysis of human disease mutations in short linear motifs: neglected players in cancer? |
| Q35072342 | Putative E3 ubiquitin ligase of human rotavirus inhibits NF-κB activation by using molecular mimicry to target β-TrCP. |
| Q91105578 | RBBP6, a RING finger-domain E3 ubiquitin ligase, induces epithelial-mesenchymal transition and promotes metastasis of colorectal cancer |
| Q37995680 | Regulation of NF‐κB by ubiquitination and degradation of the IκBs |
| Q38289055 | Role of the ubiquitin proteasome system in hematologic malignancies. |
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| Q37980557 | Signaling in Innate Immunity and Inflammation |
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