| scholarly article | Q13442814 |
| P2093 | author name string | Sang-Min Jang | |
| Mirit I Aladjem | |||
| Christophe E Redon | |||
| P2860 | cites work | Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex | Q24294734 |
| CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity. | Q24296919 | ||
| SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response | Q24298620 | ||
| PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR | Q24300018 | ||
| An OBSL1-Cul7Fbxw8 Ubiquitin Ligase Signaling Mechanism Regulates Golgi Morphology and Dendrite Patterning | Q24302459 | ||
| Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1 | Q24303428 | ||
| Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase | Q24304123 | ||
| Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest | Q24304478 | ||
| Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1 | Q24306531 | ||
| The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses | Q24306576 | ||
| PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex | Q24312855 | ||
| Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression | Q24314416 | ||
| Overexpression of Rabl3 and Cullin7 is associated with pathogenesis and poor prognosis in hepatocellular carcinoma | Q50521041 | ||
| Regulation of nuclear transport and degradation of the Xenopus cyclin-dependent kinase inhibitor, p27Xic1. | Q50722198 | ||
| Radiosensitization of Human Colorectal Cancer Cells by MLN4924: An Inhibitor of NEDD8-Activating Enzyme | Q52936438 | ||
| Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2α through hypoxia- and von Hippel-Lindau tumor suppressor protein-independent regulatory mechanisms. | Q53221890 | ||
| Identification of a tumor suppressor network in T-cell leukemia | Q53536725 | ||
| SCFβ(TrCP) mediates stress-activated MAPK-induced Cdc25B degradation. | Q54570388 | ||
| Regulation of Mammalian DNA Replication via the Ubiquitin-Proteasome System. | Q55239552 | ||
| Downregulation of the KIP family members p27KIP1and p57KIP2by SKP2 and the role of methylation in p57KIP2inactivation in nonsmall cell lung cancer | Q58068576 | ||
| UV-induced degradation of securin is mediated by SKP1-CUL1- TrCP E3 ubiquitin ligase | Q63405954 | ||
| Regulating microtubules and genome stability via the CUL7/3M syndrome complex and CUL9 | Q88031099 | ||
| Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration | Q41045804 | ||
| Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target | Q41083946 | ||
| DDB1 and CUL4 associated factor 11 (DCAF11) mediates degradation of Stem-loop binding protein at the end of S phase | Q41819560 | ||
| CRL4CDT2 Targets CHK1 for PCNA-Independent Destruction | Q41840512 | ||
| Orc2 protects ORCA from ubiquitin-mediated degradation | Q41896926 | ||
| The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells | Q42054892 | ||
| Multiple Components of the VHL Tumor Suppressor Complex Are Frequently Affected by DNA Copy Number Loss in Pheochromocytoma | Q42101114 | ||
| pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4CRBN ubiquitin ligase | Q42101565 | ||
| Ubiquitylation of FACT by the cullin-E3 ligase Rtt101 connects FACT to DNA replication | Q42204697 | ||
| Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. | Q42217007 | ||
| The CUL3-SPOP-DAXX axis is a novel regulator of VEGFR2 expression in vascular endothelial cells | Q42320699 | ||
| Cytoplasmic E3 ubiquitin ligase CUL9 controls cell proliferation, senescence, apoptosis and genome integrity through p53. | Q43400614 | ||
| Knockdown of CUL4A inhibits invasion and induces apoptosis in osteosarcoma cells | Q43742227 | ||
| Mutational analysis of hypoxia-related genes HIF1alpha and CUL2 in common human cancers | Q43859803 | ||
| FBXW7/hCDC4 is a general tumor suppressor in human cancer. | Q45345209 | ||
| Cullin7: a new gene involved in liver carcinogenesis related to metabolic syndrome | Q46360745 | ||
| CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing | Q47069271 | ||
| Skp2-mediated degradation of p27 regulates progression into mitosis | Q47640200 | ||
| The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1 | Q24315928 | ||
| The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation | Q24315972 | ||
| WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase | Q24316117 | ||
| A Cullin3-KLHL20 Ubiquitin Ligase-Dependent Pathway Targets PML to Potentiate HIF-1 Signaling and Prostate Cancer Progression | Q24322269 | ||
| The hypoxia-controlled FBXL14 ubiquitin ligase targets SNAIL1 for proteasome degradation | Q24324551 | ||
| M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP | Q24329203 | ||
| CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex | Q24336508 | ||
| FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade | Q24338848 | ||
| The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast | Q24532802 | ||
| von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination | Q24554216 | ||
| The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins | Q24564802 | ||
| The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells | Q24599645 | ||
| Cyclin G2 is degraded through the ubiquitin-proteasome pathway and mediates the antiproliferative effect of activin receptor-like kinase 7 | Q24646831 | ||
| Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer | Q24648025 | ||
| Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase | Q24651172 | ||
| Sequence and structural analysis of BTB domain proteins | Q24812693 | ||
| Cullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic Implications | Q26747274 | ||
| The role of cullin 5-containing ubiquitin ligases | Q26749274 | ||
| Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases | Q27657740 | ||
| Molecular Architecture of the Ankyrin SOCS Box Family of Cul5-Dependent E3 Ubiquitin Ligases | Q27678830 | ||
| Structural basis of lenalidomide-induced CK1α degradation by the CRL4(CRBN) ubiquitin ligase | Q27704179 | ||
| The F-box protein Dia2 regulates DNA replication | Q27938990 | ||
| A Yeast GSK-3 Kinase Mck1 Promotes Cdc6 Degradation to Inhibit DNA Re-Replication | Q27939055 | ||
| Histone demethylation by a family of JmjC domain-containing proteins | Q27939224 | ||
| Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA | Q27939872 | ||
| Regulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome Stability | Q28068574 | ||
| Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases | Q28139317 | ||
| Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo | Q28177348 | ||
| Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage | Q28182301 | ||
| The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation | Q28184480 | ||
| Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase | Q28202311 | ||
| T47D breast cancer cell growth is inhibited by expression of VACM-1, a cul-5 gene | Q28265603 | ||
| S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth | Q28269583 | ||
| VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation | Q28272241 | ||
| CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation | Q28290857 | ||
| A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase | Q28295980 | ||
| Hypoxia in cancer: significance and impact on clinical outcome | Q28298305 | ||
| SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation | Q28302907 | ||
| betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis | Q28306984 | ||
| F-box protein FBXL2 targets cyclin D2 for ubiquitination and degradation to inhibit leukemic cell proliferation | Q28383185 | ||
| Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis | Q28388125 | ||
| FBXL2 is a ubiquitin E3 ligase subunit that triggers mitotic arrest | Q28396015 | ||
| F-box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest | Q28396057 | ||
| Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication | Q28507216 | ||
| Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis | Q28508088 | ||
| Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression | Q28509189 | ||
| RNA polymerase II transcription factor SIII. I. Identification, purification, and properties | Q28564363 | ||
| Mouse Fem1b interacts with and induces ubiquitin-mediated degradation of Ankrd37 | Q28594291 | ||
| Circadian Rhythm Disruption in Cancer Biology | Q28972554 | ||
| Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression | Q29615644 | ||
| Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein | Q29615928 | ||
| An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer | Q29616732 | ||
| Diverse somatic mutation patterns and pathway alterations in human cancers | Q29619825 | ||
| Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma | Q30276526 | ||
| Regulation of TGF-β signaling, exit from the cell cycle, and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2. | Q30411902 | ||
| CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation | Q30430339 | ||
| Tethering of SCF(Dia2) to the Replisome Promotes Efficient Ubiquitylation and Disassembly of the CMG Helicase. | Q30663149 | ||
| Expression of the F-box protein SKP2 induces hyperplasia, dysplasia, and low-grade carcinoma in the mouse prostate | Q33186593 | ||
| A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation | Q33268297 | ||
| Phase I Study of the Novel Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (MLN4924) in Patients with Relapsed/Refractory Multiple Myeloma or Lymphoma | Q33427510 | ||
| Ataxin-3 promotes genome integrity by stabilizing Chk1. | Q33635896 | ||
| Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B. | Q33725449 | ||
| The CRL2LRR-1 ubiquitin ligase regulates cell cycle progression during C. elegans development | Q33729305 | ||
| DNA copy number losses in human neoplasms | Q33733232 | ||
| Beta-TrCP recognizes a previously undescribed nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases | Q33756957 | ||
| The role of cullin4B in human cancers | Q33802187 | ||
| Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradation | Q33982295 | ||
| Silymarin Targets β-Catenin Signaling in Blocking Migration/Invasion of Human Melanoma Cells | Q33988164 | ||
| The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation | Q34026690 | ||
| MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5. | Q34031832 | ||
| Downregulation of miR-7 upregulates Cullin 5 (CUL5) to facilitate G1/S transition in human hepatocellular carcinoma cells | Q34039349 | ||
| Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation | Q34043797 | ||
| Thymine DNA glycosylase is a CRL4Cdt2 substrate | Q34044719 | ||
| Regulation of Inducible Nitric-oxide Synthase by the SPRY Domain- and SOCS Box-containing Proteins | Q34157281 | ||
| F-box protein 10, an NF-κB-dependent anti-apoptotic protein, regulates TRAIL-induced apoptosis through modulating c-Fos/c-FLIP pathway | Q34160097 | ||
| The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy | Q34202686 | ||
| Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1. | Q34250835 | ||
| KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs | Q34322749 | ||
| Pevonedistat (MLN4924), a First-in-Class NEDD8-activating enzyme inhibitor, in patients with acute myeloid leukaemia and myelodysplastic syndromes: a phase 1 study | Q34465347 | ||
| The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites | Q34479820 | ||
| Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS. | Q34483086 | ||
| Phase I Study of the Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (TAK-924/MLN4924) in Patients with Advanced Solid Tumors | Q34496360 | ||
| A phase I study of the investigational NEDD8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924) in patients with metastatic melanoma | Q34521260 | ||
| L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes | Q34550320 | ||
| L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage | Q34550325 | ||
| Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins | Q34610662 | ||
| CRL2LRR-1 Targets a CDK Inhibitor for Cell Cycle Control in C. elegans and Actin-Based Motility Regulation in Human Cells | Q34645536 | ||
| Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase | Q34650624 | ||
| CUL7 is a novel antiapoptotic oncogene | Q34702306 | ||
| JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes | Q34712349 | ||
| Structural assembly of cullin-RING ubiquitin ligase complexes | Q34762436 | ||
| Lenalidomide induces degradation of IKZF1 and IKZF3. | Q34934048 | ||
| Cytoplasmic CUL9/PARC Ubiquitin Ligase Is a Tumor Suppressor and Promotes p53-Dependent Apoptosis | Q34942236 | ||
| FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation | Q34981648 | ||
| The neddylation-cullin 2-RBX1 E3 ligase axis targets tumor suppressor RhoB for degradation in liver cancer. | Q35148345 | ||
| Role of β-TrCP ubiquitin ligase receptor in UVB mediated responses in skin | Q35149273 | ||
| Structural regulation of cullin-RING ubiquitin ligase complexes | Q35151712 | ||
| Destruction of full-length androgen receptor by wild-type SPOP, but not prostate-cancer-associated mutants | Q35181646 | ||
| COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases | Q35541468 | ||
| Von Hippel-Lindau tumor suppressor protein and hypoxia-inducible factor in kidney cancer | Q35599988 | ||
| Regulation of Cellular Levels of Sprouty2 Protein by Prolyl Hydroxylase Domain and von Hippel-Lindau Proteins | Q35604936 | ||
| SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protection | Q35613215 | ||
| Radiosensitization of Human Pancreatic Cancer Cells by MLN4924, an Investigational NEDD8-Activating Enzyme Inhibitor | Q35653286 | ||
| Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2. | Q35661995 | ||
| Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family. | Q35740993 | ||
| Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization | Q35857019 | ||
| Cdt1 degradation to prevent DNA re-replication: conserved and non-conserved pathways | Q35878420 | ||
| The Replisome-Coupled E3 Ubiquitin Ligase Rtt101Mms22 Counteracts Mrc1 Function to Tolerate Genotoxic Stress | Q35916165 | ||
| Aberrant expression of microRNAs in gastric cancer and biological significance of miR-574-3p | Q36074982 | ||
| SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/NF-kappaB. | Q36119281 | ||
| Epidermal Growth Factor Receptor Protects Proliferating Cell Nuclear Antigen from Cullin 4A Protein-mediated Proteolysis | Q36137502 | ||
| CRL4-DDB1-VPRBP ubiquitin ligase mediates the stress triggered proteolysis of Mcm10. | Q36180198 | ||
| The role of Cullin3-mediated ubiquitination of the catalytic subunit of PP2A in TRAIL signaling | Q36180733 | ||
| HIF-1α pathway: role, regulation and intervention for cancer therapy | Q36238647 | ||
| FBXW12, a novel F box protein-encoding gene, is deleted or methylated in some cases of epithelial ovarian cancer | Q36261318 | ||
| Tumor suppressor SPOP mediates the proteasomal degradation of progesterone receptors (PRs) in breast cancer cells | Q36309431 | ||
| Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21 CIP1/WAF1 and cyclin D proteins | Q36310068 | ||
| RhoB in cancer suppression | Q36331551 | ||
| SCF(β-TRCP) promotes cell growth by targeting PR-Set7/Set8 for degradation | Q36379597 | ||
| Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes | Q36447819 | ||
| Understanding cullin-RING E3 biology through proteomics-based substrate identification | Q36455676 | ||
| SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication | Q36536516 | ||
| Cullin-5, a ubiquitin ligase scaffold protein, is significantly underexpressed in endometrial adenocarcinomas and is a target of miR-182. | Q36641178 | ||
| SCF(Fbxw15) mediates histone acetyltransferase binding to origin recognition complex (HBO1) ubiquitin-proteasomal degradation to regulate cell proliferation | Q36647292 | ||
| CUL4B promotes replication licensing by up-regulating the CDK2-CDC6 cascade. | Q36695607 | ||
| Skp2 Deficiency Inhibits Chemical Skin Tumorigenesis Independent of p27Kip1 Accumulation | Q36817623 | ||
| Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease | Q36843762 | ||
| Structural insights into early events in the conjugation of ubiquitin and ubiquitin-like proteins | Q36887653 | ||
| A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells | Q36897684 | ||
| The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing | Q36898085 | ||
| Cullin 4A (CUL4A), a direct target of miR-9 and miR-137, promotes gastric cancer proliferation and invasion by regulating the Hippo signaling pathway | Q36962867 | ||
| A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells. | Q36986409 | ||
| The cullin7 E3 ubiquitin ligase: a novel player in growth control | Q37300974 | ||
| Mechanisms and function of substrate recruitment by F-box proteins. | Q37307464 | ||
| CUL2 overexpression driven by CUL2/E2F1/miR-424 regulatory loop promotes HPV16 E7 induced cervical carcinogenesis | Q37327810 | ||
| Radiosensitization by the investigational NEDD8-activating enzyme inhibitor MLN4924 (pevonedistat) in hormone-resistant prostate cancer cells | Q37437499 | ||
| Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I | Q37527678 | ||
| Cullin 7 mediates proteasomal and lysosomal degradations of rat Eag1 potassium channels | Q37591207 | ||
| CUL4A ubiquitin ligase: a promising drug target for cancer and other human diseases | Q37609233 | ||
| The cullin protein family | Q37873586 | ||
| Role of the ubiquitin ligase Fbw7 in cancer progression | Q37962378 | ||
| Insights in cullin 3/WNK4 and its relationship to blood pressure regulation and electrolyte homeostasis | Q38187214 | ||
| Role of Fbxw7 in the maintenance of normal stem cells and cancer-initiating cells | Q38213913 | ||
| Endocrine manifestations of von Hippel-Lindau disease. | Q38328199 | ||
| The SCF/Slimb ubiquitin ligase limits centrosome amplification through degradation of SAK/PLK4. | Q38358118 | ||
| MLN4924 therapy as a novel approach in cancer treatment modalities | Q38570362 | ||
| The SCF-type E3 Ubiquitin Ligases as Cancer Targets | Q38631150 | ||
| Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex | Q38673650 | ||
| Dysregulation of CUL4A and CUL4B Ubiquitin Ligases in Lung Cancer | Q38726208 | ||
| CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis | Q38736268 | ||
| Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate | Q38746625 | ||
| Human DNA Ligase I Interacts with and Is Targeted for Degradation by the DCAF7 Specificity Factor of the Cul4-DDB1 Ubiquitin Ligase Complex | Q38749225 | ||
| Cutting Edge: A Cullin-5-TRAF6 Interaction Promotes TRAF6 Polyubiquitination and Lipopolysaccharide Signaling. | Q38768063 | ||
| Recent advances in SCF ubiquitin ligase complex: Clinical implications | Q38828721 | ||
| Inactivation of the p53-KLF4-CEBPA Axis in Acute Myeloid Leukemia | Q38832347 | ||
| VprBP/DCAF1 Regulates the Degradation and Nonproteolytic Activation of the Cell Cycle Transcription Factor FoxM1. | Q38833602 | ||
| DDB2 is involved in ubiquitination and degradation of PAQR3 and regulates tumorigenesis of gastric cancer cells | Q38849913 | ||
| SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor. | Q38868773 | ||
| FBXL5 modulates HIF-1α transcriptional activity by degradation of CITED2. | Q38877452 | ||
| FBXL5 inhibits metastasis of gastric cancer through suppressing Snail1. | Q38891885 | ||
| Cullin7 is required for lung cancer cell proliferation and is overexpressed in lung cancer | Q38906932 | ||
| KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination | Q38916626 | ||
| MMSET is dynamically regulated during cell-cycle progression and promotes normal DNA replication | Q38920368 | ||
| JMJD2A attenuation affects cell cycle and tumourigenic inflammatory gene regulation in lipopolysaccharide stimulated neuroectodermal stem cells | Q38959420 | ||
| Overexpressed ubiquitin ligase Cullin7 in breast cancer promotes cell proliferation and invasion via down-regulating p53. | Q38977220 | ||
| FBXL5 targets cortactin for ubiquitination-mediated destruction to regulate gastric cancer cell migration | Q38991027 | ||
| Order from clutter: selective interactions at mammalian replication origins | Q39014876 | ||
| Mechanisms and regulation of DNA replication initiation in eukaryotes | Q39017132 | ||
| PIP-box-mediated degradation prohibits re-accumulation of Cdc6 during S phase. | Q39033718 | ||
| CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing | Q39051578 | ||
| Guard the guardian: A CRL4 ligase stands watch over histone production | Q39078077 | ||
| Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation | Q39197334 | ||
| DNA Damage Regulates UHRF1 Stability via the SCFβ-TrCP E3 Ligase | Q39214600 | ||
| The role of PR-Set7 in replication licensing depends on Suv4-20h | Q39244779 | ||
| Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7. | Q39582682 | ||
| Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks | Q39621855 | ||
| Fbxw8 is involved in the proliferation of human choriocarcinoma JEG-3 cells | Q39650269 | ||
| The Neddylation Inhibitor Pevonedistat (MLN4924) Suppresses and Radiosensitizes Head and Neck Squamous Carcinoma Cells and Tumors | Q40071281 | ||
| Estrogen-dependent growth and estrogen receptor (ER)-alpha concentration in T47D breast cancer cells are inhibited by VACM-1, a cul 5 gene | Q40190998 | ||
| Constitutive and UV-induced fibronectin degradation is a ubiquitination-dependent process controlled by beta-TrCP. | Q40270894 | ||
| MLN4924 and 2DG combined treatment enhances the efficiency of radiotherapy in breast cancer cells. | Q40293672 | ||
| Cullin 3 promotes proteasomal degradation of the topoisomerase I-DNA covalent complex | Q40590736 | ||
| Aberrant Expression of CUL4A Is Associated with IL-6/ STAT3 Activation in Colorectal Cancer Progression | Q40612736 | ||
| SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells | Q40651909 | ||
| Inhibition of Liver Carcinoma Cell Invasion and Metastasis by Knockdown of Cullin7 In Vitro and In Vivo | Q40725272 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P304 | page(s) | 19 | |
| P577 | publication date | 2018-03-13 | |
| P1433 | published in | Frontiers in molecular biosciences | Q27726420 |
| P1476 | title | Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy. | |
| P478 | volume | 5 |
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