| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1005220717 |
| P356 | DOI | 10.1038/ONC.2008.44 |
| P698 | PubMed publication ID | 18332868 |
| P5875 | ResearchGate publication ID | 245622892 |
| P2093 | author name string | J Chen | |
| J Huang | |||
| P2860 | cites work | HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase | Q24297940 |
| Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase | Q24298753 | ||
| A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1 | Q24301361 | ||
| Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery | Q24302241 | ||
| CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation | Q24306802 | ||
| Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2 | Q24313491 | ||
| DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest | Q24671784 | ||
| Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle | Q24680705 | ||
| Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization | Q28246519 | ||
| Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors | Q28510087 | ||
| Merlin, the Product of the Nf2 Tumor Suppressor Gene, Is an Inhibitor of the p21-Activated Kinase, Pak1 | Q28513718 | ||
| Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane | Q30443407 | ||
| HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase | Q33290831 | ||
| Cytoplasmic retention of HIV-1 regulatory protein Vpr by protein-protein interaction with a novel human cytoplasmic protein VprBP. | Q33935714 | ||
| ERM-Merlin and EBP50 protein families in plasma membrane organization and function | Q34059680 | ||
| DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase | Q34641190 | ||
| The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor | Q34647751 | ||
| DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases | Q35106169 | ||
| Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy | Q35651812 | ||
| Merlin facilitates ubiquitination and degradation of transactivation-responsive RNA-binding protein. | Q38512574 | ||
| Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac. | Q40181731 | ||
| Molecular insights into neurofibromatosis 2. | Q41489429 | ||
| A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor. | Q42609349 | ||
| The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling. | Q42823880 | ||
| Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli | Q42830999 | ||
| The biphenyl/polychlorinated biphenyl-degradation locus (bph) of Pseudomonas sp. LB400 encodes four additional metabolic enzymes | Q48081618 | ||
| Interdomain interaction of merlin isoforms and its influence on intermolecular binding to NHE-RF | Q73195911 | ||
| Evidence for a cytoskeleton attachment domain at the N-terminus of the NF2 protein | Q73271606 | ||
| Merlin differentially associates with the microtubule and actin cytoskeleton | Q74257128 | ||
| P433 | issue | 29 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 4056-64 | |
| P577 | publication date | 2008-07-03 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation | |
| P478 | volume | 27 |
| Q39282242 | Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP. |
| Q36180198 | CRL4-DDB1-VPRBP ubiquitin ligase mediates the stress triggered proteolysis of Mcm10. |
| Q28389945 | CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth |
| Q37440298 | CRL4s: the CUL4-RING E3 ubiquitin ligases |
| Q54942210 | Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy. |
| Q35208467 | Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype. |
| Q64893783 | Cul4A Modulates Invasion and Metastasis of Lung Cancer Through Regulation of ANXA10. |
| Q36506967 | DCAF1 controls T-cell function via p53-dependent and -independent mechanisms |
| Q37418404 | DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress |
| Q35099829 | Defining the interactions and role of DCAF1/VPRBP in the DDB1-cullin4A E3 ubiquitin ligase complex engaged by HIV-1 Vpr to induce a G2 cell cycle arrest |
| Q36666256 | Dyrk2-associated EDD-DDB1-VprBP E3 ligase inhibits telomerase by TERT degradation |
| Q39609180 | HIV-1 Vpr induces the K48-linked polyubiquitination and proteasomal degradation of target cellular proteins to activate ATR and promote G2 arrest |
| Q36890536 | HIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complex |
| Q38051813 | Lentivirus Vpr and Vpx accessory proteins usurp the cullin4-DDB1 (DCAF1) E3 ubiquitin ligase |
| Q24300692 | Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus |
| Q30474083 | Missense mutations in the NF2 gene result in the quantitative loss of merlin protein and minimally affect protein intrinsic function |
| Q42608826 | Multistep phosphorylation by oncogenic kinases enhances the degradation of the NF2 tumor suppressor merlin |
| Q26825296 | Neurofibromatosis type 2 protein, NF2: an uncoventional cell cycle regulator |
| Q24312855 | PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex |
| Q35971298 | Pathogenic Role of the CRL4 Ubiquitin Ligase in Human Disease |
| Q35665751 | Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response |
| Q38326912 | Purification of the COP9 signalosome complex and binding partners from human T cells |
| Q37320488 | RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival |
| Q37766007 | Roles of Vpr and Vpx in modulating the virus-host cell relationship |
| Q35880315 | SCF E3 ubiquitin ligases as anticancer targets |
| Q57066266 | Synergistic effect of Nutlin-3 combined with MG-132 on schwannoma cells through restoration of merlin and p53 tumour suppressors |
| Q41844088 | Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex |
| Q42782447 | Targeting protein ubiquitylation: DDB1 takes its RING off |
| Q21134793 | The HIV1 protein Vpr acts to enhance constitutive DCAF1-dependent UNG2 turnover |
| Q33891972 | The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase |
| Q24318267 | The human immunodeficiency virus type 2 Vpx protein usurps the CUL4A-DDB1 DCAF1 ubiquitin ligase to overcome a postentry block in macrophage infection |
| Q26783814 | The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implications |
| Q34682328 | Transcriptional and post-translational regulation of the quiescence factor and putative tumor suppressor p150(Sal2). |
| Q28674964 | Ubiquitin E3 ligase CRL4(CDT2/DCAF2) as a potential chemotherapeutic target for ovarian surface epithelial cancer |
| Q24594980 | Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail |
| Q34986007 | VprBP (DCAF1): a promiscuous substrate recognition subunit that incorporates into both RING-family CRL4 and HECT-family EDD/UBR5 E3 ubiquitin ligases |
| Q24299516 | VprBP binds full-length RAG1 and is required for B-cell development and V(D)J recombination fidelity |
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