scholarly article | Q13442814 |
P819 | ADS bibcode | 2017NatCo...815398A |
P6179 | Dimensions Publication ID | 1085460780 |
P356 | DOI | 10.1038/NCOMMS15398 |
P932 | PMC publication ID | 5458144 |
P698 | PubMed publication ID | 28530236 |
P50 | author | Katherine A Donovan | Q64355331 |
Eric S. Fischer | Q43073160 | ||
P2093 | author name string | Jian An | |
Michael B Stadler | |||
Jan Seebacher | |||
Ragna Sack | |||
Charles M Ponthier | |||
P2860 | cites work | An Atypical E3 Ligase Zinc Finger Protein 91 Stabilizes and Activates NF-κB-inducing Kinase via Lys63-linked Ubiquitination | Q24294345 |
Identification of a primary target of thalidomide teratogenicity | Q24302178 | ||
Multidimensional proteomics for cell biology | Q27008027 | ||
Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide | Q27684738 | ||
Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs | Q27694755 | ||
Structural basis of lenalidomide-induced CK1α degradation by the CRL4(CRBN) ubiquitin ligase | Q27704179 | ||
Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome | Q27704406 | ||
A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase | Q27713259 | ||
RING domain E3 ubiquitin ligases | Q27860546 | ||
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias | Q27860710 | ||
The ubiquitin system | Q27860803 | ||
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics | Q28131742 | ||
Global quantification of mammalian gene expression control | Q28238103 | ||
The ubiquitin code | Q28265104 | ||
The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins | Q28303081 | ||
Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells | Q28303091 | ||
A novel pulse-chase SILAC strategy measures changes in protein decay and synthesis rates induced by perturbation of proteostasis with an Hsp90 inhibitor | Q28535467 | ||
DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation | Q28830958 | ||
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification | Q29547200 | ||
Proteomics. Tissue-based map of the human proteome | Q29617248 | ||
limma powers differential expression analyses for RNA-sequencing and microarray studies | Q29617988 | ||
Analysis of intronic and exonic reads in RNA-seq data characterizes transcriptional and post-transcriptional regulation. | Q30975976 | ||
Quantitative temporal viromics: an approach to investigate host-pathogen interaction | Q33722378 | ||
Antitumor activity of thalidomide in refractory multiple myeloma | Q33880642 | ||
Options and considerations when selecting a quantitative proteomics strategy | Q34125509 | ||
Tandem Mass Tags: A Novel Quantification Strategy for Comparative Analysis of Complex Protein Mixtures by MS/MS | Q34192662 | ||
MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes. | Q34434094 | ||
Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4. | Q34479551 | ||
HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins | Q34480529 | ||
Catalytic in vivo protein knockdown by small-molecule PROTACs. | Q34480735 | ||
Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS. | Q34483086 | ||
Cancerous inhibitor of PP2A is targeted by natural compound celastrol for degradation in non-small-cell lung cancer. | Q35055737 | ||
Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.). | Q35064910 | ||
Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging | Q35666096 | ||
A quantitative spatial proteomics analysis of proteome turnover in human cells | Q35863277 | ||
Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation | Q36044823 | ||
Understanding cullin-RING E3 biology through proteomics-based substrate identification | Q36455676 | ||
Neutron-encoded mass signatures for multiplexed proteome quantification | Q36728847 | ||
Ubiquitin proteasome system (UPS): what can chromatin do for you? | Q36741709 | ||
The thalidomide saga | Q36763353 | ||
Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon | Q36956452 | ||
Identification of long-lived proteins reveals exceptional stability of essential cellular structures | Q37210826 | ||
Lenalidomide: deciphering mechanisms of action in myeloma, myelodysplastic syndrome and beyond | Q38619028 | ||
Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover. | Q38681448 | ||
Ubiquitin ligase trapping identifies an SCF(Saf1) pathway targeting unprocessed vacuolar/lysosomal proteins. | Q39900436 | ||
A set of baculovirus transfer vectors for screening of affinity tags and parallel expression strategies | Q39908030 | ||
Hyperplexing: a method for higher-order multiplexed quantitative proteomics provides a map of the dynamic response to rapamycin in yeast | Q42131449 | ||
Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity | Q42696060 | ||
QuasR: quantification and annotation of short reads in R. | Q43213442 | ||
The evolution of thalidomide and its IMiD derivatives as anticancer agents | Q44824886 | ||
Zinc-finger protein 91 plays a key role in LIGHT-induced activation of non-canonical NF-κB pathway. | Q45924445 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | limma | Q112236343 |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 15398 | |
P577 | publication date | 2017-05-22 | |
P1433 | published in | Nature Communications | Q573880 |
P1476 | title | pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4CRBN ubiquitin ligase | |
P478 | volume | 8 |
Q89320710 | CK1α and IRF4 are essential and independent effectors of immunomodulatory drugs in primary effusion lymphoma |
Q52585230 | Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK). |
Q54942210 | Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy. |
Q91596094 | Crystal structure of the SALL4-pomalidomide-cereblon-DDB1 complex |
Q58618295 | Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN |
Q64940546 | Delineating the role of cooperativity in the design of potent PROTACs for BTK. |
Q90135125 | Development of targeted protein degradation therapeutics |
Q92229206 | Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera |
Q92358733 | Extensive transcriptional responses are co-ordinated by microRNAs as revealed by Exon-Intron Split Analysis (EISA) |
Q47411643 | Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead. |
Q93138758 | Monitoring tumour burden and therapeutic response through analysis of circulating tumour DNA and extracellular RNA in multiple myeloma patients |
Q92647353 | Novel immunomodulatory drugs and neo-substrates |
Q89070297 | Plasticity in binding confers selectivity in ligand-induced protein degradation |
Q91559627 | RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation |
Q91322597 | SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate |
Q92352921 | Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations |
Q56866834 | Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome |
Q90634062 | The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L |
Q57024673 | is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice |
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