The role of cullin 5-containing ubiquitin ligases

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The role of cullin 5-containing ubiquitin ligases is …
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P6179Dimensions Publication ID1032657479
P356DOI10.1186/S13008-016-0016-3
P3181OpenCitations bibliographic resource ID4618562
P932PMC publication ID4812663
P698PubMed publication ID27030794
P5875ResearchGate publication ID299539258

P2093author name stringTakumi Kamura
Fumihiko Okumura
Akiko Joo-Okumura
Kunio Nakatsukasa
P2860cites workHuman immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control.Q39874039
The complete DNA sequence and genomic organization of the avian adenovirus CELO.Q39874304
Identification of a novel antiapoptotic protein, GAM-1, encoded by the CELO adenovirusQ39879136
Restriction of Src activity by Cullin-5Q39894835
Granulocytic differentiation of HL-60 promyelocytic leukemia cells is associated with increased expression of Cul5.Q39899501
Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1.Q39911661
Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligasesQ40026609
Pathways of activation of the Epstein-Barr virus productive cycleQ40062871
Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradationQ40140948
The adenovirus E4orf6 E3 ubiquitin ligase complex assembles in a novel fashionQ40157700
Estrogen-dependent growth and estrogen receptor (ER)-alpha concentration in T47D breast cancer cells are inhibited by VACM-1, a cul 5 geneQ40190998
Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 proteinQ40302630
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradationQ40328896
The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residuesQ40337569
Ubiquitination of APOBEC3 proteins by the Vif-Cullin5-ElonginB-ElonginC complex.Q40348544
Id2 mediates tumor initiation, proliferation, and angiogenesis in Rb mutant mice.Q40435177
Phosphorylation by the DHIPK2 protein kinase modulates the corepressor activity of GrouchoQ40440527
Selective assembly of HIV-1 Vif-Cul5-ElonginB-ElonginC E3 ubiquitin ligase complex through a novel SOCS box and upstream cysteinesQ40485825
Phosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradationQ40485830
Production of infectious SIVagm from human cells requires functional inactivation but not viral exclusion of human APOBEC3G.Q40495589
Inhibition of hepatitis B virus replication by APOBEC3G.Q40576734
SOCS1 [corrected] inhibits HPV-E7-mediated transformation by inducing degradation of E7 proteinQ40578400
Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complexQ40717443
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.Q40816941
Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.Q40889649
APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptaseQ40899809
Cloning, tissue expression, and chromosomal location of the mouse insulin receptor substrate 4 geneQ40968948
HIV-1 Vpr increases viral expression by manipulation of the cell cycle: A mechanism for selection of Vpr in vivoQ41071784
asb11 is a regulator of embryonic and adult regenerative myogenesis.Q41254732
AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamicsQ41603230
Id-2 regulates critical aspects of human cytotrophoblast differentiation, invasion and migrationQ41713579
SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agentsQ22009063
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognitionQ24297748
ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexesQ24297841
Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formationQ24300183
T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restrictionQ24300389
Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expressionQ24300917
Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1Q24304257
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNAQ24305266
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survivalQ24311448
A family of cytokine-inducible inhibitors of signallingQ24313168
A new protein containing an SH2 domain that inhibits JAK kinasesQ24313242
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugationQ24314520
The E3 ubiquitin-protein ligase Triad1 inhibits clonogenic growth of primary myeloid progenitor cellsQ24317495
Twenty proteins containing a C-terminal SOCS box form five structural classesQ24317684
ASB4 is a hydroxylation substrate of FIH and promotes vascular differentiation via an oxygen-dependent mechanismQ24320200
Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23Q24320339
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligasesQ24322407
Ankyrin repeat and suppressors of cytokine signaling box protein asb-9 targets creatine kinase B for degradationQ24322983
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene familyQ24336422
Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cellsQ24336533
TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexesQ24337489
Ankyrin repeat and SOCS box 3 (ASB3) mediates ubiquitination and degradation of tumor necrosis factor receptor IIQ24529081
Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machineryQ24538586
Cullin 5 destabilizes Cas to inhibit Src-dependent cell transformationQ30577461
Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP.Q31014772
Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivoQ31046841
Asb6, an adipocyte-specific ankyrin and SOCS box protein, interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complexQ31087151
Homeodomain-interacting protein kinase-2 regulates apoptosis in developing sensory and sympathetic neuronsQ31117827
EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressorsQ33261811
Polymorphisms of CUL5 are associated with CD4+ T cell loss in HIV-1 infected individualsQ33270513
Degradation of phosphorylated p53 by viral protein-ECS E3 ligase complexQ33489621
E3 ubiquitin ligase Cullin-5 modulates multiple molecular and cellular responses to heat shock protein 90 inhibition in human cancer cellsQ33606911
Phosphorylation of VACM-1/Cul5 by protein kinase A regulates its neddylation and antiproliferative effectQ33717656
Essential role for the d-Asb11 cul5 Box domain for proper notch signaling and neural cell fate decisions in vivoQ33761287
A functional complex of adenovirus proteins E1B-55kDa and E4orf6 is necessary to modulate the expression level of p53 but not its transcriptional activity.Q33827516
SWiP-1: novel SOCS box containing WD-protein regulated by signalling centres and by Shh during developmentQ33863869
Homeodomain-interacting protein kinase-2 mediates CtBP phosphorylation and degradation in UV-triggered apoptosisQ33864038
Both Epstein-Barr virus (EBV)-encoded trans-acting factors, EB1 and EB2, are required to activate transcription from an EBV early promoterQ33880983
Role of C-peptide in human physiologyQ33898773
Regulation of Apobec3F and human immunodeficiency virus type 1 Vif by Vif-Cul5-ElonB/C E3 ubiquitin ligaseQ33908716
The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradationQ34026690
MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5.Q34031832
VACM-1/cul5 expression in vascular tissue in vivo is induced by water deprivation and its expression in vitro regulates aquaporin-1 concentrationsQ34031947
Ankyrin repeat and SOCS box containing protein 4 (Asb-4) colocalizes with insulin receptor substrate 4 (IRS4) in the hypothalamic neurons and mediates IRS4 degradationQ34033979
Aquaporin-2 Levelsin vitroandin vivoare Regulated by VACM-1, a Cul 5 GeneQ34034478
Downregulation of miR-7 upregulates Cullin 5 (CUL5) to facilitate G1/S transition in human hepatocellular carcinoma cellsQ34039349
ASB-2 inhibits growth and promotes commitment in myeloid leukemia cellsQ34099506
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.Q34108288
The von Hippel-Lindau tumor suppressor proteinQ34132816
Suppressor of cytokine signaling 1 (SOCS1) limits NFkappaB signaling by decreasing p65 stability within the cell nucleusQ34150376
Regulation of Inducible Nitric-oxide Synthase by the SPRY Domain- and SOCS Box-containing ProteinsQ34157281
TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity.Q34212836
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infectionQ34242229
EBV replication enzymesQ34302522
Creatine kinase in non-muscle tissues and cellsQ34314994
Oligosaccharyltransferase activity is associated with a protein complex composed of ribophorins I and II and a 48 kd proteinQ34369417
Filamins but not Janus kinases are substrates of the ASB2α cullin-ring E3 ubiquitin ligase in hematopoietic cells.Q34391842
The SPRY domain-containing SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathwayQ34394811
The Vif and Vpr accessory proteins independently cause HIV-1-induced T cell cytopathicity and cell cycle arrestQ34480135
Resveratrol: from grapevines to mammalian biologyQ34543061
Chronic treatment with resveratrol induces redox stress- and ataxia telangiectasia-mutated (ATM)-dependent senescence in p53-positive cancer cells.Q34581035
Requirement of HIV-1 Vif C-terminus for Vif-CBF-β interaction and assembly of CUL5-containing E3 ligaseQ34695564
A missed exit: Reelin sets in motion Dab1 polyubiquitination to put the break on neuronal migrationQ34714076
Functional analysis of Asb-1 using genetic modification in miceQ24550851
Maspin is not required for embryonic development or tumour suppressionQ24612315
Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLKQ24624946
Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogensQ24630289
The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plateQ24669733
Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical developmentQ24672124
Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin BQ24685157
Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activityQ24685633
The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycleQ24685965
Analysis of CUL-5 expression in breast epithelial cells, breast cancer cell lines, normal tissues and tumor tissuesQ24806313
Cellullar insights into cerebral cortical development: focusing on the locomotion mode of neuronal migrationQ26779317
The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: new therapeutic targetsQ26782593
Molecular Architecture of the Ankyrin SOCS Box Family of Cul5-Dependent E3 Ubiquitin LigasesQ27678830
Multimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin LigasesQ27679000
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif proteinQ27860488
Notch signaling: from the outside inQ28139768
Creatine and creatinine metabolismQ28140735
VACM-1, a cullin gene family member, regulates cellular signalingQ28140946
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcriptsQ28179446
DNA deamination mediates innate immunity to retroviral infectionQ28179534
Species-specific exclusion of APOBEC3G from HIV-1 virions by VifQ28187133
Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligaseQ28198223
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2Q28201656
Expression of VACM-1 protein in cultured rat adrenal endothelial cells is linked to the cell cycleQ28202165
Hypermutation of HIV-1 DNA in the Absence of the Vif ProteinQ28204475
HIV-1 Vif Blocks the Antiviral Activity of APOBEC3G by Impairing Both Its Translation and Intracellular StabilityQ28207304
Reelin and brain developmentQ28207865
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2Q28210189
Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF ComplexQ28210666
Role of the reelin signaling pathway in central nervous system developmentQ28214353
Insulin biosynthesis: evidence for a precursorQ28238900
Notch signaling: control of cell communication and cell fateQ28245948
Maspin plays an essential role in early embryonic developmentQ28246940
Aberrant Splicing of a Mouse disabled Homolog, mdab1, in the scrambler MouseQ28248620
mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTORQ28251026
DEPTOR, an mTOR Inhibitor, Is a Physiological Substrate of SCFβTrCP E3 Ubiquitin Ligase and Regulates Survival and AutophagyQ28251037
mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTORQ28251047
Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in miceQ28251984
Neuronal position in the developing brain is regulated by mouse disabled-1Q28251995
Core-binding factors in hematopoiesis and immune functionQ28262826
T47D breast cancer cell growth is inhibited by expression of VACM-1, a cul-5 geneQ28265603
Absence of Fyn and Src causes a reeler-like phenotypeQ28272263
Phosphorylation of Vif and its role in HIV-1 replicationQ28278306
Cortical neuronal migration mutants suggest separate but intersecting pathwaysQ28286948
Mitogen-activated Protein Kinase Phosphorylates and Regulates the HIV-1 Vif ProteinQ28287061
Retroviral restriction by APOBEC proteinsQ28290721
Expression cloning of an AVP-activated, calcium-mobilizing receptor from rabbit kidney medullaQ28293389
A mechanism for inhibiting the SUMO pathwayQ28293640
VACM-1 receptor is specifically expressed in rabbit vascular endothelium and renal collecting tubuleQ28296762
Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3GQ28484619
Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptorsQ28507618
Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survivalQ28509866
MUF1/leucine-rich repeat containing 41 (LRRC41), a substrate of RhoBTB-dependent cullin 3 ubiquitin ligase complexes, is a predominantly nuclear dimeric proteinQ28511797
Osmotic stress increases cullin-5 (cul-5) mRNA in the rat cerebral cortex, hypothalamus and kidneyQ28570521
Expression of VACM-1/cul5 mutant in endothelial cells induces MAPK phosphorylation and maspin degradation and converts cells to the angiogenic phenotypeQ28578323
Cullin-5 is ubiquitous in the rat brainQ28578330
Vasopressin-activated calcium-mobilizing (VACM-1) receptor mRNA is present in peripheral organs and the central nervous system of the laboratory ratQ28584213
Structure and function of a new STAT-induced STAT inhibitorQ28584775
Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2Q28588947
ARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune systemQ28593507
Evidence for selection at HIV host susceptibility genes in a West Central African human populationQ28710092
Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complexQ29041391
Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genomeQ29618742
The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 VifQ29618938
The tuberous sclerosis complexQ29619128
Exploring the diversity of SPRY/B30.2-mediated interactionsQ30009976
ASB9 interacts with ubiquitous mitochondrial creatine kinase and inhibits mitochondrial functionQ30494036
Cullin 5 regulates cortical layering by modulating the speed and duration of Dab1-dependent neuronal migrationQ30494388
Molecular effects of proinsulin C-peptideQ34756498
SOCS-1 mediates ubiquitylation and degradation of GM-CSF receptorQ35006328
The ubiquitin ligase ASB4 promotes trophoblast differentiation through the degradation of ID2Q35107355
Mechanism of control of Na,K-ATPase in principal cells of the mammalian collecting ductQ35134782
How the ankyrin and SOCS box protein, ASB9, binds to creatine kinaseQ35143308
Functional and structural insights into ASB2alpha, a novel regulator of integrin-dependent adhesion of hematopoietic cellsQ35182907
Flexible Cullins in Cullin-RING E3 Ligases Allosterically Regulate UbiquitinationQ35562631
Structural Features of Antiviral APOBEC3 Proteins are Linked to Their Functional ActivitiesQ35627352
Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?Q35655105
Human genes that limit AIDS.Q35787248
iNOS (NOS2) at a glanceQ35805205
Patterns of neuronal migration in the embryonic cortexQ35818625
The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection.Q35831790
A Mechanism Underlying NOTCH-Induced and Ubiquitin-mediated JAK3 DegradationQ35842064
HIV-1 Vif promotes the G1- to S-phase cell-cycle transitionQ35874198
Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells.Q35883364
The Vif accessory protein alters the cell cycle of human immunodeficiency virus type 1 infected cellsQ35916117
XRab40 and XCullin5 form a ubiquitin ligase complex essential for the noncanonical Wnt pathwayQ35941534
Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis ComplexQ35952307
The Role of Elongin BC-Containing Ubiquitin LigasesQ35971082
The novel gene asb11: a regulator of the size of the neural progenitor compartmentQ36118426
Substrates of the ASB2α E3 ubiquitin ligase in dendritic cells.Q36249918
WSB1 promotes tumor metastasis by inducing pVHL degradationQ36286769
Notch signalling in vertebrate neural developmentQ36374960
E4Orf6-E1B-55k-dependent degradation of de novo-generated adeno-associated virus type 5 Rep52 and capsid proteins employs a cullin 5-containing E3 ligase complexQ36498213
Specific binding of proinsulin C-peptide to human cell membranesQ36671827
APOBEC3G is degraded by the proteasomal pathway in a Vif-dependent manner without being polyubiquitylatedQ36726563
Polymorphic proteins encoded within BZLF1 of defective and standard Epstein-Barr viruses disrupt latencyQ36919739
ASB2 targets filamins A and B to proteasomal degradationQ37003539
RUNX genes in development and cancer: regulation of viral gene expression and the discovery of RUNX family genesQ37013889
Identification of integrin alpha3 as a new substrate of the adenovirus E4orf6/E1B 55-kilodalton E3 ubiquitin ligase complexQ37191952
E1B 55k-independent dissociation of the DNA ligase IV/XRCC4 complex by E4 34k during adenovirus infectionQ37210181
Host genes associated with HIV/AIDS: advances in gene discoveryQ37220761
Oncogenic potential of the adenovirus E4orf6 proteinQ37247046
Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligaseQ41889239
Both Rbx1 and Rbx2 exhibit a functional role in the HIV-1 Vif-Cullin5 E3 ligase complex in vitroQ42145814
Structural basis for hijacking CBF-β and CUL5 E3 ligase complex by HIV-1 Vif.Q42152378
HIV: Ringside viewsQ42233698
SAG/RBX2 is a novel substrate of NEDD4-1 E3 ubiquitin ligase and mediates NEDD4-1 induced chemosensitizationQ42237216
Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cellsQ42554487
Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexesQ42725282
Geldanamycin-Induced Destabilization of Raf-1 Involves the ProteasomeQ42834381
APOBEC3-mediated editing in HIV type 1 from pediatric patients and its association with APOBEC3G/CUL5 polymorphisms and Vif variabilityQ43591014
The HIV-1 Vif protein mediates degradation of Vpr and reduces Vpr-induced cell cycle arrest.Q43948762
Arginine vasopressin modulates expression of neuronal NOS in rat renal medullaQ44094441
Flavonoid effects relevant to cancerQ44209255
Alterations of cullin-5 mRNA levels in the rat central nervous system following hemorrhagic shockQ44360851
Effect of HIV-1 Vif variability on progression to pediatric AIDS and its association with APOBEC3G and CUL5 polymorphismsQ44423620
PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains.Q44542308
Stimulation of endothelial nitric oxide synthase by proinsulin C-peptideQ44659085
Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virusQ45840879
HIF1 regulates WSB‐1 expression to promote hypoxia‐induced chemoresistance in hepatocellular carcinoma cellsQ46246530
C-peptide increases the expression of vasopressin-activated calcium-mobilizing receptor gene through a G protein-dependent pathwayQ46372090
The ECS(SPSB) E3 ubiquitin ligase is the master regulator of the lifetime of inducible nitric-oxide synthaseQ46979057
Discrete expression of insulin receptor substrate-4 mRNA in adult rat brainQ48090584
Cullin 5 gene expression in the rat cerebral cortex and hippocampus following traumatic brain injury (TBI).Q48409427
Crystal structure of Human ASB9-2 and substrate-recognition of CKB.Q48614807
C. elegans RBX-2-CUL-5- and RBX-1-CUL-2-based complexes are redundant for oogenesis and activation of the MAP kinase MPK-1.Q50641188
Gene expression profile signatures indicate a role for Wnt signaling in endothelial commitment from embryonic stem cellsQ50941267
Crystallization and preliminary X-ray analysis of the splice variant of human ankyrin repeat and suppressor of cytokine signaling box protein 9 (hASB9-2).Q51775007
Von Hippel-Lindau diseaseQ51971299
TLR regulation of SPSB1 controls inducible nitric oxide synthase induction.Q54351717
Clinical significance of ASB9 in human colorectal cancer.Q54409134
Targeting SUMO E1 to Ubiquitin LigasesQ56777120
Secretion of Proinsulin C-Peptide by Pancreatic β Cells and its Circulation in BloodQ59073402
Proinsulin C-peptide increases nitric oxide production by enhancing mitogen-activated protein-kinase-dependent transcription of endothelial nitric oxide synthase in aortic endothelial cells of Wistar ratsQ62748149
Adenovirus E4orf6 assembles with Cullin5-ElonginB-ElonginC E3 ubiquitin ligase through an HIV/SIV Vif-like BC-box to regulate p53Q64377210
Role of protein phosphatase in the regulation of Na+-K+-ATPase by vasopressin in the cortical collecting ductQ71634949
alpha 3A beta 1 integrin localizes to focal contacts in response to diverse extracellular matrix proteinsQ72055369
Expression of the genes encoding the vasopressin-activated calcium-mobilizing receptor and the dual angiotensin II/vasopressin receptor in the rat central nervous systemQ73884149
The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cellsQ74190457
Proinsulin C-peptide and its analogues induce intracellular Ca2+ increases in human renal tubular cellsQ74768800
Kaposi’s sarcoma-associated herpesvirus-encoded LANA positively affects on ubiquitylation of p53Q82344523
Phosphorylation of serine 323 of ASB2α is pivotal for the targeting of filamin A to degradationQ85941974
ASB2α, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domainQ37272236
The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppressionQ37289267
Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activityQ37368468
Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligaseQ37453413
Ligase IV syndromeQ37494850
The MRE11 complex: starting from the ends.Q37526483
Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.Q37574153
Role for Reelin in stabilizing cortical architectureQ37769616
SOCS proteins in regulation of receptor tyrosine kinase signalingQ38202542
How does Reelin control neuronal migration and layer formation in the developing mammalian neocortex?Q38223536
New insights into the mechanism for VACM-1/cul5 expression in vascular tissue in vivoQ38265747
The assembly of Vif ubiquitin E3 ligase for APOBEC3 degradationQ38269459
d-Asb11 is an essential mediator of canonical Delta-Notch signallingQ38287559
Cell regulation by phosphotyrosine-targeted ubiquitin ligasesQ38380126
Kinase inhibition, competitive binding and proteasomal degradation: resolving the molecular function of the suppressor of cytokine signaling (SOCS) proteinsQ38530632
TGF-β superfamily signaling in testis formation and early male germline development.Q38616217
Cytoskeletal signaling in TGFβ-induced epithelial-mesenchymal transitionQ38626767
Downregulation of MicroRNA-145 Caused by Hepatitis B Virus X Protein Promotes Expression of CUL5 and Contributes to Pathogenesis of Hepatitis B Virus-Associated Hepatocellular CarcinomaQ38824000
Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells.Q38831129
Analysis of the Cullin binding sites of the E4orf6 proteins of human adenovirus E3 ubiquitin ligases.Q38854475
SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor.Q38868773
Expression of ankyrin repeat and SOCS box containing 4 (ASB4) confers migration and invasion properties of hepatocellular carcinoma cellsQ38996400
Role of E1B55K in E4orf6/E1B55K E3 Ligase Complexes Formed by Different Human Adenovirus SerotypesQ39174506
Suppressor of cytokine signaling 1 blocks mitosis in human melanoma cells.Q39273551
Mutational analysis of VACM-1/cul5 exons in cancer cell linesQ39531701
WSB-1, a novel IL-21 receptor binding molecule, enhances the maturation of IL-21 receptor.Q39564771
Two distinct activities contribute to the oncogenic potential of the adenovirus type 5 E4orf6 proteinQ39585092
Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K proteinQ39602482
Serotype-specific inactivation of the cellular DNA damage response during adenovirus infectionQ39619768
The E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificityQ39633445
Resveratrol enhances anti-proliferative effect of VACM-1/cul5 in T47D cancer cellsQ39643768
Adeno-associated virus small rep proteins are modified with at least two types of polyubiquitinationQ39778963
Expression of Epstein-Barr virus BZLF1 immediate-early protein induces p53 degradation independent of MDM2, leading to repression of p53-mediated transcription.Q39859670
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
P304page(s)1
P577publication date2016-01-01
P1433published inCell DivisionQ2248491
P1476titleThe role of cullin 5-containing ubiquitin ligases
P478volume11

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