Mutational analysis of VACM-1/cul5 exons in cancer cell lines

scientific article published on July 2011

Mutational analysis of VACM-1/cul5 exons in cancer cell lines is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1600-0463.2011.02747.X
P8608Fatcat IDrelease_m3jahiqgnrgnvebcwirxdt4ski
P698PubMed publication ID21635549

P50authorMaria A Burnatowska-HledinQ96246337
P2093author name stringAngelica N Willis
James Resau
Alyssa E Johnson
Steven P Lewis
P2860cites workRegulation of cullin-RING E3 ubiquitin-ligases by neddylation and dimerization.Q37385841
Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaksQ39621855
Resveratrol enhances anti-proliferative effect of VACM-1/cul5 in T47D cancer cellsQ39643768
No evidence for DNA methylation of von Hippel-Lindau ubiquitin ligase complex genes in breast cancerQ39672338
Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia.Q39732225
Restriction of Src activity by Cullin-5Q39894835
Estrogen-dependent growth and estrogen receptor (ER)-alpha concentration in T47D breast cancer cells are inhibited by VACM-1, a cul 5 geneQ40190998
Mutational analysis of hypoxia-related genes HIF1alpha and CUL2 in common human cancersQ43859803
IFN-alpha2b and thalidomide synergistically inhibit tumor-induced angiogenesisQ44363526
Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans.Q47069590
A novel nonsense mutation in CUL4B gene in three brothers with X-linked mental retardation syndromeQ50270965
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modificationQ24316067
Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23Q24320339
Characterization of NEDD8, a developmentally down-regulated ubiquitin-like proteinQ24322977
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene familyQ24336422
The Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimerQ24685712
Analysis of CUL-5 expression in breast epithelial cells, breast cancer cell lines, normal tissues and tumor tissuesQ24806313
Mutations of the BRAF gene in human cancerQ27860760
Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteinsQ27933764
Covalent modification of all members of human cullin family proteins by NEDD8Q28140243
VACM-1, a cul-5 gene, inhibits cellular growth by a mechanism that involves MAPK and p53 signaling pathwaysQ28201553
Expression of VACM-1 protein in cultured rat adrenal endothelial cells is linked to the cell cycleQ28202165
Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF ComplexQ28210666
Mutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardationQ28286574
Expression of VACM-1/cul5 mutant in endothelial cells induces MAPK phosphorylation and maspin degradation and converts cells to the angiogenic phenotypeQ28578323
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancerQ29616732
NEDD8-targeting drug MLN4924 elicits DNA rereplication by stabilizing Cdt1 in S phase, triggering checkpoint activation, apoptosis, and senescence in cancer cellsQ30429284
Polymorphisms of CUL5 are associated with CD4+ T cell loss in HIV-1 infected individualsQ33270513
Phosphorylation of VACM-1/Cul5 by protein kinase A regulates its neddylation and antiproliferative effectQ33717656
Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell linesQ33843555
Cullins and cancerQ34365216
Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospectsQ34623003
Role of the NEDD8 modification of Cul2 in the sequential activation of ECV complexQ35249854
Role of VHL gene mutation in human cancerQ35990141
Genetic and expression aberrations of E3 ubiquitin ligases in human breast cancerQ36627994
Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugationQ37101488
Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.Q37250634
P433issue7
P921main subjectmutational analysisQ1955810
P304page(s)421-430
P577publication date2011-07-01
P1433published inActa Pathologica et Microbiologica ScandinavicaQ15756643
P1476titleMutational analysis of VACM-1/cul5 exons in cancer cell lines
P478volume119