Multimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin Ligases

scientific article

Multimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin Ligases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/BI400758H
P932PMC publication ID3756526
P698PubMed publication ID23837592
P5875ResearchGate publication ID248382930

P50authorAlessio CiulliQ28321884
Dijana Matak-VinkovićQ90691598
P2093author name stringAlessio Ciulli
Jemima C Thomas
P2860cites workCullin-RING ubiquitin ligases: global regulation and activation cyclesQ21203558
The ubiquitin-proteasome proteolytic pathway: destruction for the sake of constructionQ24292709
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complexQ24294734
ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexesQ24297841
Structural basis of dimerization-dependent ubiquitination by the SCF(Fbx4) ubiquitin ligaseQ24300948
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligasesQ24322407
Ankyrin repeat and suppressors of cytokine signaling box protein asb-9 targets creatine kinase B for degradationQ24322983
Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligaseQ24336527
Regulation of Hypoxia-Inducible mRNAs by the von Hippel-Lindau Tumor Suppressor Protein Requires Binding to Complexes Containing Elongins B/C and Cul2Q24523680
Ankyrin repeat and SOCS box 3 (ASB3) mediates ubiquitination and degradation of tumor necrosis factor receptor IIQ24529081
Specific small molecule inhibitors of Skp2-mediated p27 degradationQ24596988
The ankyrin repeat as molecular architecture for protein recognitionQ24646394
Structural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assemblyQ24658171
Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitinationQ27645983
The SOCS Box Domain of SOCS3: Structure and Interaction with the ElonginBC-Cullin5 Ubiquitin LigaseQ27651007
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin LigasesQ27657740
An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligaseQ27662837
Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin LigasesQ27675990
Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α InteractionQ27677509
RING domain E3 ubiquitin ligasesQ27860546
Mechanisms underlying ubiquitinationQ27860656
The ubiquitin systemQ27860803
F-Box Proteins Are Receptors that Recruit Phosphorylated Substrates to the SCF Ubiquitin-Ligase ComplexQ27934075
Function and regulation of cullin-RING ubiquitin ligasesQ28131707
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancerQ29616732
The ankyrin repeat: a diversity of interactions on a common structural frameworkQ29616794
Protein Structure and the Energetics of Protein Stability.Q30329721
ASB9 interacts with ubiquitous mitochondrial creatine kinase and inhibits mitochondrial functionQ30494036
Biophysical characterization of the free IkappaBalpha ankyrin repeat domain in solution.Q33204174
Ion mobility-mass spectrometry reveals long-lived, unfolded intermediates in the dissociation of protein complexesQ33298819
Autoantibodies as potential biomarkers for breast cancerQ33332063
Ankyrin repeat and SOCS box containing protein 4 (Asb-4) colocalizes with insulin receptor substrate 4 (IRS4) in the hypothalamic neurons and mediates IRS4 degradationQ34033979
Core-Binding Factor β Increases the Affinity between Human Cullin 5 and HIV-1 Vif within an E3 Ligase ComplexQ34034114
ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complexQ34375157
Gas-phase folding and unfolding of cytochrome c cations.Q34468414
Evidence for macromolecular protein rings in the absence of bulk water.Q34468487
Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligaseQ34650624
Structural assembly of cullin-RING ubiquitin ligase complexesQ34762436
Structural regulation of cullin-RING ubiquitin ligase complexesQ35151712
The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat familiesQ35211894
Flexible Cullins in Cullin-RING E3 Ligases Allosterically Regulate UbiquitinationQ35562631
Heat capacity in proteinsQ36083067
The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppressionQ37289267
Native mass spectrometry: a bridge between interactomics and structural biologyQ37313905
CRL4s: the CUL4-RING E3 ubiquitin ligasesQ37440298
The cullin protein familyQ37873586
Use of ion mobility mass spectrometry and a collision cross-section algorithm to study an organometallic ruthenium anticancer complex and its adducts with a DNA oligonucleotideQ38349496
Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligasesQ40026609
Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells--evidence for cullin dimerizationQ40178983
BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.Q40633677
Structural characterization of the tumor suppressor p16, an ankyrin-like repeat proteinQ42845500
Studies of the Ankyrin Repeats of the Drosophila melanogaster Notch Receptor. 2. Solution Stability and Cooperativity of UnfoldingQ43809916
Crystal structure of Human ASB9-2 and substrate-recognition of CKB.Q48614807
Clinical significance of ASB9 in human colorectal cancer.Q54409134
Determining the stoichiometry and interactions of macromolecular assemblies from mass spectrometryQ80093527
P433issue31
P407language of work or nameEnglishQ1860
P921main subjectprotein structureQ735188
P304page(s)5236-46
P577publication date2013-08-06
P1433published inBiochemistryQ764876
P1476titleMultimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin Ligases
P478volume52

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cites work (P2860)
Q57283088A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability
Q35080292Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).
Q38673650Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex
Q34785767Cullin E3 ligases and their rewiring by viral factors
Q90168339E3 ligase ASB8 promotes porcine reproductive and respiratory syndrome virus proliferation by stabilizing the viral Nsp1α protein and degrading host IKKβ kinase
Q64097298Gonadotropin regulation of ankyrin-repeat and SOCS-box protein 9 (ASB9) in ovarian follicles and identification of binding partners
Q35143308How the ankyrin and SOCS box protein, ASB9, binds to creatine kinase
Q35152151Insights into Cullin-RING E3 ubiquitin ligase recruitment: structure of the VHL-EloBC-Cul2 complex
Q42382118Model of the Ankyrin and SOCS Box Protein, ASB9, E3 Ligase Reveals a Mechanism for Dynamic Ubiquitin Transfer.
Q51203293Oxygen poisoning in various mammalian species and the possible role of gamma-aminobutyric acid metabolism
Q34043797Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation
Q26749274The role of cullin 5-containing ubiquitin ligases
Q38863670Working your SOCS off: The role of ASB10 and protein degradation pathways in glaucoma

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