| scholarly article | Q13442814 |
| P50 | author | Matthieu Le Gallo | Q50642905 |
| Nigel J O'Neil | Q55364210 | ||
| James C Mullikin | Q65054916 | ||
| P2093 | author name string | Andrew K Godwin | |
| Daphne W Bell | |||
| Dennis C Sgroi | |||
| Jessica C Price | |||
| Maria J Merino | |||
| Meghan L Rudd | |||
| Nancy F Hansen | |||
| Suiyuan Zhang | |||
| Philip Hieter | |||
| Mary Ellen Urick | |||
| NIH Intramural Sequencing Center (NISC) Comparative Sequencing Program | |||
| Andrea J O'Hara | |||
| Bryant M England | |||
| P2860 | cites work | Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex | Q22004265 |
| Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4 | Q24294656 | ||
| Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1 | Q24303428 | ||
| Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma | Q24337664 | ||
| ARID1A mutations in endometriosis-associated ovarian carcinomas | Q24610484 | ||
| Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer | Q24616117 | ||
| Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer | Q24633517 | ||
| The Catalogue of Somatic Mutations in Cancer (COSMIC) | Q24653244 | ||
| Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 | Q27860674 | ||
| Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources | Q27860739 | ||
| The transcriptional coactivators p300 and CBP are histone acetyltransferases | Q27860843 | ||
| The consensus coding sequences of human breast and colorectal cancers | Q27861035 | ||
| Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists | Q28131785 | ||
| Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma | Q28188670 | ||
| hCDC4 gene mutations in endometrial cancer | Q28218344 | ||
| Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer | Q28251814 | ||
| Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome | Q28262110 | ||
| Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators | Q28267500 | ||
| The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities | Q28286772 | ||
| Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma | Q28292742 | ||
| The genetic landscape of the childhood cancer medulloblastoma | Q28301196 | ||
| DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors | Q28303693 | ||
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| The mutational landscape of lethal castration-resistant prostate cancer | Q29614634 | ||
| NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities | Q29615750 | ||
| Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes | Q29615757 | ||
| FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation | Q29616127 | ||
| Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma | Q29616862 | ||
| Aneuploidy predicts outcome in patients with endometrial carcinoma and is related to lack of CDH13 hypermethylation. | Q33339834 | ||
| The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage | Q33678587 | ||
| A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage | Q33715275 | ||
| Theories of endometrial carcinogenesis: a multidisciplinary approach | Q33886758 | ||
| Mutant chromatin remodeling protein SMARCAL1 causes Schimke immuno-osseous dysplasia. | Q34110155 | ||
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| VarSifter: visualizing and analyzing exome-scale sequence variation data on a desktop computer | Q34115271 | ||
| Cancer biology and NuRD: a multifaceted chromatin remodelling complex | Q34148512 | ||
| Systematic comparison of three genomic enrichment methods for massively parallel DNA sequencing | Q34153640 | ||
| Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome | Q34257013 | ||
| Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses. | Q34393919 | ||
| Uterine papillary serous and clear cell carcinomas predict for poorer survival compared to grade 3 endometrioid corpus cancers | Q34497057 | ||
| ATP-dependent chromatin remodeling: genetics, genomics and mechanisms | Q34627244 | ||
| A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas | Q34694344 | ||
| Mutation and loss of expression of ARID1A in uterine low-grade endometrioid carcinoma | Q34798932 | ||
| Somatic mutations of PPP2R1A in ovarian and uterine carcinomas | Q34805570 | ||
| Specific targeting and constitutive association of histone deacetylase complexes during transcriptional repression | Q35005873 | ||
| PIK3R1 (p85α) is somatically mutated at high frequency in primary endometrial cancer | Q35050913 | ||
| Predicting the functional impact of protein mutations: application to cancer genomics | Q35224321 | ||
| ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers | Q35501591 | ||
| Drug-sensitive FGFR2 mutations in endometrial carcinoma | Q36735178 | ||
| CHD proteins: a diverse family with strong ties | Q36916655 | ||
| Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma | Q37284612 | ||
| Molecular alterations of EGFR and PIK3CA in uterine serous carcinoma | Q37349875 | ||
| Use of mutation profiles to refine the classification of endometrial carcinomas. | Q37612253 | ||
| Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder | Q37730596 | ||
| Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7. | Q39582682 | ||
| Genomic and functional evidence for an ARID1A tumor suppressor role | Q40134611 | ||
| Uterine papillary serous carcinoma: a highly malignant form of endometrial adenocarcinoma | Q40342686 | ||
| Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas | Q42816041 | ||
| Comment on "The consensus coding sequences of human breast and colorectal cancers". | Q47597226 | ||
| Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas | Q60338734 | ||
| Gene amplification and expression of the steroid receptor coactivator SRC3 (AIB1) in sporadic breast and endometrial carcinomas | Q73886723 | ||
| Exome sequencing of liver fluke-associated cholangiocarcinoma | Q84073724 | ||
| Comment on "The consensus coding sequences of human breast and colorectal cancers" | Q94602198 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1310-1315 | |
| P577 | publication date | 2012-10-28 | |
| P1433 | published in | Nature Genetics | Q976454 |
| P1476 | title | Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes | |
| P478 | volume | 44 |
| Q36801631 | A case report and genetic characterization of a massive acinic cell carcinoma of the parotid with delayed distant metastases |
| Q35863143 | A clinically applicable molecular-based classification for endometrial cancers |
| Q38446450 | A global assessment of cancer genomic alterations in epigenetic mechanisms |
| Q38644089 | A simple consensus approach improves somatic mutation prediction accuracy |
| Q47107325 | Aberrant chromatin remodeling in gynecological cancer |
| Q28076086 | Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer |
| Q64235143 | Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma |
| Q111442182 | Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription |
| Q52878923 | Altered primary chromatin structures and their implications in cancer development. |
| Q36177313 | An Old Story Retold: Loss of G1 Control Defines A Distinct Genomic Subtype of Esophageal Squamous Cell Carcinoma |
| Q28485395 | An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development |
| Q34520690 | Architects of the genome: CHD dysfunction in cancer, developmental disorders and neurological syndromes |
| Q41975494 | Association of body mass index with ER, PR and 14-3-3σ expression in tumor and stroma of type I and type II endometrial carcinoma |
| Q44329200 | Association of the chromodomain helicase DNA-binding protein 4 (CHD4) missense variation p.D140E with cancer: potential interaction with smoking |
| Q89427453 | Battle of the sexes: contrasting roles of testis-specific protein Y-encoded (TSPY) and TSPX in human oncogenesis |
| Q37654516 | CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells |
| Q38108666 | CHD4 in the DNA-damage response and cell cycle progression: not so NuRDy now |
| Q91996154 | CHD4 is essential for transcriptional repression and lineage progression in B lymphopoiesis |
| Q55005029 | CHD4 mutations promote endometrial cancer stemness by activating TGF-beta signaling. |
| Q64096094 | CHD4 regulates the DNA damage response and RAD51 expression in glioblastoma |
| Q91497063 | CRL3-SPOP ubiquitin ligase complex suppresses the growth of diffuse large B-cell lymphoma by negatively regulating the MyD88/NF-κB signaling |
| Q41073866 | CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic. |
| Q57029699 | Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments |
| Q35808490 | Chromatin Remodelers: From Function to Dysfunction |
| Q38725254 | Chromatin remodelling and DNA repair genes are frequently mutated in endometrioid endometrial carcinoma |
| Q54942210 | Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy. |
| Q33907067 | Chromatin-regulating proteins as targets for cancer therapy |
| Q30486546 | ChromoHub V2: cancer genomics |
| Q26822979 | Chromodomain helicase DNA-binding proteins in stem cells and human developmental diseases |
| Q60909474 | Class I Phosphoinositide 3-Kinase /p110α and /p110β Isoforms in Endometrial Cancer |
| Q38215703 | Classification of endometrial carcinoma: more than two types |
| Q92461143 | Clinical actionability of molecular targets in endometrial cancer |
| Q55314343 | Clinical impact of endometrial cancer stratified by genetic mutational profiles, POLE mutation, and microsatellite instability. |
| Q91044841 | Clinically relevant molecular subtypes and genomic alteration-independent differentiation in gynecologic carcinosarcoma |
| Q34768482 | Comparing somatic mutation-callers: beyond Venn diagrams |
| Q36096044 | Comprehensive Analysis of the Transcriptional and Mutational Landscape of Follicular and Papillary Thyroid Cancers. |
| Q26747274 | Cullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic Implications |
| Q92218177 | DAXX in cancer: phenomena, processes, mechanisms and regulation |
| Q31120836 | Data on affected cancer-related genes in pediatric t(12;21)-positive acute lymphoblastic leukemia patients harboring unbalanced der(6)t(X;6) translocations |
| Q29147465 | De Novo Mutations in CHD4, an ATP-Dependent Chromatin Remodeler Gene, Cause an Intellectual Disability Syndrome with Distinctive Dysmorphisms |
| Q89936646 | De Novo Variants in SPOP Cause Two Clinically Distinct Neurodevelopmental Disorders |
| Q35010007 | Decreased expression of nuclear p300 is associated with disease progression and worse prognosis of melanoma patients |
| Q41613690 | Decreased expression of speckle-type POZ protein for the prediction of poor prognosis in patients with non-small cell lung cancer |
| Q30278581 | Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis |
| Q33646049 | Differential expression and sex chromosome association of CHD3/4 and CHD5 during spermatogenesis |
| Q49377046 | Double duty: ZMYND8 in the DNA damage response and cancer |
| Q36258125 | Dual HER2/PIK3CA Targeting Overcomes Single-Agent Acquired Resistance in HER2-Amplified Uterine Serous Carcinoma Cell Lines In Vitro and In Vivo |
| Q28086796 | Dysregulation of ubiquitin ligases in cancer |
| Q47260412 | EZH2-, CHD4-, and IDH-linked epigenetic perturbation and its association with survival in glioma patients |
| Q38074214 | Early stage uterine serous carcinoma: management updates and genomic advances |
| Q35847336 | Effect of Next-Generation Exome Sequencing Depth for Discovery of Diagnostic Variants |
| Q35274529 | Endometrial cancer-associated mutants of SPOP are defective in regulating estrogen receptor-α protein turnover |
| Q38852405 | Endometrial cancer: Not your grandmother's cancer |
| Q26766149 | Epigenetic modulators, modifiers and mediators in cancer aetiology and progression |
| Q39317584 | Epigenetics in endometrial carcinogenesis - part 2: histone modifications, chromatin remodeling and noncoding RNAs. |
| Q38709544 | Epigenomic regulation of oncogenesis by chromatin remodeling |
| Q33872622 | Epithelial-to-Mesenchymal Transition in the Female Reproductive Tract: From Normal Functioning to Disease Pathology. |
| Q50035113 | Evolving Roles of Histologic Evaluation and Molecular/Genomic Profiling in the Management of Endometrial Cancer |
| Q54346071 | Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex. |
| Q34791339 | Expression of the dermatomyositis autoantigen transcription intermediary factor 1γ in regenerating muscle. |
| Q37375225 | FBXW7 is involved in the acquisition of the malignant phenotype in epithelial ovarian tumors |
| Q38115209 | Familial rhabdoid tumour 'avant la lettre'--from pathology review to exome sequencing and back again |
| Q45228114 | Frequent CCNE1 amplification in endometrial intraepithelial carcinoma and uterine serous carcinoma |
| Q57116830 | Functional roles of Speckle-Type Poz (SPOP) Protein in Genomic stability |
| Q34779117 | Gene expression analysis of early stage endometrial cancers reveals unique transcripts associated with grade and histology but not depth of invasion |
| Q36742481 | Genetic Diversity in Normal Cell Populations is the Earliest Stage of Oncogenesis Leading to Intra-Tumor Heterogeneity |
| Q47951105 | Genetic alterations in endometrial cancer by targeted next-generation sequencing |
| Q34434773 | Genetic landscape of esophageal squamous cell carcinoma |
| Q33598001 | Genome-wide analysis of gynecologic cancer: The Cancer Genome Atlas in ovarian and endometrial cancer |
| Q36059501 | Genomic Copy Number Variation Affecting Genes Involved in the Cell Cycle Pathway: Implications for Somatic Mosaicism |
| Q35160677 | Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes |
| Q36454484 | Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma |
| Q35266369 | Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma |
| Q26997399 | Genomic landscape of human papillomavirus-associated cancers |
| Q40158003 | Germline Genetic Variants and Lung Cancer Survival in African Americans |
| Q36917944 | High Expression of miR-532-5p, a Tumor Suppressor, Leads to Better Prognosis in Ovarian Cancer Both In Vivo and In Vitro. |
| Q90192347 | High Prevalence of Alterations in DNA Mismatch Repair Genes of Lynch Syndrome in Pediatric Patients with Adrenocortical Tumors Carrying a Germline Mutation on TP53 |
| Q37011857 | Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles |
| Q36335903 | Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer |
| Q47826961 | Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair. |
| Q46914982 | Hybridization alters spontaneous mutation rates in a parent-of-origin-dependent fashion in Arabidopsis. |
| Q33572253 | Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene. |
| Q85493415 | Identification of potential therapeutic targets by molecular profiling of 628 cases of uterine serous carcinoma |
| Q30252086 | Idiopathic Inflammatory Myopathies and Malignancy: a Comprehensive Review |
| Q89378602 | In vitro effects of FBXW7 mutation in serous endometrial cancer: Increased levels of potentially druggable proteins and sensitivity to SI-2 and dinaciclib |
| Q37082531 | In-depth molecular profiling of the biphasic components of uterine carcinosarcomas |
| Q28303563 | Inactivating CUX1 mutations promote tumorigenesis |
| Q30980125 | Inferring pathway dysregulation in cancers from multiple types of omic data |
| Q28289962 | Integrated genomic characterization of endometrial carcinoma |
| Q36520447 | Inter- and intra-patient clonal and subclonal heterogeneity of chronic lymphocytic leukaemia: evidences from circulating and lymph nodal compartments. |
| Q38094260 | Interplay between the cancer genome and epigenome |
| Q91911974 | Interpretation of somatic POLE mutations in endometrial carcinoma |
| Q36887594 | Laminin C1 expression by uterine carcinoma cells is associated with tumor progression |
| Q34169464 | Landscape of genomic alterations in cervical carcinomas |
| Q36637663 | Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma |
| Q90240271 | LncRNA ADAMTS9-AS2 suppresses the proliferation of gastric cancer cells and the tumorigenicity of cancer stem cells through regulating SPOP |
| Q36545494 | Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations. |
| Q52372086 | Loss of ARID1A Expression Correlates With Tumor Differentiation and Tumor Progression Stage in Pancreatic Ductal Adenocarcinoma. |
| Q28537973 | MBD3 localizes at promoters, gene bodies and enhancers of active genes |
| Q38747872 | Marked for death: targeting epigenetic changes in cancer |
| Q31114377 | Meta-dimensional data integration identifies critical pathways for susceptibility, tumorigenesis and progression of endometrial cancer |
| Q38998812 | MiR-31 is an independent prognostic factor and functions as an oncomir in cervical cancer via targeting ARID1A. |
| Q53214123 | Mitogen-activated protein kinase kinase kinase 4 deficiency in intrahepatic cholangiocarcinoma leads to invasive growth and epithelial-mesenchymal transition. |
| Q37268075 | Molecular Analysis of Mixed Endometrial Carcinomas Shows Clonality in Most Cases. |
| Q38119502 | Molecular cytogenetics: recent developments and applications in cancer. |
| Q42416688 | Molecular pathways: SWI/SNF (BAF) complexes are frequently mutated in cancer--mechanisms and potential therapeutic insights. |
| Q45848384 | Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials |
| Q36782739 | Multiple Weak Linear Motifs Enhance Recruitment and Processivity in SPOP-Mediated Substrate Ubiquitination |
| Q34650735 | Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1 |
| Q87475174 | Mutational landscape of hepatoblastoma goes beyond the Wnt-β-catenin pathway |
| Q33600399 | Mutations of Chromatin Structure Regulating Genes in Human Malignancies |
| Q24596715 | NCG 4.0: the network of cancer genes in the era of massive mutational screenings of cancer genomes |
| Q38965974 | Neratinib shows efficacy in the treatment of HER2/neu amplified uterine serous carcinoma in vitro and in vivo |
| Q28071864 | New concepts for an old problem: the diagnosis of endometrial hyperplasia |
| Q51032285 | Next-Generation Sequencing. |
| Q34026696 | Novel genetic targets in endometrial cancer |
| Q36393068 | Novel kinase fusion transcripts found in endometrial cancer |
| Q47667287 | Nucleosome-Chd1 structure and implications for chromatin remodelling |
| Q47956425 | Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors. |
| Q34350701 | Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles |
| Q90987627 | PI3K oncogenic mutations mediate resistance to afatinib in HER2/neu overexpressing gynecological cancers |
| Q44448363 | PIK3CA missense mutation is associated with unfavorable outcome in grade 3 endometrioid carcinoma but not in serous endometrial carcinoma. |
| Q36295013 | PIK3CA oncogenic mutations represent a major mechanism of resistance to trastuzumab in HER2/neu overexpressing uterine serous carcinomas |
| Q54351302 | POLE exonuclease domain mutation predicts long progression-free survival in grade 3 endometrioid carcinoma of the endometrium. |
| Q92864431 | PP2A: A Promising Biomarker and Therapeutic Target in Endometrial Cancer |
| Q35691011 | PTEN Expression as a Predictor of Response to Focal Adhesion Kinase Inhibition in Uterine Cancer |
| Q59510109 | Parental age affects somatic mutation rates in the progeny of flowering plants |
| Q36974742 | Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway |
| Q34994583 | Prognostic significance of POLE proofreading mutations in endometrial cancer. |
| Q38869756 | Properties and Clinical Relevance of Speckle-Type POZ Protein in Human Colorectal Cancer |
| Q34637940 | Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer |
| Q35203134 | Protein domain-level landscape of cancer-type-specific somatic mutations |
| Q52581831 | RNA-seq Reveals the Overexpression of IGSF9 in Endometrial Cancer. |
| Q55008423 | Racial differences in endometrial cancer molecular portraits in The Cancer Genome Atlas. |
| Q39051429 | Reduced expression of the chromatin remodeling gene ARID1A enhances gastric cancer cell migration and invasion via downregulation of E-cadherin transcription |
| Q41472107 | Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis |
| Q39421725 | Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for therapy |
| Q87013866 | Reproducibility of histological cell type in high-grade endometrial carcinoma |
| Q35173275 | Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4. |
| Q34340537 | Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma. |
| Q35012352 | Roles of F-box proteins in cancer |
| Q52329737 | SALL1 functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex. |
| Q36278928 | SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase |
| Q91828572 | SPOP Regulates The Biological Mechanism Of Ovarian Cancer Cells Through The Hh Signaling Pathway |
| Q91713061 | SPOP and cancer: a systematic review |
| Q58772309 | SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability |
| Q90781287 | SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG |
| Q92481994 | SPOP targets oncogenic protein ZBTB3 for destruction to suppress endometrial cancer |
| Q48102860 | SPOP tips the balance of BETs in cancer |
| Q47435129 | SPOP-mediated degradation of BRD4 dictates cellular sensitivity to BET inhibitors |
| Q26998657 | SWI/SNF chromatin remodeling complexes and cancer |
| Q28269618 | SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2 |
| Q34981653 | Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination. |
| Q34765551 | Sequencing of candidate chromosome instability genes in endometrial cancers reveals somatic mutations in ESCO1, CHTF18, and MRE11A |
| Q42377155 | Signatures of positive selection reveal a universal role of chromatin modifiers as cancer driver genes |
| Q90630673 | Somatic genetic alterations in synchronous and metachronous low-grade serous tumours and high-grade carcinomas of the adnexa |
| Q51011096 | Somatic mutation of SPOP tumor suppressor gene is rare in breast, lung, liver cancers, and acute leukemias. |
| Q48170773 | Somatic mutation profiles of clear cell endometrial tumors revealed by whole exome and targeted gene sequencing |
| Q47272138 | Speckle-Type POZ Protein Down-Regulates Matrix Metalloproteinase 2 Expression via Sp1/PI3K/Akt Signaling Pathway in Colorectal Cancer |
| Q60936355 | Speckle-type POZ protein functions as a tumor suppressor in non-small cell lung cancer due to DNA methylation |
| Q52661725 | Speckle-type POZ protein is negatively associated with malignancies and inhibits cell proliferation and migration in liver cancer. |
| Q41836192 | Speckle-type POZ protein, SPOP, is involved in the DNA damage response. |
| Q35942306 | Stability of HIB-Cul3 E3 ligase adaptor HIB Is Regulated by Self-degradation and Availability of Its Substrates |
| Q36931649 | Systematic Evaluation of Sanger Validation of Next-Generation Sequencing Variants |
| Q36009016 | Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles |
| Q37381834 | TP53 Mutational Spectrum in Endometrioid and Serous Endometrial Cancers |
| Q59326828 | TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression |
| Q47659136 | TSPYL Family Regulates CYP17A1 and CYP3A4 Expression: Potential Mechanism Contributing to Abiraterone Response in Metastatic Castration-Resistant Prostate Cancer. |
| Q90524104 | TSPYL2 is a novel regulator of SIRT1 and p300 activity in response to DNA damage |
| Q90599256 | Targeted Next-Generation Sequencing Identifies Actionable Targets in Estrogen Receptor Positive and Estrogen Receptor Negative Endometriod Endometrial Cancer |
| Q57169683 | Targeted Therapies in Type II Endometrial Cancers: Too Little, but Not Too Late |
| Q54188782 | Targeted mutation analysis of endometrial clear cell carcinoma. |
| Q37699264 | Targeted therapy in uterine serous carcinoma: an aggressive variant of endometrial cancer |
| Q92179985 | Targeting epigenetic modifications in cancer therapy: erasing the roadmap to cancer |
| Q34729807 | Taselisib, a selective inhibitor of PIK3CA, is highly effective on PIK3CA-mutated and HER2/neu amplified uterine serous carcinoma in vitro and in vivo |
| Q37735355 | The Chromodomain Helicase DNA-Binding Chromatin Remodelers: Family Traits that Protect from and Promote Cancer |
| Q47757165 | The FOXA2 transcription factor is frequently somatically mutated in uterine carcinosarcomas and carcinomas. |
| Q28292392 | The SWI/SNF genetic blockade: effects in cell differentiation, cancer and developmental diseases |
| Q64246928 | The X-linked tumor suppressor TSPX downregulates cancer-drivers/oncogenes in prostate cancer in a C-terminal acidic domain dependent manner |
| Q38717520 | The Y-located proto-oncogene TSPY exacerbates and its X-homologue TSPX inhibits transactivation functions of androgen receptor and its constitutively active variants |
| Q90437578 | The association of speckle-type POZ protein with lymph node metastasis and prognosis in cancer patients: A meta-analysis |
| Q38090427 | The diverse heterogeneity of molecular alterations in prostate cancer identified through next-generation sequencing |
| Q94474488 | The diverse roles of SPOP in prostate cancer and kidney cancer |
| Q34026976 | The emerging genomic landscape of endometrial cancer |
| Q92413024 | The emerging role of SPOP protein in tumorigenesis and cancer therapy |
| Q34430637 | The emerging role of speckle-type POZ protein (SPOP) in cancer development |
| Q26865554 | The estrogen receptor joins other cancer biomarkers as a predictor of outcome |
| Q30580509 | The mutational landscape of chromatin regulatory factors across 4,623 tumor samples |
| Q28084466 | The mutational landscape of endometrial cancer |
| Q36692354 | The nucleosome remodeling and deacetylase complex in development and disease |
| Q34382912 | The promise of whole-exome sequencing in medical genetics |
| Q36309431 | Tumor suppressor SPOP mediates the proteasomal degradation of progesterone receptors (PRs) in breast cancer cells |
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| Q46609299 | Ubiquitin ligases in oncogenic transformation and cancer therapy |
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| Q50600342 | Unique features of mutations revealed by sequentially reprogrammed induced pluripotent stem cells. |
| Q102053029 | Uterine carcinosarcoma: Contemporary clinical summary, molecular updates, and future research opportunity |
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| Q101451083 | Uterine serous carcinoma: Molecular features, clinical management, and new and future therapies |
| Q34732898 | Uterine superficial serous carcinomas and extensive serous endometrial intraepithelial carcinomas: clinicopathological analysis of 6 patients |
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| Q37323204 | Whole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma. |
| Q35195877 | Whole-exome sequencing of endometriosis identifies frequent alterations in genes involved in cell adhesion and chromatin-remodeling complexes |
| Q38728073 | Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma |
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