scholarly article | Q13442814 |
P2093 | author name string | P Zhang | |
Y Zhang | |||
H Huang | |||
J Ma | |||
L Yu | |||
X Jin | |||
Y Tang | |||
J Peng | |||
C Wang | |||
K Gao | |||
J An | |||
Y Dong | |||
Q Yan | |||
R Wumaier | |||
P2860 | cites work | The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling | Q52514375 |
BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase | Q53633362 | ||
Whole abdominal radiotherapy in the adjuvant treatment of patients with stage III and IV endometrial cancer: a gynecologic oncology group study | Q81780938 | ||
Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1 | Q24303428 | ||
Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase | Q24336527 | ||
Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase | Q24529056 | ||
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer | Q24616117 | ||
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases | Q27657740 | ||
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 | Q27860674 | ||
Integrated genomic characterization of endometrial carcinoma | Q28289962 | ||
Steroid hormone receptors: many actors in search of a plot | Q29618397 | ||
The emerging genomic landscape of endometrial cancer | Q34026976 | ||
Estrogen receptor: current understanding of its activation and modulation | Q34120680 | ||
Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses. | Q34393919 | ||
Destruction of full-length androgen receptor by wild-type SPOP, but not prostate-cancer-associated mutants | Q35181646 | ||
Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes | Q36447819 | ||
Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma | Q36637663 | ||
Proteasome-dependent degradation of the human estrogen receptor | Q37160826 | ||
The emerging family of CULLIN3-RING ubiquitin ligases (CRL3s): cellular functions and disease implications. | Q37163747 | ||
Pin1 modulates ERα levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation | Q37274658 | ||
Rational management of endocrine resistance in breast cancer: a comprehensive review of estrogen receptor biology, treatment options, and future directions. | Q37279990 | ||
Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer. | Q37373844 | ||
Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase | Q37482039 | ||
SPOP mutations in prostate cancer across demographically diverse patient cohorts. | Q37584305 | ||
Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover | Q37599824 | ||
Links between oestrogen receptor activation and proteolysis: relevance to hormone-regulated cancer therapy. | Q38186042 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P304 | page(s) | e1687 | |
P577 | publication date | 2015-03-12 | |
P1433 | published in | Cell Death and Disease | Q2197222 |
P1476 | title | Endometrial cancer-associated mutants of SPOP are defective in regulating estrogen receptor-α protein turnover | |
P478 | volume | 6 |
Q91497063 | CRL3-SPOP ubiquitin ligase complex suppresses the growth of diffuse large B-cell lymphoma by negatively regulating the MyD88/NF-κB signaling |
Q26747274 | Cullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic Implications |
Q38733838 | Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6. |
Q28086796 | Dysregulation of ubiquitin ligases in cancer |
Q36556179 | Effects of 8-Prenylnaringenin and Whole-Body Vibration Therapy on a Rat Model of Osteopenia |
Q47413250 | Functional analysis of Cullin 3 E3 ligases in tumorigenesis. |
Q37011857 | Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles |
Q45848384 | Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials |
Q51032285 | Next-Generation Sequencing |
Q40758288 | SPOP Regulates Endometrial Stromal Cell Decidualization in Mice |
Q91828572 | SPOP Regulates The Biological Mechanism Of Ovarian Cancer Cells Through The Hh Signaling Pathway |
Q91713061 | SPOP and cancer: a systematic review |
Q90781287 | SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG |
Q92481994 | SPOP targets oncogenic protein ZBTB3 for destruction to suppress endometrial cancer |
Q47435129 | SPOP-mediated degradation of BRD4 dictates cellular sensitivity to BET inhibitors |
Q60936355 | Speckle-type POZ protein functions as a tumor suppressor in non-small cell lung cancer due to DNA methylation |
Q36009016 | Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles |
Q92413024 | The emerging role of SPOP protein in tumorigenesis and cancer therapy |
Q36309431 | Tumor suppressor SPOP mediates the proteasomal degradation of progesterone receptors (PRs) in breast cancer cells |
Q33906824 | Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells |
Q53078772 | Uterine function in the mouse requires speckle-type poz protein. |
Search more.