| P2093 | author name string | Monica Venere | |
| | Belinda Willard | |
| | Matthew K Summers | |
| | Debjani Pal | |
| | Abbey L Messina | |
| | Adrian E Torres | |
| | Andrew S Dickson | |
| | Benjamin R Stromberg | |
| | Kuntal De | |
| P2860 | cites work | Identification of the receptor component of the IkappaBalpha-ubiquitin ligase | Q22008569 |
| | SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response | Q24298620 |
| | Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress | Q24307983 |
| | NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint | Q24313589 |
| | The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint | Q24317772 |
| | ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1 | Q24550952 |
| | Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis | Q24551182 |
| | Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint | Q24604730 |
| | The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro | Q24608829 |
| | Mammalian Cdh1/Fzr mediates its own degradation | Q24610309 |
| | Control of cell growth by the SCF and APC/C ubiquitin ligases | Q24647543 |
| | Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer | Q24648025 |
| | USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin | Q24652867 |
| | The anaphase-promoting complex/cyclosome (APC/C) is required for rereplication control in endoreplication cycles | Q24655067 |
| | CellProfiler: image analysis software for identifying and quantifying cell phenotypes | Q24676898 |
| | Insights into APC/C: from cellular function to diseases and therapeutics | Q26740196 |
| | Atomic structure of the APC/C and its mechanism of protein ubiquitination | Q27316585 |
| | The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma. | Q27324657 |
| | Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14. | Q27930227 |
| | CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. | Q27930914 |
| | Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex | Q27933305 |
| | Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage | Q28182301 |
| | SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase | Q28234989 |
| | Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis | Q39782770 |
| | Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence. | Q40079322 |
| | CHIR-124, a novel potent inhibitor of Chk1, potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo | Q40178792 |
| | Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway. | Q40378903 |
| | Chk1-dependent S-M checkpoint delay in vertebrate cells is linked to maintenance of viable replication structures. | Q40474908 |
| | Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex | Q40919505 |
| | The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell. | Q40967633 |
| | Skp1-Cul1-F-box ubiquitin ligase (SCF(βTrCP))-mediated destruction of the ubiquitin-specific protease USP37 during G2-phase promotes mitotic entry | Q41309461 |
| | CRL4(CDT2) targets CHK1 for PCNA-independent destruction | Q41840512 |
| | Chk1 regulates the density of active replication origins during the vertebrate S phase. | Q41847676 |
| | PLK1 Activation in Late G2 Sets Up Commitment to Mitosis | Q47316004 |
| | Genomic stability and tumour suppression by the APC/C cofactor Cdh1. | Q53471624 |
| | Proteolysis of CDH1 enhances susceptibility to UV radiation-induced apoptosis. | Q53507320 |
| | The ubiquitin ligase APC(Cdh1) is required to maintain genome integrity in primary human cells. | Q53534176 |
| | Who guards the guardian? Mechanisms that restrain APC/C during the cell cycle | Q57043849 |
| | Hyperphosphorylation of CDH1 in Glioblastoma Cancer Stem Cells Attenuates APC/CCDH1 Activity and Pharmacologic Inhibition of APC/CCDH1/CDC20 Compromises Viability | Q91623081 |
| | E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition | Q92689915 |
| | An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication | Q92824007 |
| | Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress | Q28255529 |
| | Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery | Q28260190 |
| | ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage | Q28266407 |
| | Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1 | Q28282074 |
| | Checkpoint kinase 1 in DNA damage response and cell cycle regulation | Q28287480 |
| | Roles of Chk1 in cell biology and cancer therapy | Q28289548 |
| | Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells | Q28364060 |
| | Mitotic regulation of the APC activator proteins CDC20 and CDH1 | Q28631628 |
| | Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems | Q29026493 |
| | The APC/C inhibitor, Emi1, is essential for prevention of rereplication | Q30442630 |
| | Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1). | Q30480596 |
| | Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability | Q33917704 |
| | A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression | Q33968253 |
| | The anaphase-promoting complex: it's not just for mitosis any more. | Q34147374 |
| | Ubiquitin ligases and cell cycle control | Q34333159 |
| | Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase | Q34563205 |
| | The Role of Cdh1p in Maintaining Genomic Stability in Budding Yeast | Q34618699 |
| | Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors. | Q35757254 |
| | The APC/C Ubiquitin Ligase: From Cell Biology to Tumorigenesis | Q35971862 |
| | Evidence that the ATR/Chk1 pathway maintains normal replication fork progression during unperturbed S phase. | Q36592000 |
| | Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteins | Q36703456 |
| | Conformational Change of Human Checkpoint Kinase 1 (Chk1) Induced by DNA Damage | Q37065840 |
| | Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways | Q37262174 |
| | A Cds1-mediated checkpoint protects the MBF activator Rep2 from ubiquitination by anaphase-promoting complex/cyclosome-Ste9 at S-phase arrest in fission yeast. | Q37334039 |
| | SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression. | Q37340307 |
| | DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress | Q37418404 |
| | The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression | Q37614211 |
| | APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity | Q37799221 |
| | Coordination of cell growth and division by the ubiquitin-proteasome system. | Q38006275 |
| | Selective Inhibition of Parallel DNA Damage Response Pathways Optimizes Radiosensitization of Glioblastoma Stem-like Cells | Q38843091 |
| | ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress | Q39062429 |
| | Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7. | Q39152605 |
| | APC/C and SCF(cyclin F) Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry | Q39366368 |
| | Dynamic ubiquitin signaling in cell cycle regulation. | Q39419310 |
| P4510 | describes a project that uses | CellProfiler | Q5058134 |
| P433 | issue | 4 | |
| P304 | page(s) | 298 | |
| P577 | publication date | 2020-04-28 | |
| P1433 | published in | Cell Death and Disease | Q2197222 |
| P1476 | title | Chk1-mediated phosphorylation of Cdh1 promotes the SCFβTRCP-dependent degradation of Cdh1 during S-phase and efficient cell-cycle progression | |
| P478 | volume | 11 | |