| scholarly article | Q13442814 |
| P50 | author | Martin Eilers | Q37383629 |
| P2093 | author name string | Christina Schülein | |
| Nikita Popov | |||
| Laura A Jaenicke | |||
| P2860 | cites work | Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach | Q24297923 |
| SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response | Q24298620 | ||
| Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase | Q24306203 | ||
| The ubiquitin-specific protease USP28 is required for MYC stability | Q24308568 | ||
| Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma | Q24311457 | ||
| Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery | Q24311665 | ||
| Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells | Q24321642 | ||
| Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1 | Q24323957 | ||
| Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7 | Q24337643 | ||
| The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro | Q24608829 | ||
| Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer | Q24648025 | ||
| Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series | Q24655287 | ||
| c-Myc accelerates S-phase and requires WRN to avoid replication stress | Q27347951 | ||
| Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination | Q27645983 | ||
| Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry | Q28115829 | ||
| Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha | Q28144122 | ||
| Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines | Q28188140 | ||
| Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100 | Q28216699 | ||
| Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress | Q28255529 | ||
| The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation | Q28280330 | ||
| Non-transcriptional control of DNA replication by c-Myc | Q28307758 | ||
| Inference of cell cycle-dependent proteolysis by laser scanning cytometry | Q33424132 | ||
| The MYC protein activates transcription of the alpha-prothymosin gene. | Q33515603 | ||
| Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome | Q33859404 | ||
| The myc oncogene: MarvelouslY Complex | Q34555987 | ||
| BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo. | Q34575151 | ||
| Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages. | Q34617875 | ||
| Loss of protooncogene c-Myc function impedes G1 phase progression both before and after the restriction point | Q34812632 | ||
| The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation | Q34835596 | ||
| Reconstructing MYC. | Q35120942 | ||
| Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. | Q35204486 | ||
| Plx1 is required for chromosomal DNA replication under stressful conditions | Q36491053 | ||
| Myc's broad reach | Q37299032 | ||
| The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain. | Q37402856 | ||
| Facilitating replication under stress: an oncogenic function of MYC? | Q37492244 | ||
| SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities | Q40243716 | ||
| Skp2 regulates Myc protein stability and activity | Q40644685 | ||
| Growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line | Q40758214 | ||
| Molecular dissection of the interactions among IkappaBalpha, FWD1, and Skp1 required for ubiquitin-mediated proteolysis of IkappaBalpha | Q40924424 | ||
| c-Myc depletion inhibits proliferation of human tumor cells at various stages of the cell cycle | Q42115767 | ||
| Dual regulation of the met4 transcription factor by ubiquitin-dependent degradation and inhibition of promoter recruitment | Q44084606 | ||
| c-myc oncogene protein synthesis is independent of the cell cycle in human and avian cells | Q44259494 | ||
| The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription | Q44455864 | ||
| C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia | Q46362458 | ||
| Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34. | Q46711534 | ||
| Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas | Q55670934 | ||
| Ubiquitin transfer from the E2 perspective: why is UbcH5 so promiscuous? | Q79546828 | ||
| A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination | Q82857335 | ||
| P433 | issue | 10 | |
| P921 | main subject | ubiquitination | Q33059483 |
| P304 | page(s) | 973-981 | |
| P577 | publication date | 2010-09-19 | |
| P1433 | published in | Nature Cell Biology | Q1574111 |
| P1476 | title | Ubiquitylation of the amino terminus of Myc by SCF(β-TrCP) antagonizes SCF(Fbw7)-mediated turnover | |
| P478 | volume | 12 |
| Q30844250 | A design principle underlying the paradoxical roles of E3 ubiquitin ligases |
| Q47441648 | A partnership with the proteasome; the destructive nature of GSK3. |
| Q57666020 | A systems-wide screen identifies substrates of the SCF TrCP ubiquitin ligase |
| Q21128783 | ABC transporter functions as a pacemaker for sequestration of plant glucosides in leaf beetles |
| Q35236066 | BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues |
| Q37040833 | CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer |
| Q47839883 | CRL4 antagonizes SCFFbxo7-mediated turnover of cereblon and BK channel to regulate learning and memory |
| Q30370484 | CUL4-DDB1-CDT2 E3 Ligase Regulates the Molecular Clock Activity by Promoting Ubiquitination-Dependent Degradation of the Mammalian CRY1 |
| Q24321406 | Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm |
| Q35626088 | Competition between Decapping Complex Formation and Ubiquitin-Mediated Proteasomal Degradation Controls Human Dcp2 Decapping Activity |
| Q45209344 | Connectivity mapping identifies HDAC inhibitors for the treatment of t(4;11)-positive infant acute lymphoblastic leukemia |
| Q54453884 | Cystathionase mediates senescence evasion in melanocytes and melanoma cells |
| Q35668793 | DNA Damage Regulates Translation through β-TRCP Targeting of CReP |
| Q38677243 | Deubiquitinating c-Myc: USP36 steps up in the nucleolus |
| Q89674021 | Direct Phosphorylation and Stabilization of MYC by Aurora B Kinase Promote T-cell Leukemogenesis |
| Q24307490 | Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity |
| Q38636582 | Dose-dependent regulation of target gene expression and cell proliferation by c-Myc levels |
| Q36148000 | E3 Ubiquitin Ligase RLIM Negatively Regulates c-Myc Transcriptional Activity and Restrains Cell Proliferation |
| Q35968349 | ELL targets c-Myc for proteasomal degradation and suppresses tumour growth |
| Q47717403 | Elucidating the rapid action of 2-(2-chlorophenyl)ethylbiguanide on HT-29 cells under a serum- and glucose-deprived condition |
| Q90746433 | F-box proteins and cancer: an update from functional and regulatory mechanism to therapeutic clinical prospects |
| Q24321496 | FBXL21 Regulates Oscillation of the Circadian Clock through Ubiquitination and Stabilization of Cryptochromes |
| Q40972142 | FBXO32 Targets c-Myc for Proteasomal Degradation and Inhibits c-Myc Activity |
| Q58797685 | FBXW7: a critical tumor suppressor of human cancers |
| Q38625813 | Lysine-52 stabilizes the MYC oncoprotein through an SCF(Fbxw7)-independent mechanism |
| Q24339513 | MEK1 promotes YAP and their interaction is critical for tumorigenesis in liver cancer |
| Q37122738 | MYC Degradation under Low O2 Tension Promotes Survival by Evading Hypoxia-Induced Cell Death |
| Q34083178 | MYC cofactors: molecular switches controlling diverse biological outcomes |
| Q38193043 | MYC degradation |
| Q29619979 | MYC on the Path to Cancer |
| Q59072385 | Mammalian MYC Proteins and Cancer |
| Q92508203 | Max deletion destabilizes MYC protein and abrogates Eµ-Myc lymphomagenesis |
| Q35159280 | Nitric oxide increases lysine 48-linked ubiquitination following arterial injury. |
| Q34742737 | Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3. |
| Q38156100 | Oncoprotein stabilization in brain tumors. |
| Q40272529 | PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription |
| Q51069616 | PKA/Smurf1 signaling-mediated stabilization of Nur77 is required for anticancer drug cisplatin-induced apoptosis |
| Q38448691 | Post-translational control of Myc function during differentiation |
| Q30413042 | Protein Kinase A Regulates MYC Protein through Transcriptional and Post-translational Mechanisms in a Catalytic Subunit Isoform-specific Manner |
| Q36471316 | Protein turnover during in vitro tissue engineering |
| Q37894329 | Proteolytic Control of the Oncoprotein Transcription Factor Myc |
| Q33861057 | RNAi screen identifies a synthetic lethal interaction between PIM1 overexpression and PLK1 inhibition |
| Q35579298 | Regulation of c-Myc protein stability by proteasome activator REGγ |
| Q37962378 | Role of the ubiquitin ligase Fbw7 in cancer progression |
| Q28482220 | Roles of Protein Ubiquitination and Degradation Kinetics in Biological Oscillations |
| Q39743125 | SCFFbl12 Increases p21Waf1/Cip1 Expression Level through Atypical Ubiquitin Chain Synthesis |
| Q38102567 | SCFs in the new millennium |
| Q47616444 | SPSB3 targets SNAIL for degradation in GSK-3β phosphorylation-dependent manner and regulates metastasis |
| Q41039086 | Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP. |
| Q34945490 | Stabilization of Myc through Heterotypic Poly-Ubiquitination by mLANA Is Critical for γ-Herpesvirus Lymphoproliferation |
| Q89767723 | Target gene-independent functions of MYC oncoproteins |
| Q92028662 | Targeting Cancer Stem Cells in Triple-Negative Breast Cancer |
| Q35720003 | Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity |
| Q40512435 | The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ. |
| Q54977707 | The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. |
| Q37468740 | The Smad7-Skp2 complex orchestrates Myc stability, impacting on the cytostatic effect of TGF-β |
| Q45062542 | The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia. |
| Q35229540 | The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc |
| Q35622220 | The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis |
| Q92665751 | The role of aurora A and polo-like kinases in high-risk lymphomas |
| Q33619419 | The role of the human psoralen 4 (hPso4) protein complex in replication stress and homologous recombination |
| Q90093670 | The role of ubiquitination in tumorigenesis and targeted drug discovery |
| Q39356833 | The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity. |
| Q24296476 | The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability |
| Q48000346 | The ubiquitin-proteasome pathway in adult and pediatric brain tumors: biological insights and therapeutic opportunities |
| Q38945828 | The ubiquitin-proteasome system and chromosome 17 in cerebellar granule cells and medulloblastoma subgroups |
| Q37005709 | Translational and post-translational regulation of mouse cation transport regulator homolog 1 |
| Q85682295 | USP37 directly deubiquitinates and stabilizes c-Myc in lung cancer |
| Q26849500 | Ubiquitin on the move: the ubiquitin modification system plays diverse roles in the regulation of endoplasmic reticulum- and plasma membrane-localized proteins |
| Q50134119 | Ubiquitin-conjugating enzyme E2 D1 (Ube2D1) mediates lysine-independent ubiquitination of the E3 ubiquitin ligase March-I. |
| Q91940275 | Writing and erasing MYC ubiquitination and SUMOylation |
| Q52720818 | Zinc finger protein 746 promotes colorectal cancer progression via c-Myc stability mediated by glycogen synthase kinase 3β and F-box and WD repeat domain-containing 7. |
| Q35137658 | β-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells. |
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