| scholarly article | Q13442814 |
| retracted paper | Q45182324 |
| P2093 | author name string | Aleyde Van Eynde | |
| Mathieu Bollen | |||
| Lijs Beke | |||
| Monique Beullens | |||
| Dirk Brehmer | |||
| Cenk Kig | |||
| Johannes T Linders | |||
| P2860 | cites work | Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family | Q21195232 |
| A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability | Q24298271 | ||
| Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3. | Q24306287 | ||
| LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1 | Q24310603 | ||
| Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation | Q24313276 | ||
| Substrate specificity and activity regulation of protein kinase MELK | Q24338012 | ||
| Phosphorylation of a novel zinc-finger-like protein, ZPR9, by murine protein serine/threonine kinase 38 (MPK38) | Q24533606 | ||
| A biomarker that identifies senescent human cells in culture and in aging skin in vivo | Q24562644 | ||
| Chromosome breakage after G2 checkpoint release | Q24683383 | ||
| Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3 | Q27973740 | ||
| Inhibition of spliceosome assembly by the cell cycle-regulated protein kinase MELK and involvement of splicing factor NIPP1 | Q28236635 | ||
| DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2 | Q28254119 | ||
| Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines | Q28297800 | ||
| Murine protein serine/threonine kinase 38 activates apoptosis signal-regulating kinase 1 via Thr 838 phosphorylation | Q28590590 | ||
| Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation | Q28591125 | ||
| Regulating the p53 pathway: in vitro hypotheses, in vivo veritas | Q29615658 | ||
| Post-translational modifications and activation of p53 by genotoxic stresses | Q29615659 | ||
| Bleomycin: new perspectives on the mechanism of action | Q30304641 | ||
| p21 in cancer: intricate networks and multiple activities | Q30436015 | ||
| Tumor-specific activation of the C-JUN/MELK pathway regulates glioma stem cell growth in a p53-dependent manner | Q34044078 | ||
| Visualization of DNA replication in the vertebrate model system DT40 using the DNA fiber technique | Q34069344 | ||
| Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway | Q35021326 | ||
| DNA damage induces phosphorylation of the amino terminus of p53 | Q35199554 | ||
| The intra-S-phase checkpoint affects both DNA replication initiation and elongation: single-cell and -DNA fiber analyses | Q35950241 | ||
| Murine protein serine-threonine kinase 38 activates p53 function through Ser15 phosphorylation | Q36033101 | ||
| Regulation of the p53-MDM2 pathway by 14-3-3 sigma and other proteins. | Q36477042 | ||
| Caenorhabditis elegans PIG-1/MELK acts in a conserved PAR-4/LKB1 polarity pathway to promote asymmetric neuroblast divisions | Q36643905 | ||
| MDMX: from bench to bedside | Q36717697 | ||
| An imperfect G2M checkpoint contributes to chromosome instability following irradiation of S and G2 phase cells | Q36885337 | ||
| The mammalian DNA replication elongation checkpoint: implication of Chk1 and relationship with origin firing as determined by single DNA molecule and single cell analyses | Q36994999 | ||
| Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control | Q37081706 | ||
| Regulation of DNA repair throughout the cell cycle | Q37088926 | ||
| MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells. | Q37098261 | ||
| Beyond ATM: the protein kinase landscape of the DNA damage response | Q37875377 | ||
| Checkpoint control and cancer. | Q37941374 | ||
| New insights into p53 signaling and cancer cell response to DNA damage: implications for cancer therapy | Q38036571 | ||
| DNA damage checkpoints in stem cells, ageing and cancer. | Q38036830 | ||
| Interaction between natural compounds and human topoisomerase I. | Q38056476 | ||
| Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3. | Q38321368 | ||
| The maternal embryonic leucine zipper kinase (MELK) is upregulated in high-grade prostate cancer | Q39286062 | ||
| Resistance of colorectal cancer cells to radiation and 5-FU is associated with MELK expression | Q39497051 | ||
| The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation | Q39776763 | ||
| The changing AMPK expression profile in differentiating mouse skeletal muscle myoblast cells helps confer increasing resistance to apoptosis | Q40237358 | ||
| M-phase MELK activity is regulated by MPF and MAPK. | Q40289655 | ||
| Trypan Blue Exclusion Test of Cell Viability. | Q40924988 | ||
| Maternal embryonic leucine zipper kinase/murine protein serine-threonine kinase 38 is a promising therapeutic target for multiple cancers | Q42808469 | ||
| Maternal embryonic leucine zipper kinase is stabilized in mitosis by phosphorylation and is partially degraded upon mitotic exit | Q43085095 | ||
| Apoptosis induced by adenovirus-mediated p53 gene transfer in human glioma correlates with site-specific phosphorylation | Q43893148 | ||
| Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation | Q44477368 | ||
| The C. elegans MELK ortholog PIG-1 regulates cell size asymmetry and daughter cell fate in asymmetric neuroblast divisions. | Q44846511 | ||
| Thermal denaturation of DNA for immunochemical staining of incorporated bromodeoxyuridine (BrdUrd): critical factors that affect the amount of fluorescence and the shape of BrdUrd/DNA histogram | Q46123354 | ||
| Maternal embryonic leucine zipper kinase transcript abundance correlates with malignancy grade in human astrocytomas. | Q46931943 | ||
| A functional analysis of MELK in cell division reveals a transition in the mode of cytokinesis during Xenopus development. | Q53263078 | ||
| Phosphorylation of a novel zinc-finger-like protein, ZPR9, by murine protein serine/threonine kinase 38 (MPK38) | Q56602584 | ||
| Effect of hydroxyurea and 5-fluorodeoxy-uridine on deoxyribonucleoside triphosphate pools early in phytohemagglutinin-stimulated human lymphocytes | Q72771362 | ||
| P4510 | describes a project that uses | ImageQuant | Q112270642 |
| P433 | issue | 33 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | glioblastoma | Q282142 |
| P1104 | number of pages | 13 | |
| P304 | page(s) | 24200-24212 | |
| P577 | publication date | 2013-07-08 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells | |
| P478 | volume | 288 |
| Q42108657 | CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials |
| Q92068313 | Cloning, tissue distribution, expression pattern, and function of porcine maternal embryonic leucine zipper kinase |
| Q36546013 | Co-expression of mitosis-regulating genes contributes to malignant progression and prognosis in oligodendrogliomas |
| Q38652528 | DNA replication stress and cancer: cause or cure? |
| Q92141525 | Design, synthesis, biological evaluation and molecular modeling of novel 1H-pyrrolo[2,3-b]pyridine derivatives as potential anti-tumor agents |
| Q38466329 | Exploiting replicative stress to treat cancer |
| Q42130307 | Fragment-based discovery of type I inhibitors of maternal embryonic leucine zipper kinase |
| Q60046564 | Gene expression profiling of spontaneously occurring canine mammary tumours: Insight into gene networks and pathways linked to cancer pathogenesis |
| Q36289944 | Genome-wide effects of MELK-inhibitor in triple-negative breast cancer cells indicate context-dependent response with p53 as a key determinant |
| Q91846035 | Inhibition of MELK produces potential anti-tumour effects in bladder cancer by inducing G1/S cell cycle arrest via the ATM/CHK2/p53 pathway |
| Q38941812 | Kinome Profiling Identifies Druggable Targets for Novel Human Cytomegalovirus (HCMV) Antivirals. |
| Q49701324 | MELK expression correlates with tumor mitotic activity but is not required for cancer growth. |
| Q49187608 | MELK is a novel therapeutic target in high-risk neuroblastoma |
| Q37411211 | MELK kinase holds promise as a new radiosensitizing target and biomarker in triple-negative breast cancer |
| Q36275700 | MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells |
| Q35265941 | MELK-a conserved kinase: functions, signaling, cancer, and controversy |
| Q50948001 | MOZ (MYST3, KAT6A) inhibits senescence via the INK4A-ARF pathway. |
| Q55008828 | Maternal Embryonic Leucine Zipper Kinase (MELK) as a Novel Mediator and Biomarker of Radioresistance in Human Breast Cancer. |
| Q41274720 | Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells |
| Q33960305 | Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway |
| Q38497875 | MicroRNAs and cell cycle of malignant glioma |
| Q26738538 | Molecular mechanisms of peritoneal dissemination in gastric cancer |
| Q35068076 | Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia. |
| Q38790859 | Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor |
| Q38706288 | Small molecules inhibit STAT3 activation, autophagy, and cancer cell anchorage-independent growth. |
| Q36332768 | Structure-Based Target-Specific Screening Leads to Small-Molecule CaMKII Inhibitors. |
| Q26739923 | Targeting DNA Replication Stress for Cancer Therapy |
| Q40351043 | The selective inhibition of protein phosphatase-1 results in mitotic catastrophe and impaired tumor growth |
| Q41709133 | p53-independent p21 induction by MELK inhibition |
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