MELK kinase holds promise as a new radiosensitizing target and biomarker in triple-negative breast cancer

scientific article published on October 2016

MELK kinase holds promise as a new radiosensitizing target and biomarker in triple-negative breast cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.21037/JTD.2016.10.40
P932PMC publication ID5107521
P698PubMed publication ID27867630

P2093author name stringCarlos S Moreno
P2860cites workOTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic KinasesQ27313731
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.Q27824766
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implicationsQ27860709
Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibitionQ28537936
Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platformsQ33244907
MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.Q33762222
EZH2 protects glioma stem cells from radiation-induced cell death in a MELK/FOXM1-dependent mannerQ35075212
Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cellsQ37099799
Identification of novel kinase targets for the treatment of estrogen receptor-negative breast cancerQ37389790
The Evolving Landscape of HER2 Targeting in Breast CancerQ38552750
Race and triple negative threats to breast cancer survival: a population-based study in Atlanta, GA.Q39837918
A retrospective study of breast cancer subtypes: the risk of relapse and the relations with treatmentsQ42492946
Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatmentQ46641346
Maternal Embryonic Leucine Zipper Kinase (MELK) as a Novel Mediator and Biomarker of Radioresistance in Human Breast Cancer.Q55008828
P433issue10
P921main subjectbiomarkerQ864574
P304page(s)E1367-E1368
P577publication date2016-10-01
P1433published inJournal of thoracic diseaseQ26841814
P1476titleMELK kinase holds promise as a new radiosensitizing target and biomarker in triple-negative breast cancer
P478volume8

Reverse relations

cites work (P2860)
Q91586857Bioinformatic analysis identifies potentially key differentially expressed genes in oncogenesis and progression of clear cell renal cell carcinoma
Q92465189Mutant P53 induces MELK expression by release of wild-type P53-dependent suppression of FOXM1
Q94475380Narrowing the focus: Therapeutic cell surface targets for refractory triple-negative breast cancer
Q46233466The microRNAs miR-200b-3p and miR-429-5p target the LIMK1/CFL1 pathway to inhibit growth and motility of breast cancer cells.
Q47801891Whole-exome analysis of a Li-Fraumeni family trio with a novel TP53 PRD mutation and anticipation profile.

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