scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | Appella E | |
Anderson CW | |||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | genotoxicity | Q1009245 |
P304 | page(s) | 2764-72 | |
P577 | publication date | 2001-05-01 | |
P1433 | published in | FEBS Journal | Q1388041 |
P1476 | title | Post-translational modifications and activation of p53 by genotoxic stresses | |
P478 | volume | 268 |
Q24306380 | 14-3-3gamma binds to MDMX that is phosphorylated by UV-activated Chk1, resulting in p53 activation |
Q51726272 | 17β-Estradiol Protects Skeletal Myoblasts From Apoptosis Through p53, Bcl-2, and FoxO Families. |
Q33739906 | 5-Lipoxygenase regulates senescence-like growth arrest by promoting ROS-dependent p53 activation |
Q47137519 | A model of the onset of the senescence associated secretory phenotype after DNA damage induced senescence |
Q28202389 | A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins |
Q37834073 | A novel oncoprotein Pirh2: rising from the shadow of MDM2. |
Q51116828 | A plausible model for bimodal p53 switch in DNA damage response. |
Q42563644 | A pool of peptides extracted from wheat bud chromatin inhibits tumor cell growth by causing defective DNA synthesis |
Q34572898 | A role for p53 in the frequency and mechanism of mutation |
Q39991228 | A role of HAUSP in tumor suppression in a human colon carcinoma xenograft model |
Q35158037 | A spatiotemporal characterization of the effect of p53 phosphorylation on its interaction with MDM2. |
Q39246185 | A systematic screen reveals MicroRNA clusters that significantly regulate four major signaling pathways |
Q34385189 | ABRO1 suppresses tumourigenesis and regulates the DNA damage response by stabilizing p53. |
Q36282831 | AMP-activated Protein Kinase (AMPK) Control of mTORC1 Is p53- and TSC2-independent in Pemetrexed-treated Carcinoma Cells |
Q34753639 | ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage |
Q53169706 | ATM mediates interdependent activation of p53 and ERK through formation of a ternary complex with p-p53 and p-ERK in response to DNA damage. |
Q40747424 | ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation |
Q39961624 | ATR-dependent activation of p38 MAP kinase is responsible for apoptotic cell death in cells depleted of Cdc7. |
Q79423580 | Ablation of a peptidyl prolyl isomerase Pin1 from p53-null mice accelerated thymic hyperplasia by increasing the level of the intracellular form of Notch1 |
Q35403658 | Absence of Wip1 partially rescues Atm deficiency phenotypes in mice |
Q37543781 | Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation |
Q43970143 | Accumulation of an inactive form of p53 protein in cells treated with TNF alpha |
Q37190330 | Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer |
Q35071254 | Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage |
Q34520098 | Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1). |
Q28215308 | Activation of p53 by protein inhibitor of activated Stat1 (PIAS1) |
Q33562197 | Activation of p53 promotes renal injury in acute aristolochic acid nephropathy |
Q34605518 | Activation of the p53 tumor suppressor protein |
Q44746842 | Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer |
Q39123275 | Alarmins: Feel the Stress. |
Q36560030 | Altered binding site selection of p53 transcription cassettes by hepatitis B virus X protein |
Q41679630 | Altered global gene expression profiles in human gastrointestinal epithelial Caco2 cells exposed to nanosilver |
Q28218469 | Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity |
Q38296791 | An ATM- and Rad3-related (ATR) signaling pathway and a phosphorylation-acetylation cascade are involved in activation of p53/p21Waf1/Cip1 in response to 5-aza-2'-deoxycytidine treatment |
Q34326755 | An aqueous extract of Fagonia cretica induces DNA damage, cell cycle arrest and apoptosis in breast cancer cells via FOXO3a and p53 expression. |
Q40175886 | An essential role of human Ada3 in p53 acetylation |
Q42803501 | Analysis of cellular response to isocyanate using N-succinimidyl N-methylcarbamate exposure in cultured mammalian cells. |
Q40003995 | Anti-apoptotic effect of Mao-B inhibitor PF9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine] is mediated by p53 pathway inhibition in MPP+-treated SH-SY5Y human dopaminergic cells |
Q30433930 | Anxiety and the aging brain: stressed out over p53? |
Q37011615 | Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/Chk2. |
Q91650984 | Aristolochic Acid-Induced Genotoxicity and Toxicogenomic Changes in Rodents |
Q51775699 | Association between a functional single nucleotide polymorphism in the MDM2 gene and sporadic endometrial cancer risk. |
Q24519076 | Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors |
Q40146768 | Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents |
Q39922066 | Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine |
Q34410831 | Attenuation of BPDE-induced p53 accumulation by TPA is associated with a decrease in stability and phosphorylation of p53 and downregulation of NFkappaB activation: role of p38 MAP kinase |
Q39241369 | Attractor landscape analysis reveals feedback loops in the p53 network that control the cellular response to DNA damage |
Q39430447 | Aurora A mediates cross-talk between N- and C-terminal post-translational modifications of p53 |
Q53022205 | BIRC6 promotes hepatocellular carcinogenesis: interaction of BIRC6 with p53 facilitating p53 degradation. |
Q34775325 | BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination |
Q73905084 | BRCA1: a scaffold for p53 response? |
Q35082715 | Balance of Yin and Yang: ubiquitylation-mediated regulation of p53 and c-Myc |
Q38282236 | Battle against cancer: an everlasting saga of p53. |
Q30492381 | Bax shuttling after neonatal hypoxia-ischemia: hyperoxia effects |
Q38267182 | Biomarkers to assess the efficiency of treatment with platinum-based drugs: what can metallomics add? |
Q41051383 | Breast cancer risk in relation to TP53 codon 72 and CDH1 gene polymorphisms in the Bangladeshi women |
Q37683765 | C/EBPalpha is a DNA damage-inducible p53-regulated mediator of the G1 checkpoint in keratinocytes |
Q57461774 | C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event |
Q39498948 | Cancer cells activate p53 in response to 10-formyltetrahydrofolate dehydrogenase expression |
Q36697632 | Cell Differentiation and Checkpoint |
Q27011729 | Cell cycle progression by the repression of primary cilia formation in proliferating cells |
Q28201863 | Cell cycle regulation and p53 activation by protein phosphatase 2C alpha |
Q41842385 | Cell cycle-dependent nuclear retention of p53 by E2F1 requires phosphorylation of p53 at Ser315. |
Q38351593 | Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses |
Q99575524 | Central and Peripheral Actions of Melatonin on Reproduction in Seasonal and Continuous Breeding Mammals |
Q38355401 | Central and carboxy‐terminal regions of human p53 protein are essential for interaction and complex formation with PARP‐1 |
Q53253493 | Changes in SIRT1 expression and its downstream pathways in age-related cataract in humans. |
Q24299815 | Characterisation of the interface between nucleophosmin (NPM) and p53: potential role in p53 stabilisation |
Q44938220 | Characterization of Tetrahymena histone H2B variants and posttranslational populations by electron capture dissociation (ECD) Fourier transform ion cyclotron mass spectrometry (FT-ICR MS). |
Q40408481 | Checkpoint kinase 1 regulates diallyl trisulfide-induced mitotic arrest in human prostate cancer cells |
Q42089922 | Cheliensisin A inhibits EGF-induced cell transformation with stabilization of p53 protein via a hydrogen peroxide/Chk1-dependent axis |
Q34149479 | Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription |
Q24607826 | Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells |
Q29615385 | Cisplatin: mode of cytotoxic action and molecular basis of resistance |
Q47756444 | Classification of in vitro genotoxicants using a novel multiplexed biomarker assay compared to the flow cytometric micronucleus test |
Q33250663 | Cloning and characterization of the human gene DERP6, which activates transcriptional activities of p53. |
Q47427915 | Co-expressions of casein kinase 2 (CK2) subunits restore the down-regulation of tubulin levels and disruption of microtubule structures caused by PrP mutants |
Q41472341 | Combination of proteasomal inhibitors lactacystin and MG132 induced synergistic apoptosis in prostate cancer cells |
Q30382652 | Comparing models of evolution for ordered and disordered proteins. |
Q38787249 | Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination |
Q38359899 | Constitutive DNase I hypersensitivity of p53-regulated promoters |
Q28236097 | Control of the G2/M transition |
Q40127941 | Cooperation between JNK1 and JNK2 in activation of p53 apoptotic pathway |
Q34241074 | Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo |
Q24655602 | Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2 |
Q42371971 | Coumarin-chalcone hybrid instigates DNA damage by minor groove binding and stabilizes p53 through post translational modifications. |
Q34614596 | Crippling p53 activities via knock-in mutations in mouse models |
Q38984847 | Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters |
Q46985048 | Crosstalk between site-specific modifications on p53 and histone H3. |
Q24311663 | Crosstalk between sumoylation and acetylation regulates p53-dependent chromatin transcription and DNA binding |
Q40114433 | Cyclosporine A induces senescence in renal tubular epithelial cells |
Q34040102 | Cys-141 glutathionylation of human p53: Studies using specific polyclonal antibodies in cancer samples and cell lines |
Q39777007 | Cytoplasmic p53 and activated Bax regulate p53-dependent, transcription-independent neural precursor cell apoptosis. |
Q40203768 | DNA binding and selective gene induction by different forms of the p53 protein |
Q36325437 | DNA damage checkpoints in mammals |
Q42807917 | DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines |
Q38212164 | DNA damage response in plants: conserved and variable response compared to animals |
Q24338364 | DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation |
Q40696914 | DNA damage-induced translocation of the Werner helicase is regulated by acetylation |
Q53598752 | DNA modification with cisplatin affects sequence-specific DNA binding of p53 and p73 proteins in a target site-dependent manner. |
Q34353609 | DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation. |
Q26775866 | DNA repair and aging: the impact of the p53 family |
Q33759285 | DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion |
Q42435054 | DNA-dependent acetylation of p53 by the transcription coactivator p300. |
Q24339462 | DRAGO (KIAA0247), a new DNA damage-responsive, p53-inducible gene that cooperates with p53 as oncosuppressor. [Corrected] |
Q40775865 | Decision Making by p53: Life versus Death |
Q34089507 | Deconstructing PML-induced premature senescence |
Q44867450 | Decreased survival of C/EBP beta-deficient keratinocytes is due to aberrant regulation of p53 levels and function |
Q46772713 | Defect in serine 46 phosphorylation of p53 contributes to acquisition of p53 resistance in oral squamous cell carcinoma cells. |
Q37524264 | Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23. |
Q36516076 | Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3beta |
Q40626844 | Defective p53 post-translational modification required for wild type p53 inactivation in malignant epithelial cells with mdm2 gene amplification |
Q50316561 | Delineating Crosstalk Mechanisms of the Ubiquitin Proteasome System That Regulate Apoptosis |
Q28578074 | Delta(9)-tetrahydrocannabinol regulates the p53 post-translational modifiers Murine double minute 2 and the Small Ubiquitin MOdifier protein in the rat brain |
Q29619786 | Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice |
Q37351323 | Diabetes and apoptosis: neural crest cells and neural tube. |
Q28567929 | Diabetes-induced oxidative DNA damage alters p53-p21CIP1/Waf1 signaling in the rat testis |
Q40439624 | Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination |
Q34459620 | Differential effects of 5-aminolaevulinic acid photodynamic therapy and psoralen + ultraviolet A therapy on p53 phosphorylation in normal human skin in vivo. |
Q35290386 | Differential modulatory effects of GSK-3β and HDM2 on sorafenib-induced AIF nuclear translocation (programmed necrosis) in melanoma |
Q34443272 | Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence. |
Q40540255 | Differentiation-induced radioresistance in muscle cells |
Q43690470 | Direct demonstration of rapid degradation of nuclear sterol regulatory element-binding proteins by the ubiquitin-proteasome pathway |
Q42724753 | Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters. |
Q37343700 | Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. |
Q44830479 | Discrete signaling pathways participate in RB-dependent responses to chemotherapeutic agents |
Q35078774 | Disrupting TP53 in mouse models of human cancers |
Q39310490 | Disruption of the p53-p21 pathway inhibits efficiency of the lytic-replication cycle of herpes simplex virus type 2 (HSV-2). |
Q39848157 | Dissection of the sequence-specific DNA binding and exonuclease activities reveals a superactive yet apoptotically impaired mutant p53 protein |
Q36908396 | Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation. |
Q36117542 | Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate. |
Q42035568 | Does control of mutant p53 by Mdm2 complicate cancer therapy? |
Q34736706 | Does p53 affect organismal aging? |
Q38150426 | Doxorubicin-induced death in tumour cells and cardiomyocytes: is autophagy the key to improving future clinical outcomes? |
Q34181652 | Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells |
Q39109039 | E2F1 activates p53 transcription through its distal site and participates in apoptosis induction in HPV-positive cells. |
Q34284001 | E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis |
Q34869507 | EDD inhibits ATM-mediated phosphorylation of p53. |
Q40150740 | Effect of distinct anticancer drugs on the phosphorylation of p53 protein at serine 46 in human MCF-7 breast cancer cells |
Q36377767 | Effect of maternal Tp53 gene G412C polymorphism on neural tube defects: A study from North India |
Q37729128 | Effects of NS1 variants of H5N1 influenza virus on interferon induction, TNFalpha response and p53 activity |
Q40339093 | Effects of folate deficiency on gene expression in the apoptosis and cancer pathways in colon cancer cells |
Q41863996 | Effects of gamma irradiation on cell cycle, apoptosis and telomerase activity in p53 wild-type and deficient HCT116 colon cancer cell lines |
Q64387009 | Effects of l-ascorbic acid on two cycles of cisplatin-induced DNA double-strand breaks and phosphorylation of p53 in the liver |
Q38590435 | Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes |
Q34097322 | Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3beta |
Q24306430 | Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta |
Q79610624 | Energy-dependent nucleolar localization of p53 in vitro requires two discrete regions within the p53 carboxyl terminus |
Q41850633 | Etoposide induces cell death via mitochondrial-dependent actions of p53. |
Q34545941 | Evidence that the human cytomegalovirus IE2-86 protein binds mdm2 and facilitates mdm2 degradation |
Q40290190 | Excess HDM2 impacts cell cycle and apoptosis and has a selective effect on p53-dependent transcription. |
Q37277722 | Expression and clinical significance of the nin one binding protein and p38 MAPK in prostate carcinoma |
Q28266839 | Expression of MCM10 and TopBP1 is regulated by cell proliferation and UV irradiation via the E2F transcription factor |
Q46965910 | Expression of RAD51, BRCA1 and P53 does not correlate with cellular radiosensitivity of normal human fibroblasts |
Q47336389 | Expression of SIRT1 and P53 in Rat Lens Epithelial cells in Experimentally Induced DM. |
Q54770033 | Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development. |
Q44887454 | Expression, interaction, and proteolysis of death-associated protein kinase and p53 within vulnerable and resistant hippocampal subfields following seizures |
Q58080272 | Extensive Characterization of Heavily Modified Histone Tails by 193 nm Ultraviolet Photodissociation Mass Spectrometry via a Middle–Down Strategy |
Q36659141 | FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage |
Q35861153 | FUSE Binding Protein 1 Facilitates Persistent Hepatitis C Virus Replication in Hepatoma Cells by Regulating Tumor Suppressor p53. |
Q35098597 | Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity |
Q39340920 | Fludarabine nucleoside induces accumulations of p53, p63 and p73 in the nuclei of human B-lymphoid cell lines, with cytosolic and mitochondrial increases in p53. |
Q29248201 | Functional activation of mutant p53V172F by platinum analogs in cisplatin-resistant human tumor cells is dependent on serine-20 phosphorylation |
Q33863075 | Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity |
Q41832274 | Functional census of mutation sequence spaces: the example of p53 cancer rescue mutants. |
Q39080969 | Functions of the Tumor Suppressors p53 and Rb in Actin Cytoskeleton Remodeling |
Q36661575 | Gene activation by bioactive glasses |
Q23912208 | Gene expression profile of human lung epithelial cells chronically exposed to single-walled carbon nanotubes |
Q82489428 | Gene expression profiles in mouse lung tissue after administration of two cationic polymers used for nonviral gene delivery |
Q42347022 | Gene expression profiling of human blastocysts from in vivo and 'rescue IVM' with or without melatonin treatment |
Q34417108 | Genotoxic and non-genotoxic pathways of p53 induction |
Q47706011 | Genotoxic effects of food contact recycled paperboard extracts on two human hepatic cell lines |
Q34320186 | Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation |
Q38867373 | Gradual reduction in rRNA transcription triggers p53 acetylation and apoptosis via MYBBP1A. |
Q40421589 | HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage |
Q33292477 | HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations. |
Q24338503 | HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function |
Q80603062 | HIPK2-induced p53Ser46 phosphorylation activates the KILLER/DR5-mediated caspase-8 extrinsic apoptotic pathway |
Q24301527 | HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53 |
Q89634774 | Harnessing the vulnerabilities of p53 mutants in lung cancer - Focusing on the proteasome: a new trick for an old foe? |
Q43047407 | Hepatitis C virus core protein expression leads to biphasic regulation of the p21 cdk inhibitor and modulation of hepatocyte cell cycle |
Q39641751 | High glucose promotes nascent nephron apoptosis via NF-kappaB and p53 pathways |
Q26775761 | Histone deacetylase inhibitors in castration-resistant prostate cancer: molecular mechanism of action and recent clinical trials |
Q28082123 | Histone methylation modifiers in cellular signaling pathways |
Q40598361 | Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis |
Q37107268 | Homeostatic functions of the p53 tumor suppressor: regulation of energy metabolism and antioxidant defense |
Q36879036 | How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression? |
Q35700328 | How the nucleolar sequestration of p53 protein or its interplayers contributes to its (re)-activation |
Q24297146 | Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence |
Q28386709 | Human bronchial epithelial BEAS-2B cells, an appropriate in vitro model to study heavy metals induced carcinogenesis |
Q45729740 | Human immunodeficiency virus type-1 Tat/co-activator acetyltransferase interactions inhibit p53Lys-320 acetylation and p53-responsive transcription |
Q39904691 | Human inhibitor of growth 1 inhibits hepatoma cell growth and influences p53 stability in a variant-dependent manner |
Q40890409 | Human papillomavirus oncoprotein E7 targets the promyelocytic leukemia protein and circumvents cellular senescence via the Rb and p53 tumor suppressor pathways |
Q47784931 | Human papillomavirus type 77 E6 protein selectively inhibits p53-dependent transcription of proapoptotic genes following UV-B irradiation. |
Q27004438 | Hydrogen peroxide sensing, signaling and regulation of transcription factors |
Q38914905 | Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells |
Q40155261 | Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma |
Q38310551 | Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis |
Q21245725 | Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity |
Q37137685 | Hypoxia ischemia-mediated cell death in neonatal rat brain |
Q24529998 | ING2 regulates the onset of replicative senescence by induction of p300-dependent p53 acetylation |
Q37212448 | Identification of new p53 acetylation sites in COS-1 cells |
Q91980040 | Image analysis of mechanistic protein biomarkers for the characterization of genotoxicants: aneugens, clastogens and ROS inducers |
Q30460515 | Immunohistochemical detection of P53 and Mdm2 in vitiligo |
Q37258978 | Impairment of p53 acetylation, stability and function by an oncogenic transcription factor |
Q34227874 | Increased DNA methyltransferase 3b (Dnmt3b)-mediated CpG island methylation stimulated by oxidative stress inhibits expression of a gene required for neural tube and neural crest development in diabetic pregnancy. |
Q40747033 | Increased K+ efflux and apoptosis induced by the potassium channel modulatory protein KChAP/PIAS3beta in prostate cancer cells |
Q46976925 | Increased glomerular cell (podocyte) apoptosis in rats with streptozotocin-induced diabetes mellitus: role in the development of diabetic glomerular disease. |
Q37527427 | Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389. |
Q34344606 | Induction and bypass of p53 during productive infection by polyomavirus |
Q37014644 | Induction of PPM1D following DNA-damaging treatments through a conserved p53 response element coincides with a shift in the use of transcription initiation sites |
Q40639210 | Induction of p53-dependent activation of the human proliferating cell nuclear antigen gene in chromatin by ionizing radiation. |
Q34324710 | Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells |
Q40340028 | Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage |
Q36964274 | Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage |
Q33781782 | Inhibition of cell division by the human cytomegalovirus IE86 protein: role of the p53 pathway or cyclin-dependent kinase 1/cyclin B1. |
Q34434681 | Inhibition of the ATM/p53 signal transduction pathway by Kaposi's sarcoma-associated herpesvirus interferon regulatory factor 1. |
Q90146998 | Inhibitory effect of Korean Red Ginseng extract on DNA damage response and apoptosis in Helicobacter pylori-infected gastric epithelial cells |
Q48185356 | Inhibitory effects of different substituted transition metal-based krebs-type sandwich structures on human hepatocellular carcinoma cells. |
Q38177769 | Insights into wild-type and mutant p53 functions provided by genetically engineered mice |
Q21129288 | Interactomic and pharmacological insights on human sirt-1 |
Q24310030 | Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53 |
Q37456901 | Intracellular regulation of matrix metalloproteinase-2 activity: new strategies in treatment and protection of heart subjected to oxidative stress |
Q37932415 | Intrinsically disordered regions as affinity tuners in protein-DNA interactions |
Q43205198 | Isoform specific phosphorylation of p53 by protein kinase CK1. |
Q54190030 | JHDM1B expression regulates ribosome biogenesis and cancer cell growth in a p53 dependent manner. |
Q27320018 | JNK Inhibition Inhibits Lateral Line Neuromast Hair Cell Development |
Q44480063 | Jun N-terminal kinase activation and upregulation of p53 and p21(WAF1/CIP1) in selenite-induced apoptosis of regenerating liver |
Q34409029 | KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes |
Q33894543 | Ku86 is essential in human somatic cells |
Q39386130 | Lack of p53 induction in fish cells by model chemotherapeutics |
Q27009209 | Lessons learned from next-generation sequencing in head and neck cancer |
Q40570035 | Limited role of N-terminal phosphoserine residues in the activation of transcription by p53. |
Q41488339 | Live-cell p53 single-molecule binding is modulated by C-terminal acetylation and correlates with transcriptional activity. |
Q28205515 | Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53 |
Q62448159 | Long-range regulation of p53 DNA binding by its intrinsically disordered N-terminal transactivation domain |
Q35002156 | Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a |
Q28477245 | Loss of p53 Ser18 and Atm results in embryonic lethality without cooperation in tumorigenesis |
Q33290438 | Loss of robustness and addiction to IGF1 during early keratinocyte transformation by human Papilloma virus 16 |
Q41701656 | Low dose arsenite confers resistance to UV induced apoptosis via p53-MDM2 pathway in ketatinocytes |
Q38769335 | Lysines in the tetramerization domain of p53 selectively modulate G1 arrest |
Q40323831 | MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation |
Q24537700 | MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation |
Q24650130 | Mapping the interactions of the p53 transactivation domain with the KIX domain of CBP |
Q37099799 | Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells |
Q38059700 | Mdm2 and MdmX as Regulators of Gene Expression |
Q35857003 | Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest |
Q35572466 | Mdm2: A regulator of cell growth and death |
Q42141601 | Mechanisms of Cisplatin-Induced Apoptosis and of Cisplatin Sensitivity: Potential of BIN1 to Act as a Potent Predictor of Cisplatin Sensitivity in Gastric Cancer Treatment |
Q40954179 | Mechanistic clues to the protective effect of chrysin against doxorubicin-induced cardiomyopathy: Plausible roles of p53, MAPK and AKT pathways |
Q35853626 | Mediterranean diet supplemented with coenzyme Q10 induces postprandial changes in p53 in response to oxidative DNA damage in elderly subjects. |
Q24307834 | Metabolism, cytoskeleton and cellular signalling in the grip of protein Nepsilon - and O-acetylation |
Q40103473 | Methylation-acetylation interplay activates p53 in response to DNA damage |
Q30374671 | Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer. |
Q52624676 | Mitochondrial Fission Is Required for Angiotensin II-Induced Cardiomyocyte Apoptosis Mediated by a Sirt1-p53 Signaling Pathway. |
Q33249208 | Mode of interaction between butyroyloxymethyl-diethyl phosphate (AN-7) and doxorubicin in MCF-7 and resistant MCF-7/Dx cell lines |
Q34082945 | Modeling the basal dynamics of p53 system |
Q42484105 | Modeling the heterogeneity of p53 dynamics in DNA damage response |
Q33471807 | Modeling the role of p53 pulses in DNA damage- induced cell death decision. |
Q29615657 | Modes of p53 regulation |
Q38337938 | Modification of serine 392 is a critical event in the regulation of p53 nuclear export and stability |
Q45302322 | Modifications of p53 and the DNA damage response in cells expressing mutant form of the protein huntingtin |
Q83235743 | Modulation of p53 by mitogen-activated protein kinase pathways and protein kinase C delta during avian reovirus S1133-induced apoptosis |
Q40532008 | Modulation of p53 cellular function and cell death by African swine fever virus |
Q24337822 | Modulation of p53 function by SET8-mediated methylation at lysine 382 |
Q37926477 | Molecular mechanisms of cisplatin resistance |
Q24295012 | Monoubiquitylation promotes mitochondrial p53 translocation |
Q33752174 | Mouse models of p53 functions |
Q41890892 | Multiple stress signals activate mutant p53 in vivo |
Q35018012 | Multisite phosphorylation provides sophisticated regulation of transcription factors |
Q36033101 | Murine protein serine-threonine kinase 38 activates p53 function through Ser15 phosphorylation |
Q34277066 | Mutation of mouse p53 Ser23 and the response to DNA damage |
Q53623512 | Mutational analysis of the p53 core domain L1 loop. |
Q24337056 | NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequence-dependent manner |
Q45171395 | Nedd4-2 phosphorylation induces serum and glucocorticoid-regulated kinase (SGK) ubiquitination and degradation |
Q47881235 | Negative regulation of Chk2 expression by p53 is dependent on the CCAAT-binding transcription factor NF-Y. |
Q24303893 | Negative regulation of p53 functions by Daxx and the involvement of MDM2 |
Q34758670 | New insights into p53 activation |
Q44893903 | Nitric oxide-induced cell death of cerebrocortical murine astrocytes is mediated through p53- and Bax-dependent pathways |
Q33361623 | Noncanonical DNA motifs as transactivation targets by wild type and mutant p53 |
Q51759892 | Notch signaling and neuronal death in stroke. |
Q28262425 | Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy? |
Q47918094 | Nuclear localization of Y-box factor YB1 requires wild-type p53 |
Q36190104 | Nucleocytoplasmic Translocation of UBXN2A Is Required for Apoptosis during DNA Damage Stresses in Colon Cancer Cells. |
Q38107795 | Nucleolar control of p53: a cellular Achilles' heel and a target for cancer therapy. |
Q37833502 | Nucleophosmin and its complex network: a possible therapeutic target in hematological diseases. |
Q37424634 | Nucleophosmin sets a threshold for p53 response to UV radiation |
Q38656647 | Nutlin-3, A P53-Mdm2 Antagonist For Nasopharyngeal Carcinoma Treatment |
Q35785876 | Of flies and men; p53, a tumour suppressor |
Q33406279 | Oscillations of the p53-Akt network: implications on cell survival and death |
Q38045766 | Overexpression of p53 protein in human tumors |
Q35250855 | P53 and p73 differ in their ability to inhibit glucocorticoid receptor (GR) transcriptional activity |
Q28513393 | PACT is a negative regulator of p53 and essential for cell growth and embryonic development |
Q35006415 | PERP expression stabilizes active p53 via modulation of p53-MDM2 interaction in uveal melanoma cells. |
Q36358632 | PI3K/AKT inhibition induces caspase-dependent apoptosis in HTLV-1-transformed cells |
Q28080023 | PXR variants: the impact on drug metabolism and therapeutic responses |
Q44827793 | Pathway analysis using random forests classification and regression |
Q37212228 | Perspectives for cancer prevention with natural compounds |
Q34198570 | Phosphatases in the cellular response to DNA damage. |
Q33197915 | Phosphatidyl inositol 3-kinase-like serine/threonine protein kinases (PIKKs) are required for DNA damage-induced phosphorylation of the 32 kDa subunit of replication protein A at threonine 21. |
Q24701734 | Phosphorylation of Single Stranded RNA Virus Proteins and Potential for Novel Therapeutic Strategies |
Q40506599 | Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis |
Q33693493 | Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis |
Q24685095 | Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1 |
Q24322729 | Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression |
Q44513266 | Phosphorylation site interdependence of human p53 post-translational modifications in response to stress |
Q39097149 | Phosphorylation: Implications in Cancer |
Q28609772 | Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation |
Q24338733 | Polo-like kinase 1 regulates mitotic arrest after UV irradiation through dephosphorylation of p53 and inducing p53 degradation |
Q36251670 | Poly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cells |
Q35450753 | Poly(ADP-ribosyl)ation of p53 contributes to TPEN-induced neuronal apoptosis |
Q39764452 | Porcine circovirus type 2 ORF3 protein competes with p53 in binding to Pirh2 and mediates the deregulation of p53 homeostasis |
Q39669697 | Post-translational Modification of p53 by Ubiquitin |
Q35930703 | Post-translational modification of p53 in tumorigenesis |
Q34173442 | Posttranscriptional and posttranslational regulation of C/EBP delta in G0 growth-arrested mammary epithelial cells |
Q33899450 | Posttranslational modification of p53: cooperative integrators of function |
Q36527456 | Posttranslational phosphorylation of mutant p53 protein in tumor development |
Q36288249 | Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma |
Q40154434 | Prevention of p53 degradation in human MCF-7 cells by proteasome inhibitors does not mimic the action of roscovitine |
Q36082116 | Processive phosphorylation: mechanism and biological importance |
Q34831541 | Programmed cell death in amyotrophic lateral sclerosis |
Q48193766 | Protective effect of metoclopramide against organophosphate-induced apoptosis in the murine skin fibroblast L929. |
Q37800060 | Protein acetylation within the cellular response to radiation. |
Q36379368 | Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML. |
Q28749465 | Proximal events in 7,12-dimethylbenz[a]anthracene-induced, stromal cell-dependent bone marrow B cell apoptosis: stromal cell-B cell communication and apoptosis signaling |
Q35927931 | Quantitative analyses reveal the importance of regulated Hdmx degradation for p53 activation |
Q36685003 | Quantitative proteomics analysis of the effects of ionizing radiation in wild type and p53 K317R knock-in mouse thymocytes |
Q44374509 | Questioning the role of checkpoint kinase 2 in the p53 DNA damage response |
Q39597077 | RNA content in the nucleolus alters p53 acetylation via MYBBP1A. |
Q39952719 | Radiobiologic response of medulloblastoma cell lines: involvement of beta-catenin? |
Q28537881 | Reactive oxygen species mediate Epstein-Barr virus reactivation by N-methyl-N'-nitro-N-nitrosoguanidine |
Q37285111 | Reactive oxygen species-independent oxidation of thioredoxin in hypoxia: inactivation of ribonucleotide reductase and redox-mediated checkpoint control |
Q34794627 | Receptor-mediated hepatocarcinogenesis: role of hepatocyte proliferation and apoptosis |
Q38355560 | Recognition of DNA modified by antitumor cisplatin by “latent” and “active” protein p53 |
Q28214575 | Recombinational DNA repair and human disease |
Q37861632 | Redox modulation of p53: mechanisms and functional significance |
Q41619942 | Regulation of Eaf2 in mouse lens cells apoptosis induced by ultraviolet radiation |
Q42506403 | Regulation of P53 stability in p53 mutated human and mouse hepatoma cells |
Q38287796 | Regulation of apoptosis by p53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes |
Q28210189 | Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2 |
Q24311514 | Regulation of p53 activity through lysine methylation |
Q40346478 | Regulation of p53 by activated protein kinase C-delta during nitric oxide-induced dopaminergic cell death |
Q35009505 | Regulation of p53 by jagged1 contributes to angiotensin II-induced impairment of myocardial angiogenesis |
Q35149921 | Regulation of p53 function by lysine methylation |
Q74285071 | Regulation of p53 sequence-specific DNA-binding by covalent poly(ADP-ribosyl)ation |
Q35047240 | Regulation of tumor suppressors by nuclear-cytoplasmic shuttling |
Q28586399 | Regulation of ubiquitin ligase dynamics by the nucleolus |
Q38739516 | Renal Protective Effects of 17β-Estradiol on Mice with Acute Aristolochic Acid Nephropathy |
Q35116649 | Renewing the debate over the p53 apoptotic response |
Q35005937 | Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis |
Q27006998 | Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53 |
Q44635839 | Resistance to UV‐induced apoptosis in human keratinocytes during accelerated senescence is associated with functional inactivation of p53 |
Q43101429 | Response to DNA damage: why do we need to focus on protein phosphatases? |
Q39032730 | Restoration of p53/miR-34a regulatory axis decreases survival advantage and ensures Bax-dependent apoptosis of non-small cell lung carcinoma cells |
Q38333341 | Restoration of tumor suppressor p53 by differentially regulating pro- and anti-p53 networks in HPV-18-infected cervical cancer cells. |
Q37831934 | Resveratrol and apoptosis |
Q41816825 | Resveratrol inhibits β-amyloid-induced neuronal apoptosis via regulation of p53 acetylation in PC12 cells |
Q35075426 | Retracted: Residues 240-250 in the C-Terminus of the Pirh2 Protein Complement the Function of the RING Domain in Self-Ubiquitination of the Pirh2 Protein |
Q37000240 | Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling |
Q36863596 | Role of p38 and JNK MAPK signaling pathways and tumor suppressor p53 on induction of apoptosis in response to Ad-eIF5A1 in A549 lung cancer cells |
Q38883419 | Role of p53 isoforms and aggregations in cancer |
Q39687338 | Role of tumor suppressor p53 domains in selective binding to supercoiled DNA. |
Q37518662 | Rotational positioning of nucleosomes facilitates selective binding of p53 to response elements associated with cell cycle arrest |
Q38926772 | SIRT1 Protects Human Lens Epithelial Cells Against Oxidative Stress by Inhibiting p53-Dependent Apoptosis |
Q34341091 | SIRT1 and p53, effect on cancer, senescence and beyond |
Q40182201 | SMAR1-derived P44 peptide retains its tumor suppressor function through modulation of p53. |
Q48166923 | SO2 inhalation modulates the expression of apoptosis-related genes in rat hippocampus via its derivatives in vivo |
Q97516927 | SUMOylation in α-Synuclein Homeostasis and Pathology |
Q91931124 | Selection and characterization of FcεRI phospho-ITAM specific antibodies |
Q35206381 | Signaling to p53: ribosomal proteins find their way. |
Q28481334 | Simulating molecular mechanisms of the MDM2-mediated regulatory interactions: a conformational selection model of the MDM2 lid dynamics |
Q40251384 | Single-nucleotide polymorphisms in the p53 pathway |
Q24303857 | Sirtuin functions in health and disease |
Q37806669 | Small-Molecule Inhibitors of the p53-MDM2 Interaction |
Q40005223 | Stabilization of p53 is involved in quercetin-induced cell cycle arrest and apoptosis in HepG2 cells |
Q40630934 | Status of p53 phosphorylation and function in sensitive and resistant human cancer models exposed to platinum-based DNA damaging agents. |
Q52827047 | Stress-induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts. |
Q36185135 | Stress-mediated Sin3B activation leads to negative regulation of subset of p53 target genes. |
Q35569661 | Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-alpha3 binding |
Q92327944 | Stretching magnitude-dependent inactivation of AKT by ROS led to enhanced p53 mitochondrial translocation and myoblast apoptosis |
Q24653926 | Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation |
Q40373998 | Structural details on mdm2-p53 interaction |
Q27658473 | Structure of the Taz2 domain of p300: insights into ligand binding |
Q46289632 | Study of p53 expression and post-transcriptional modifications after GSM-900 radiofrequency exposure of human amniotic cells. |
Q37423898 | Suberoylanilide hydroxamic acid represses glioma stem-like cells. |
Q37612047 | Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression. |
Q24551106 | Supramolecular complex formation between Rad6 and proteins of the p53 pathway during DNA damage-induced response |
Q35967111 | Surf the post-translational modification network of p53 regulation |
Q24292042 | TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence |
Q50088140 | TP53 Haploinsufficiency Rescues Emergency Granulopoiesis in FANCC-/- Mice |
Q53809236 | TP53 overexpression in recurrent endometrial carcinoma. |
Q34568607 | TP53: a key gene in human cancer. |
Q90232350 | Targeting phosphorylated p53 to elicit tumor-reactive T helper responses against head and neck squamous cell carcinoma |
Q34011368 | Targeting protein inactivation through an oligomerization chain reaction |
Q37728628 | Targets and consequences of protein SUMOylation in neurons. |
Q51864239 | Telomere dysfunction and cell cycle checkpoints in hematopoietic stem cell aging. |
Q40700411 | Temperature-sensitive ovarian carcinoma cell line (OvBH-1). |
Q44374511 | The Chk2 tumor suppressor is not required for p53 responses in human cancer cells |
Q36149280 | The DNA binding and accumulation of p53 from breast cancer cell lines and the link with serine 15 phosphorylation |
Q34350684 | The Epstein-Barr virus immediate-early protein BZLF1 regulates p53 function through multiple mechanisms |
Q27664677 | The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression |
Q36430168 | The P53 pathway: what questions remain to be explored? |
Q47307122 | The Roles of P53 and its Family Proteins, P63 and P73, in the DNA Damage Stress Response in Organogenesis Stage Mouse Embryos. |
Q24297633 | The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop |
Q36497975 | The absence of Ser389 phosphorylation in p53 affects the basal gene expression level of many p53-dependent genes and alters the biphasic response to UV exposure in mouse embryonic fibroblasts. |
Q34519833 | The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes |
Q37687474 | The cell death machinery governed by the p53 tumor suppressor in response to DNA damage |
Q36443523 | The complexity of p53 stabilization and activation |
Q42806263 | The cytoprotective aminothiol WR1065 activates p53 through a non-genotoxic signaling pathway involving c-Jun N-terminal kinase. |
Q37859721 | The dual role of p53: DNA protection and antioxidant. |
Q26851138 | The expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2 |
Q34199692 | The impact of acetylation and deacetylation on the p53 pathway |
Q36649149 | The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss |
Q33343721 | The metastasis-associated protein S100A4 exists in several charged variants suggesting the presence of posttranslational modifications |
Q28201932 | The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity |
Q36661071 | The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cells |
Q92062954 | The multiple mechanisms that regulate p53 activity and cell fate |
Q37596345 | The nucleolar protein Myb-binding protein 1A (MYBBP1A) enhances p53 tetramerization and acetylation in response to nucleolar disruption |
Q35078417 | The p53 network in head and neck cancer |
Q34935933 | The p53 network in lung carcinogenesis. |
Q28206425 | The processing of Holliday junctions by BLM and WRN helicases is regulated by p53 |
Q24295229 | The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP |
Q44480812 | The promyelocytic leukemia protein protects p53 from Mdm2-mediated inhibition and degradation |
Q47135845 | The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation |
Q44418946 | The role of p53 deacetylation in p21Waf1 regulation by laminar flow |
Q24337220 | The subcellular localization of vaccinia-related kinase-2 (VRK2) isoforms determines their different effect on p53 stability in tumour cell lines |
Q24293463 | The transcriptional regulation role of BRD7 by binding to acetylated histone through bromodomain |
Q52651121 | Tip60: updates. |
Q30394774 | Towards understanding the crosstalk between protein post-translational modifications: Homo- and heterotypic PTM pair distances on protein surfaces are not random |
Q52940731 | Toxicogenomic responses of human liver HepG2 cells to silver nanoparticles. |
Q27679224 | Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code |
Q35127007 | Transcription factor p53 influences microglial activation phenotype |
Q38344277 | Transcription factors and cognate signalling cascades in the regulation of autophagy |
Q40251375 | Transcriptional regulation by p53 and p73. |
Q36436698 | Transcriptional regulation by p53: one protein, many possibilities |
Q36430154 | Translational research? Ribosome integrity and a new p53 tumor suppressor checkpoint |
Q24796110 | Treatment of terminal peritoneal carcinomatosis by a transducible p53-activating peptide |
Q37412688 | Tumor suppressive functions of p53 |
Q35162377 | Tumour suppressors--a fly's perspective |
Q33764044 | Two distinct motifs within the p53 transactivation domain bind to the Taz2 domain of p300 and are differentially affected by phosphorylation |
Q24296967 | USP10 regulates p53 localization and stability by deubiquitinating p53 |
Q33707419 | USP7/HAUSP Promotes the Sequence-Specific DNA Binding Activity of p53 |
Q40724097 | UVB-mediated activation of p38 mitogen-activated protein kinase enhances resistance of normal human keratinocytes to apoptosis by stabilizing cytoplasmic p53. |
Q53467454 | Ubiquitin over-expression promotes E6AP autodegradation and reactivation of the p53/MDM2 pathway in HeLa cells. |
Q35089377 | Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation |
Q28118867 | Uncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its Activation |
Q34322386 | Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link? |
Q33300777 | Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer |
Q43254285 | Use of pifithrin to inhibit p53-mediated signalling of TNF in dystrophic muscles of mdx mice. |
Q37748214 | Using mice to examine p53 functions in cancer, aging, and longevity |
Q37087404 | Versatile functions of p53 protein in multicellular organisms |
Q49700166 | Vitamin D receptor deficit induces activation of renin angiotensin system via SIRT1 modulation in podocytes |
Q34989369 | Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress |
Q39807046 | Wip1 confers G2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression. |
Q39523533 | XIAP-associated factor 1 (XAF1), a novel target of p53, enhances p53-mediated apoptosis via post-translational modification |
Q37484473 | YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress. |
Q53622636 | c-Abl phosphorylates Hdm2 at tyrosine 276 in response to DNA damage and regulates interaction with ARF. |
Q24338336 | hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes |
Q36560478 | hnRNP Q regulates translation of p53 in normal and stress conditions |
Q36064954 | miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis |
Q35648431 | p21Waf1/Cip1 and the prevention of oxidative stress |
Q35941622 | p38 MAP kinase's emerging role as a tumor suppressor |
Q33734522 | p53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation. |
Q35679117 | p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less Hepatotoxic Regioisomer Both In Vitro and In Vivo |
Q41811657 | p53 Loses grip on PIK3CA expression leading to enhanced cell survival during platinum resistance |
Q44607626 | p53 N-terminal Ser-15 approximately P and Ser-20 approximately P levels in squamous cell lung cancer after radio/chemotherapy. |
Q28079390 | p53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum Concept |
Q36088355 | p53 RNA interactions: new clues in an old mystery |
Q36777320 | p53 alterations in human cancer: more questions than answers. |
Q53561930 | p53 and Delta Np63 alpha differentially bind and regulate target genes involved in cell cycle arrest, DNA repair and apoptosis. |
Q44592743 | p53 and mitogen-activated protein kinase pathway protein profiles in fresh and frozen spermatozoa |
Q33569713 | p53 binding to nucleosomal DNA depends on the rotational positioning of DNA response element |
Q37376012 | p53 polymorphisms: cancer implications |
Q28210026 | p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex |
Q27302884 | p53 target gene SMAR1 is dysregulated in breast cancer: its role in cancer cell migration and invasion |
Q39061575 | p53 tumor suppressor protein stability and transcriptional activity are targeted by Kaposi's sarcoma-associated herpesvirus-encoded viral interferon regulatory factor 3. |
Q42362115 | p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance |
Q34515770 | p53, p63 and p73--solos, alliances and feuds among family members |
Q42098836 | p53-Dependent p21 mRNA elongation is impaired when DNA replication is stalled. |
Q44945710 | p53-dependent transcription can exhibit both on/off and graded response after genotoxic stress |
Q38247164 | p53-independent effects of Mdm2. |
Q36846083 | p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo |
Q24338379 | p53: 25 years after its discovery |
Q38333104 | p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2. |
Q38319824 | tumor suppressor p53 binds with high affinity to CTG.CAG trinucleotide repeats and induces topological alterations in mismatched duplexes |
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