scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1046314509 |
P356 | DOI | 10.1038/SJ.ONC.1205870 |
P3181 | OpenCitations bibliographic resource ID | 2295741 |
P698 | PubMed publication ID | 12400006 |
P5875 | ResearchGate publication ID | 11063683 |
P2093 | author name string | Bernard Ducommun | |
Véronique Baldin | |||
Noélie Davezac | |||
Jean-Pierre Tassan | |||
Joëlle Blot | |||
P2860 | cites work | Study of the cytolethal distending toxin-induced cell cycle arrest in HeLa cells: involvement of the CDC25 phosphatase | Q73896708 |
Cell cycle dependent subcellular distribution of Cdc25B subtypes | Q77811811 | ||
Specific interaction between 14-3-3 isoforms and the human CDC25B phosphatase | Q22253333 | ||
MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption | Q24313701 | ||
The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex | Q24314687 | ||
Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins | Q24314904 | ||
14-3-3 proteins associate with cdc25 phosphatases | Q24324041 | ||
Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2 | Q24338853 | ||
Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15 | Q24564843 | ||
Cdc25B and Cdc25C differ markedly in their properties as initiators of mitosis | Q24685826 | ||
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25 | Q28247761 | ||
Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216 | Q28247771 | ||
Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1 | Q28285538 | ||
par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed | Q28301842 | ||
Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site | Q28610026 | ||
Cyclin-dependent kinases: engines, clocks, and microprocessors | Q29614786 | ||
Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis | Q29618506 | ||
Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog | Q29618844 | ||
A targeted library of small-molecule, tyrosine, and dual-specificity phosphatase inhibitors derived from a rational core design and random side chain variation | Q32179961 | ||
Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis | Q33756990 | ||
A putative protein kinase gene (kin1+) is important for growth polarity in Schizosaccharomyces pombe. | Q33861197 | ||
Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import | Q33890764 | ||
Phosphorylation of human CDC25B phosphatase by CDK1-cyclin A triggers its proteasome-dependent degradation | Q34450218 | ||
Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25. | Q35203445 | ||
p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells. | Q37629320 | ||
Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition | Q40793182 | ||
Cdc25B activity is regulated by 14-3-3. | Q43683797 | ||
Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15. | Q46903641 | ||
Cell cycle regulation of pEg3, a new Xenopus protein kinase of the KIN1/PAR-1/MARK family | Q48871311 | ||
Regulation of CDC25B phosphatases subcellular localization | Q63681677 | ||
Hyperphosphorylation of the N-terminal domain of Cdc25 regulates activity toward cyclin B1/Cdc2 but not cyclin A/Cdk2 | Q73836216 | ||
P433 | issue | 50 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
protein serine/threonine kinase activity | Q14326094 | ||
Cell division cycle 25B | Q21109234 | ||
Maternal embryonic leucine zipper kinase | Q21173216 | ||
P304 | page(s) | 7630-41 | |
P577 | publication date | 2002-10-31 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation | |
P478 | volume | 21 |
Q28509021 | Asymmetric distribution of PAR proteins in the mouse embryo begins at the 8-cell stage during compaction |
Q36643905 | Caenorhabditis elegans PIG-1/MELK acts in a conserved PAR-4/LKB1 polarity pathway to promote asymmetric neuroblast divisions |
Q37233429 | Cell-cycle dependent localization of MELK and its new partner RACK1 in epithelial versus mesenchyme-like cells in Xenopus embryo |
Q24323019 | Cell-cycle-dependent cortical localization of pEg3 protein kinase in Xenopus and human cells |
Q92068313 | Cloning, tissue distribution, expression pattern, and function of porcine maternal embryonic leucine zipper kinase |
Q38703734 | Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with a focus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development. |
Q38577467 | Cortical localization of maternal embryonic leucine zipper kinase (MELK) implicated in cytokinesis in early xenopus embryos |
Q53387038 | Expression levels of NF-Y target genes changed by CDKN1B correlate with clinical prognosis in multiple cancers. |
Q21284186 | Identification of novel mitosis regulators through data mining with human centromere/kinetochore proteins as group queries |
Q50043890 | Identification of potential therapeutic targets in prostate cancer through a cross-species approach. |
Q92153843 | Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma |
Q89082194 | Inhibition of maternal embryonic leucine zipper kinase with OTSSP167 displays potent anti-leukemic effects in chronic lymphocytic leukemia |
Q28236635 | Inhibition of spliceosome assembly by the cell cycle-regulated protein kinase MELK and involvement of splicing factor NIPP1 |
Q47113243 | KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition. |
Q57188204 | Kin1 kinase localizes at the hyphal septum and is dephosphorylated by calcineurin but is dispensable for septation and virulence in the human pathogen Aspergillus fumigatus |
Q47105077 | MELK Promotes Melanoma Growth by Stimulating the NF-κB Pathway |
Q54977971 | MELK as a potential target to control cell proliferation in triple-negative breast cancer MDA-MB-231 cells. |
Q38715935 | MELK expression in ovarian cancer correlates with poor outcome and its inhibition by OTSSP167 abrogates proliferation and viability of ovarian cancer cells |
Q50994627 | MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells. |
Q33762222 | MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells. |
Q41705554 | MELK is not necessary for the proliferation of basal-like breast cancer cells |
Q92501934 | MELK promotes Endometrial carcinoma progression via activating mTOR signaling pathway |
Q38648606 | MELK: a potential novel therapeutic target for TNBC and other aggressive malignancies. |
Q37099799 | Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells |
Q28591125 | Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation |
Q27022633 | Maternal embryonic leucine zipper kinase (MELK): a novel regulator in cell cycle control, embryonic development, and cancer |
Q33960305 | Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway |
Q91329661 | Maternal embryonic leucine zipper kinase is a novel target for diffuse large B cell lymphoma and mantle cell lymphoma |
Q43085095 | Maternal embryonic leucine zipper kinase is stabilized in mitosis by phosphorylation and is partially degraded upon mitotic exit |
Q30609345 | Maternal embryonic leucine zipper kinase regulates pancreatic ductal, but not β-cell, regeneration |
Q36905898 | Maternal embryonic leucine zipper kinase serves as a poor prognosis marker and therapeutic target in gastric cancer |
Q26738538 | Molecular mechanisms of peritoneal dissemination in gastric cancer |
Q28537936 | Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition |
Q36033101 | Murine protein serine-threonine kinase 38 activates p53 function through Ser15 phosphorylation |
Q27313731 | OTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic Kinases |
Q35068076 | Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia. |
Q46227422 | Protein kinase A modulates Cdc25B activity during meiotic resumption of mouse oocytes |
Q48664813 | Serine/threonine kinase, Melk, regulates proliferation and glial differentiation of retinal progenitor cells |
Q39242272 | Size Matters: How C. elegans Asymmetric Divisions Regulate Apoptosis |
Q41884226 | Small interfering RNA targeting CDC25B inhibits liver tumor growth in vitro and in vivo |
Q38706288 | Small molecules inhibit STAT3 activation, autophagy, and cancer cell anchorage-independent growth. |
Q53597964 | Spatial regulation of cytokinesis by the Kin1 and Pom1 kinases in fission yeast. |
Q36679284 | Stathmin involvement in the maternal embryonic leucine zipper kinase pathway in glioblastoma. |
Q27679427 | Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase |
Q24338012 | Substrate specificity and activity regulation of protein kinase MELK |
Q26739923 | Targeting DNA Replication Stress for Cancer Therapy |
Q34097169 | The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration. |
Q27681770 | The structures of the kinase domain and UBA domain of MPK38 suggest the activation mechanism for kinase activity |
Q64053382 | Thr55 phosphorylation of p21 by MPK38/MELK ameliorates defects in glucose, lipid, and energy metabolism in diet-induced obese mice |
Q30818142 | pEg6, a spire family member, is a maternal gene encoding a vegetally localized mRNA in Xenopus embryos |
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