| scholarly article | Q13442814 |
| P50 | author | Yūsuke Nakamura | Q11365872 |
| Toyomasa Katagiri | Q114328235 | ||
| P2093 | author name string | Meng-Lay Lin | |
| Jae-Hyun Park | |||
| Toshihiko Nishidate | |||
| P2860 | cites work | Bcl-G, a novel pro-apoptotic member of the Bcl-2 family | Q24290443 |
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| Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells | Q28201813 | ||
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| Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex | Q40626164 | ||
| Maternal embryonic leucine zipper kinase/murine protein serine-threonine kinase 38 is a promising therapeutic target for multiple cancers | Q42808469 | ||
| A pooled analysis of bone marrow micrometastasis in breast cancer | Q44594123 | ||
| Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray | Q48585236 | ||
| Cell cycle regulation of pEg3, a new Xenopus protein kinase of the KIN1/PAR-1/MARK family | Q48871311 | ||
| Breast cancer | Q56994859 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | carcinogenesis | Q1637543 |
| apoptotic process | Q14599311 | ||
| protein kinase binding | Q14817984 | ||
| BCL2 like 14 | Q21100297 | ||
| Maternal embryonic leucine zipper kinase | Q21173216 | ||
| P304 | page(s) | R17 | |
| P577 | publication date | 2007-01-01 | |
| P1433 | published in | Breast Cancer Research | Q2208481 |
| P1476 | title | Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family | |
| P478 | volume | 9 |
| Q36189422 | A crucial role for the phosphorylation of STRAP at Ser(188) by MPK38 in STRAP-dependent cell death through ASK1, TGF-β, p53, and PI3K/PDK1 signaling pathways |
| Q36627944 | A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells |
| Q37665199 | A potential molecular model for studying apoptosis enhanced by the interaction of BCL-G with JAB1 in swine |
| Q90221703 | A risk score staging system based on the expression of seven genes predicts the outcome of bladder cancer |
| Q42668143 | BCL-G as a new candidate gene for immune responses in pigs: bioinformatic analysis and functional characterization |
| Q36347191 | Bcl-2 family member Bcl-G is not a proapoptotic protein. |
| Q42404732 | Bcl-G acquitted of murder! |
| Q42108657 | CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials |
| Q64287313 | CRKL regulates alternative splicing of cancer-related genes in cervical cancer samples and HeLa cell |
| Q36643905 | Caenorhabditis elegans PIG-1/MELK acts in a conserved PAR-4/LKB1 polarity pathway to promote asymmetric neuroblast divisions |
| Q37233429 | Cell-cycle dependent localization of MELK and its new partner RACK1 in epithelial versus mesenchyme-like cells in Xenopus embryo |
| Q50123858 | Challenges in validating candidate therapeutic targets in cancer. |
| Q92068313 | Cloning, tissue distribution, expression pattern, and function of porcine maternal embryonic leucine zipper kinase |
| Q38703734 | Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with a focus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development. |
| Q38577467 | Cortical localization of maternal embryonic leucine zipper kinase (MELK) implicated in cytokinesis in early xenopus embryos |
| Q39686834 | Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells |
| Q42127507 | Detection of Bcl-2 family member Bcl-G in mouse tissues using new monoclonal antibodies. |
| Q34530885 | Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer |
| Q37360234 | Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer |
| Q41900139 | Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer |
| Q54107598 | Elucidating the Role of the Maternal Embryonic Leucine Zipper Kinase (MELK) in Adrenocortical Carcinoma. |
| Q39787251 | FAU regulates carboplatin resistance in ovarian cancer. |
| Q39543236 | FocalScan: Scanning for altered genes in cancer based on coordinated DNA and RNA change |
| Q42130307 | Fragment-based discovery of type I inhibitors of maternal embryonic leucine zipper kinase |
| Q92281756 | Gene Expression Assays for Early-Stage Hormone Receptor-Positive Breast Cancer: Understanding the Differences |
| Q38461663 | Gene expression profiling analysis of osteosarcoma cell lines |
| Q38680916 | Genetic compensation: A phenomenon in search of mechanisms. |
| Q38184928 | Genetics of breast cancer bone metastasis: a sequential multistep pattern |
| Q36289944 | Genome-wide effects of MELK-inhibitor in triple-negative breast cancer cells indicate context-dependent response with p53 as a key determinant |
| Q33503255 | Global gene expression profiling of human pleural mesotheliomas: identification of matrix metalloproteinase 14 (MMP-14) as potential tumour target |
| Q92978059 | Human BCL-G regulates secretion of inflammatory chemokines but is dispensable for induction of apoptosis by IFN-γ and TNF-α in intestinal epithelial cells |
| Q36684067 | Identification and prioritization of candidate genes for symptom variability in breast cancer survivors based on disease characteristics at the cellular level |
| Q92153843 | Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma |
| Q28115758 | Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy |
| Q37295309 | Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development |
| Q39973731 | Involvement of elevated expression of multiple cell-cycle regulator, DTL/RAMP (denticleless/RA-regulated nuclear matrix associated protein), in the growth of breast cancer cells |
| Q40066000 | Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis |
| Q47105077 | MELK Promotes Melanoma Growth by Stimulating the NF-κB Pathway |
| Q49701324 | MELK expression correlates with tumor mitotic activity but is not required for cancer growth. |
| Q38715935 | MELK expression in ovarian cancer correlates with poor outcome and its inhibition by OTSSP167 abrogates proliferation and viability of ovarian cancer cells |
| Q50994627 | MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells. |
| Q91779054 | MELK is Upregulated in Advanced Clear Cell Renal Cell Carcinoma and Promotes Disease Progression by Phosphorylating PRAS40 |
| Q33762222 | MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells. |
| Q41705554 | MELK is not necessary for the proliferation of basal-like breast cancer cells |
| Q92501934 | MELK promotes Endometrial carcinoma progression via activating mTOR signaling pathway |
| Q36275700 | MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells |
| Q35265941 | MELK-a conserved kinase: functions, signaling, cancer, and controversy |
| Q38648606 | MELK: a potential novel therapeutic target for TNBC and other aggressive malignancies. |
| Q35915969 | Major Functional Transcriptome of an Inferred Center Regulator of an ER(-) Breast Cancer Model System. |
| Q37099799 | Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells |
| Q27022633 | Maternal embryonic leucine zipper kinase (MELK): a novel regulator in cell cycle control, embryonic development, and cancer |
| Q33960305 | Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway |
| Q38701009 | Maternal embryonic leucine zipper kinase inhibits epithelial-mesenchymal transition by regulating transforming growth factor-β signaling |
| Q43085095 | Maternal embryonic leucine zipper kinase is stabilized in mitosis by phosphorylation and is partially degraded upon mitotic exit |
| Q37708563 | Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo |
| Q30609345 | Maternal embryonic leucine zipper kinase regulates pancreatic ductal, but not β-cell, regeneration |
| Q36905898 | Maternal embryonic leucine zipper kinase serves as a poor prognosis marker and therapeutic target in gastric cancer |
| Q99551774 | Maternal embryonic leucine zipper kinase: A novel biomarker and a potential therapeutic target in lung adenocarcinoma |
| Q28537936 | Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition |
| Q92465189 | Mutant P53 induces MELK expression by release of wild-type P53-dependent suppression of FOXM1 |
| Q36214336 | Network-based approach to identify prognostic biomarkers for estrogen receptor-positive breast cancer treatment with tamoxifen |
| Q35942699 | Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells |
| Q33880794 | Phosphorylation of the HIV-1 capsid by MELK triggers uncoating to promote viral cDNA synthesis. |
| Q33358309 | Pooling breast cancer datasets has a synergetic effect on classification performance and improves signature stability |
| Q35068076 | Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia. |
| Q38790859 | Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor |
| Q51049666 | Refinement of breast cancer risk prediction with concordant leading edge subsets from prognostic gene signatures. |
| Q30858189 | Robust selection of cancer survival signatures from high-throughput genomic data using two-fold subsampling |
| Q54978638 | Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK. |
| Q48664813 | Serine/threonine kinase, Melk, regulates proliferation and glial differentiation of retinal progenitor cells |
| Q35926133 | Sex hormones have pervasive effects on thymic epithelial cells. |
| Q35021326 | Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway |
| Q36679284 | Stathmin involvement in the maternal embryonic leucine zipper kinase pathway in glioblastoma. |
| Q27679427 | Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase |
| Q42553482 | Structure-Based Design of Type II Inhibitors Applied to Maternal Embryonic Leucine Zipper Kinase |
| Q30978083 | The Discovery of Novel Biomarkers Improves Breast Cancer Intrinsic Subtype Prediction and Reconciles the Labels in the METABRIC Data Set. |
| Q48147735 | The microRNA expression signature of small cell lung cancer: tumor suppressors of miR-27a-5p and miR-34b-3p and their targeted oncogenes. |
| Q27681770 | The structures of the kinase domain and UBA domain of MPK38 suggest the activation mechanism for kinase activity |
| Q40088699 | The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing. |
| Q64053382 | Thr55 phosphorylation of p21 by MPK38/MELK ameliorates defects in glucose, lipid, and energy metabolism in diet-induced obese mice |
| Q34044078 | Tumor-specific activation of the C-JUN/MELK pathway regulates glioma stem cell growth in a p53-dependent manner |
| Q37640266 | Zinc finger protein ZPR9 functions as an activator of AMPK-related serine/threonine kinase MPK38/MELK involved in ASK1/TGF-β/p53 signaling pathways |
| Q41709133 | p53-independent p21 induction by MELK inhibition |
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