review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | David Murray | |
Bonnie Andrais | |||
Razmik Mirzayans | |||
April Scott | |||
P2860 | cites work | Ataxia-telangiectasia and cellular responses to DNA damage. | Q40922688 |
Kinetics of the multidrug transporter (P-glycoprotein) and its reversal | Q41441350 | ||
Modulation of activity of the promoter of the human MDR1 gene by Ras and p53. | Q41643433 | ||
Altered gene expression in busulfan-resistant human myeloid leukemia | Q41885757 | ||
Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1 | Q22299424 | ||
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a) | Q24293520 | ||
Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes | Q24297874 | ||
A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis | Q24312492 | ||
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases | Q24319848 | ||
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways | Q24321528 | ||
Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death | Q24648216 | ||
Endopolyploidy in irradiated p53-deficient tumour cell lines: persistence of cell division activity in giant cells expressing Aurora-B kinase | Q24650663 | ||
Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer | Q24652941 | ||
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations | Q27730815 | ||
TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence. | Q27851687 | ||
WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
Dysregulation of cellular signaling by HER2/neu in breast cancer | Q28183609 | ||
Phospholipase D in cell proliferation and cancer | Q28205631 | ||
Tying it all together: epigenetics, genetics, cell cycle, and cancer | Q28251486 | ||
Cell death by mitotic catastrophe: a molecular definition | Q28255830 | ||
p21 is a universal inhibitor of cyclin kinases | Q28257305 | ||
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53 | Q28266637 | ||
Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells: implications for chemotherapy | Q28272930 | ||
Targeting the dynamic HSP90 complex in cancer | Q28288602 | ||
Cellular responses to DNA damage: cell-cycle checkpoints, apoptosis and the roles of p53 and ATM | Q28611443 | ||
Blinded by the Light: The Growing Complexity of p53 | Q29547590 | ||
Requirement for p53 and p21 to sustain G2 arrest after DNA damage | Q29547667 | ||
Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway | Q42812297 | ||
Q&A: Cancer: clues from cell metabolism | Q43045797 | ||
Involvement of phospholipase D in sphingosine 1-phosphate-induced activation of phosphatidylinositol 3-kinase and Akt in Chinese hamster ovary cells overexpressing EDG3. | Q43684832 | ||
Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic | Q43882655 | ||
Nuclear envelope-limited chromatin sheets are part of mitotic death | Q43933778 | ||
2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism. | Q44480775 | ||
PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1. | Q44678852 | ||
2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo | Q44732835 | ||
Exploring mechanisms of the DNA-damage response: p53 pulses and their possible relevance to apoptosis. | Q44926431 | ||
Autophagy, senescence and tumor dormancy in cancer therapy | Q44950633 | ||
Enhancement of radiation response in p53-deficient cancer cells by the Aurora-B kinase inhibitor AZD1152. | Q46847084 | ||
Ultraviolet light exposure triggers nuclear accumulation of p21(WAF1) and accelerated senescence in human normal and nucleotide excision repair-deficient fibroblast strains | Q46982682 | ||
Aberrant p21WAF1-dependent growth arrest as the possible mechanism of abnormal resistance to ultraviolet light cytotoxicity in Li-Fraumeni syndrome fibroblast strains heterozygous for TP53 mutations | Q47684754 | ||
A nuclear budding mechanism in transiently arrested cells generates drug-sensitive and drug-resistant cells. | Q47738952 | ||
Radiosensitivity in ataxia telangiectasia fibroblasts is not associated with deregulated apoptosis | Q47895763 | ||
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen | Q48084448 | ||
BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death. | Q48478195 | ||
Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. | Q50335767 | ||
Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio. | Q52546877 | ||
p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation. | Q53554846 | ||
Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer. | Q53620789 | ||
Single-cell analysis of p16(INK4a) and p21(WAF1) expression suggests distinct mechanisms of senescence in normal human and Li-Fraumeni Syndrome fibroblasts. | Q54701406 | ||
Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73 | Q58073315 | ||
Wild-type human p53 activates the human epidermal growth factor receptor promoter | Q72351836 | ||
Control of E2F activity by p21Waf1/Cip1 | Q73023858 | ||
At the end of the millennium, a view of the end | Q73225990 | ||
Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription | Q73615893 | ||
p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation | Q79405060 | ||
Optimization of halopemide for phospholipase D2 inhibition | Q79816958 | ||
p73 suppresses polyploidy and aneuploidy in the absence of functional p53 | Q80813940 | ||
Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells | Q81419187 | ||
p53-based anti-cancer therapies: An empty promise? | Q84911725 | ||
Restoration of p53 function leads to tumour regression in vivo | Q29618727 | ||
Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis | Q31983511 | ||
Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells | Q32084034 | ||
Mutant p53 gain-of-function in cancer | Q33687048 | ||
p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation | Q33855418 | ||
Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress | Q33997846 | ||
Phospholipase D-mTOR requirement for the Warburg effect in human cancer cells | Q34440418 | ||
TP53 mutations in nonsmall cell lung cancer | Q34559185 | ||
If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells | Q34625589 | ||
Novel targets of Akt, p21(Cipl/WAF1), and MDM2. | Q34759285 | ||
Activation of meiosis-specific genes is associated with depolyploidization of human tumor cells following radiation-induced mitotic catastrophe. | Q34956023 | ||
Wild-type and mutant p53 proteins interact with mitochondrial caspase-3 | Q35001142 | ||
Two-phase dynamics of p53 in the DNA damage response. | Q35022037 | ||
The p53-Mdm2 module and the ubiquitin system. | Q35036580 | ||
Tumor cell senescence in cancer treatment | Q35143435 | ||
Targeting Aurora-2 kinase in cancer. | Q35157030 | ||
Targeting PI3K-AKT pathway for cancer therapy | Q35648847 | ||
Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases | Q35680797 | ||
Hallmarks of senescence in carcinogenesis and cancer therapy | Q35743144 | ||
The p53 response to DNA damage | Q35848498 | ||
PI3K/Akt/mTOR pathway as a target for cancer therapy | Q36227186 | ||
Neosis--a paradigm of self-renewal in cancer | Q36326465 | ||
The complexity of p53 stabilization and activation | Q36443523 | ||
p53 as a target for anti-cancer drug development. | Q36475676 | ||
p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents | Q36605767 | ||
Phospholipase D elevates the level of MDM2 and suppresses DNA damage-induced increases in p53. | Q36732919 | ||
Phospholipase D provides a survival signal in human cancer cells with activated H-Ras or K-Ras | Q36745757 | ||
Cell fate decision mediated by p53 pulses | Q37262599 | ||
Dichloroacetate induces apoptosis in endometrial cancer cells. | Q37328044 | ||
Low-dose radiation-induced senescent stromal fibroblasts render nearby breast cancer cells radioresistant | Q37354811 | ||
Mutant p53 mediates survival of breast cancer cells | Q37424034 | ||
Cellular Senescence - its role in cancer and the response to ionizing radiation | Q37915652 | ||
EGF receptor inhibition radiosensitizes NSCLC cells by inducing senescence in cells sustaining DNA double-strand breaks | Q38609721 | ||
Mitochondrial regulation of cell death: mitochondria are essential for procaspase 3-p21 complex formation to resist Fas-mediated cell death | Q39446000 | ||
Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domain | Q39575066 | ||
p21(WAF1) is component of a positive feedback loop that maintains the p53 transcriptional program. | Q39582775 | ||
Time-dependently expressed markers and the characterization for premature senescence induced by ionizing radiation in MCF7. | Q39685860 | ||
Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells | Q39730167 | ||
Apoptotic signalling in HeLa Hep2 cells following 5 Gy of cobalt-60 gamma radiation. | Q39759574 | ||
Involvement of p21Waf1/Cip1 cleavage during roscovitine-induced apoptosis in non-small cell lung cancer cells. | Q39767769 | ||
BIIB021, a novel Hsp90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy | Q39815503 | ||
The role of meiotic cohesin REC8 in chromosome segregation in gamma irradiation-induced endopolyploid tumour cells | Q39848059 | ||
Sensitization to gamma-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells | Q39875544 | ||
p21Cip1/WAF1 mediates cyclin B1 degradation in response to DNA damage | Q39892611 | ||
Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation | Q39957013 | ||
Histone deacetylase inhibition and blockade of the glycolytic pathway synergistically induce glioblastoma cell death | Q39981751 | ||
Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage. | Q39983426 | ||
Dichloroacetate (DCA) sensitizes both wild-type and over expressing Bcl-2 prostate cancer cells in vitro to radiation | Q39984345 | ||
Capsaicin induces apoptosis and terminal differentiation in human glioma A172 cells | Q39992839 | ||
p53-dependent repression of the human MCL-1 gene encoding an anti-apoptotic member of the BCL-2 family: the role of Sp1 and of basic transcription factor binding sites in the MCL-1 promoter | Q40022446 | ||
Suppression of TGF-beta signaling by phospholipase D. | Q40046108 | ||
RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model | Q40106656 | ||
Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D. | Q40265316 | ||
Radiation-induced caspase-8 mediates p53-independent apoptosis in glioma cells | Q40291647 | ||
Phospholipase D couples survival and migration signals in stress response of human cancer cells | Q40295842 | ||
mTOR-dependent suppression of protein phosphatase 2A is critical for phospholipase D survival signals in human breast cancer cells | Q40383681 | ||
Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells. | Q40400655 | ||
CDK2 translational down-regulation during endothelial senescence | Q40415938 | ||
Differential regulation of MDR1 transcription by the p53 family members. Role of the DNA binding domain. | Q40474411 | ||
Induction of accelerated senescence by gamma radiation in human solid tumor-derived cell lines expressing wild-type TP53. | Q40479643 | ||
Alternative phospholipase D/mTOR survival signal in human breast cancer cells | Q40484574 | ||
p21/CDKN1A mediates negative regulation of transcription by p53. | Q40647697 | ||
Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin | Q40747055 | ||
Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1. | Q40788757 | ||
Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts | Q40812808 | ||
Tumor-derived p53 mutant C174Y is a gain-of-function mutant which activates the fos promoter and enhances colony formation | Q40852695 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P921 | main subject | cancer | Q12078 |
phosphoprotein | Q423934 | ||
signal transduction | Q828130 | ||
neoplasm | Q1216998 | ||
transport protein | Q2111029 | ||
DNA-binding protein | Q2252764 | ||
DNA damage | Q5205747 | ||
nuclear protein | Q16860021 | ||
neoplasm protein | Q66894191 | ||
P304 | page(s) | 170325 | |
P577 | publication date | 2012-07-15 | |
P1433 | published in | Journal of Biomedicine and Biotechnology | Q15752146 |
P1476 | title | New insights into p53 signaling and cancer cell response to DNA damage: implications for cancer therapy | |
P478 | volume | 2012 |
Q36677729 | A novel p21 attenuator which is structurally related to sorafenib |
Q53224664 | ATM may be a protective factor in endometrial carcinogenesis with the progesterone pathway. |
Q38951017 | AZD1152-HQPA induces growth arrest and apoptosis in androgen-dependent prostate cancer cell line (LNCaP) via producing aneugenic micronuclei and polyploidy. |
Q39232300 | Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells. |
Q38846458 | Adenovirus-mediated FIR demonstrated TP53-independent cell-killing effect and enhanced antitumor activity of carbon-ion beams |
Q42330184 | Anti-proliferative and pro-apoptotic effects of GHRH antagonists in prostate cancer |
Q35227654 | Anticancer effect of icaritin on human lung cancer cells through inducing S phase cell cycle arrest and apoptosis |
Q36193815 | Association between the cytogenetic profile of tumor cells and response to preoperative radiochemotherapy in locally advanced rectal cancer. |
Q33596688 | Association of intron and exon polymorphisms of p53 gene in Iranian patients with gastritis |
Q41990517 | Association of p53 and p21 polymorphisms with prostate cancer |
Q91283843 | Bioengineered tumor microenvironments with naked mole rats high-molecular-weight hyaluronan induces apoptosis in breast cancer cells |
Q54120043 | Bioinformatics Based Therapeutic Effects of Sinomenium Acutum. |
Q38672393 | CADASIL mutant NOTCH3(R90C) decreases the viability of HS683 oligodendrocytes via apoptosis |
Q36512388 | CHMP4C Disruption Sensitizes the Human Lung Cancer Cells to Irradiation |
Q39062425 | Cell cycle delay in murine pre-osteoblasts is more pronounced after exposure to high-LET compared to low-LET radiation |
Q26771165 | Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization |
Q27692108 | Cellular stress response and innate immune signaling: integrating pathways in host defense and inflammation. |
Q47757303 | Combination of cheminformatics and bioinformatics to explore the chemical basis of the rhizomes and aerial parts of Dioscorea nipponica Makino |
Q47739187 | Comparative transcriptomic analysis of skeletal muscle tissue during prenatal stages in Tongcheng and Yorkshire pig using RNA-seq |
Q48297523 | DNA damage responses and p53 in the aging process. |
Q38932426 | Damnacanthal is a potent inducer of apoptosis with anticancer activity by stimulating p53 and p21 genes in MCF-7 breast cancer cells. |
Q90438536 | Defenses against Pro-oxidant Forces - Maintenance of Cellular and Genomic Integrity and Longevity |
Q28567929 | Diabetes-induced oxidative DNA damage alters p53-p21CIP1/Waf1 signaling in the rat testis |
Q48527876 | Dicer1 Ablation Impairs Responsiveness of Cerebellar Granule Neuron Precursors to Sonic Hedgehog and Disrupts Expression of Distinct Cell Cycle Regulator Genes |
Q37277915 | Distal airway epithelial progenitor cells are radiosensitive to High-LET radiation |
Q35557768 | Downregulated Long Noncoding RNA BANCR Promotes the Proliferation of Colorectal Cancer Cells via Downregualtion of p21 Expression |
Q53595525 | Dynamic p53 protein expression and phosphorylation in the kidneys of rats that experienced intrauterine growth restriction. |
Q38626547 | EZH2 silencing with RNA interference induces G2/M arrest in human lung cancer cells in vitro |
Q35168165 | Effects of in vitro exposure to diarrheic toxin producer Prorocentrum lima on gene expressions related to cell cycle regulation and immune response in Crassostrea gigas |
Q52726503 | Etoposide radiosensitizes p53-defective cholangiocarcinoma cell lines independent of their G2 checkpoint efficacies. |
Q38695464 | Expression of TAG1/APP signaling pathway in the proliferation and differentiation of glioma stem cells |
Q35940296 | Feedbacks, Bifurcations, and Cell Fate Decision-Making in the p53 System |
Q33751085 | Gene and miRNA expression profiles of mouse Lewis lung carcinoma LLC1 cells following single or fractionated dose irradiation. |
Q51508722 | Genome wide expression analysis of radiation-induced DNA damage responses in isogenic HCT116 p53+/+ and HCT116 p53-/- colorectal carcinoma cell lines. |
Q58802460 | Genomic instability in mutant p53 cancer cells upon entotic engulfment |
Q57165992 | Growth hormone-releasing hormone receptor antagonists modify molecular machinery in the progression of prostate cancer |
Q92288917 | Human mesenchymal stem cells are resistant to UV-B irradiation |
Q36035951 | Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu). |
Q30585968 | Immortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like state. |
Q50934685 | Immunoprofiling of oral squamous cell carcinomas reveals high p63 and survivin expression. |
Q38086861 | Impact of EBV essential nuclear protein EBNA-3C on B-cell proliferation and apoptosis |
Q43084011 | In vitro anticancer effect of venom from Cuban scorpion Rhopalurus junceus against a panel of human cancer cell lines |
Q55385538 | Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis. |
Q49909509 | Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells |
Q35234195 | Intracellular oxidant activity, antioxidant enzyme defense system, and cell senescence in fibroblasts with trisomy 21. |
Q35102038 | Investigation of anti-cancer mechanisms by comparative analysis of naked mole rat and rat. |
Q38162722 | Ionizing radiation-induced responses in human cells with differing TP53 status |
Q52976397 | Isoliquiritigenin as a cause of DNA damage and inhibitor of ataxia-telangiectasia mutated expression leading to G2/M phase arrest and apoptosis in oral squamous cell carcinoma. |
Q38796134 | Key Issues Related to Cryopreservation and Storage of Stem Cells and Cancer Stem Cells: Protecting Biological Integrity |
Q95840243 | Kinesin light chain 4 as a new target for lung cancer chemoresistance via targeted inhibition of checkpoint kinases in the DNA repair network |
Q52951920 | Light-mediated DNA Repair Prevents UVB-induced Cell Cycle Arrest in Embryos of the Crustacean Macrobrachium olfersi. |
Q92441295 | Lipophilized Epigallocatechin Gallate Derivative Exerts Anti-Proliferation Efficacy through Induction of Cell Cycle Arrest and Apoptosis on DU145 Human Prostate Cancer Cells |
Q34000404 | MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress |
Q46599463 | Marine steroid derived from Acropora formosa enhances mitochondrial-mediated apoptosis in non-small cell lung cancer cells |
Q37099799 | Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells |
Q39137795 | MicroRNA-17-5p post-transcriptionally regulates p21 expression in irradiated betel quid chewing-related oral squamous cell carcinoma cells. |
Q37588307 | MicroRNA-17-5p regulated apoptosis-related protein expression and radiosensitivity in oral squamous cell carcinoma caused by betel nut chewing |
Q43184280 | MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma |
Q38097384 | MicroRNAs involved in chemo- and radioresistance of high-grade gliomas |
Q39062038 | Modulation of p53 expression using antisense oligonucleotides complementary to the 5'-terminal region of p53 mRNA in vitro and in the living cells |
Q33584432 | Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathways |
Q38716153 | Multinucleated Giant Cancer Cells Produced in Response to Ionizing Radiation Retain Viability and Replicate Their Genome |
Q53230348 | Multiple mucin depleted foci, high proliferation and low apoptotic response in the onset of colon carcinogenesis of the PIRC rat, mutated in Apc. |
Q60961343 | Novel Clofarabine-Based Combinations with Polyphenols Epigenetically Reactivate Retinoic Acid Receptor Beta, Inhibit Cell Growth, and Induce Apoptosis of Breast Cancer Cells |
Q26749382 | Oncogenic Intra-p53 Family Member Interactions in Human Cancers |
Q37030305 | PXR interaction with p53: a meeting of two masters |
Q39062283 | Part I-mechanism of adaptation: high nitric oxide adapted A549 cells show enhanced DNA damage response and activation of antiapoptotic pathways |
Q38706500 | Partial p53-dependence of anisomycin-induced apoptosis in PC12 cells |
Q89040090 | Pharmacological Targeting of Cell Cycle, Apoptotic and Cell Adhesion Signaling Pathways Implicated in Chemoresistance of Cancer Cells |
Q88477742 | Photobiomodulation effects on mRNA levels from genomic and chromosome stabilization genes in injured muscle |
Q37540974 | Potential Urinary Protein Biomarker Candidates for the Accurate Detection of Prostate Cancer among Benign Prostatic Hyperplasia Patients |
Q36828178 | Preclinical Efficacy of the MDM2 Inhibitor RG7112 in MDM2-Amplified and TP53 Wild-type Glioblastomas |
Q38432883 | RNA-based ovarian cancer research from 'a gene to systems biomedicine' perspective. |
Q47099105 | Rhopalurus junceus scorpion venom induces apoptosis in the triple negative human breast cancer cell line MDA-MB-231. |
Q26752541 | Role of EBNA-3 Family Proteins in EBV Associated B-cell Lymphomagenesis |
Q42286334 | Role of p16(INK4A) in Replicative Senescence and DNA Damage-Induced Premature Senescence in p53-Deficient Human Cells |
Q33889417 | Roles of long noncoding RNAs in colorectal cancer metastasis |
Q38714239 | Selenium supplementation modulates apoptotic processes in thyroid follicular cells |
Q39730306 | Self-aggregating TIAF1 in lung cancer progression. |
Q34294283 | Short hairpin RNA library-based functional screening identified ribosomal protein L31 that modulates prostate cancer cell growth via p53 pathway |
Q39269601 | Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome |
Q27027835 | Small molecule compounds targeting the p53 pathway: are we finally making progress? |
Q38980408 | Spatial and temporal distribution of γH2AX fluorescence in human cell cultures following synchrotron-generated X-ray microbeams: lack of correlation between persistent γH2AX foci and apoptosis. |
Q38871254 | Spontaneous γH2AX Foci in Human Solid Tumor-Derived Cell Lines in Relation to p21WAF1 and WIP1 Expression |
Q37162388 | Stress-induced isoforms of MDM2 and MDM4 correlate with high-grade disease and an altered splicing network in pediatric rhabdomyosarcoma |
Q36674097 | Structural studies of UBXN2A and mortalin interaction and the putative role of silenced UBXN2A in preventing response to chemotherapy |
Q61795681 | Synthesis, Anticancer Activity, and Apoptosis Induction of Novel 3,6-Diazaphenothiazines |
Q34413200 | Systematic analysis of time-series gene expression data on tumor cell-selective apoptotic responses to HDAC inhibitors |
Q37636824 | TP53 hot spot mutations in ovarian cancer: selective resistance to microtubule stabilizers in vitro and differential survival outcomes from The Cancer Genome Atlas |
Q38088935 | The ATM protein kinase: regulating the cellular response to genotoxic stress, and more |
Q36948856 | The DNA damage response in mammalian oocytes. |
Q33739235 | The G2 checkpoint inhibitor CBP-93872 increases the sensitivity of colorectal and pancreatic cancer cells to chemotherapy |
Q26749064 | The Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival? |
Q38796786 | The downregulation of the RNA-binding protein Staufen2 in response to DNA damage promotes apoptosis |
Q50000255 | The effect of "NutramilTM Complex," food for special medical purpose, on breast and prostate carcinoma cells |
Q33881257 | The genotype-dependent influence of functionalized multiwalled carbon nanotubes on fetal development |
Q41861305 | The interfaces between signal transduction pathways: IGF-1/mTor, p53 and the Parkinson Disease pathway |
Q34846077 | The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest. |
Q35224002 | The p53-reactivating small molecule RITA induces senescence in head and neck cancer cells |
Q38926422 | The proteasome inhibitor Bortezomib (Velcade) as potential inhibitor of estrogen receptor-positive breast cancer. |
Q39117690 | The protein p17 signaling pathways in cancer |
Q38738437 | The regrowth kinetic of the surviving population is independent of acute and chronic responses to temozolomide in glioblastoma cell lines |
Q28072553 | The role of p53 in cancer drug resistance and targeted chemotherapy |
Q38981518 | The role of the p53 protein in nitrosative stress-induced apoptosis of PC12 rat pheochromocytoma cells |
Q90174223 | Transcription factorIRX5 promotes hepatocellular carcinoma proliferation and inhibits apoptosis by regulating the p53 signalling pathway |
Q51063068 | Up-regulation of Smurf1 after spinal cord injury in adult rats. |
Q64070958 | Ursolic Acid Induces Apoptotic Cell Death Through AIF and Endo G Release Through a Mitochondria-dependent Pathway in NCI-H292 Human Lung Cancer Cells |
Q28550980 | Vorinostat Enhances Cytotoxicity of SN-38 and Temozolomide in Ewing Sarcoma Cells and Activates STAT3/AKT/MAPK Pathways |
Q57848625 | deletion in luminal cells of mature prostate induces replication stress and senescence in vivo |
Q55069151 | p21, p53, TP53BP1 and p73 polymorphisms and the risk of gastric cardia adenocarcinoma in a Chinese population. |
Search more.