The histone variant macroH2A1.1 is recruited to DSBs through a mechanism involving PARP1.

scientific article published on 29 September 2012

The histone variant macroH2A1.1 is recruited to DSBs through a mechanism involving PARP1. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.FEBSLET.2012.09.030
P932PMC publication ID3491562
P698PubMed publication ID23031826
P5875ResearchGate publication ID231861447

P2093author name stringChang Xu
Ye Xu
Brendan D Price
Ozge Gursoy-Yuzugullu
P2860cites workAlternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repairQ21145054
The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencingQ22001529
Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1Q24321560
Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodelerQ24655668
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activationQ27657009
Highly efficient endogenous human gene correction using designed zinc-finger nucleasesQ28243157
Histone variants--ancient wrap artists of the epigenomeQ28274796
Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaksQ28286203
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sitesQ28304648
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaksQ29465538
PARP inhibition: PARP1 and beyondQ29619617
Activation of Hif1α by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivityQ34053479
53BP1, a mediator of the DNA damage checkpointQ34153067
The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repairQ34191583
The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activityQ35204751
Regulatory ubiquitylation in response to DNA double-strand breaksQ37397281
The ubiquitin landscape at DNA double-strand breaksQ37425595
Multiple facets of the unique histone variant macroH2A: from genomics to cell biologyQ37764645
Chromatin dynamics and the repair of DNA double strand breaksQ37826623
More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenanceQ37942059
The DNA damage response and cancer therapyQ37977004
Poly(ADP-ribose) polymerase 1 is inhibited by a histone H2A variant, MacroH2A, and contributes to silencing of the inactive X chromosome.Q40166664
The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM.Q40294245
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobilityQ41919899
Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.Q42672338
Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrestQ42738049
P433issue21
P407language of work or nameEnglishQ1860
P304page(s)3920-3925
P577publication date2012-09-29
P1433published inFEBS LettersQ1388051
P1476titleThe histone variant macroH2A1.1 is recruited to DSBs through a mechanism involving PARP1.
P478volume586

Reverse relations

cites work (P2860)
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Q34984011Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy
Q35200061Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells.
Q95324882Histone H2A variants alpha1-extension helix directs RNF168-mediated ubiquitination
Q27021264Histone variants: the tricksters of the chromatin world
Q38086003Macro domains as metabolite sensors on chromatin.
Q59795966MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20
Q38604897Molecular and Biochemical Methods Useful for the Epigenetic Characterization of Chromatin-Associated Proteins in Bivalve Molluscs
Q41477550NF-κB-dependent DNA damage-signaling differentially regulates DNA double-strand break repair mechanisms in immature and mature human hematopoietic cells
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Q36108353Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes
Q38069879Reprogramming cellular events by poly(ADP-ribose)-binding proteins
Q37418010Reshaping chromatin after DNA damage: the choreography of histone proteins
Q42374197Spatially restricted loading of BRD2 at DNA double-strand breaks protects H4 acetylation domains and promotes DNA repair
Q41983765The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment.
Q38848092The nucleosome: orchestrating DNA damage signaling and repair within chromatin.
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Q90566316The taming of PARP1 and its impact on NAD+ metabolism
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Q41967452ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair

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