Buried territories: heterochromatic response to DNA double-strand breaks

scientific article published on 4 May 2016

Buried territories: heterochromatic response to DNA double-strand breaks is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1093/ABBS/GMW033
P698PubMed publication ID27151295

P2093author name stringNa Kong
Xiu-Jun Cai
Ji-Feng Xiang
An-Yong Xie
Yi-Li Feng
P2860cites workThe mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayQ22065419
The role of heterochromatin in centromere functionQ22065919
DNA Damage, Aging, and CancerQ22121931
Finishing the euchromatic sequence of the human genomeQ22122488
Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosisQ24290159
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteinsQ24300411
The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domainQ24301692
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damageQ24306743
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damageQ24309181
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteinsQ24309287
KAP1, a novel substrate for PIKK family members, colocalizes with numerous damage response factors at DNA lesionsQ24337449
PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repairQ24337719
Genetic toxicology of oxygenQ38683020
Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks.Q39012832
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repairQ39750906
Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex.Q39752528
gamma-radiation-induced gammaH2AX formation occurs preferentially in actively transcribing euchromatic lociQ39783117
Recruitment of heterochromatin protein 1 to DNA repair sites.Q39845515
The impact of heterochromatin on DSB repairQ39851599
Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repressionQ40066661
Chromatin dynamics during DSB repairQ40081910
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathwayQ40252252
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesionsQ40495236
Radiation-induced chromosome aberrations in human euchromatic (17cen-p53) and heterochromatic (1cen-1q12) regionsQ40797094
Misrejoining of DNA double-strand breaks in primary and transformed human and rodent cells: a comparison between the HPRT region and other genomic locationsQ40952042
The histone variant macroH2A1.1 is recruited to DSBs through a mechanism involving PARP1.Q41425376
Control of sister chromatid recombination by histone H2AX.Q41549984
The H4 tail domain participates in intra- and internucleosome interactions with protein and DNA during folding and oligomerization of nucleosome arraysQ41888720
DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A.Q42101728
KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response.Q42152404
Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repairQ42418108
Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.Q42672338
Distribution of breakpoints induced by etoposide and X-rays along the CHO X chromosomeQ44909817
Non-random distribution of DNA double-strand breaks induced by particle irradiationQ46120762
Chromatin structure influences the sensitivity of DNA to gamma-radiationQ46427208
HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response.Q46625510
End-joining of blunt DNA double-strand breaks in mammalian fibroblasts is precise and requires DNA-PK and XRCC4.Q49172985
The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repairQ24537586
A comprehensive catalog of human KRAB-associated zinc finger genes: insights into the evolutionary history of a large family of transcriptional repressorsQ24546068
Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essentialQ24551928
The DNA-damage response in human biology and diseaseQ24606586
Megabase chromatin domains involved in DNA double-strand breaks in vivoQ24680284
Linking replication stress with heterochromatin formationQ26778138
Not All DDRs Are Created Equal: Non-Canonical DNA Damage ResponsesQ26796371
DNA-PK: a dynamic enzyme in a versatile DSB repair pathwayQ26866928
Sources of DNA double-strand breaks and models of recombinational DNA repairQ27005814
Multiple cellular mechanisms prevent chromosomal rearrangements involving repetitive DNAQ27012760
The DNA Damage Response: Making It Safe to Play with KnivesQ27861055
Chromatin modifications and their functionQ27861067
Constitutive heterochromatin formation and transcription in mammalsQ28080683
The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosisQ28081821
Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repairQ28085622
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139Q28131715
Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stressQ28201846
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaksQ28235091
Development and applications of CRISPR-Cas9 for genome engineeringQ28241526
Mechanism of homologous recombination: mediators and helicases take on regulatory functionsQ28259452
The DNA damage response: ten years afterQ28261230
A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATMQ28270543
Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaksQ28286203
Nuclear organization of the genome and the potential for gene regulationQ28303751
Chromatin compaction protects genomic DNA from radiation damageQ28534299
Genomic instability in mice lacking histone H2AXQ28589826
Double strand break repair functions of histone H2AXQ28661754
Role of mammalian Mre11 in classical and alternative nonhomologous end joiningQ28751872
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damageQ29614218
Histone H4-K16 acetylation controls chromatin structure and protein interactionsQ29614521
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaksQ29617463
Histones: annotating chromatinQ29619913
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaksQ30480374
Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair.Q30524137
gammaH2AX foci form preferentially in euchromatin after ionising-radiation.Q33303665
Higher-order chromatin structure in DSB induction, repair and misrepairQ37689982
ATR: a master conductor of cellular responses to DNA replication stressQ37800265
Heterochromatin and the DNA damage response: the need to relaxQ37843473
KAP1 protein: an enigmatic master regulator of the genomeQ37886421
Histone marks: repairing DNA breaks within the context of chromatinQ37995722
Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaksQ38051860
The heterochromatic barrier to DNA double strand break repair: how to get the entry visaQ38056496
The role of the nucleosome acidic patch in modulating higher order chromatin structureQ38085143
The ATM protein kinase: regulating the cellular response to genotoxic stress, and moreQ38088935
Chromatin remodeling at DNA double-strand breaksQ38090114
DNA damage sensing by the ATM and ATR kinases.Q38134064
INO80-C and SWR-C: guardians of the genomeQ38275882
Mechanisms of ATM ActivationQ38314959
The Ku heterodimer: function in DNA repair and beyondQ38385852
Patching Broken DNA: Nucleosome Dynamics and the Repair of DNA BreaksQ38655184
The redundancy of the mammalian heterochromatic compartmentQ38680093
MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.Q33569624
Histone demethylase KDM5B is a key regulator of genome stabilityQ33627079
Chromatin as dynamic 10-nm fibersQ33651467
The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damageQ33678587
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damageQ33715275
DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatinQ33834990
HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repairQ33862272
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AXQ34031720
A macrohistone variant links dynamic chromatin compaction to BRCA1-dependent genome maintenance.Q34132182
Controlling the double helixQ34172152
Chromosome territories--a functional nuclear landscape.Q34523990
Activation of DNA damage response signaling by condensed chromatinQ34713712
Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repairQ34759375
30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone evictionQ34800325
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatinQ34801409
Repair of endogenous DNA damageQ35132488
A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription FactorsQ35640249
A decade of 3C technologies: insights into nuclear organizationQ35674570
HP1 and the dynamics of heterochromatin maintenanceQ35741016
Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differencesQ36037736
Heterochromatin is refractory to gamma-H2AX modification in yeast and mammalsQ36118803
A brief review of nucleosome structureQ36137489
The mechanism of telomere protection: a comparison between Drosophila and humans.Q36192029
Heterochromatic breaks move to the nuclear periphery to continue recombinational repair.Q36235927
Repeat instability: mechanisms of dynamic mutationsQ36277189
DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activityQ36316482
Regulation of the H4 tail binding and folding landscapes via Lys-16 acetylation.Q36397739
Chromatin structure outside and inside the nucleusQ36570241
Facultative heterochromatin: is there a distinctive molecular signature?Q36971377
Live cell microscopy analysis of radiation-induced DNA double-strand break motion.Q37096613
Heterochromatin protein 1 is recruited to various types of DNA damage.Q37263966
Nuclear dynamics of radiation-induced foci in euchromatin and heterochromatinQ37338520
Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin.Q37347174
The emerging role of HP1 in the DNA damage responseQ37452573
P433issue7
P304page(s)594-602
P577publication date2016-05-04
P1433published inActa Biochimica et Biophysica SinicaQ2183997
P1476titleBuried territories: heterochromatic response to DNA double-strand breaks
P478volume48

Reverse relations

cites work (P2860)
Q47614748A special issue on the DNA damage response and genomic instability
Q33574854A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress
Q37666874E3 ligase UHRF2 stabilizes the acetyltransferase TIP60 and regulates H3K9ac and H3K14ac via RING finger domain
Q47135566H2AX facilitates classical non-homologous end joining at the expense of limited nucleotide loss at repair junctions
Q64389148Is Required for Both Mitotic and Meiotic Recombination in Maize
Q28067125Repair of DNA Double-Strand Breaks in Heterochromatin
Q92864350SIRT6 coordinates with CHD4 to promote chromatin relaxation and DNA repair
Q58802841Using Persistent Homology as a New Approach for Super-Resolution Localization Microscopy Data Analysis and Classification of γH2AX Foci/Clusters

Search more.