| scholarly article | Q13442814 |
| P50 | author | Kai Rothkamm | Q39034555 |
| P2093 | author name string | Penny A Jeggo | |
| Markus Löbrich | |||
| Enriqueta Riballo | |||
| Martin Kühne | |||
| Nicole Rief | |||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 500-508 | |
| P577 | publication date | 2004-01-01 | |
| P1433 | published in | Cancer Research | Q326097 |
| P1476 | title | A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity | |
| P478 | volume | 64 |
| Q39455136 | A Process of Resection-Dependent Nonhomologous End Joining Involving the Goddess Artemis |
| Q21245223 | A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose |
| Q51914283 | A mathematical model of P53 gene regulatory networks under radiotherapy. |
| Q28476006 | ATM Limits Incorrect End Utilization during Non-Homologous End Joining of Multiple Chromosome Breaks |
| Q90006433 | ATM Loss Confers Greater Sensitivity to ATR Inhibition than PARP Inhibition in Prostate Cancer |
| Q24647310 | ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2 |
| Q41913571 | ATM specifically mediates repair of double-strand breaks with blocked DNA ends |
| Q34142115 | ATM-NF-kappaB connection as a target for tumor radiosensitization |
| Q36382754 | ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection |
| Q33283998 | ATM-mediated transcriptional and developmental responses to gamma-rays in Arabidopsis |
| Q36411149 | ATR signaling can drive cells into senescence in the absence of DNA breaks |
| Q41135787 | Abrogation of radioresistance in glioblastoma stem-like cells by inhibition of ATM kinase |
| Q34037211 | Alkylation DNA damage in combination with PARP inhibition results in formation of S-phase-dependent double-strand breaks. |
| Q42543961 | Analysis of Residual DSBs in Ataxia-Telangiectasia Lymphoblast Cells Initiating Apoptosis |
| Q41068321 | Application of the local effect model to predict DNA double-strand break rejoining after photon and high-LET irradiation. |
| Q33807557 | Assessing Candidate Gene nsSNPs for Phenotypic Differences in Double-Strand Break Repair Using Radiation-Induced gammaH2A.X Foci |
| Q35668905 | Association between Single Nucleotide Polymorphisms in XRCC3 and Radiation-Induced Adverse Effects on Normal Tissue: A Meta-Analysis |
| Q53581072 | Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break. |
| Q36210940 | Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism. |
| Q37605239 | Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A. |
| Q36121723 | BCLAF1 is a radiation-induced H2AX-interacting partner involved in γH2AX-mediated regulation of apoptosis and DNA repair |
| Q40156602 | BGRT: biologically guided radiation therapy-the future is fast approaching! |
| Q39849267 | Breaks invisible to the DNA damage response machinery accumulate in ATM-deficient cells. |
| Q47298461 | Caspase cleavage of transcription factor Sp1 enhances apoptosis |
| Q53572324 | Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair. |
| Q24683383 | Chromosome breakage after G2 checkpoint release |
| Q37000957 | Correlation of dynamic changes in γ-H2AX expression in peripheral blood lymphocytes from head and neck cancer patients with radiation-induced oral mucositis |
| Q35182983 | Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response |
| Q39210873 | DMAP1 is an essential regulator of ATM activity and function |
| Q38379038 | DNA damage foci: Meaning and significance. |
| Q54369251 | DNA double-strand break repair and induction of apoptosis in ex vivo irradiated blood lymphocytes in relation to late normal tissue reactions following breast radiotherapy. |
| Q46691963 | DNA double-strand break repair in parental chromatin of mouse zygotes, the first cell cycle as an origin of de novo mutation |
| Q37855947 | DNA double-strand break repair, immunodeficiency and the RIDDLE syndrome |
| Q36610563 | DNA repair capacity as a possible biomarker of breast cancer risk in female BRCA1 mutation carriers |
| Q40355869 | DNA repair foci and late apoptosis/necrosis in peripheral blood lymphocytes of breast cancer patients undergoing radiotherapy |
| Q27919702 | DNA-PK autophosphorylation facilitates Artemis endonuclease activity |
| Q34056301 | DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe |
| Q42007528 | DNA-PKcs and ATM co-regulate DNA double-strand break repair |
| Q41954597 | DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM). |
| Q39476754 | Defective DNA double-strand break repair in pediatric systemic lupus erythematosus |
| Q37822707 | Double-strand breaks and the concept of short- and long-term epigenetic memory. |
| Q35730250 | Drosophila ATR in double-strand break repair |
| Q91908367 | Dynamic modeling of cellular response to DNA damage based on p53 stress response networks |
| Q39626168 | Early Increase of Radiation-induced γH2AX Foci in a Human Ku70/80 Knockdown Cell Line Characterized by an Enhanced Radiosensitivity |
| Q33718637 | Effect of Ku70 expression on radiosensitivity in renal carcinoma 786-O cells |
| Q34333329 | Enhanced fidelity for rejoining radiation-induced DNA double-strand breaks in the G2 phase of Chinese hamster ovary cells |
| Q37597842 | Exploiting synthetic lethal interactions for targeted cancer therapy |
| Q42430226 | Gamma-H2AX foci in cells exposed to a mixed beam of X-rays and alpha particles |
| Q34038004 | Gamma-H2AX-based dose estimation for whole and partial body radiation exposure |
| Q37196316 | Genetic variations in DNA repair genes, radiosensitivity to cancer and susceptibility to acute tissue reactions in radiotherapy-treated cancer patients |
| Q36119310 | Global chromatin compaction limits the strength of the DNA damage response |
| Q33847860 | H2AX phosphorylation screen of cells from radiosensitive cancer patients reveals a novel DNA double-strand break repair cellular phenotype |
| Q39588354 | HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents |
| Q41838838 | HPV 5 and 8 E6 expression reduces ATM protein levels and attenuates LINE-1 retrotransposition. |
| Q35202869 | High throughput measurement of γH2AX DSB repair kinetics in a healthy human population |
| Q38036587 | Highly cited German research contributions to the fields of radiation oncology, biology, and physics: focus on collaboration and diversity |
| Q35611636 | Hyperthermia Induces Apoptosis of 786-O Cells through Suppressing Ku80 Expression |
| Q24529558 | In vivo formation and repair of DNA double-strand breaks after computed tomography examinations |
| Q34069451 | Inducible response required for repair of low-dose radiation damage in human fibroblasts |
| Q35661601 | Induction and Processing of the Radiation-Induced Gamma-H2AX Signal and Its Link to the Underlying Pattern of DSB: A Combined Experimental and Modelling Study. |
| Q40302698 | Induction and quantification of gamma-H2AX foci following low and high LET-irradiation |
| Q34157962 | Intraesophageal Manganese Superoxide Dismutase-Plasmid Liposomes Ameliorates Novel Total-Body and Thoracic Radiation Sensitivity of NOS1−/−Mice |
| Q33768588 | Ionizing radiation-dependent gamma-H2AX focus formation requires ataxia telangiectasia mutated and ataxia telangiectasia mutated and Rad3-related |
| Q40615400 | Isolation of chromatin from dysfunctional telomeres reveals an important role for Ring1b in NHEJ-mediated chromosome fusions |
| Q35900943 | JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells |
| Q39142926 | Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation |
| Q33282722 | Kinetics and dose-response of residual 53BP1/gamma-H2AX foci: co-localization, relationship with DSB repair and clonogenic survival |
| Q38550172 | Lack of a correlation between γH2AX foci kinetics in lymphocytes and the severity of acute normal tissue reactions during IMRT treatment for head and neck cancer |
| Q28387774 | Less efficient g2-m checkpoint is associated with an increased risk of lung cancer in African Americans |
| Q38821619 | Mechanistic Modelling of DNA Repair and Cellular Survival Following Radiation-Induced DNA Damage. |
| Q64098402 | Mechanistic modelling supports entwined rather than exclusively competitive DNA double-strand break repair pathway |
| Q35676592 | MicroR-545 enhanced radiosensitivity via suppressing Ku70 expression in Lewis lung carcinoma xenograft model |
| Q38068797 | MicroRNAs and DNA damage response: implications for cancer therapy. |
| Q31156407 | Microbial pathogens trigger host DNA double-strand breaks whose abundance is reduced by plant defense responses |
| Q30481837 | Microwaves from Mobile Phones Inhibit 53BP1 Focus Formation in Human Stem Cells More Strongly Than in Differentiated Cells: Possible Mechanistic Link to Cancer Risk |
| Q35860231 | Modeling DNA double-strand break repair kinetics as an epiregulated cell-community-wide (epicellcom) response to radiation stress |
| Q35092577 | Modeling damage complexity-dependent non-homologous end-joining repair pathway |
| Q64387978 | Modeling the interplay between DNA-PK, Artemis, and ATM in non-homologous end-joining repair in G1 phase of the cell cycle |
| Q36126009 | Molecular targets for tumor radiosensitization |
| Q34176919 | Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance |
| Q36499765 | Multiple functions of rad9 for preserving genomic integrity |
| Q37249487 | Normal Sequence and Activity but Reduced Levels of DNA-Pkcs in Human Lymphoblastic Cells Implicate Impaired Protein Stability with Radiosensitive Phenotype |
| Q36709924 | Novel connections between DNA replication, telomere homeostasis, and the DNA damage response revealed by a genome-wide screen for TEL1/ATM interactions in Saccharomyces cerevisiae |
| Q47281305 | Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair |
| Q39651756 | Over-expression of miR-100 is responsible for the low-expression of ATM in the human glioma cell line: M059J |
| Q37073602 | PKC signaling prevents irradiation-induced apoptosis of primary human fibroblasts |
| Q37977769 | PTEN in DNA damage repair |
| Q38608688 | Personalised Medicine: Genome Maintenance Lessons Learned from Studies in Yeast as a Model Organism |
| Q35891614 | Phosphorylation in the serine/threonine 2609-2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts |
| Q39126666 | Phosphorylation of Rad55 on serines 2, 8, and 14 is required for efficient homologous recombination in the recovery of stalled replication forks |
| Q33236676 | Phosphorylation of nucleotide excision repair factor xeroderma pigmentosum group A by ataxia telangiectasia mutated and Rad3-related-dependent checkpoint pathway promotes cell survival in response to UV irradiation |
| Q39007017 | Prediction of radiosensitivity using phosphorylation of histone H2AX and apoptosis in human tumor cell lines |
| Q39040990 | Quantitation of DNA double-strand break resection intermediates in human cells. |
| Q90439949 | Quantitative γ-H2AX immunofluorescence method for DNA double-strand break analysis in testis and liver after intravenous administration of 111InCl3 |
| Q33944173 | Radiation and ATM inhibition: the heart of the matter |
| Q36280683 | Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase |
| Q64101557 | Radiation: a poly-traumatic hit leading to multi-organ injury |
| Q36767034 | Radiosensitization by PARP Inhibition in DNA Repair Proficient and Deficient Tumor Cells: Proliferative Recovery in Senescent Cells |
| Q28262730 | Regulation of DNA double-strand break repair pathway choice |
| Q42717522 | Requirement of ATM-dependent pathway for the repair of a subset of DNA double strand breaks created by restriction endonucleases |
| Q42738049 | Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest |
| Q41336146 | Severe Late Toxicity After Adjuvant Breast Radiotherapy in a Patient with a Germline Ataxia Telangiectasia Mutated Gene: Future Treatment Decisions |
| Q28472717 | Shorter exposures to harder X-rays trigger early apoptotic events in Xenopus laevis embryos |
| Q39609112 | Sister chromatid exchanges occur in G2-irradiated cells |
| Q98771265 | Spontaneous and Radiation-Induced Chromosome Aberrations in Primary Fibroblasts of Patients With Pediatric First and Second Neoplasms |
| Q26822592 | Targeting ATM-deficient CLL through interference with DNA repair pathways |
| Q34352305 | The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain |
| Q39945725 | The DNA damage checkpoint pathways exert multiple controls on the efficiency and outcome of the repair of a double-stranded DNA gap. |
| Q28385968 | The HINT1 tumor suppressor regulates both gamma-H2AX and ATM in response to DNA damage |
| Q37722645 | The RABiT: high-throughput technology for assessing global DSB repair. |
| Q24794005 | The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cells |
| Q24605592 | The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage |
| Q28534631 | The efficiency of homologous recombination and non-homologous end joining systems in repairing double-strand breaks during cell cycle progression |
| Q34061457 | The human LINE-1 retrotransposon creates DNA double-strand breaks. |
| Q43178842 | The human set and transposase domain protein Metnase interacts with DNA Ligase IV and enhances the efficiency and accuracy of non-homologous end-joining |
| Q55044969 | The impact of a negligent G2/M checkpoint on genomic instability and cancer induction. |
| Q35849711 | The redox biology network in cancer pathophysiology and therapeutics |
| Q22122018 | The role of double-strand break repair — insights from human genetics |
| Q40219964 | The tandem BRCT domain of 53BP1 is not required for its repair function |
| Q41954705 | The use of caspase inhibitors in pulsed-field gel electrophoresis may improve the estimation of radiation-induced DNA repair and apoptosis. |
| Q43596090 | Variant ataxia telangiectasia: clinical and molecular findings and evaluation of radiosensitive phenotypes in a patient and relatives |
| Q24302150 | XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining |
| Q37549455 | p53 promotes repair of heterochromatin DNA by regulating JMJD2b and SUV39H1 expression |
| Q90226348 | γ-H2AX Foci Persistence at Chromosome Break Suggests Slow and Faithful Repair Phases Restoring Chromosome Integrity |
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