Ubiquitin-dependent regulation of G protein-coupled receptor trafficking and signaling

scientific article published on November 29, 2012

Ubiquitin-dependent regulation of G protein-coupled receptor trafficking and signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELLSIG.2012.11.024
P953full work available online athttps://api.elsevier.com/content/article/PII:S0898656812003270?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0898656812003270?httpAccept=text/xml
https://doi.org/10.1016/j.cellsig.2012.11.024
https://europepmc.org/articles/PMC3593103
https://europepmc.org/articles/pmc3593103?pdf=render
https://europepmc.org/articles/PMC3593103?pdf=render
P932PMC publication ID3593103
P698PubMed publication ID23201781

P50authorJoAnn TrejoQ61742920
P2093author name stringAdriano Marchese
P2860cites workApplied BioinformaticsQ15754366
Arrestins: ubiquitous regulators of cellular signaling pathwaysQ21184142
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The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activationQ50335944
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p300 Transcriptional Repression Is Mediated by SUMO ModificationQ60304936
The role of receptor kinases and arrestins in G protein-coupled receptor regulationQ74578170
Function of WW domains as phosphoserine- or phosphothreonine-binding modulesQ22008803
The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis toolsQ24248165
Involvement of chemokine receptors in breast cancer metastasisQ24290909
Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 buddingQ24291784
Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesisQ24293532
c-Cbl mediates ubiquitination, degradation, and down-regulation of human protease-activated receptor 2Q24294848
CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4Q24298867
VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargoQ24299091
The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4Q24299260
beta-Arrestin: a protein that regulates beta-adrenergic receptor functionQ24305145
The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H miceQ24308721
Ubiquitination of CXCR7 controls receptor traffickingQ24310278
Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativationQ24310461
The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interactionQ24312062
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligaseQ24313174
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomesQ24313594
Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2Q24315023
Involvement of linear polyubiquitylation of NEMO in NF-kappaB activationQ24315943
Role of mammalian vacuolar protein-sorting proteins in endocytic trafficking of a non-ubiquitinated G protein-coupled receptor to lysosomesQ24317093
Isoform-specific localization of the deubiquitinase USP33 to the Golgi apparatusQ24317741
ALIX binds a YPX3L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sortingQ24318395
LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMOQ24318791
Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptorQ24320318
The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitizationQ24323133
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activationQ24337851
Molecular genetic characterization of six recessive viable alleles of the mouse agouti locusQ24533165
An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexinsQ24541314
Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomesQ24548353
The Deubiquitinating Enzyme USP8 Promotes Trafficking and Degradation of the Chemokine Receptor 4 at the Sorting EndosomeQ24569667
The ESCRT complexesQ24569709
HECT and RING finger families of E3 ubiquitin ligases at a glanceQ24599672
Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffoldsQ24605173
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaksQ24608599
Agonist-promoted Lys63-linked polyubiquitination of the human kappa-opioid receptor is involved in receptor down-regulationQ24618315
AMSH interacts with ESCRT-0 to regulate the stability and trafficking of CXCR4Q24632729
ESCRT complexes and the biogenesis of multivesicular bodiesQ24646021
The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosisQ24651529
Ubiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomesQ24657919
The C2 domain of the Rsp5 ubiquitin ligase binds membrane phosphoinositides and directs ubiquitination of endosomal cargoQ24677536
Structural basis for viral late-domain binding to AlixQ27643742
Structural and functional studies of ALIX interactions with YPX(n)L late domains of HIV-1 and EIAVQ27649242
Hybrid Structural Model of the Complete Human ESCRT-0 ComplexQ27654065
Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activationQ27654230
The ubiquitin systemQ27860803
Membrane scission by the ESCRT-III complexQ27929846
Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular bodyQ27933819
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.Q27939053
Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface.Q27939550
Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sortingQ27939994
Regulation of monoubiquitinated PCNA by DUB autocleavageQ28115531
Drug discovery: a historical perspectiveQ28138834
Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestinQ28190513
AIP1/ALIX Is a Binding Partner for HIV-1 p6 and EIAV p9 Functioning in Virus BuddingQ28204548
WW and SH3 domains, two different scaffolds to recognize proline-rich ligandsQ28209648
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomesQ28211609
Modulation of postendocytic sorting of G protein-coupled receptorsQ28216085
Modification of proteins by ubiquitin and ubiquitin-like proteinsQ28244250
Regulation of receptor trafficking by GRKs and arrestinsQ28268248
Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptorQ34548751
β2-Adrenergic Receptor Lysosomal Trafficking Is Regulated by Ubiquitination of Lysyl Residues in Two Distinct Receptor DomainsQ34752710
Membrane buddingQ35007633
β-arrestin-mediated receptor trafficking and signal transductionQ35175384
Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation.Q35213193
Ubiquitination in the First Cytoplasmic Loop of μ-Opioid Receptors Reveals a Hierarchical Mechanism of Lysosomal Down-regulationQ35562807
Arrestin development: emerging roles for beta-arrestins in developmental signaling pathwaysQ35565885
The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architectureQ35691527
Molecular Mechanisms of Ubiquitin-Dependent Membrane TrafficQ35738601
Ubiquitination differentially regulates clathrin-dependent internalization of protease-activated receptor-1Q36118471
AP-3 regulates PAR1 ubiquitin-independent MVB/lysosomal sorting via an ALIX-mediated pathway.Q36234486
Morphine-activated opioid receptors elude desensitization by β-arrestinQ36280218
Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalizationQ36289141
Regulation of endocytic clathrin dynamics by cargo ubiquitinationQ36315903
Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activationQ36411260
Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsivenessQ36514037
Ubiquitin and ubiquitin-like proteins in cancer pathogenesisQ36601000
Role of ubiquitin- and Ubl-binding proteins in cell signalingQ36736630
Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptorsQ36773326
Seven transmembrane receptors: something old, something new.Q36788556
Termination of signaling by protease-activated receptor-1 is linked to lysosomal sortingQ36796521
The spatial and temporal organization of ubiquitin networksQ36844591
The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptorQ36915326
Heterotrimeric G protein activation by G-protein-coupled receptorsQ37017125
The type I TGF-beta receptor is covalently modified and regulated by sumoylationQ37112272
Endosomal deubiquitinating enzymes control ubiquitination and down-regulation of protease-activated receptor 2.Q37460026
Ubiquitin and membrane protein turnover: from cradle to graveQ37992157
Arrestin domain-containing protein 3 recruits the NEDD4 E3 ligase to mediate ubiquitination of the beta2-adrenergic receptor.Q39691240
The carboxyl-terminal PDZ ligand motif of chemokine receptor CXCR2 modulates post-endocytic sorting and cellular chemotaxisQ39945961
Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4.Q40065770
Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) mediates post-endocytic trafficking of protease-activated receptor 2 and calcitonin receptor-like receptorQ40098284
Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestinsQ40175757
Receptor-specific ubiquitination of beta-arrestin directs assembly and targeting of seven-transmembrane receptor signalosomes.Q40460839
Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitinationQ40672031
Agonist-promoted Ubiquitination of the G Protein-coupled Receptor CXCR4 Mediates Lysosomal SortingQ40773765
The cytoplasmic tails of protease-activated receptor-1 and substance P receptor specify sorting to lysosomes versus recyclingQ40980278
Type-specific sorting of G protein-coupled receptors after endocytosisQ41728938
Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.Q42823593
Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosisQ43610822
The Cbl interactome and its functionsQ28277251
A genomic and functional inventory of deubiquitinating enzymesQ28284911
Mechanism and function of deubiquitinating enzymesQ28295758
Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestinsQ28578546
Pias1 interaction and sumoylation of metabotropic glutamate receptor 8Q28581086
On the origins of arrestin and rhodopsinQ28757417
The druggable genomeQ29547361
Protein modification by SUMOQ29547919
Ubiquitin-binding domainsQ29614358
Ubiquitin-binding domains - from structures to functionsQ29614829
Ubiquitin-binding domainsQ29616461
Ubiquitin: structures, functions, mechanismsQ29616462
Beta-arrestins and cell signalingQ29616793
Physiological functions of the HECT family of ubiquitin ligasesQ29617293
Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosisQ29617390
The nuts and bolts of AGC protein kinasesQ29617465
Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptorQ29618735
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomesQ29619337
The ESCRT PathwayQ29620052
The biogenesis of multivesicular endosomesQ29620561
Vps27 recruits ESCRT machinery to endosomes during MVB sortingQ29620778
Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling.Q30010172
Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signalingQ30432989
The role of ubiquitination in lysosomal trafficking of δ-opioid receptorsQ30499514
Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomesQ31048369
Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosisQ33285633
Molecular bases for the recognition of tyrosine-based sorting signalsQ33648614
G protein-coupled receptor sorting to endosomes and lysosomesQ33848408
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4Q33992591
Cbl: many adaptations to regulate protein tyrosine kinasesQ34205572
A map of WW domain family interactionsQ34302785
International Union of Pharmacology. XLVI. G protein-coupled receptor list.Q34421152
Identification of a novel sequence mediating regulated endocytosis of the G protein-coupled alpha-pheromone receptor in yeastQ34436938
Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.Q34536660
Small Ubiquitin-like Modifier Modification of Arrestin-3 Regulates Receptor TraffickingQ34537060
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectG protein-coupled receptorQ38173
P1104number of pages10
P304page(s)707-716
P577publication date2012-11-29
P13046publication type of scholarly workreview articleQ7318358
P1433published inCellular SignallingQ1524097
P1476titleUbiquitin-dependent regulation of G protein-coupled receptor trafficking and signaling
P478volume25

Reverse relations

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