The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4

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The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4 is …
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scholarly articleQ13442814

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P356DOI10.1016/S1534-5807(03)00321-6
P3181OpenCitations bibliographic resource ID732424
P698PubMed publication ID14602072

P50authorHarald StenmarkQ17109045
P2093author name stringCamilla Raiborg
Adriano Marchese
Jeffrey L Benovic
Francesca Santini
James H Keen
P2860cites workFunction of WW domains as phosphoserine- or phosphothreonine-binding modulesQ22008803
TSG101/mammalian VPS23 and mammalian VPS28 interact directly and are recruited to VPS4-induced endosomesQ24290676
Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugatesQ24292701
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomesQ24313594
Syntaxin-16, a putative Golgi t-SNAREQ24316198
Identification of novel human WW domain-containing proteins by cloning of ligand targetsQ24336090
Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinasesQ24515076
The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome functionQ24533245
Hrs recruits clathrin to early endosomesQ24535764
Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular bodyQ27933819
The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathwaysQ27936688
Domains of the Rsp5 ubiquitin-protein ligase required for receptor-mediated and fluid-phase endocytosisQ27936947
The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting.Q27937143
Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4pQ27938642
Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targetingQ27938877
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.Q27939053
Receptor downregulation and multivesicular-body sortingQ28131720
A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKPQ28138440
Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestinQ28190513
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomesQ28205230
A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteinsQ29616733
Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosisQ29617390
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosisQ29618143
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomesQ29619337
Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomesQ31048369
Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.Q31109069
Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosisQ33285633
Ligand-independent degradation of epidermal growth factor receptor involves receptor ubiquitylation and Hgs, an adaptor whose ubiquitin-interacting motif targets ubiquitylation by Nedd4.Q33292150
Localization of the Rsp5p ubiquitin-protein ligase at multiple sites within the endocytic pathwayQ33559052
Nedd4-like proteins: an emerging family of ubiquitin-protein ligases implicated in diverse cellular functionsQ33632965
Cbl: many adaptations to regulate protein tyrosine kinasesQ34205572
Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteinsQ34568617
The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cellsQ34687885
The ins and outs of G protein-coupled receptor traffickingQ35183866
Ubiquitination of the yeast a-factor receptorQ36237205
Clathrin assembly protein AP-2 induces aggregation of membrane vesicles: a possible role for AP-2 in endosome formationQ36532205
Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sortingQ40773765
100-kD coated vesicle proteins: molecular heterogeneity and intracellular distribution studied with monoclonal antibodiesQ41514832
Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosisQ43610822
Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in DrosophilaQ43879100
Ubiquitin Sorts Proteins into the Intralumenal Degradative Compartment of the Late-Endosome/VacuoleQ58480871
Regulation of human chemokine receptors CXCR4. Role of phosphorylation in desensitization and internalizationQ73836239
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectprotein ubiquitinationQ3547638
G protein-coupled receptorQ38173
Itchy E3 ubiquitin protein ligaseQ21109507
P304page(s)709-22
P577publication date2003-11-01
P1433published inDevelopmental CellQ1524277
P1476titleThe E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
P478volume5

Reverse relations

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