A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT ubiquitination

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A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT ubiquitination is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.201008121
P932PMC publication ID3172180
P698PubMed publication ID21242292
P5875ResearchGate publication ID49762444

P50authorRobert C. PiperQ55179944
P2093author name stringDaniel K Stringer
P2860cites workDistinct functions of human MVB12A and MVB12B in the ESCRT-I dependent on their posttranslational modificationsQ24292913
Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal traffickingQ24293322
VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargoQ24299091
The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4Q24299260
Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus buddingQ24299456
The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulationQ24306674
Interactions of GGA3 with the ubiquitin sorting machineryQ24319723
Two-sided ubiquitin binding explains specificity of the TAB2 NZF domainQ24320937
Biogenesis and function of multivesicular bodiesQ24601502
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymesQ24645701
AMSH is an endosome-associated ubiquitin isopeptidaseQ24676880
Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3Q24683139
Structure of a herpesvirus-encoded cysteine protease reveals a unique class of deubiquitinating enzymesQ27644017
Functional profiling of the Saccharomyces cerevisiae genomeQ27860544
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiaeQ27860636
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysisQ27860815
Gga2 mediates sequential ubiquitin-independent and ubiquitin-dependent steps in the trafficking of ARN1 from the trans-Golgi network to the vacuole.Q27929961
Production of a functional eukaryotic enzyme in Escherichia coli: cloning and expression of the yeast structural gene for imidazole-glycerolphosphate dehydratase (his3)Q27931182
The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants.Q27931357
The F-box protein Rcy1p is involved in endocytic membrane traffic and recycling out of an early endosome in Saccharomyces cerevisiaeQ27931511
Skp1p and the F-box protein Rcy1p form a non-SCF complex involved in recycling of the SNARE Snc1p in yeastQ27931687
Functional domains of the Rsp5 ubiquitin-protein ligase.Q27931992
ESCRT ubiquitin-binding domains function cooperatively during MVB cargo sortingQ27931999
The membrane proteins, Spt23p and Mga2p, play distinct roles in the activation of Saccharomyces cerevisiae OLE1 gene expression. Fatty acid-mediated regulation of Mga2p activity is independent of its proteolytic processing into a soluble transcriptioQ27932612
The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzymeQ27933628
GGA proteins bind ubiquitin to facilitate sorting at the trans-Golgi networkQ27934125
DOA1/UFD3 plays a role in sorting ubiquitinated membrane proteins into multivesicular bodiesQ27934992
Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12Q27936850
Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutantsQ27936883
Domains of the Rsp5 ubiquitin-protein ligase required for receptor-mediated and fluid-phase endocytosisQ27936947
The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting.Q27937143
Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing.Q27937925
Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4pQ27938642
Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targetingQ27938877
Regulation of monoubiquitinated PCNA by DUB autocleavageQ28115531
Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applicationsQ28131600
A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettesQ28131622
A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKPQ28138440
Ubiquitin-binding domainsQ29614358
A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteinsQ29616733
A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeastQ29616852
Physiological functions of the HECT family of ubiquitin ligasesQ29617293
The emerging shape of the ESCRT machineryQ29620787
Hse1, a component of the yeast Hrs-STAM ubiquitin-sorting complex, associates with ubiquitin peptidases and a ligase to control sorting efficiency into multivesicular bodiesQ30159582
A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family HerpesviridaeQ31000683
Ligand-independent degradation of epidermal growth factor receptor involves receptor ubiquitylation and Hgs, an adaptor whose ubiquitin-interacting motif targets ubiquitylation by Nedd4.Q33292150
The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognitionQ33412039
The function of yeast epsin and Ede1 ubiquitin-binding domains during receptor internalizationQ33957071
The GAT domains of clathrin-associated GGA proteins have two ubiquitin binding motifsQ34026517
Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligaseQ34430908
Yeast P4-ATPases Drs2p and Dnf1p are essential cargos of the NPFXD/Sla1p endocytic pathway.Q35613387
Direct sorting of the yeast uracil permease to the endosomal system is controlled by uracil binding and Rsp5p-dependent ubiquitylation.Q35803062
The Hrs/STAM complex in the downregulation of receptor tyrosine kinasesQ36043224
A functional ubiquitin-specific protease embedded in the large tegument protein (ORF64) of murine gammaherpesvirus 68 is active during the course of infectionQ36099153
Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sortingQ36219420
Specific sterols required for the internalization step of endocytosis in yeastQ36940667
Polyubiquitination by HECT E3s and the determinants of chain type specificityQ37233382
K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathwayQ37237626
Cleavage specificity of the UL48 deubiquitinating protease activity of human cytomegalovirus and the growth of an active-site mutant virus in cultured cellsQ37452085
The ubiquitin code of yeast permease trafficking.Q37688555
ESCRT & Co.Q37707470
A ubiquitin mutant with specific defects in DNA repair and multiubiquitinationQ40015739
Analysis of the role of ubiquitin-interacting motifs in ubiquitin binding and ubiquitylationQ40553487
Glucose-induced ubiquitylation and endocytosis of the yeast Jen1 transporter: role of lysine 63-linked ubiquitin chainsQ42550191
Arrestin-mediated endocytosis of yeast plasma membrane transportersQ42931930
Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cellsQ45823697
Substrate- and ubiquitin-dependent trafficking of the yeast siderophore transporter Sit1.Q50634581
E3-independent monoubiquitination of ubiquitin-binding proteins.Q55044113
Working out coupled monoubiquitinationQ57912462
Molecular mechanisms of coupled monoubiquitinationQ57964128
Ubiquitin Sorts Proteins into the Intralumenal Degradative Compartment of the Late-Endosome/VacuoleQ58480871
The deubiquitinating enzyme Ubp2 modulates Rsp5-dependent Lys63-linked polyubiquitin conjugates in Saccharomyces cerevisiaeQ79209223
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectprotein ubiquitinationQ3547638
P304page(s)229-242
P577publication date2011-01-17
P1433published inJournal of Cell BiologyQ1524550
P1476titleA single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT ubiquitination
P478volume192

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cites work (P2860)
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Q36462343α-Arrestins participate in cargo selection for both clathrin-independent and clathrin-mediated endocytosis

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