The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function

scientific article published on June 1, 1998

The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/EMBOJ/17.11.2982
P953full work available at URLhttp://emboj.embopress.org/content/17/11/2982.full.pdf
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1093%2Femboj%2F17.11.2982
https://doi.org/10.1093/emboj/17.11.2982
https://europepmc.org/articles/PMC1170638
https://europepmc.org/articles/PMC1170638?pdf=render
https://onlinelibrary.wiley.com/doi/full/10.1093/emboj/17.11.2982
P3181OpenCitations bibliographic resource ID822617
P932PMC publication ID1170638
P698PubMed publication ID9606181
P5875ResearchGate publication ID13678403

P2093author name stringM. Babst
S. D. Emr
B. Wendland
E. J. Estepa
P2860cites workTransformation of intact yeast cells treated with alkali cationsQ24672708
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Dynamin self-assembly stimulates its GTPase activityQ41168345
SNAREs and NSF in targeted membrane fusionQ41566661
Sequence analysis of the AAA protein familyQ41615832
Evidence for ADP-ribosylation factor (ARF) as a regulator of in vitro endosome-endosome fusion.Q41618601
Domain structure and intramolecular regulation of dynamin GTPaseQ42094777
The VPS16 gene product associates with a sedimentable protein complex and is essential for vacuolar protein sorting in yeastQ42620026
Vesicular transport between the endoplasmic reticulum and the Golgi stack requires the NEM-sensitive fusion protein.Q46006227
Rab7 regulates transport from early to late endocytic compartments in Xenopus oocytesQ48957968
Photoaffinity labeling of the cap-binding protein complex with ATP/dATP. Differential labeling of free eukaryotic initiation factor 4A and the eukaryotic initiation factor 4A component of the cap-binding protein complex with [alpha-32P]ATP/dATP.Q53841119
Each Domain of theN-Ethylmaleimide-sensitive Fusion Protein Contributes to Its Transport ActivityQ58413637
GTPase activity of Rab5 acts as a timer for endocytic membrane fusionQ59097967
Cytoplasmic coat proteins involved in endosome functionQ70787141
Regulatory role of major tyrosine autophosphorylation site of kinase domain of c-Met receptor (scatter factor/hepatocyte growth factor receptor)Q71626932
Predicting coiled coils from protein sequencesQ27861097
The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondriaQ27931009
The ATPase activity of purified CDC48p from Saccharomyces cerevisiae shows complex dependence on ATP-, ADP-, and NADH-concentrations and is completely inhibited by NEM.Q27931559
Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutantQ27932509
Transport through the yeast endocytic pathway occurs through morphologically distinct compartments and requires an active secretory pathway and Sec18p/N-ethylmaleimide-sensitive fusion proteinQ27934568
A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteinsQ27936114
Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutantsQ27936883
Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeastQ27937502
Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolasesQ27937990
Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4pQ27938642
The VPS4 gene is involved in protein transport out of a yeast pre-vacuolar endosome-like compartmentQ27939419
Multifunctional yeast high-copy-number shuttle vectorsQ28131605
Hrs, a Tyrosine Kinase Substrate with a Conserved Double Zinc Finger Domain, Is Localized to the Cytoplasmic Surface of Early EndosomesQ28245945
Identification of a novel mammalian member of the NSF/CDC48p/Pas1p/TBP-1 family through heterologous expression in yeastQ28247881
A 200‐amino acid ATPase module in search of a basic functionQ28295702
Syntaxin 6 functions in trans-Golgi network vesicle traffickingQ28572919
Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopyQ28581498
Membrane transport in the endocytic pathwayQ29616400
Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutantQ29619309
The synaptic vesicle cycle: a cascade of protein-protein interactionsQ29620168
Tubular membrane invaginations coated by dynamin rings are induced by GTP-gamma S in nerve terminalsQ29620183
VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiaeQ29620184
The diversity of Rab proteins in vesicle transportQ29620216
Proteinase mutants of Saccharomyces cerevisiaeQ29622915
The AAA team: related ATPases with diverse functionsQ32042429
Mutational analysis of Csc1/Vps4p: involvement of endosome in regulation of autophagy in yeastQ32144289
Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiaeQ33569803
An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF.Q33920064
Molecular and genetic analysis of the SNF7 gene in Saccharomyces cerevisiaeQ33961527
The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localizationQ34451174
A novel Sec18p/NSF-dependent complex required for Golgi-to-endosome transport in yeastQ34671002
Assembly of the mitochondrial membrane system. CBP6, a yeast nuclear gene necessary for synthesis of cytochrome b.Q36422894
Multiple N-ethylmaleimide-sensitive components are required for endosomal vesicle fusionQ40366194
Inhibition of Endosome Function in CHO Cells Bearing a Temperature-sensitive Defect in the Coatomer (COPI) Component ε-COPQ41067848
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectnuclear proteinQ16860021
ATPase complexQ24570646
ESCRT-III subunit protein VPS24 YKL041WQ27547505
Saccharomyces cerevisiae proteinsQ65969294
AAA family ATPase VPS4 YPR173CQ27548987
ESCRT-III subunit protein SNF7 YLR025WQ27551446
P304page(s)2982-93
P577publication date1998-06-01
P1433published inThe EMBO JournalQ1278554
P1476titleThe Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function
P478volume17

Reverse relations

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Q36159368Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae
Q30656507Molecular snapshots of the Pex1/6 AAA+ complex in action
Q36791778More than one door - Budding of enveloped viruses through cellular membranes
Q34742425Multiple interactions between the ESCRT machinery and arrestin-related proteins: implications for PPXY-dependent budding.
Q34663489Multivesicular bodies in neurons: Distribution, protein content, and trafficking functions
Q39843842Multivesicular endosome biogenesis in the absence of ESCRTs
Q52545437Mutants defective in secretory/vacuolar pathways in the EUROFAN collection of yeast disruptants
Q33752602Mutational analysis of Candida albicans SNF7 reveals genetically separable Rim101 and ESCRT functions and demonstrates divergence in bro1-domain protein interactions
Q33749062Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS).
Q24309521Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia
Q37479874NMR studies on the interactions between yeast Vta1 and Did2 during the multivesicular bodies sorting pathway
Q27934114New component of ESCRT-I regulates endosomal sorting complex assembly
Q24655056No strings attached: the ESCRT machinery in viral budding and cytokinesis
Q27935558Novel Ist1-Did2 complex functions at a late step in multivesicular body sorting
Q24316382Novel interactions of ESCRT-III with LIP5 and VPS4 and their implications for ESCRT-III disassembly
Q27932180Ordering of compartments in the yeast endocytic pathway
Q24541306Overlapping motifs (PTAP and PPEY) within the Ebola virus VP40 protein function independently as late budding domains: involvement of host proteins TSG101 and VPS-4.
Q40706177PIKfyve Kinase and SKD1 AAA ATPase define distinct endocytic compartments. Only PIKfyve expression inhibits the cell-vacoulating activity of Helicobacter pylori VacA toxin
Q41937369PalC, one of two Bro1 domain proteins in the fungal pH signalling pathway, localizes to cortical structures and binds Vps32.
Q33935172Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking
Q27933496Permease Recycling and Ubiquitination Status Reveal a Particular Role for Bro1 in the Multivesicular Body Pathway
Q36950740Pex17p is required for import of both peroxisome membrane and lumenal proteins and interacts with Pex19p and the peroxisome targeting signal-receptor docking complex in Pichia pastoris
Q36876929Pex19p interacts with Pex3p and Pex10p and is essential for peroxisome biogenesis in Pichia pastoris
Q27935751Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membrane
Q27939486Phosphatidylethanolamine, a limiting factor of autophagy in yeast strains bearing a defect in the carboxypeptidase Y pathway of vacuolar targeting
Q47162529Physical, Functional and Genetic Interactions between the BEACH Domain Protein SPIRRIG and LIP5 and SKD1 and Its Role in Endosomal Trafficking to the Vacuole in Arabidopsis
Q43182543Physiological involvement in pH signaling of Vps24-mediated recruitment of Aspergillus PalB cysteine protease to ESCRT-III.
Q24307470Plasma membrane deformation by circular arrays of ESCRT-III protein filaments
Q38131893Plasma membrane protein ubiquitylation and degradation as determinants of positional growth in plants
Q37629486Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse
Q82533380Polycistronic expression and purification of the ESCRT-II endosomal trafficking complex
Q27929881Post-Golgi Sec proteins are required for autophagy in Saccharomyces cerevisiae
Q40241807Potent inhibition of human Hepatitis B virus replication by a host factor Vps4.
Q24683048Potent rescue of human immunodeficiency virus type 1 late domain mutants by ALIX/AIP1 depends on its CHMP4 binding site
Q43544080Probing the mechanism of ATP hydrolysis and substrate translocation in the AAA protease FtsH by modelling and mutagenesis
Q57179714Protein traffic in the yeast endocytic and vacuolar protein sorting pathways
Q27935665Protein-protein interactions of ESCRT complexes in the yeast Saccharomyces cerevisiae.
Q42174778Protein–Protein Interaction Network and Subcellular Localization of the Arabidopsis Thaliana ESCRT Machinery
Q33381218Proteomic analysis of secreted membrane vesicles of archaeal Sulfolobus species reveals the presence of endosome sorting complex components
Q36749625Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy
Q38023421Quantitative live-cell imaging of human immunodeficiency virus (HIV-1) assembly.
Q28131720Receptor downregulation and multivesicular-body sorting
Q24300949Recognition of C-terminal amino acids in tubulin by pore loops in Spastin is important for microtubule severing
Q43258934Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding
Q45399133Recruitment of Alix/AIP1 to the plasma membrane by Sendai virus C protein facilitates budding of virus-like particles
Q24683826Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1
Q24515262Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member.
Q40998372Regulation of Membrane Protein Degradation by Starvation‐Response Pathways
Q42703646Regulation of Rab5 isoforms by transcriptional and post-transcriptional mechanisms in yeast
Q24303431Regulation of Tsg101 expression by the steadiness box: a role of Tsg101-associated ligase
Q37368267Regulation of Vps4 ATPase activity by ESCRT-III.
Q24597050Regulation of Vps4 During MVB Sorting and Cytokinesis
Q24533246Regulation of gene expression by ambient pH in filamentous fungi and yeasts
Q41456400Regulation of ribulose-1,5-bisphosphate carboxylase/oxygenase (rubisco) activase: product inhibition, cooperativity, and magnesium activation
Q37669957Regulation of yeast ESCRT-III membrane scission activity by the Doa4 ubiquitin hydrolase
Q30493608Regulators of Vps4 ATPase activity at endosomes differentially influence the size and rate of formation of intralumenal vesicles
Q22001542Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA
Q24677985Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding
Q37151081Relief of Autoinhibition Enhances Vta1 Activation of Vps4 via the Vps4 Stimulatory Element
Q46734988Requirements for ATP binding and hydrolysis in RecA function in Escherichia coli
Q37892093Requirements for the catalytic cycle of the N-ethylmaleimide-Sensitive Factor (NSF).
Q39970278Rescue of Aspergillus nidulans severely debilitating null mutations in ESCRT-0, I, II and III genes by inactivation of a salt-tolerance pathway allows examination of ESCRT gene roles in pH signalling
Q37543507Reverse-topology membrane scission by the ESCRT proteins
Q24316325RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport
Q24554467Role of ESCRT-I in retroviral budding
Q24317093Role of mammalian vacuolar protein-sorting proteins in endocytic trafficking of a non-ubiquitinated G protein-coupled receptor to lysosomes
Q30483185Role of nucleotide binding in septin-septin interactions and septin localization in Saccharomyces cerevisiae
Q36574671Roles of septins in prospore membrane morphogenesis and spore wall assembly in Saccharomyces cerevisiae
Q28205230STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
Q36313757Schizosaccharomyces pombe Sst4p, a conserved Vps27/Hrs homolog, functions downstream of phosphatidylinositol 3-kinase Pik3p to mediate proper spore formation
Q42070695Seeds of Arabidopsis plants expressing dominant-negative AtSKD1 under control of the GL2 promoter show a transparent testa phenotype and a mucilage defect
Q45404583Sendai virus budding in the course of an infection does not require Alix and VPS4A host factors
Q54448078Sensor I threonine of the AAA+ ATPase transcriptional activator PspF is involved in coupling nucleotide triphosphate hydrolysis to the restructuring of sigma 54-RNA polymerase.
Q37970884Shaping development with ESCRTs
Q40842252Significantly Diverged Did2/Vps46 Orthologues from the Protozoan Parasite Giardia lamblia
Q27932895Sna3 is an Rsp5 adaptor protein that relies on ubiquitination for its MVB sorting
Q38333304Snf7p, a component of the ESCRT-III protein complex, is an upstream member of the RIM101 pathway in Candida albicans
Q33954578Sorting in the endosomal system in yeast and animal cells.
Q35106286Stable isotope labeling with amino acids in cell culture based mass spectrometry approach to detect transient protein interactions using substrate trapping
Q27671639Structural Basis for ESCRT-III CHMP3 Recruitment of AMSH
Q27655663Structural Basis of Ist1 Function and Ist1-Did2 Interaction in the Multivesicular Body Pathway and Cytokinesis
Q27674772Structural Basis of Molecular Recognition between ESCRT-III-like Protein Vps60 and AAA-ATPase Regulator Vta1 in the Multivesicular Body Pathway
Q27649536Structural Basis of Vta1 Function in the Multivesicular Body Sorting Pathway
Q27648853Structural Characterization of the ATPase Reaction Cycle of Endosomal AAA Protein Vps4
Q27664001Structural Role of the Vps4-Vta1 Interface in ESCRT-III Recycling
Q27715381Structural and functional characterization of the microtubule interacting and trafficking domains of two oomycete chitin synthases
Q24337258Structural and mechanistic studies of VPS4 proteins
Q24318322Structural basis for autoinhibition of ESCRT-III CHMP3
Q24338462Structural basis for budding by the ESCRT-III factor CHMP3
Q88645890Structural basis for disassembly of katanin heterododecamers
Q27667588Structural basis for endosomal recruitment of ESCRT-I by ESCRT-0 in yeast
Q27934466Structural basis for endosomal targeting by the Bro1 domain
Q27648751Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4
Q24328880Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A.
Q27657043Structure and Function of the ESCRT-II-III Interface in Multivesicular Body Biogenesis
Q27640720Structure and Ubiquitin Interactions of the Conserved Zinc Finger Domain of Npl4
Q24530646Structure and function of human Vps20 and Snf7 proteins
Q37916764Structure and function of the AAA+ nucleotide binding pocket
Q37933868Structure and function of the membrane deformation AAA ATPase Vps4
Q64231635Structure and mechanism of the ESCRT pathway AAA+ ATPase Vps4
Q24298497Structure of cellular ESCRT-III spirals and their relationship to HIV budding
Q27934252Structure of the ESCRT-II endosomal trafficking complex
Q36845333Suppressor of K+ transport growth defect 1 (SKD1) interacts with RING-type ubiquitin ligase and sucrose non-fermenting 1-related protein kinase (SnRK1) in the halophyte ice plant
Q27937027Surveillance of nuclear pore complex assembly by ESCRT-III/Vps4.
Q24290676TSG101/mammalian VPS23 and mammalian VPS28 interact directly and are recruited to VPS4-induced endosomes
Q30159469Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation
Q46328475The AAA ATPase VPS4/SKD1 regulates endosomal cholesterol trafficking independently of ESCRT-III.
Q40175556The AAA ATPase Vps4 Plays Important Roles in Candida albicans Hyphal Formation and is Inhibited by DBeQ.
Q33769230The AAA+ ATPase ATAD3A controls mitochondrial dynamics at the interface of the inner and outer membranes.
Q24308624The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting
Q42511949The Arabidopsis AAA ATPase SKD1 is involved in multivesicular endosome function and interacts with its positive regulator LYST-INTERACTING PROTEIN5.
Q83730478The Arabidopsis ESCRT protein–protein interaction network
Q48309831The Arabidopsis Endosomal Sorting Complex Required for Transport III Regulates Internal Vesicle Formation of the Prevacuolar Compartment and Is Required for Plant Development.
Q36952408The Arabidopsis LYST INTERACTING PROTEIN 5 Acts in Regulating Abscisic Acid Signaling and Drought Response
Q30010261The Arabidopsis deubiquitinating enzyme AMSH3 interacts with ESCRT-III subunits and regulates their localization
Q34334009The Arf-GTPase-activating protein Gcs1p is essential for sporulation and regulates the phospholipase D Spo14p
Q33556224The BiP molecular chaperone plays multiple roles during the biogenesis of torsinA, an AAA+ ATPase associated with the neurological disease early-onset torsion dystonia
Q36609091The Bro1-related protein HD-PTP/PTPN23 is required for endosomal cargo sorting and multivesicular body morphogenesis
Q35784883The C-terminal portion of the Hrs protein interacts with Tsg101 and interferes with human immunodeficiency virus type 1 Gag particle production
Q24677536The C2 domain of the Rsp5 ubiquitin ligase binds membrane phosphoinositides and directs ubiquitination of endosomal cargo
Q34055196The Candida albicans ESCRT pathway makes Rim101-dependent and -independent contributions to pathogenesis
Q52353559The Conserved ESCRT-III Machinery Participates in the Phagocytosis of Entamoeba histolytica
Q27936688The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways
Q36902677The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast
Q39206028The Drosophila Chmp1 protein determines wing cell fate through regulation of epidermal growth factor receptor signaling
Q24299260The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
Q29620052The ESCRT Pathway
Q24683234The ESCRT complexes: structure and mechanism of a membrane-trafficking network
Q53286462The ESCRT machinery: a cellular apparatus for sorting and scission
Q26849199The ESCRT machinery: from the plasma membrane to endosomes and back again
Q48181638The ESCRT protein Chmp4c regulates mitotic spindle checkpoint signaling.
Q33815533The ESCRT-0 component HRS is required for HIV-1 Vpu-mediated BST-2/tetherin down-regulation
Q27939980The ESCRT-III adaptor protein Bro1 controls functions of regulator for free ubiquitin chains 1 (Rfu1) in ubiquitin homeostasis
Q47069579The ESCRT-III protein CeVPS-32 is enriched in domains distinct from CeVPS-27 and CeVPS-23 at the endosomal membrane of epithelial cells
Q24596374The ESCRT-associated protein Alix recruits the ubiquitin ligase Nedd4-1 to facilitate HIV-1 release through the LYPXnL L domain motif
Q51755862The ESCRT-related CHMP1A and B proteins mediate multivesicular body sorting of auxin carriers in Arabidopsis and are required for plant development
Q99556911The ESCRTs - converging on mechanism
Q27932956The Endosomal Sorting Complex ESCRT-II Mediates the Assembly and Architecture of ESCRT-III Helices
Q37168459The Linker Region Plays a Regulatory Role in Assembly and Activity of the Vps4 AAA ATPase
Q24337922The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation
Q34874464The Maize AAA-Type Protein SKD1 Confers Enhanced Salt and Drought Stress Tolerance in Transgenic Tobacco by Interacting with Lyst-Interacting Protein 5
Q27309437The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling
Q36130065The Multivesicular Bodies (MVBs)-Localized AAA ATPase LRD6-6 Inhibits Immunity and Cell Death Likely through Regulating MVBs-Mediated Vesicular Trafficking in Rice
Q27680464The Oligomeric State of the Active Vps4 AAA ATPase
Q89896520The Role of Secretory Pathways in Candida albicans Pathogenesis
Q27938195The Vps4 C-terminal helix is a critical determinant for assembly and ATPase activity and has elements conserved in other members of the meiotic clade of AAA ATPases
Q41378209The Xanthomonas campestris type III effector XopJ proteolytically degrades proteasome subunit RPT6.
Q40196906The YLDL sequence within Sendai virus M protein is critical for budding of virus-like particles and interacts with Alix/AIP1 independently of C protein
Q34428283The Zebrafish Homologue of the Human DYT1 Dystonia Gene Is Widely Expressed in CNS Neurons but Non-Essential for Early Motor System Development
Q42958044The allosteric role of the AAA+ domain of ChlD protein from the magnesium chelatase of synechocystis species PCC 6803.
Q92622339The auxiliary ESCRT complexes provide robustness to cold in poikilothermic organisms
Q34248085The complex ultrastructure of the endolysosomal system.
Q33638393The complexity of vesicle transport factors in plants examined by orthology search.
Q40429659The coordinated action of the MVB pathway and autophagy ensures cell survival during starvation
Q36022207The coordination of cyclic microtubule association/dissociation and tail swing of cytoplasmic dynein
Q29620787The emerging shape of the ESCRT machinery
Q48019408The extracellular role of DNA damage repair protein APE1 in regulation of IL-6 expression
Q24297840The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding
Q58629086The lysosomal trafficking regulator interacting protein-5 localizes mainly in epithelial cells.
Q91199451The many functions of ESCRTs
Q30496904The microtubule plus-end localization of Aspergillus dynein is important for dynein-early-endosome interaction but not for dynein ATPase activation.
Q34687885The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cells
Q33417652The nucleocapsid region of HIV-1 Gag cooperates with the PTAP and LYPXnL late domains to recruit the cellular machinery necessary for viral budding
Q24537160The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B
Q33785021The proteasome: a macromolecular assembly designed for controlled proteolysis
Q35215342The protein transportation pathway from Golgi to vacuoles via endosomes plays a role in enhancement of methylmercury toxicity.
Q36098938The role of WWP1-Gag interaction and Gag ubiquitination in assembly and release of human T-cell leukemia virus type 1
Q37026739The role of exosomes in the processing of proteins associated with neurodegenerative diseases
Q28251994The role of the VPS4A-exosome pathway in the intrinsic egress route of a DNA-binding anticancer drug
Q36889025The role of ubiquitin in retroviral egress
Q43258170The secreted Salmonella dublin phosphoinositide phosphatase, SopB, localizes to PtdIns(3)P-containing endosomes and perturbs normal endosome to lysosome trafficking
Q35625707The secretory system of Arabidopsis.
Q37987600The signaling mechanism of ambient pH sensing and adaptation in yeast and fungi
Q34784061The sodium/proton exchanger Nhx1p is required for endosomal protein trafficking in the yeast Saccharomyces cerevisiae
Q34888218The spindle assembly function of Caenorhabditis elegans katanin does not require microtubule-severing activity
Q36796834The torsin-family AAA+ protein OOC-5 contains a critical disulfide adjacent to Sensor-II that couples redox state to nucleotide binding
Q60938903The traffic ATPase PilF interacts with the inner membrane platform of the DNA translocator and type IV pili from
Q34360914The yeast vps class E mutants: the beginning of the molecular genetic analysis of multivesicular body biogenesis
Q35941012The β-Arrestin-Like Protein Rim8 Is Hyperphosphorylated and Complexes with Rim21 and Rim101 To Promote Adaptation to Neutral-Alkaline pH
Q47252504Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel.
Q48159191Tissue-specific expression and functional complementation of a yeast potassium-uptake mutant by a salt-induced ice plant gene mcSKD1.
Q34826835TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope
Q34336308TorsinA in the nuclear envelope
Q28087663Torsins: not your typical AAA+ ATPases
Q24681559Troyer syndrome protein spartin is mono-ubiquitinated and functions in EGF receptor trafficking
Q24291784Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding
Q36858880Tsg101 can replace Nedd4 function in ASV Gag release but not membrane targeting
Q24310372Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding
Q35761996ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins.
Q27939053Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.
Q42549736Ultrastructural analysis of nanogold-labeled endocytic compartments of yeast Saccharomyces cerevisiae using a cryosectioning procedure
Q26782995Ultrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesis
Q49789643VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis
Q64061665VPS4 triggers constriction and cleavage of ESCRT-III helical filaments
Q24652215Vacuolar protein sorting pathway contributes to the release of Marburg virus
Q39575922Vam7p, a SNAP-25-Like Molecule, and Vam3p, a Syntaxin Homolog, Function Together in Yeast Vacuolar Protein Trafficking
Q41862482Vesicle formation within endosomes: An ESCRT marks the spot
Q34338672Viral late domains
Q27000780Viral membrane scission
Q27931871Vps Factors Are Required for Efficient Transcription Elongation in Budding Yeast
Q24338164Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation
Q29620778Vps27 recruits ESCRT machinery to endosomes during MVB sorting
Q35685098Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation
Q43452567Vps4 regulates a subset of protein interactions at the multivesicular endosome
Q34317515Vps4 stimulatory element of the cofactor Vta1 contacts the ATPase Vps4 α7 and α9 to stimulate ATP hydrolysis
Q24534218Vps4-A (vacuolar protein sorting 4-A) is a binding partner for a novel Rho family GTPase, Rnd2
Q27934077Vta1p and Vps46p regulate the membrane association and ATPase activity of Vps4p at the yeast multivesicular body
Q38104257Where do they come from and where do they go: candidates for regulating extracellular vesicle formation in fungi
Q26992150Wrapping up the bad news: HIV assembly and release
Q42426686Yeast Mn2+ transporter, Smf1p, is regulated by ubiquitin-dependent vacuolar protein sorting
Q27935670Yeast PalA/AIP1/Alix Homolog Rim20p Associates with a PEST-Like Region and Is Required for Its Proteolytic Cleavage
Q33957947Yeast mutants affecting possible quality control of plasma membrane proteins
Q79091747p97, a protein coping with multiple identities

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