A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes

scientific article (publication date: 23 March 2016)

A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.13841
P3181OpenCitations bibliographic resource ID2828533
P932PMC publication ID4846373
P698PubMed publication ID27008177

P50authorAri HeleniusQ653682
Yohei YamauchiQ64682556
Jatta HuotariQ131711573
Matthias PeterQ58208774
Urs F GreberQ59829503
P2093author name stringChristopher A Barnes
Radoslav I Enchev
Anna Ulbricht
Ingrid Stoffel-Studer
Nathalie Meyer-Schaller
Michaela Gschweitl
P2860cites workK33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein TraffickingQ24295450
A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cellsQ24307672
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugationQ24314520
ATPase-deficient hVPS4 impairs formation of internal endosomal vesicles and stabilizes bilayered clathrin coats on endosomal vacuolesQ24336178
Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligaseQ24336527
The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome functionQ24533245
Biogenesis and function of multivesicular bodiesQ24601502
Systematic and quantitative assessment of the ubiquitin-modified proteomeQ24634631
Sequence and structural analysis of BTB domain proteinsQ24812693
Endosome maturationQ26992067
EGF receptor trafficking: consequences for signaling and cancerQ27021340
Building and remodelling Cullin-RING E3 ubiquitin ligasesQ27027816
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin LigasesQ27657740
The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activationQ27675805
Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosisQ28115833
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomesQ28205230
A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory rolesQ28247080
High-content analysis of sequential events during the early phase of influenza A virus infectionQ28534647
Recycling of the Epidermal Growth Factor Receptor Is Mediated by a Novel Form of the Clathrin Adaptor Protein Eps15Q28573403
Mechanisms of endocytosisQ29547609
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancerQ29616732
A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteinsQ29616733
Clathrin-independent endocytosis of ubiquitinated cargosQ33864329
Endocytosis of viruses and bacteriaQ33938568
Protein neddylation: beyond cullin-RING ligasesQ34042816
UIM domain-dependent recruitment of the endocytic adaptor protein Eps15 to ubiquitin-enriched endosomesQ34274663
eps15 and eps15R are essential components of the endocytic pathway.Q34450339
Regulation of ubiquitin-binding proteins by monoubiquitinationQ34486954
Stepwise priming by acidic pH and a high K+ concentration is required for efficient uncoating of influenza A virus cores after penetrationQ34594479
Rab proteins and the compartmentalization of the endosomal systemQ35548944
Cullin-3 regulates late endosome maturation.Q35735068
Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family.Q35740993
Deconjugation of Nedd8 from Cul1 Is Directly Regulated by Skp1-F-box and Substrate, and the COP9 Signalosome Inhibits Deneddylated SCF by a Noncatalytic MechanismQ36216079
eps15, A Novel Tyrosine Kinase Substrate, Exhibits Transforming ActivityQ36701817
Structural Basis for a Reciprocal Regulation between SCF and CSNQ36988986
Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugationQ37101488
Pooled RNAi screen identifies ubiquitin ligase Itch as crucial for influenza A virus release from the endosome during virus entryQ37255907
The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranesQ37282361
Role of endosomes and lysosomes in human disease.Q37718121
Governance of Endocytic Trafficking and Signaling by Reversible UbiquitylationQ38043227
Substrate recognition in selective autophagy and the ubiquitin-proteasome system.Q38094868
Entry of influenza A virus: host factors and antiviral targets.Q38162340
Ubiquitin-dependent sorting in endocytosisQ38175272
An endosomally localized isoform of Eps15 interacts with Hrs to mediate degradation of epidermal growth factor receptorQ38269635
USP9X Controls EGFR Fate by Deubiquitinating the Endocytic Adaptor Eps15.Q38805248
A mechanism for the suppression of homologous recombination in G1 cellsQ38813207
Influenza A virus uses the aggresome processing machinery for host cell entryQ38945386
Protein tyrosine phosphatase PTPN3 inhibits lung cancer cell proliferation and migration by promoting EGFR endocytic degradationQ38952578
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signallingQ40252247
The role of EGF receptor ubiquitination in regulating its intracellular trafficQ40507452
The Ubiquitin‐Vacuolar Protein Sorting System is Selectively Required During Entry of Influenza Virus into Host CellsQ40616491
The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cellsQ41867971
Eps15: a multifunctional adaptor protein regulating intracellular traffickingQ42198305
The tyrosine kinase substrate eps15 is constitutively associated with the plasma membrane adaptor AP-2Q42243078
Recycling of EGFR and ErbB2 is associated with impaired Hrs tyrosine phosphorylation and decreased deubiquitination by AMSHQ42832682
UBPY-mediated epidermal growth factor receptor (EGFR) de-ubiquitination promotes EGFR degradationQ42833376
Changes in the antigenicity of the hemagglutinin molecule of H3 influenza virus at acidic pH.Q45804797
Nuclear transport of influenza virus ribonucleoproteins: the viral matrix protein (M1) promotes export and inhibits importQ45854241
Molecular mechanisms of coupled monoubiquitinationQ57964128
P4510describes a project that usesImageJQ1659584
CellProfilerQ5058134
P407language of work or nameEnglishQ1860
P304page(s)e13841
P577publication date2016-03-23
P1433published ineLifeQ2000008
P1476titleA SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes
P478volume5

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cites work (P2860)
Q45323844Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans.
Q100311434Control of craniofacial and brain development by Cullin3-RING ubiquitin ligases: Lessons from human disease genetics
Q47284253Cullin 3-Based Ubiquitin Ligases as Master Regulators of Mammalian Cell Differentiation.
Q42697295Cullin-3 and its adaptor protein ANKFY1 determine the surface level of integrin β1 in endothelial cells
Q39074161Integration of cellular ubiquitin and membrane traffic systems: focus on deubiquitylases
Q92107647Life in the lumen: The multivesicular endosome
Q52654047Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking
Q39393272Role of Host Genes in Influenza Virus Replication
Q91713061SPOP and cancer: a systematic review
Q64290214The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells
Q28067104The ubiquitin system: a critical regulator of innate immunity and pathogen-host interactions
Q28077694Ubiquitin in Influenza Virus Entry and Innate Immunity
Q54224917Virus Entry: Looking Back and Moving Forward

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