Regulation of ubiquitin-binding proteins by monoubiquitination

scientific article

Regulation of ubiquitin-binding proteins by monoubiquitination is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1048714977
P356DOI10.1038/NCB1354
P8608Fatcat IDrelease_q54smuhfmbfwzhfuq7hybvqd6i
P698PubMed publication ID16429130
P5875ResearchGate publication ID7344008

P50authorIvan ĐikićQ832302
Harald StenmarkQ17109045
Rainer BreitlingQ38305239
Blagoy BlagoevQ42574438
Ritva TikkanenQ55190372
P2093author name stringMatthias Mann
Camilla Raiborg
Daniela Hoeller
Nicola Crosetto
Sebastian Wagner
Katarzyna Kowanetz
P2860cites workUbiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitmentQ24306128
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomesQ24313594
Hrs recruits clathrin to early endosomesQ24535764
Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomicsQ28277407
Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2Q28587191
Ubiquitin-binding domainsQ29614358
A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteinsQ29616733
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomesQ29619337
Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesisQ29619757
Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradationQ29622825
Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinasesQ30164059
TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitinQ30164133
Ligand-independent degradation of epidermal growth factor receptor involves receptor ubiquitylation and Hgs, an adaptor whose ubiquitin-interacting motif targets ubiquitylation by Nedd4.Q33292150
The association of epsin with ubiquitinated cargo along the endocytic pathway is negatively regulated by its interaction with clathrinQ33864158
Clathrin-independent endocytosis of ubiquitinated cargosQ33864329
Rapid Ca2+-dependent decrease of protein ubiquitination at synapsesQ34388074
When ubiquitin meets ubiquitin receptors: a signalling connectionQ35141760
Ubiquitylation and cell signalingQ36251951
Improved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentationQ37533698
Analysis of the role of ubiquitin-interacting motifs in ubiquitin binding and ubiquitylationQ40553487
Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not PolyubiquitylationQ44420471
The UIM domain of Hrs couples receptor sorting to vesicle formationQ44571725
c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15.Q45071274
Membrane-permeable cygnets: rapid cellular internalization of fluorescent cGMP-indicators.Q52656017
Membrane Transport: A Coat for UbiquitinQ57980017
P433issue2
P304page(s)163-169
P577publication date2006-01-22
P1433published inNature Cell BiologyQ1574111
P1476titleRegulation of ubiquitin-binding proteins by monoubiquitination
P478volume8

Reverse relations

cites work (P2860)
Q5353238714-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase.
Q37669871A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.
Q27646954A Phosphatase Activity of Sts-1 Contributes to the Suppression of TCR Signaling
Q28834146A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes
Q27728163A bacterial genetic selection system for ubiquitylation cascade discovery
Q35998598A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting
Q24336773A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets
Q40252247A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling
Q46181219A ubiquitin-interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome
Q39962046ABINs inhibit EGF receptor-mediated NF-kappaB activation and growth of EGF receptor-overexpressing tumour cells
Q35562523Adaptor protein complex-2 (AP-2) and epsin-1 mediate protease-activated receptor-1 internalization via phosphorylation- and ubiquitination-dependent sorting signals.
Q36773146Analysis of oxygen/glucose-deprivation-induced changes in SUMO3 conjugation using SILAC-based quantitative proteomics
Q33992591Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4
Q38084832Atypical protein phosphatases: emerging players in cellular signaling
Q24655287Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series
Q27647842Autoregulation of the Rsc4 Tandem Bromodomain by Gcn5 Acetylation
Q24601502Biogenesis and function of multivesicular bodies
Q40157263C-terminal modifications regulate MDM2 dissociation and nuclear export of p53.
Q60305294CD5, an Undercover Regulator of TCR Signaling
Q24294662CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery
Q24298867CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4
Q36332068Cellular strategies for making monoubiquitin signals
Q42024376Contributions of ubiquitin- and PCNA-binding domains to the activity of Polymerase eta in Saccharomyces cerevisiae
Q37419861Degradation of activated protein kinases by ubiquitination
Q33645197Determination of the Substrate Specificity of Protein-tyrosine Phosphatase TULA-2 and Identification of Syk as a TULA-2 Substrate
Q90088711Deubiquitinases: Pro-oncogenic Activity and Therapeutic Targeting in Blood Malignancies
Q27679962Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications
Q43158611Distinct recruitment of Eps15 via Its coiled-coil domain is required for efficient down-regulation of the met receptor tyrosine kinase
Q36748155Downregulation of vertebrate Tel (ETV6) and Drosophila Yan is facilitated by an evolutionarily conserved mechanism of F-box-mediated ubiquitination
Q36228483Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation
Q57269969EGFR trafficking: parkin' in a jam
Q37707470ESCRT & Co.
Q27931999ESCRT ubiquitin-binding domains function cooperatively during MVB cargo sorting
Q36594142Efficient and specific rescue of human immunodeficiency virus type 1 budding defects by a Nedd4-like ubiquitin ligase
Q28084524Emerging roles of PtdIns(4,5)P2--beyond the plasma membrane
Q27008073Endocytic trafficking of chemokine receptors
Q37980726Endocytosis and signaling: cell logistics shape the eukaryotic cell plan
Q37086712Endosomal type Iγ PIP 5-kinase controls EGF receptor lysosomal sorting
Q42081863Epidermal growth factor receptor fate is controlled by Hrs tyrosine phosphorylation sites that regulate Hrs degradation
Q28583911Eps15 interacts with ubiquitinated Cx43 and mediates its internalization
Q36796883Eps15 mediates vesicle trafficking from the trans-Golgi network via an interaction with the clathrin adaptor AP-1.
Q42198305Eps15: a multifunctional adaptor protein regulating intracellular trafficking
Q36082927Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification
Q35201519Guidelines for visualizing and annotating rule-based models
Q47344775Gαs protein binds ubiquitin to regulate epidermal growth factor receptor endosomal sorting
Q30159582Hse1, a component of the yeast Hrs-STAM ubiquitin-sorting complex, associates with ubiquitin peptidases and a ligase to control sorting efficiency into multivesicular bodies
Q42957098Hsp70 negatively controls rotavirus protein bioavailability in caco-2 cells infected by the rotavirus RF strain
Q27654065Hybrid Structural Model of the Complete Human ESCRT-0 Complex
Q24318462ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity
Q28253409In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy
Q33792527Inducible STAT3 NH2 terminal mono-ubiquitination promotes BRD4 complex formation to regulate apoptosis
Q39351203Induction of pancreatic cancer cell apoptosis and enhancement of gemcitabine sensitivity by RAP80 siRNA.
Q24315604Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes
Q36387588It Takes 15 to Tango: Making Sense of the Many Ubiquitin Ligases of p53.
Q30360833LAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation.
Q35017553Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor
Q39668561Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8.
Q39584472MDA-9/syntenin interacts with ubiquitin via a novel ubiquitin-binding motif.
Q57964128Molecular mechanisms of coupled monoubiquitination
Q90641134Molecular recognition of ubiquitin and Lys63-linked diubiquitin by STAM2 UIM-SH3 dual domain: the effect of its linker length and flexibility
Q41257869Monoubiquitination of RPN10 regulates substrate recruitment to the proteasome.
Q24312760Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling
Q40037116Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells
Q37566975Multitasking with ubiquitin through multivalent interactions
Q52644438New Insights into the Role of E2s in the Pathogenesis of Diseases: Lessons Learned from UBE2O.
Q28594861Novel variant of neuronal intranuclear rodlet immunoreactive for 40 kDa huntingtin associated protein and ubiquitin in the mouse brain
Q37181954Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination
Q35901860PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal
Q27935429Pkh1/2-dependent phosphorylation of Vps27 regulates ESCRT-I recruitment to endosomes
Q36017039Plasticity of polyubiquitin recognition as lysosomal targeting signals by the endosomal sorting machinery
Q37760036Post-translational modifications in signal integration
Q34041809Post-translational modifications of exosomal proteins
Q36554464Protein monoubiquitylation: targets and diverse functions
Q92965953Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins
Q41780704Purification and crystallization of mono-ubiquitylated ubiquitin receptor Rpn10.
Q24670038RAP80 interacts with the SUMO-conjugating enzyme UBC9 and is a novel target for sumoylation
Q36215880RalA and RalB proteins are ubiquitinated GTPases, and ubiquitinated RalA increases lipid raft exposure at the plasma membrane
Q29622877Reading protein modifications with interaction domains
Q37559669Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins.
Q28573403Recycling of the epidermal growth factor receptor is mediated by a novel form of the clathrin adaptor protein Eps15
Q24621192Regulation of Epidermal Growth Factor Receptor Ubiquitination and Trafficking by the USP8·STAM Complex
Q40172752Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo.
Q27940151Regulation of clathrin-mediated endocytosis by dynamic ubiquitination and deubiquitination
Q38256371Regulation of fc receptor endocytic trafficking by ubiquitination.
Q28087183Regulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteins
Q35531278Replication of the rotavirus genome requires an active ubiquitin-proteasome system
Q24301513Rin1 interacts with signal-transducing adaptor molecule (STAM) and mediates epidermal growth factor receptor trafficking and degradation
Q37479242SHIP2 (SH2 domain-containing inositol phosphatase 2) SH2 domain negatively controls SHIP2 monoubiquitination in response to epidermal growth factor
Q81543245SPIN1, a K homology domain protein negatively regulated and ubiquitinated by the E3 ubiquitin ligase SPL11, is involved in flowering time control in rice
Q36839119SUMO junction-what's your function? New insights through SUMO-interacting motifs
Q42572392SUMO takes control of a ubiquitin-specific protease
Q39185970Selective Targeting of a Novel Epsin-VEGFR2 Interaction Promotes VEGF-Mediated Angiogenesis.
Q36692317Sequestosome 1/p62--more than just a scaffold
Q34197088Signaling-mediated control of ubiquitin ligases in endocytosis.
Q42205588Site-specific monoubiquitination downregulates Rab5 by disrupting effector binding and guanine nucleotide conversion
Q36176561Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis
Q43252764Small ubiquitin-related modifier (SUMO) binding determines substrate recognition and paralog-selective SUMO modification
Q24337603Spartan/C1orf124, a reader of PCNA ubiquitylation and a regulator of UV-induced DNA damage response
Q36418897Spatiotemporal regulation of the ubiquitinated cargo-binding activity of Rabex-5 in the endocytic pathway
Q35947104Split-ubiquitin two-hybrid assay to analyze protein-protein interactions at the endosome: application to Saccharomyces cerevisiae Bro1 interacting with ESCRT complexes, the Doa4 ubiquitin hydrolase, and the Rsp5 ubiquitin ligase
Q41429616Structure of ubiquitylated-Rpn10 provides insight into its autoregulation mechanism.
Q34963266Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways
Q28248770Suppression of the ligand-mediated down-regulation of epidermal growth factor receptor by Ymer, a novel tyrosine-phosphorylated and ubiquitinated protein
Q30157759Suppressor of T-cell receptor signalling 1 and 2 differentially regulate endocytosis and signalling of receptor tyrosine kinases
Q28578369Syk-dependent regulation of Hrs phosphorylation and ubiquitination upon FcεRI engagement: impact on Hrs membrane/cytosol localization
Q40514576Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria.
Q34713979TULA proteins bind to ABCE-1, a host factor of HIV-1 assembly, and inhibit HIV-1 biogenesis in a UBA-dependent fashion.
Q38017998TULA-family proteins: a new class of cellular regulators
Q42162615Terminating protein ubiquitination: Hasta la vista, ubiquitin.
Q35861829The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane
Q96303690The Beginning of the End: Initial Steps in the Degradation of Plasma Membrane Proteins
Q24569667The Deubiquitinating Enzyme USP8 Promotes Trafficking and Degradation of the Chemokine Receptor 4 at the Sorting Endosome
Q48228631The EGFR odyssey - from activation to destruction in space and time.
Q24569709The ESCRT complexes
Q29617399The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
Q26849199The ESCRT machinery: from the plasma membrane to endosomes and back again
Q51577116The Extended Family of Protein Tyrosine Phosphatases.
Q38285213The Fanconi anemia ID2 complex: dueling saxes at the crossroads
Q35001723The IκB kinase complex in NF-κB regulation and beyond
Q38835640The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness.
Q24310107The Polycomb-associated protein Rybp is a ubiquitin binding protein
Q39947573The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11.
Q36399027The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function
Q38634867The extended human PTPome: a growing tyrosine phosphatase family
Q33957071The function of yeast epsin and Ede1 ubiquitin-binding domains during receptor internalization
Q91199451The many functions of ESCRTs
Q39193083The protease activity of the paracaspase MALT1 is controlled by monoubiquitination.
Q35213144The role of ITCH protein in human T-cell leukemia virus type 1 release
Q36889025The role of ubiquitin in retroviral egress
Q37395713The scaffold protein PDZK1 undergoes a head-to-tail intramolecular association that negatively regulates its interaction with EBP50.
Q33747115The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4
Q28067104The ubiquitin system: a critical regulator of innate immunity and pathogen-host interactions
Q24652479The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response
Q33412039The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition
Q28386906The ubiquitin-proteasome system in spongiform degenerative disorders
Q47115157The ubiquitin-proteasome system is required for African swine fever replication
Q36268060The ubiquitin-proteasome system of Saccharomyces cerevisiae
Q33343831The ubiquitination code: a signalling problem
Q28569172Tollip is a mediator of protein sumoylation
Q24681559Troyer syndrome protein spartin is mono-ubiquitinated and functions in EGF receptor trafficking
Q48290135UBASH3A Mediates Risk for Type 1 Diabetes Through Inhibition of T-Cell Receptor-Induced NF-κB Signaling
Q63384325USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7
Q39376341Ubc13 and COOH terminus of Hsp70-interacting protein (CHIP) are required for growth hormone receptor endocytosis
Q24653688Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
Q57979502UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
Q30846736Ubiquitin Receptor Protein UBASH3B Drives Aurora B Recruitment to Mitotic Microtubules
Q30010083Ubiquitin and its binding domains.
Q36601000Ubiquitin and ubiquitin-like proteins in cancer pathogenesis
Q37325110Ubiquitin in trafficking: the network at work
Q37978888Ubiquitin links to cytoskeletal dynamics, cell adhesion and migration
Q29616461Ubiquitin-binding domains
Q29614829Ubiquitin-binding domains - from structures to functions
Q38175272Ubiquitin-dependent sorting in endocytosis
Q36906047Ubiquitin-dependent sorting of integral membrane proteins for degradation in lysosomes
Q37894280Ubiquitin-family modifications in the replication of DNA damage
Q35781803Ubiquitin-interaction motifs of RAP80 are critical in its regulation of estrogen receptor alpha.
Q33750025Ubiquitin-regulated nuclear-cytoplasmic trafficking of the Nipah virus matrix protein is important for viral budding
Q38287957Ubiquitination as an efficient molecular strategy employed in salmonella infection
Q36118471Ubiquitination differentially regulates clathrin-dependent internalization of protease-activated receptor-1
Q88037974Ubiquitination-mediated interaction among domains is responsible for inhibition of RNA endonuclease activity of mRNA cycling sequence binding protein from L. donovani (LdCSBP)
Q37661680Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation in Arabidopsis
Q39030641Ubiquitylation-dependent oligomerization regulates activity of Nedd4 ligases.
Q34774715Versatile roles of k63-linked ubiquitin chains in trafficking
Q39283831Volume expansion stimulates monoubiquitination and endocytosis of surface-expressed skate anion-exchanger isoform
Q57912462Working out coupled monoubiquitination
Q34821486gamma2-Adaptin, a ubiquitin-interacting adaptor, is a substrate to coupled ubiquitination by the ubiquitin ligase Nedd4 and functions in the endosomal pathway

Search more.