Atypical protein phosphatases: emerging players in cellular signaling

scientific article published on 26 February 2013

Atypical protein phosphatases: emerging players in cellular signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS14034596
P932PMC publication ID3634448
P698PubMed publication ID23443160
P5875ResearchGate publication ID235740207

P2093author name stringKohsuke Takeda
Susumu Tanimura
Daichi Sadatomi
Kei-Ichi Ozaki
P2860cites workCharacterization of the threonine-phosphatase of mouse eyes absent 3Q84705559
PINK1 is selectively stabilized on impaired mitochondria to activate ParkinQ21145802
Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's diseaseQ24294218
Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signalingQ24298930
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathwaysQ24302411
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damageQ24306743
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathwaysQ24309037
Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1Q24312673
PINK1 cleavage at position A103 by the mitochondrial protease PARL.Q24313472
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisionsQ24313501
Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absentQ24313879
A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene familyQ24318377
The protein kinase complement of the human genomeQ24324497
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alphaQ24338113
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammationQ24338129
Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing proteinQ24540267
T cell activationQ24658051
A 4-bp insertion in the eya-homologous region (eyaHR) of EYA4 causes hearing impairment in a Hungarian family linked to DFNA10Q24676401
A Phosphatase Activity of Sts-1 Contributes to the Suppression of TCR SignalingQ27646954
Structure, function, and evolution of phosphoglycerate mutases: comparison with fructose-2,6-bisphosphatase, acid phosphatase, and alkaline phosphataseQ28144542
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesisQ28185761
BOR and BO syndromes are allelic defects of EYA1Q28253634
Serine/threonine phosphatases: mechanism through structureQ28263239
Protein tyrosine phosphatases in the human genomeQ28265924
PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondriaQ28384526
Inhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosisQ28395156
The EYA tyrosine phosphatase activity is pro-angiogenic and is inhibited by benzbromaroneQ28482486
Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulationQ35868311
IAPs, RINGs and ubiquitylationQ36085601
Profiling of UV-induced ATM/ATR signaling pathways.Q36288898
Substrates of IAP ubiquitin ligases identified with a designed orthogonal E3 ligase, the NEDDylatorQ36569330
The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcriptionQ36752910
Apoptosis signal-regulating kinase 1 in stress and immune responseQ36947070
The histidine phosphatase superfamily: structure and functionQ37037661
TULA-family proteins: an odd coupleQ37544376
Ubiquitylation in apoptosis: a post-translational modification at the edge of life and deathQ37893455
Regulation of the innate immune response by threonine-phosphatase of Eyes absentQ39831920
TULA proteins regulate activity of the protein tyrosine kinase Syk.Q40026226
PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complexQ40219081
Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5Q42051309
The transcription factor Eyes absent is a protein tyrosine phosphataseQ44662320
Mutations in the transcriptional activator EYA4 cause late-onset deafness at the DFNA10 locusQ28575439
Eya4-deficient mice are a model for heritable otitis mediaQ28585781
Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2Q28587191
Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordiaQ28587212
Eyes absent represents a class of protein tyrosine phosphatasesQ28593158
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosisQ28594624
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARLQ29615624
Molecular mechanisms of necroptosis: an ordered cellular explosionQ29616004
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagyQ29616005
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancerQ29616499
Suppressor of T-cell receptor signalling 1 and 2 differentially regulate endocytosis and signalling of receptor tyrosine kinasesQ30157759
The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosisQ30158019
Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinasesQ30164059
TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitinQ30164133
Isolation and characterization of the UBASH3A gene on 21q22.3 encoding a potential nuclear protein with a novel combination of domainsQ30168322
In vitro selection and characterization of Bcl-X(L)-binding proteins from a mix of tissue-specific mRNA display librariesQ31889951
Pleiotropic effects in Eya3 knockout miceQ33395094
Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosisQ33604218
Determination of the Substrate Specificity of Protein-tyrosine Phosphatase TULA-2 and Identification of Syk as a TULA-2 SubstrateQ33645197
Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial networkQ33746288
The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in DrosophilaQ33769553
The Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration, and invasion of tumor cellsQ33940667
Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growthQ34025197
Prevention of apoptosis by mitochondrial phosphatase PGAM5 in the mushroom body is crucial for heat shock resistance in Drosophila melanogasterQ34162494
The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye.Q34360299
Drosophila EYA regulates the immune response against DNA through an evolutionarily conserved threonine phosphatase motifQ34390966
Transcriptional coactivator Drosophila eyes absent homologue 2 is up-regulated in epithelial ovarian cancer and promotes tumor growth.Q34393314
A gene for autosomal dominant late-onset progressive non-syndromic hearing loss, DFNA10, maps to chromosome 6.Q34394216
Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing lossQ34398395
Regulation of ubiquitin-binding proteins by monoubiquitinationQ34486954
The structure, regulation, and function of ZAP-70.Q34605479
NF-κB/Rel proteins and the humoral immune responses of Drosophila melanogasterQ34877184
Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathwaysQ34963266
Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell propertiesQ35243673
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)4596-4612
P577publication date2013-02-26
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleAtypical protein phosphatases: emerging players in cellular signaling
P478volume14

Reverse relations

cites work (P2860)
Q34139093A conserved motif mediates both multimer formation and allosteric activation of phosphoglycerate mutase 5.
Q35924241EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk
Q43094561Editorial of the special issue: signaling molecules and signal transduction in cells
Q39888524Epigenetic mediated silencing of EYA4 contributes to tumorigenesis in oral dysplastic cells
Q38752395Global RT-PCR and RT-qPCR Analysis of the mRNA Expression of the Human PTPome.
Q45731163Identification of PGAM5 as a Mammalian Protein Histidine Phosphatase that Plays a Central Role to Negatively Regulate CD4(+) T Cells
Q91817291Insights into the pathophysiology of DFNA10 hearing loss associated with novel EYA4 variants
Q64245074Protein Phosphatases-A Touchy Enemy in the Battle Against Glioblastomas: A Review
Q28075591Protein phosphorylation and its role in archaeal signal transduction
Q38941676Role of protein phosphatases in genitourinary cancers
Q40961063Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly
Q91596634Syntaxin 17 regulates the localization and function of PGAM5 in mitochondrial division and mitophagy
Q38730574The Atypical Dual Specificity Phosphatase hYVH1 Associates with Multiple Ribonucleoprotein Particles

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