scholarly article | Q13442814 |
P2093 | author name string | Kohsuke Takeda | |
Susumu Tanimura | |||
Daichi Sadatomi | |||
Kei-Ichi Ozaki | |||
P2860 | cites work | Characterization of the threonine-phosphatase of mouse eyes absent 3 | Q84705559 |
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin | Q21145802 | ||
Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease | Q24294218 | ||
Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling | Q24298930 | ||
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways | Q24302411 | ||
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage | Q24306743 | ||
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways | Q24309037 | ||
Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1 | Q24312673 | ||
PINK1 cleavage at position A103 by the mitochondrial protease PARL. | Q24313472 | ||
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions | Q24313501 | ||
Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent | Q24313879 | ||
A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family | Q24318377 | ||
The protein kinase complement of the human genome | Q24324497 | ||
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha | Q24338113 | ||
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation | Q24338129 | ||
Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein | Q24540267 | ||
T cell activation | Q24658051 | ||
A 4-bp insertion in the eya-homologous region (eyaHR) of EYA4 causes hearing impairment in a Hungarian family linked to DFNA10 | Q24676401 | ||
A Phosphatase Activity of Sts-1 Contributes to the Suppression of TCR Signaling | Q27646954 | ||
Structure, function, and evolution of phosphoglycerate mutases: comparison with fructose-2,6-bisphosphatase, acid phosphatase, and alkaline phosphatase | Q28144542 | ||
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis | Q28185761 | ||
BOR and BO syndromes are allelic defects of EYA1 | Q28253634 | ||
Serine/threonine phosphatases: mechanism through structure | Q28263239 | ||
Protein tyrosine phosphatases in the human genome | Q28265924 | ||
PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria | Q28384526 | ||
Inhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosis | Q28395156 | ||
The EYA tyrosine phosphatase activity is pro-angiogenic and is inhibited by benzbromarone | Q28482486 | ||
Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation | Q35868311 | ||
IAPs, RINGs and ubiquitylation | Q36085601 | ||
Profiling of UV-induced ATM/ATR signaling pathways. | Q36288898 | ||
Substrates of IAP ubiquitin ligases identified with a designed orthogonal E3 ligase, the NEDDylator | Q36569330 | ||
The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription | Q36752910 | ||
Apoptosis signal-regulating kinase 1 in stress and immune response | Q36947070 | ||
The histidine phosphatase superfamily: structure and function | Q37037661 | ||
TULA-family proteins: an odd couple | Q37544376 | ||
Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death | Q37893455 | ||
Regulation of the innate immune response by threonine-phosphatase of Eyes absent | Q39831920 | ||
TULA proteins regulate activity of the protein tyrosine kinase Syk. | Q40026226 | ||
PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex | Q40219081 | ||
Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5 | Q42051309 | ||
The transcription factor Eyes absent is a protein tyrosine phosphatase | Q44662320 | ||
Mutations in the transcriptional activator EYA4 cause late-onset deafness at the DFNA10 locus | Q28575439 | ||
Eya4-deficient mice are a model for heritable otitis media | Q28585781 | ||
Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2 | Q28587191 | ||
Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia | Q28587212 | ||
Eyes absent represents a class of protein tyrosine phosphatases | Q28593158 | ||
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis | Q28594624 | ||
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL | Q29615624 | ||
Molecular mechanisms of necroptosis: an ordered cellular explosion | Q29616004 | ||
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy | Q29616005 | ||
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer | Q29616499 | ||
Suppressor of T-cell receptor signalling 1 and 2 differentially regulate endocytosis and signalling of receptor tyrosine kinases | Q30157759 | ||
The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis | Q30158019 | ||
Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases | Q30164059 | ||
TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin | Q30164133 | ||
Isolation and characterization of the UBASH3A gene on 21q22.3 encoding a potential nuclear protein with a novel combination of domains | Q30168322 | ||
In vitro selection and characterization of Bcl-X(L)-binding proteins from a mix of tissue-specific mRNA display libraries | Q31889951 | ||
Pleiotropic effects in Eya3 knockout mice | Q33395094 | ||
Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis | Q33604218 | ||
Determination of the Substrate Specificity of Protein-tyrosine Phosphatase TULA-2 and Identification of Syk as a TULA-2 Substrate | Q33645197 | ||
Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network | Q33746288 | ||
The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila | Q33769553 | ||
The Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration, and invasion of tumor cells | Q33940667 | ||
Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growth | Q34025197 | ||
Prevention of apoptosis by mitochondrial phosphatase PGAM5 in the mushroom body is crucial for heat shock resistance in Drosophila melanogaster | Q34162494 | ||
The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye. | Q34360299 | ||
Drosophila EYA regulates the immune response against DNA through an evolutionarily conserved threonine phosphatase motif | Q34390966 | ||
Transcriptional coactivator Drosophila eyes absent homologue 2 is up-regulated in epithelial ovarian cancer and promotes tumor growth. | Q34393314 | ||
A gene for autosomal dominant late-onset progressive non-syndromic hearing loss, DFNA10, maps to chromosome 6. | Q34394216 | ||
Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss | Q34398395 | ||
Regulation of ubiquitin-binding proteins by monoubiquitination | Q34486954 | ||
The structure, regulation, and function of ZAP-70. | Q34605479 | ||
NF-κB/Rel proteins and the humoral immune responses of Drosophila melanogaster | Q34877184 | ||
Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways | Q34963266 | ||
Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties | Q35243673 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 4596-4612 | |
P577 | publication date | 2013-02-26 | |
P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
P1476 | title | Atypical protein phosphatases: emerging players in cellular signaling | |
P478 | volume | 14 |
Q34139093 | A conserved motif mediates both multimer formation and allosteric activation of phosphoglycerate mutase 5. |
Q35924241 | EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk |
Q43094561 | Editorial of the special issue: signaling molecules and signal transduction in cells |
Q39888524 | Epigenetic mediated silencing of EYA4 contributes to tumorigenesis in oral dysplastic cells |
Q38752395 | Global RT-PCR and RT-qPCR Analysis of the mRNA Expression of the Human PTPome. |
Q45731163 | Identification of PGAM5 as a Mammalian Protein Histidine Phosphatase that Plays a Central Role to Negatively Regulate CD4(+) T Cells |
Q91817291 | Insights into the pathophysiology of DFNA10 hearing loss associated with novel EYA4 variants |
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Q38941676 | Role of protein phosphatases in genitourinary cancers |
Q40961063 | Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly |
Q91596634 | Syntaxin 17 regulates the localization and function of PGAM5 in mitochondrial division and mitophagy |
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