Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein

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Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein is …
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scholarly articleQ13442814

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P356DOI10.1128/MCB.22.21.7491-7500.2002
P932PMC publication ID135669
P698PubMed publication ID12370296

P2093author name stringHideaki Nakajima
James N Ihle
Yutaka Takahashi
Heesuk Zang
Nick Carpino
Ryuji Kobayashi
Jian Feng
Shiann-Tarrng Jou
P2860cites workJak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesisQ24316448
The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesisQ24550897
Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bbetaQ24554240
Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loopQ24646491
The crystal structure of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase reveals distinct domain homologiesQ27733404
The Pfam protein families databaseQ27860470
Signaling through scaffold, anchoring, and adaptor proteinsQ28131792
SH2-B and SIRP: JAK2 binding proteins that modulate the actions of growth hormoneQ28141554
Structure, function, and evolution of phosphoglycerate mutases: comparison with fructose-2,6-bisphosphatase, acid phosphatase, and alkaline phosphataseQ28144542
STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc inductionQ28236871
JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietinQ28260976
Jak2 is essential for signaling through a variety of cytokine receptorsQ28270987
Structural basis for the binding of proline-rich peptides to SH3 domainsQ29620408
Signaling by type I and II cytokine receptors: ten years afterQ33951373
B cell development pathwaysQ34178187
Evolution of a bifunctional enzyme: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphataseQ34324537
Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response.Q36558498
A novel negative selection for homologous recombinants using diphtheria toxin A fragment gene.Q36756801
Cellular adherence elicits ligand-independent activation of the Met cell-surface receptorQ37404891
Origins and properties of hematopoietic growth factor-dependent cell lines.Q38633693
Targeted gene replacement.Q40728488
Janus kinases in cytokine signallingQ40998216
The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferationQ41117299
Erythropoietin-induced recruitment of Shc via a receptor phosphotyrosine-independent, Jak2-associated pathwayQ41346191
Skeletal muscles of mice deficient in muscle creatine kinase lack burst activityQ57190014
Active site sequence of hepatic fructose-2,6-bisphosphatase. Homology in primary structure with phosphoglycerate mutaseQ70192341
Signaling by the cytokine receptor superfamilyQ77934807
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
SH3 domainQ24771787
P304page(s)7491-7500
P577publication date2002-11-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleIdentification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein
P478volume22

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cites work (P2860)
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Q28116068Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity
Q24317707Charting the molecular network of the drug target Bcr-Abl
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Q42673182Members of the novel UBASH3/STS/TULA family of cellular regulators suppress T-cell-driven inflammatory responses in vivo
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Q35868311Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation
Q40219081PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex
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Q36739652Recent advances in growth hormone signaling
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Q28586059TULA-2, a novel histidine phosphatase, regulates bone remodeling by modulating osteoclast function
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Q97643346UBASH3A deficiency accelerates type 1 diabetes development and enhances salivary gland inflammation in NOD mice

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