Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways

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Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M110.177634
P932PMC publication ID3091203
P698PubMed publication ID21393235

P2093author name stringNick Carpino
Nicolas Nassar
Boris San Luis
Ben Sondgeroth
P2860cites workMitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signalingQ24293054
Large-scale structural analysis of the classical human protein tyrosine phosphatomeQ24321557
Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing proteinQ24540267
The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates beta-cateninQ24679774
A Phosphatase Activity of Sts-1 Contributes to the Suppression of TCR SignalingQ27646954
Structural and Functional Characterization of the 2H-Phosphatase Domain of Sts-2 Reveals an Acid-Dependent Phosphatase Activity †Q27653664
Structure, function, and evolution of phosphoglycerate mutases: comparison with fructose-2,6-bisphosphatase, acid phosphatase, and alkaline phosphataseQ28144542
Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase DQ28245266
The structure and mechanism of protein phosphatases: insights into catalysis and regulationQ28275119
Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2Q28587191
Suppressor of T-cell receptor signalling 1 and 2 differentially regulate endocytosis and signalling of receptor tyrosine kinasesQ30157759
Crystallization and initial crystal characterization of the C-terminal phosphoglycerate mutase homology domain of Sts-1.Q30159888
Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinasesQ30164059
TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitinQ30164133
Requirement for phospholipase C-gamma1 enzymatic activity in growth factor-induced mitogenesisQ30176334
Structures of the phosphorylated and VO(3)-bound 2H-phosphatase domain of Sts-2.Q33644549
Determination of the Substrate Specificity of Protein-tyrosine Phosphatase TULA-2 and Identification of Syk as a TULA-2 SubstrateQ33645197
Regulation of ubiquitin-binding proteins by monoubiquitinationQ34486954
The structure, regulation, and function of ZAP-70.Q34605479
T-cell ubiquitin ligand affects cell death through a functional interaction with apoptosis-inducing factor, a key factor of caspase-independent apoptosisQ34665121
T cell receptor signaling: beyond complex complexesQ35745872
Multiple signal transduction pathways activated through the T cell receptor for antigenQ36716683
The histidine phosphatase superfamily: structure and functionQ37037661
Multidomain STS/TULA proteins are novel cellular regulatorsQ37111363
Tailoring T-cell receptor signals by proximal negative feedback mechanismsQ37252710
The Sts proteins target tyrosine phosphorylated, ubiquitinated proteins within TCR signaling pathwaysQ37376318
TULA-family proteins: an odd coupleQ37544376
Overview of the immune responseQ37696715
ZAP-70: an essential kinase in T-cell signalingQ37746517
TULA proteins regulate activity of the protein tyrosine kinase Syk.Q40026226
Kinetic analysis of the catalytic domain of human cdc25B.Q40922684
The biology of the immune systemQ41660135
3,6-Fluorescein Diphosphate: A Sensitive Fluorogenic and Chromogenic Substrate for Protein Tyrosine Phosphatases*Q73851646
Fluorescein monophosphates as fluorogenic substrates for protein tyrosine phosphatasesQ77343359
P433issue18
P407language of work or nameEnglishQ1860
P304page(s)15943-15954
P577publication date2011-03-10
P1433published inJournal of Biological ChemistryQ867727
P1476titleSts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways
P478volume286