TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin

scientific article

TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1034421560
P356DOI10.1038/SJ.ONC.1207627
P698PubMed publication ID15107835
P5875ResearchGate publication ID8597030

P2093author name stringHamid Band
Roland S Annan
Steven A Carr
Alexander Y Tsygankov
Xiaolong Zhang
Rachana Agrawal
Gayathri Swaminathan
Evgeniya V Smirnova
Elena A Feshchenko
Anjali M Teckchandani
P2860cites workStimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3GQ24309656
Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinaseQ27617539
Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligasesQ27626747
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cellsQ27860599
Probability-based protein identification by searching sequence databases using mass spectrometry dataQ27860736
UBA domains of DNA damage-inducible proteins interact with ubiquitinQ27935487
cbl-b inhibits epidermal growth factor receptor signalingQ28139234
The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligaseQ28145635
Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7Q28146026
c-Cbl associates directly with the C-terminal tail of the receptor for the macrophage colony-stimulating factor, c-Fms, and down-modulates this receptor but not the viral oncogene v-FmsQ28201688
Negative regulation of Lck by Cbl ubiquitin ligaseQ28208259
Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming proteinQ28210330
c-Cbl facilitates fibronectin matrix production by v-Abl-transformed NIH3T3 cells via activation of small GTPasesQ28213787
Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cellsQ28609046
Transcription factors: structural families and principles of DNA recognitionQ29615317
Analysis of gene function in somatic mammalian cells using small interfering RNAsQ29616541
Activation of the Src-family tyrosine kinase Hck by SH3 domain displacementQ30014848
Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.Q31109069
Altered thymic positive selection and intracellular signals in Cbl-deficient miceQ33596728
Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complexQ33948376
Cbl: many adaptations to regulate protein tyrosine kinasesQ34205572
WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradationQ34220865
Beyond the RING: CBL proteins as multivalent adaptersQ34405560
Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptorsQ34806104
The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alphaQ36164471
Alternative intracellular routing of ErbB receptors may determine signaling potencyQ38337018
Tip, an Lck-interacting protein of Herpesvirus saimiri, causes Fas- and Lck-dependent apoptosis of T lymphocytesQ40579458
Cbl-mediated Ubiquitinylation Is Required for Lysosomal Sorting of Epidermal Growth Factor Receptor but Is Dispensable for EndocytosisQ40646939
C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminusQ40750172
Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70.Q40806098
Herpesvirus saimiri oncoproteins Tip and StpC synergistically stimulate NF-kappaB activity and interleukin-2 gene expressionQ40833744
c-Cbl is a suppressor of the neu oncogeneQ40862177
The linker phosphorylation site Tyr292 mediates the negative regulatory effect of Cbl on ZAP-70 in T cellsQ40884199
Leucine zipper-mediated homodimerization of the adaptor protein c-Cbl. A role in c-Cbl's tyrosine phosphorylation and its association with epidermal growth factor receptorQ40923031
The proto-oncogene c-Cbl is a negative regulator of DNA synthesis initiated by both receptor and cytoplasmic tyrosine kinasesQ40949624
Formation of c-Cbl.phosphatidylinositol 3-kinase complexes on lymphocyte membranes by a p56lck-independent mechanismQ41168715
Diminished tyrosine protein kinase activity in T cells unresponsive to TCR stimulation.Q41483385
UBA domains mediate protein-protein interactions between two DNA damage-inducible proteinsQ42663494
Ligand-induced lysosomal epidermal growth factor receptor (EGFR) degradation is preceded by proteasome-dependent EGFR de-ubiquitinationQ42800213
Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domainQ42815138
Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodiesQ42917525
Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteinsQ43670938
Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not PolyubiquitylationQ44420471
Identification of phosphorylation sites in proteins separated by polyacrylamide gel electrophoresisQ48022079
The RING Finger Domain of Cbl Is Essential for Negative Regulation of the Syk Tyrosine KinaseQ58179986
The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptorQ73316781
Deletion mutagenesis of large (12-kb) plasmids by a one-step PCR protocolQ77073762
The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptorQ78069495
P433issue27
P407language of work or nameEnglishQ1860
P921main subjectSH3 domainQ24771787
P304page(s)4690-4706
P577publication date2004-06-01
P1433published inOncogeneQ1568657
P1476titleTULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin
P478volume23

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cites work (P2860)
Q27646954A Phosphatase Activity of Sts-1 Contributes to the Suppression of TCR Signaling
Q24644978A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3
Q24336773A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets
Q55293911A novel scoring system for gastric cancer risk assessment based on the expression of three CLIP4 DNA methylation-associated genes.
Q34987223Apoptosis-inducing factor: structure, function, and redox regulation
Q38084832Atypical protein phosphatases: emerging players in cellular signaling
Q24300886Cbl escapes Cdc42-mediated inhibition by downregulation of the adaptor molecule betaPix
Q28771482Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation
Q30159888Crystallization and initial crystal characterization of the C-terminal phosphoglycerate mutase homology domain of Sts-1.
Q53541598Decreased UBASH3A mRNA Expression Levels in Peripheral Blood Mononuclear Cells from Patients with Systemic Lupus Erythematosus.
Q33645197Determination of the Substrate Specificity of Protein-tyrosine Phosphatase TULA-2 and Identification of Syk as a TULA-2 Substrate
Q35835790E3 ligases in T cell anergy--turning immune responses into tolerance
Q33888849Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies
Q37588300FOXC2 and CLIP4 : a potential biomarker for synchronous metastasis of ≤7-cm clear cell renal cell carcinomas.
Q24308033Insights into the suppressor of T-cell receptor (TCR) signaling-1 (Sts-1)-mediated regulation of TCR signaling through the use of novel substrate-trapping Sts-1 phosphatase variants
Q42673182Members of the novel UBASH3/STS/TULA family of cellular regulators suppress T-cell-driven inflammatory responses in vivo
Q36870857Molecular mechanisms of CD4+ T-cell anergy
Q35868311Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation
Q35035235Quantitative phosphoproteome analysis unveils LAT as a modulator of CD3ζ and ZAP-70 tyrosine phosphorylation
Q34486954Regulation of ubiquitin-binding proteins by monoubiquitination
Q34524707SLI-1 Cbl inhibits the engulfment of apoptotic cells in C. elegans through a ligase-independent function
Q27653664Structural and Functional Characterization of the 2H-Phosphatase Domain of Sts-2 Reveals an Acid-Dependent Phosphatase Activity †
Q33644549Structures of the phosphorylated and VO(3)-bound 2H-phosphatase domain of Sts-2.
Q34963266Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways
Q30157759Suppressor of T-cell receptor signalling 1 and 2 differentially regulate endocytosis and signalling of receptor tyrosine kinases
Q48253116Suppressor of TCR signaling-2 (STS-2) suppresses arthritis development in mice
Q24658051T cell activation
Q34665121T-cell ubiquitin ligand affects cell death through a functional interaction with apoptosis-inducing factor, a key factor of caspase-independent apoptosis
Q34713979TULA proteins bind to ABCE-1, a host factor of HIV-1 assembly, and inhibit HIV-1 biogenesis in a UBA-dependent fashion.
Q28854385TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of Syk
Q28586059TULA-2, a novel histidine phosphatase, regulates bone remodeling by modulating osteoclast function
Q38017998TULA-family proteins: a new class of cellular regulators
Q37544376TULA-family proteins: an odd couple
Q37252710Tailoring T-cell receptor signals by proximal negative feedback mechanisms
Q30158019The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis
Q51577116The Extended Family of Protein Tyrosine Phosphatases.
Q38835640The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness.
Q38634867The extended human PTPome: a growing tyrosine phosphatase family
Q46476342The multidomain protooncogenic protein c-Cbl binds to tubulin and stabilizes microtubules
Q48290135UBASH3A Mediates Risk for Type 1 Diabetes Through Inhibition of T-Cell Receptor-Induced NF-κB Signaling
Q24306128Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment
Q34015771Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics
Q36280423c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses

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