scholarly article | Q13442814 |
P2093 | author name string | Reuben P Siraganian | |
Juan Zhang | |||
Rodrigo Orlandini de Castro | |||
Emilia Alina Barbu | |||
Jacqueline R Groves | |||
P2860 | cites work | Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes | Q24307359 |
The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development | Q24314695 | ||
A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets | Q24336773 | ||
Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein | Q24540267 | ||
Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5) | Q24595848 | ||
New developments in mast cell biology | Q24634390 | ||
The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network | Q24682994 | ||
Structural basis for the inhibition of tyrosine kinase activity of ZAP-70 | Q27644831 | ||
A Phosphatase Activity of Sts-1 Contributes to the Suppression of TCR Signaling | Q27646954 | ||
SH2 domains recognize specific phosphopeptide sequences | Q27860748 | ||
The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors | Q28137592 | ||
Mast cell signal transduction from the high-affinity IgE receptor | Q28186015 | ||
Purification and molecular cloning of SH2- and SH3-containing inositol polyphosphate-5-phosphatase, which is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor, erythropoietin, and Bcr-Abl | Q28235300 | ||
SLP-76 is a substrate of the high affinity IgE receptor-stimulated protein tyrosine kinases in rat basophilic leukemia cells | Q28301306 | ||
Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function | Q28513137 | ||
Phosphorylation of Syk activation loop tyrosines is essential for Syk function. An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibody | Q28573020 | ||
Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2 | Q28587191 | ||
Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk | Q28619124 | ||
Suppressor of T-cell receptor signalling 1 and 2 differentially regulate endocytosis and signalling of receptor tyrosine kinases | Q30157759 | ||
The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains. | Q30159822 | ||
Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases | Q30164059 | ||
TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin | Q30164133 | ||
The Nck family of adapter proteins: regulators of actin cytoskeleton | Q30165392 | ||
Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains | Q33226743 | ||
TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells | Q33304751 | ||
Small interfering RNA screen for phosphatases involved in IgE-mediated mast cell degranulation | Q33581708 | ||
Structures of the phosphorylated and VO(3)-bound 2H-phosphatase domain of Sts-2. | Q33644549 | ||
Determination of the Substrate Specificity of Protein-tyrosine Phosphatase TULA-2 and Identification of Syk as a TULA-2 Substrate | Q33645197 | ||
SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells | Q33853163 | ||
The limited contribution of Fyn and Gab2 to the high affinity IgE receptor signaling in mast cells | Q33855085 | ||
Calcium signaling in immune cells. | Q33878792 | ||
Tyrosines in the carboxyl terminus regulate Syk kinase activity and function | Q34074500 | ||
Competition between solution and cell surface receptors for ligand. Dissociation of hapten bound to surface antibody in the presence of solution antibody | Q34125217 | ||
Mast cell signaling: the role of protein tyrosine kinase Syk, its activation and screening methods for new pathway participants | Q34388351 | ||
Adapters in the organization of mast cell signaling | Q34476441 | ||
T-cell ubiquitin ligand affects cell death through a functional interaction with apoptosis-inducing factor, a key factor of caspase-independent apoptosis | Q34665121 | ||
TULA proteins bind to ABCE-1, a host factor of HIV-1 assembly, and inhibit HIV-1 biogenesis in a UBA-dependent fashion. | Q34713979 | ||
Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells | Q34784234 | ||
Protein tyrosine kinase Syk in mast cell signaling | Q34825330 | ||
Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways | Q34963266 | ||
Regulation and function of syk tyrosine kinase in mast cell signaling and beyond | Q35101718 | ||
The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation | Q36310121 | ||
Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane | Q36320717 | ||
Integrated signalling pathways for mast-cell activation | Q36392833 | ||
Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides | Q36557865 | ||
Quantitative time-resolved phosphoproteomic analysis of mast cell signaling | Q37307359 | ||
The Sts proteins target tyrosine phosphorylated, ubiquitinated proteins within TCR signaling pathways | Q37376318 | ||
Cooperation of adapter molecules in proximal signaling cascades during allergic inflammation | Q37631696 | ||
Autoinhibition and adapter function of Syk. | Q37631725 | ||
New insights into the structural mechanisms of the COPII coat | Q37673324 | ||
Coordination of receptor signaling in multiple hematopoietic cell lineages by the adaptor protein SLP-76 | Q37746483 | ||
TULA proteins regulate activity of the protein tyrosine kinase Syk. | Q40026226 | ||
Mutations in the activation loop tyrosines of protein tyrosine kinase Syk abrogate intracellular signaling but not kinase activity | Q41001738 | ||
The role of SHIP in mast cell degranulation and IgE-induced mast cell survival | Q43991319 | ||
T cell activation induced by novel gain-of-function mutants of Syk and ZAP-70. | Q47982347 | ||
IgE-induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones | Q52834043 | ||
Selective impairment of Fc RI-mediated allergic reaction in Gads-deficient mice | Q57949079 | ||
The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor | Q73343323 | ||
SHIP negatively regulates IgE + antigen-induced IL-6 production in mast cells by inhibiting NF-kappa B activity | Q77995921 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | mast cell | Q191989 |
phosphorylation | Q242736 | ||
P1104 | number of pages | 11 | |
P304 | page(s) | 8194-8204 | |
P577 | publication date | 2012-01-20 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation | |
P478 | volume | 287 |
Q38084832 | Atypical protein phosphatases: emerging players in cellular signaling |
Q37116141 | GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis |
Q40166404 | Increased Resistance to Intradermal Francisella tularensis LVS Infection by Inactivation of the Sts Phosphatases. |
Q24308033 | Insights into the suppressor of T-cell receptor (TCR) signaling-1 (Sts-1)-mediated regulation of TCR signaling through the use of novel substrate-trapping Sts-1 phosphatase variants |
Q92294516 | Interplay between HGAL and Grb2 proteins regulates B-cell receptor signaling |
Q26824984 | Mast cell activation: a complex interplay of positive and negative signaling pathways |
Q37564481 | MicroRNA-1291 targets the FOXA2-AGR2 pathway to suppress pancreatic cancer cell proliferation and tumorigenesis |
Q47334511 | Modulating Host Signaling Pathways to Promote Resistance to Infection by Candida albicans |
Q64991646 | Phagocytes from Mice Lacking the Sts Phosphatases Have an Enhanced Antifungal Response to Candida albicans. |
Q37066101 | Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells |
Q34955565 | Protection from systemic Candida albicans infection by inactivation of the Sts phosphatases |
Q51702653 | Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation. |
Q38799014 | Regulation of immune cell signaling by SHIP1: A phosphatase, scaffold protein, and potential therapeutic target. |
Q50291098 | Syk activation leads to SLP-76 activation |
Q93092263 | TULA-2 Deficiency Enhances Platelet Functional Responses to CLEC-2 Agonists |
Q28854385 | TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of Syk |
Q28586059 | TULA-2, a novel histidine phosphatase, regulates bone remodeling by modulating osteoclast function |
Q38634867 | The extended human PTPome: a growing tyrosine phosphatase family |
Q90623254 | The lectin ArtinM activates RBL-2H3 mast cells without inducing degranulation |
Q48007320 | Unperturbed Immune Function despite Mutation of C-Terminal Tyrosines in Syk Previously Implicated in Signaling and Activity Regulation |
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