review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Atsushi Tanaka | |
P2860 | cites work | PINK1 is selectively stabilized on impaired mitochondria to activate Parkin | Q21145802 |
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase | Q22254584 | ||
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin | Q24291412 | ||
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells | Q24291591 | ||
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 | Q24297155 | ||
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice | Q24303752 | ||
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism | Q24309753 | ||
Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling | Q24312963 | ||
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy | Q24317471 | ||
Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. | Q24541558 | ||
Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro | Q81597727 | ||
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy | Q24652230 | ||
Selective degradation of mitochondria by mitophagy | Q24658163 | ||
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy | Q27936161 | ||
Atg32 is a mitochondrial protein that confers selectivity during mitophagy | Q27936726 | ||
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice | Q28131756 | ||
Themes and variations on ubiquitylation | Q28206411 | ||
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin | Q29547423 | ||
Essential role for Nix in autophagic maturation of erythroid cells | Q29614480 | ||
NIX is required for programmed mitochondrial clearance during reticulocyte maturation | Q29614484 | ||
Chronic systemic pesticide exposure reproduces features of Parkinson's disease | Q29614763 | ||
The PINK1/Parkin pathway regulates mitochondrial morphology | Q29615641 | ||
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin | Q29615684 | ||
Disruption of fusion results in mitochondrial heterogeneity and dysfunction | Q29616566 | ||
Mitochondrial dynamics and apoptosis | Q29616570 | ||
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin | Q29617063 | ||
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila | Q29617091 | ||
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy | Q29620567 | ||
Dynamics and diversity in autophagy mechanisms: lessons from yeast | Q29620685 | ||
alpha-Synuclein and parkin: coming together of pieces in puzzle of Parkinson's disease | Q33336648 | ||
Parkinson's disease: from causes to mechanisms | Q36072236 | ||
Oxidative stress and inflammation in Parkinson's disease: is there a causal link? | Q36115736 | ||
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery | Q36657599 | ||
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation | Q36835194 | ||
Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes | Q37014368 | ||
Outer mitochondrial membrane protein degradation by the proteasome | Q37030094 | ||
Protein degradation in Parkinson disease revisited: it's complex | Q37111325 | ||
The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases | Q37336182 | ||
Mitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic models | Q37356319 | ||
Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease | Q37419672 | ||
Progression of Parkinson's disease in the clinical phase: potential markers | Q37631962 | ||
The role of dopamine oxidation in mitochondrial dysfunction: implications for Parkinson's disease | Q37646362 | ||
The PINK1/Parkin pathway: a mitochondrial quality control system? | Q37646370 | ||
Parkin-induced mitophagy in the pathogenesis of Parkinson disease | Q39859240 | ||
Ordered bulk degradation via autophagy. | Q39942252 | ||
Parkin protects against tyrosinase-mediated dopamine neurotoxicity by suppressing stress-activated protein kinase pathways. | Q40016819 | ||
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. | Q40670474 | ||
Differential function and expression of the viral inhibitor of caspase 8-induced apoptosis (vICA) and the viral mitochondria-localized inhibitor of apoptosis (vMIA) cell death suppressors conserved in primate and rodent cytomegaloviruses | Q42833665 | ||
Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA. | Q45878904 | ||
Parkin: a multifaceted ubiquitin ligase. | Q51116287 | ||
The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process. | Q52695435 | ||
Aberrant Folding of Pathogenic Parkin Mutants | Q60290972 | ||
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | autophagy | Q288322 |
mitochondrion | Q39572 | ||
P304 | page(s) | 1386-1392 | |
P577 | publication date | 2010-02-25 | |
P1433 | published in | FEBS Letters | Q1388051 |
P1476 | title | Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network | |
P478 | volume | 584 |
Q98464865 | A Crucial Role for the Protein Quality Control System in Motor Neuron Diseases |
Q36608848 | Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanisms |
Q38084832 | Atypical protein phosphatases: emerging players in cellular signaling |
Q38264793 | Autophagy in neuronal cells: general principles and physiological and pathological functions |
Q36194770 | Autophagy is induced through the ROS-TP53-DRAM1 pathway in response to mitochondrial protein synthesis inhibition |
Q40088555 | BNIP3L/NIX-mediated mitophagy protects against ischemic brain injury independent of PARK2. |
Q59812436 | Brain SIRT1 Mediates Metabolic Homeostasis and Neuroprotection |
Q26823387 | Cell death and survival through the endoplasmic reticulum-mitochondrial axis |
Q41889273 | Collapsin response mediator protein 5 (CRMP5) induces mitophagy, thereby regulating mitochondrion numbers in dendrites |
Q36037330 | Comparison of the structure, function and autophagic maintenance of mitochondria in nigrostriatal and tuberoinfundibular dopamine neurons |
Q90351808 | Contribution of Tau Pathology to Mitochondrial Impairment in Neurodegeneration |
Q39978117 | Cyclosporine A Treatment Abrogates Ischemia-Induced Neuronal Cell Death by Preserving Mitochondrial Integrity through Upregulation of the Parkinson's Disease-Associated Protein DJ-1. |
Q37466859 | Equine metabolic syndrome impairs adipose stem cells osteogenic differentiation by predominance of autophagy over selective mitophagy |
Q60695461 | Exploring the Role of Autophagy in the Pathogenesis of Rotenone-induced Toxicity |
Q37782017 | From signal transduction to autophagy of plant cell organelles: lessons from yeast and mammals and plant-specific features |
Q42564297 | Impaired parkin-mediated mitochondrial targeting to autophagosomes differentially contributes to tissue pathology in lysosomal storage diseases |
Q42125967 | Mao-B elevation decreases parkin's ability to efficiently clear damaged mitochondria: protective effects of rapamycin |
Q24338231 | Microtubule-associated protein 1S (MAP1S) bridges autophagic components with microtubules and mitochondria to affect autophagosomal biogenesis and degradation |
Q28586980 | Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome |
Q28575545 | Mitochondrial autophagy involving renal injury and aging is modulated by caloric intake in aged rat kidneys |
Q35359238 | Mitochondrial contagion induced by Parkin deficiency in Drosophila hearts and its containment by suppressing mitofusin |
Q38021396 | Mitochondrial dynamics: the intersection of form and function |
Q36539066 | Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue |
Q35799109 | Mitochondrial dysfunction in genetic animal models of Parkinson's disease |
Q41673213 | Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer's Disease-Associated Presenilin 1 Mutation. |
Q59798974 | Mitophagy, a potential therapeutic target for stroke |
Q36939452 | Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects |
Q35768699 | Opposing effects of age and calorie restriction on molecular determinants of myocardial ischemic tolerance |
Q37580505 | Parkin deficiency exacerbate ethanol-induced dopaminergic neurodegeneration by P38 pathway dependent inhibition of autophagy and mitochondrial function |
Q42235376 | Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane |
Q47810725 | Parkin regulates lipopolysaccharide-induced proinflammatory responses in acute lung injury |
Q38690404 | Parkin reverses TDP-43-induced cell death and failure of amino acid homeostasis |
Q92188247 | Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff) |
Q37874160 | Parkinson's disease mouse models in translational research |
Q49425463 | Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin |
Q47216699 | Regulation of mitophagy by the ubiquitin pathway in neurodegenerative diseases |
Q42051309 | Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5 |
Q38109587 | Selective autophagy: talking with the UPS. |
Q34611134 | Sustained activation of Akt elicits mitochondrial dysfunction to block Plasmodium falciparum infection in the mosquito host |
Q34689753 | Synaptic mitochondria in synaptic transmission and organization of vesicle pools in health and disease |
Q24316726 | The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy |
Q37855544 | The Relationship between Parkin and Protein Aggregation in Neurodegenerative Diseases |
Q38537990 | The receptor proteins: pivotal roles in selective autophagy |
Q36014614 | Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy |
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