Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network

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Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.FEBSLET.2010.02.060
P932PMC publication ID2843751
P698PubMed publication ID20188730
P5875ResearchGate publication ID41621317

P2093author name stringAtsushi Tanaka
P2860cites workPINK1 is selectively stabilized on impaired mitochondria to activate ParkinQ21145802
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligaseQ22254584
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of ParkinQ24291412
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cellsQ24291591
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1Q24297155
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient miceQ24303752
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonismQ24309753
Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signalingQ24312963
Parkin is recruited selectively to impaired mitochondria and promotes their autophagyQ24317471
Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.Q24541558
Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitroQ81597727
Fission and selective fusion govern mitochondrial segregation and elimination by autophagyQ24652230
Selective degradation of mitochondria by mitophagyQ24658163
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagyQ27936161
Atg32 is a mitochondrial protein that confers selectivity during mitophagyQ27936726
Suppression of basal autophagy in neural cells causes neurodegenerative disease in miceQ28131756
Themes and variations on ubiquitylationQ28206411
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkinQ29547423
Essential role for Nix in autophagic maturation of erythroid cellsQ29614480
NIX is required for programmed mitochondrial clearance during reticulocyte maturationQ29614484
Chronic systemic pesticide exposure reproduces features of Parkinson's diseaseQ29614763
The PINK1/Parkin pathway regulates mitochondrial morphologyQ29615641
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkinQ29615684
Disruption of fusion results in mitochondrial heterogeneity and dysfunctionQ29616566
Mitochondrial dynamics and apoptosisQ29616570
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by ParkinQ29617063
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in DrosophilaQ29617091
PINK1-dependent recruitment of Parkin to mitochondria in mitophagyQ29620567
Dynamics and diversity in autophagy mechanisms: lessons from yeastQ29620685
alpha-Synuclein and parkin: coming together of pieces in puzzle of Parkinson's diseaseQ33336648
Parkinson's disease: from causes to mechanismsQ36072236
Oxidative stress and inflammation in Parkinson's disease: is there a causal link?Q36115736
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machineryQ36657599
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturationQ36835194
Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomesQ37014368
Outer mitochondrial membrane protein degradation by the proteasomeQ37030094
Protein degradation in Parkinson disease revisited: it's complexQ37111325
The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseasesQ37336182
Mitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic modelsQ37356319
Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's diseaseQ37419672
Progression of Parkinson's disease in the clinical phase: potential markersQ37631962
The role of dopamine oxidation in mitochondrial dysfunction: implications for Parkinson's diseaseQ37646362
The PINK1/Parkin pathway: a mitochondrial quality control system?Q37646370
Parkin-induced mitophagy in the pathogenesis of Parkinson diseaseQ39859240
Ordered bulk degradation via autophagy.Q39942252
Parkin protects against tyrosinase-mediated dopamine neurotoxicity by suppressing stress-activated protein kinase pathways.Q40016819
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.Q40670474
Differential function and expression of the viral inhibitor of caspase 8-induced apoptosis (vICA) and the viral mitochondria-localized inhibitor of apoptosis (vMIA) cell death suppressors conserved in primate and rodent cytomegalovirusesQ42833665
Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA.Q45878904
Parkin: a multifaceted ubiquitin ligase.Q51116287
The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.Q52695435
Aberrant Folding of Pathogenic Parkin MutantsQ60290972
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
mitochondrionQ39572
P304page(s)1386-1392
P577publication date2010-02-25
P1433published inFEBS LettersQ1388051
P1476titleParkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network
P478volume584

Reverse relations

cites work (P2860)
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Q36014614Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy

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