Prevention of apoptosis by mitochondrial phosphatase PGAM5 in the mushroom body is crucial for heat shock resistance in Drosophila melanogaster

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Prevention of apoptosis by mitochondrial phosphatase PGAM5 in the mushroom body is crucial for heat shock resistance in Drosophila melanogaster is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...730265I
P356DOI10.1371/JOURNAL.PONE.0030265
P932PMC publication ID3274544
P698PubMed publication ID22347370
P5875ResearchGate publication ID221844772

P50authorKohsuke TakedaQ55292968
Yusuke SekineQ57320794
Hidenori IchijōQ37376351
P2093author name stringMasayuki Miura
Takahiro Chihara
Yosuke Ishida
Haruka Oguchi
P2860cites workIn situ trapping of activated initiator caspases reveals a role for caspase-2 in heat shock-induced apoptosis.Q50744961
Neuronal assemblies of the Drosophila mushroom body.Q51960163
Transcriptional regulation of the Drosophila glial gene repo.Q52047804
Caspase inhibition during apoptosis causes abnormal signalling and developmental aberrations in Drosophila.Q52086513
Subdivision of the Drosophila mushroom bodies by enhancer-trap expression patterns.Q52207413
Heritable gene silencing in Drosophila using double-stranded RNA.Q52581458
Sibling cell fate in the Drosophila adult external sense organ lineage is specified by prospero function, which is regulated by Numb and NotchQ77336632
Stress-induced germ cell apoptosis by a p53 independent pathway in Caenorhabditis elegansQ83855433
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkinQ29615684
Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesisQ29615747
Live imaging of wound inflammation in Drosophila embryos reveals key roles for small GTPases during in vivo cell migrationQ30777752
In vitro selection and characterization of Bcl-X(L)-binding proteins from a mix of tissue-specific mRNA display librariesQ31889951
The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in DrosophilaQ33769553
Conditional modification of behavior in Drosophila by targeted expression of a temperature-sensitive shibire allele in defined neuronsQ33941654
Activation of caspase-9, but not caspase-2 or caspase-8, is essential for heat-induced apoptosis in Jurkat cellsQ34412566
Mushroom bodies suppress locomotor activity in Drosophila melanogasterQ35038876
'Heated' debates in apoptosisQ36850786
Temporal regulation of Drosophila IAP1 determines caspase functions in sensory organ development.Q37402337
The heat shock response: life on the verge of deathQ37802041
A Drosophila p38 orthologue is required for environmental stress responsesQ40106380
PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complexQ40219081
Bax-like protein Drob-1 protects neurons from expanded polyglutamine-induced toxicity in DrosophilaQ42921737
Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosisQ43796120
Targeted gene expression in Drosophila dopaminergic cells using regulatory sequences from tyrosine hydroxylaseQ44295075
The Drosophila dual-specificity ERK phosphatase DMKP3 cooperates with the ERK tyrosine phosphatase PTP-ER.Q44480683
Mushroom bodies enhance initial motor activity in DrosophilaQ46162036
Pan-neuronal knockdown of calcineurin reduces sleep in the fruit fly, Drosophila melanogaster.Q47070949
Generation of medial and lateral dorsal body domains by the pannier gene of DrosophilaQ47072816
Blockade of neurotransmission in Drosophila mushroom bodies impairs odor attraction, but not repulsionQ48158055
Associative odor learning in Drosophila abolished by chemical ablation of mushroom bodiesQ48175515
A dynamic role for the mushroom bodies in promoting sleep in DrosophilaQ48497900
Associative learning disrupted by impaired Gs signaling in Drosophila mushroom bodiesQ48828469
Mushroom body memoir: from maps to modelsQ22337225
Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1Q24312673
PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondriaQ28384526
Thermal disruption of mushroom body development and odor learning in DrosophilaQ28471615
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectDrosophila melanogasterQ130888
apoptotic processQ14599311
Phosphoglycerate mutase 5 Dmel_CG14816Q29810155
P304page(s)e30265
P577publication date2012-02-07
P1433published inPLOS OneQ564954
P1476titlePrevention of apoptosis by mitochondrial phosphatase PGAM5 in the mushroom body is crucial for heat shock resistance in Drosophila melanogaster
P478volume7