scholarly article | Q13442814 |
retracted paper | Q45182324 |
P2093 | author name string | Suryakant K Niture | |
Anil K Jaiswal | |||
P2860 | cites work | Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice | Q23923904 |
The Hallmarks of Cancer | Q221226 | ||
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death | Q24312157 | ||
Enrolling women into HIV preventive vaccine trials: an ethical imperative but a logistical challenge | Q25255907 | ||
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death | Q27733156 | ||
Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain. Inhibition of nuclear translocation and transacting function | Q28239381 | ||
Cell death: critical control points | Q28240722 | ||
Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein | Q28283167 | ||
An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen | Q28361995 | ||
PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria | Q28384526 | ||
Nrf2 signaling and cell survival | Q28394210 | ||
Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer | Q28469051 | ||
Bcl-XL and Bcl-2 repress a common pathway of cell death | Q28505812 | ||
The Bcl2 family: regulators of the cellular life-or-death switch | Q29614982 | ||
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice | Q29615438 | ||
Nrf2:INrf2 (Keap1) signaling in oxidative stress | Q29615712 | ||
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer | Q29616499 | ||
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation | Q29618051 | ||
Apoptotic molecular machinery: vastly increased complexity in vertebrates revealed by genome comparisons | Q30658935 | ||
In vitro selection and characterization of Bcl-X(L)-binding proteins from a mix of tissue-specific mRNA display libraries | Q31889951 | ||
An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance | Q33967398 | ||
Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis | Q33981477 | ||
INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis | Q34441957 | ||
Bad-deficient mice develop diffuse large B cell lymphoma | Q35234507 | ||
Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice | Q36402881 | ||
KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta | Q37406535 | ||
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival | Q38359163 | ||
Prothymosin-alpha mediates nuclear import of the INrf2/Cul3 Rbx1 complex to degrade nuclear Nrf2. | Q39874226 | ||
An auto-regulatory loop between stress sensors INrf2 and Nrf2 controls their cellular abundance. | Q40070103 | ||
PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex | Q40219081 | ||
Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate | Q40236612 | ||
Nuclear oncoprotein prothymosin alpha is a partner of Keap1: implications for expression of oxidative stress-protecting genes. | Q40890652 | ||
Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust | Q43662015 | ||
Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema | Q47680966 | ||
P433 | issue | 52 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
P304 | page(s) | 44542-56 | |
P577 | publication date | 2011-12-30 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Inhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosis | |
P478 | volume | 286 |
Q34139093 | A conserved motif mediates both multimer formation and allosteric activation of phosphoglycerate mutase 5. |
Q36548027 | Aberrant Keap1 methylation in breast cancer and association with clinicopathological features |
Q34448170 | Activating Nrf-2 signaling depresses unilateral ureteral obstruction-evoked mitochondrial stress-related autophagy, apoptosis and pyroptosis in kidney |
Q36608829 | An Essential Role of NRF2 in Diabetic Wound Healing |
Q36299738 | An increase in glucosylceramide synthase induces Bcl-xL-mediated cell survival in vinorelbine-resistant lung adenocarcinoma cells |
Q39016220 | Antiapoptotic potency of Bcl-2 proteins primarily relies on their stability, not binding selectivity. |
Q42699511 | Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic factor Bcl-2 in human keratinocytes |
Q38084832 | Atypical protein phosphatases: emerging players in cellular signaling |
Q40254604 | Bcl-xL mediates RIPK3-dependent necrosis in M. tuberculosis-infected macrophages |
Q46290264 | Carboxyethylgermanium sesquioxide (Ge-132) treatment during in vitro culture protects fertilized porcine embryos against oxidative stress induced apoptosis |
Q35778758 | Cell signalling by reactive lipid species: new concepts and molecular mechanisms |
Q92077343 | Cellular demolition: Proteins as molecular players of programmed cell death |
Q28393784 | Cytoprotection "gone astray": Nrf2 and its role in cancer |
Q39000961 | Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis |
Q64093479 | Downregulation of Keap1 contributes to poor prognosis and Axitinib resistance of renal cell carcinoma via upregulation of Nrf2 expression |
Q26996150 | Emerging functional cross-talk between the Keap1-Nrf2 system and mitochondria |
Q38398064 | Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment. |
Q36702748 | Functions of BCL-X L at the Interface between Cell Death and Metabolism |
Q58700394 | High PGAM5 expression induces chemoresistance by enhancing Bcl-xL-mediated anti-apoptotic signaling and predicts poor prognosis in hepatocellular carcinoma patients |
Q96773385 | Inhibiting the inhibitors: Targeting anti-apoptotic proteins in cancer and therapy resistance |
Q34997448 | Insight into the intermolecular recognition mechanism between Keap1 and IKKβ combining homology modelling, protein-protein docking, molecular dynamics simulations and virtual alanine mutation |
Q37025047 | KEAP1 is a redox sensitive target that arbitrates the opposing radiosensitive effects of parthenolide in normal and cancer cells |
Q38022427 | Keap1: one stone kills three birds Nrf2, IKKβ and Bcl-2/Bcl-xL. |
Q91740424 | Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing |
Q40463091 | Mitochondrial phosphatase PGAM5 regulates Keap1-mediated Bcl-xL degradation and controls cardiomyocyte apoptosis driven by myocardial ischemia/reperfusion injury. |
Q38949868 | Multitarget effects of quercetin in leukemia. |
Q42730519 | NRF2 Is a Potential Modulator of Hyperresistance to Arsenic Toxicity in Stem-Like Keratinocytes |
Q39217937 | Nrf2-induced antiapoptotic Bcl-xL protein enhances cell survival and drug resistance |
Q38116378 | Nuclear erythroid 2-related factor 2: a novel potential therapeutic target for liver fibrosis |
Q37497152 | Oleanolic acid attenuates renal fibrosis in mice with unilateral ureteral obstruction via facilitating nuclear translocation of Nrf2. |
Q38997210 | Protein phosphatase 6 controls BCR-induced apoptosis of WEHI-231 cells by regulating ubiquitination of Bcl-xL. |
Q28388589 | Regulation of Nrf2-an update |
Q42702710 | Solanesol protects human hepatic L02 cells from ethanol-induced oxidative injury via upregulation of HO-1 and Hsp70. |
Q91981259 | Sulforaphane improves voiding function via the preserving mitochondrial function in diabetic rats |
Q38768832 | Tert-butylhydroquinone attenuates the ethanol-induced apoptosis of and activates the Nrf2 antioxidant defense pathway in H9c2 cardiomyocytes |
Q38295523 | The Keap1-Nrf2-antioxidant response element pathway: a review of its regulation by melatonin and the proteasome. |
Q27682227 | The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway |
Q36386948 | The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages. |
Q21285141 | The phosphorylation-dependent regulation of mitochondrial proteins in stress responses |
Q93032488 | Viral-mediated gene delivery of TMBIM6 protects the neonatal brain via disruption of NPR-CYP complex coupled with upregulation of Nrf-2 post-HI |
Q91046518 | p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2 |
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