| scholarly article | Q13442814 |
| P2093 | author name string | Weiping Wang | |
| Jefferson Y Chan | |||
| P2860 | cites work | Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 |
| Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome | Q35974394 | ||
| Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation | Q36038160 | ||
| Membrane-associated and secreted genes in breast cancer | Q40485741 | ||
| Role of NRF2 in protection against hyperoxic lung injury in mice | Q43862673 | ||
| Signal sequences: more than just greasy peptides | Q56639128 | ||
| Isolation of cDNA clones encoding T cell-specific membrane-associated proteins | Q59067678 | ||
| ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1 | Q22254333 | ||
| Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice | Q24317348 | ||
| Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast | Q24321410 | ||
| CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P. | Q24338672 | ||
| BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase | Q24558689 | ||
| Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region | Q24563505 | ||
| Isolation of cDNA encoding the human NF-E2 protein | Q24563782 | ||
| Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2 | Q24563807 | ||
| Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain | Q24609907 | ||
| Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site | Q24647985 | ||
| The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts | Q28140598 | ||
| TCF11/Nrf1 overexpression increases the intracellular glutathione level and can transactivate the gamma-glutamylcysteine synthetase (GCS) heavy subunit promoter | Q28187746 | ||
| Cellular localisation and nuclear export of the human bZIP transcription factor TCF11 | Q28202272 | ||
| Two domains of the human bZIP transcription factor TCF11 are necessary for transactivation | Q28207753 | ||
| Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron | Q28261724 | ||
| Nrf2 is essential for protection against acute pulmonary injury in mice | Q28343659 | ||
| An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen | Q28361995 | ||
| OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes | Q28580776 | ||
| Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1 | Q28583647 | ||
| Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes | Q28611357 | ||
| ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response | Q28611502 | ||
| An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
| Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice | Q29615438 | ||
| Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression | Q29615644 | ||
| The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase | Q29616502 | ||
| Regulatory mechanisms controlling gene expression mediated by the antioxidant response element | Q29616504 | ||
| Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors | Q29616505 | ||
| Evidence for a role of CRM1 in signal-mediated nuclear protein export | Q29620231 | ||
| Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein | Q29620253 | ||
| High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes | Q31783158 | ||
| Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism | Q33836992 | ||
| Oxidative stress: oxidants and antioxidants | Q34064540 | ||
| Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress | Q34229596 | ||
| Regulating inducible transcription through controlled localization | Q34419611 | ||
| P433 | issue | 28 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endoplasmic reticulum | Q79927 |
| transmembrane protein | Q424204 | ||
| P304 | page(s) | 19676-87 | |
| P577 | publication date | 2006-07-14 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain. Inhibition of nuclear translocation and transacting function | |
| P478 | volume | 281 |
| Q38289898 | A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways |
| Q55484374 | Antioxidant response elements: Discovery, classes, regulation and potential applications. |
| Q37355365 | BNIP3 mediates cell death by different pathways following localization to endoplasmic reticulum and mitochondrion |
| Q28384122 | Bioanalysis of eukaryotic organelles |
| Q48106093 | Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity. |
| Q28587680 | Characterization of Nrf1b, a novel isoform of the nuclear factor-erythroid-2 related transcription factor-1 that activates antioxidant response element-regulated genes |
| Q33574880 | Cyanide-induced apoptosis of dopaminergic cells is promoted by BNIP3 and Bax modulation of endoplasmic reticulum-mitochondrial Ca2+ levels |
| Q28386665 | Dietary chemoprevention strategies for induction of phase II xenobiotic-metabolizing enzymes in lung carcinogenesis: A review |
| Q28247844 | Dual regulation of the transcriptional activity of Nrf1 by β-TrCP- and Hrd1-dependent degradation mechanisms |
| Q64074440 | Dynamic Regulation of Proteasome Expression |
| Q92972669 | Dynamic Regulation of the 26S Proteasome: From Synthesis to Degradation |
| Q42099362 | Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications |
| Q34708452 | Endoplasmic reticulum association and N-linked glycosylation of the human Nrf3 transcription factor |
| Q64054426 | Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity |
| Q90060996 | Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments |
| Q26864265 | Glutathione synthesis |
| Q28289761 | Glycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1 |
| Q24337727 | Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity |
| Q33826009 | Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells. |
| Q34441957 | INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis |
| Q38746625 | Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate |
| Q28256252 | Induction of Herpud1 expression by ER stress is regulated by Nrf1 |
| Q39741359 | Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to cholestatic liver injury in mice |
| Q28395156 | Inhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosis |
| Q27320819 | Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf |
| Q39579939 | KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response |
| Q28382872 | Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2 |
| Q47279133 | Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2). |
| Q28292085 | Long isoforms of NRF1 contribute to arsenic-induced antioxidant response in human keratinocytes |
| Q33404881 | MCRS2 represses the transactivation activities of Nrf1. |
| Q33763536 | Mechanisms and functions of Nrf2 signaling in Drosophila |
| Q28394732 | Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease |
| Q38909954 | Mitochondrial biogenesis and clearance: a balancing act. |
| Q37073173 | Molecular mechanisms of Nrf2-mediated antioxidant response |
| Q34274999 | NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1β genes |
| Q34193909 | NFE2L3 (NRF3): the Cinderella of the Cap'n'Collar transcription factors |
| Q34641803 | Natural antioxidants exhibit chemopreventive characteristics through the regulation of CNC b-Zip transcription factors in estrogen-induced breast carcinogenesis |
| Q28254462 | Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum |
| Q28295619 | Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes |
| Q38309430 | Nrf1 and Nrf2 transcription factors regulate androgen receptor transactivation in prostate cancer cells |
| Q45043665 | Nrf1 can be processed and activated in a proteasome-independent manner |
| Q50422243 | Nrf2 activation attenuates genetic endoplasmic reticulum stress induced by a mutation in the phosphomannomutase 2 gene in zebrafish. |
| Q24296827 | Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy |
| Q28398010 | Nrf2 and Nrf2-related proteins in development and developmental toxicity: Insights from studies in zebrafish (Danio rerio) |
| Q39599379 | Nrf2 in toxicology and pharmacology: the good, the bad and the ugly? |
| Q64108343 | Nrf2/Keap1 Mediated Redox Signaling Supports Synaptic Function and Longevity and Impacts on Circadian Activity |
| Q38762571 | Nuclear Factor Erythroid-2 Like 1 (NFE2L1): Structure, function and regulation |
| Q38681132 | Nuclear factor erythroid-2 related factor 2 (Nrf2)-mediated protein quality control in cardiomyocytes. |
| Q58778244 | O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1 |
| Q90432993 | Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes |
| Q33878865 | PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation |
| Q40219081 | PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex |
| Q28295179 | Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop |
| Q39352782 | Proteasome Structure and Assembly |
| Q41740375 | Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1. |
| Q90015434 | Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression |
| Q35408665 | Proteotoxic crisis, the ubiquitin-proteasome system, and cancer therapy |
| Q33418304 | Regulation of clock-controlled genes in mammals |
| Q24655260 | Regulation of glutathione synthesis |
| Q28392708 | Regulation of proteasome activity in health and disease |
| Q24629339 | Role of Nrf1 in antioxidant response element-mediated gene expression and beyond |
| Q34998380 | SKN-1/Nrf, a new unfolded protein response factor? |
| Q89720626 | Salivary epigenetic biomarkers as predictors of emerging childhood obesity |
| Q28384783 | Stress-activated cap'n'collar transcription factors in aging and human disease |
| Q104286529 | Stressful development: Integrating endoderm development, stress, and longevity |
| Q35985845 | TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells |
| Q92701031 | The Best for the Most Important: Maintaining a Pristine Proteome in Stem and Progenitor Cells |
| Q27341433 | The C-terminal domain of Nrf1 negatively regulates the full-length CNC-bZIP factor and its shorter isoform LCR-F1/Nrf1β; both are also inhibited by the small dominant-negative Nrf1γ/δ isoforms that down-regulate ARE-battery gene expression |
| Q28249259 | The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis |
| Q41921331 | The NHB1 (N-terminal homology box 1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its asparagine-glycosylation. |
| Q28256645 | The Nrf1 CNC-bZIP protein is regulated by the proteasome and activated by hypoxia |
| Q37006310 | The endoplasmic reticulum and the unfolded protein response |
| Q38054629 | The generation, detection, and effects of reactive drug metabolites |
| Q36935239 | The membrane-topogenic vectorial behaviour of Nrf1 controls its post-translational modification and transactivation activity |
| Q38166575 | The nrf1 and nrf2 balance in oxidative stress regulation and androgen signaling in prostate cancer cells |
| Q28235174 | The p65 isoform of Nrf1 is a dominant negative inhibitor of ARE-mediated transcription |
| Q33763635 | The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo |
| Q35740930 | Toxicogenomics of endoplasmic reticulum stress inducer tunicamycin in the small intestine and liver of Nrf2 knockout and C57BL/6J mice |
| Q28279454 | Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells |
| Q28245245 | Transcription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymes |
| Q57301712 | Transcriptional regulation of the 26S proteasome by Nrf1 |
| Q27012468 | mTORC1 signaling activates NRF1 to increase cellular proteasome levels |
| Q28306282 | p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition |
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